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Systematic Reviews & Meta-analysis

Interventions for the management of transient tachypnea of the newborn ‐ an overview of systematic reviews.

25 Feb, 2022 | 11:12h | UTC

Interventions for the management of transient tachypnoea of the newborn ‐ an overview of systematic reviews – Cochrane Library

 


Systematic Review: Effect of asthma education on health outcomes in children.

25 Feb, 2022 | 11:09h | UTC

Effect of asthma education on health outcomes in children: a systematic review – Archives of Disease in Childhood

 


M-A: Fetal and maternal outcomes after maternal biologic use during conception and pregnancy.

25 Feb, 2022 | 10:43h | UTC

Fetal and maternal outcomes after maternal biologic use during conception and pregnancy: a systematic review and meta-analysis – BJOG

 


Acute pancreatitis in pregnancy: meta-analysis of maternal and fetal outcomes.

25 Feb, 2022 | 10:39h | UTC

Acute pancreatitis in pregnancy: meta-analysis of maternal and fetal outcomes – British Journal of Surgery

 

Commentary on Twitter

 


Ambient air pollution and cardiovascular diseases: An umbrella review of systematic reviews and meta-analyses.

25 Feb, 2022 | 10:25h | UTC

Ambient air pollution and cardiovascular diseases: An umbrella review of systematic reviews and meta-analyses – Journal of Internal Medicine

 


M-A: Secondary cytoreductive surgery in platinum-sensitive recurrent ovarian cancer.

24 Feb, 2022 | 10:02h | UTC

Secondary Cytoreductive Surgery in Platinum-Sensitive Recurrent Ovarian Cancer: A Meta-Analysis – Journal of Clinical Oncology (link to abstract – $ for full-text)

Commentary: Meta-Analysis Affirms Survival Benefit of Second Surgery in Ovarian Cancer — Mortality decreased with rising rates of complete, optimal cytoreduction at recurrence – MedPage Today (free registration required)

Related:

RCT: Cytoreductive surgery for relapsed ovarian cancer.

Guide to enhanced recovery for cancer patients undergoing surgery: ERAS for Patients Undergoing Cytoreductive Surgery with or Without hyperthermic intraperitoneal chemotherapy.

 


Systematic Review: Weekly versus tri‐weekly paclitaxel with carboplatin for first‐line treatment in women with epithelial ovarian cancer.

23 Feb, 2022 | 10:05h | UTC

Weekly versus tri‐weekly paclitaxel with carboplatin for first‐line treatment in women with epithelial ovarian cancer – Cochrane Library

Summary: Does weekly dosing of paclitaxel improve survival, compared with tri-weekly dosing of paclitaxel in the initial treatment of ovarian cancer? – Cochrane Library

 


M-A: Combining antidepressants vs. antidepressant monotherapy for treatment of patients with acute depression.

22 Feb, 2022 | 08:40h | UTC

Combining Antidepressants vs Antidepressant Monotherapy for Treatment of Patients With Acute Depression: A Systematic Review and Meta-analysis – JAMA Psychiatry (free for a limited period)

 


M-A: Interventions to prevent spontaneous preterm birth in women with singleton pregnancy who are at high risk.

22 Feb, 2022 | 08:39h | UTC

Interventions to prevent spontaneous preterm birth in women with singleton pregnancy who are at high risk: systematic review and network meta-analysis – The BMJ

 


M-A of randomized trials | Association between intensity of LDL cholesterol reduction with statin-based therapies and secondary stroke prevention.

22 Feb, 2022 | 08:37h | UTC

Association Between Intensity of Low-Density Lipoprotein Cholesterol Reduction With Statin-Based Therapies and Secondary Stroke Prevention: A Meta-analysis of Randomized Clinical Trials – JAMA Neurology

Editorial: Low-Density Lipoprotein Cholesterol Level After a Stroke—Reducing It by Any Means (free for a limited period)

 


Meta-analysis of randomized trials | Efficacy and safety of transcutaneous electrical nerve stimulation (TENS) for acute and chronic pain in adults.

22 Feb, 2022 | 08:32h | UTC

Efficacy and safety of transcutaneous electrical nerve stimulation (TENS) for acute and chronic pain in adults: a systematic review and meta-analysis of 381 studies (the meta-TENS study) – BMJ Open

 


M-A: Diagnostic features, management and prognosis of type 2 myocardial infarction compared to type 1 myocardial infarction.

22 Feb, 2022 | 08:34h | UTC

Diagnostic features, management and prognosis of type 2 myocardial infarction compared to type 1 myocardial infarction: a systematic review and meta-analysis – BMJ Open

 


M-A: In patients with transient ischemic attack (TIA), referral to a TIA clinic that can provide urgent investigation and initiation of preventive measures may be as effective for preventing stroke compared to impatient care.

18 Feb, 2022 | 08:29h | UTC

Risk of Subsequent Stroke Among Patients Receiving Outpatient vs Inpatient Care for Transient Ischemic Attack: A Systematic Review and Meta-analysis – JAMA Network Open

 


M-A: Association of physician continuous professional development and referrals.

18 Feb, 2022 | 08:27h | UTC

Association of Physician Continuous Professional Development and Referrals: A Systematic Review and Meta-Analysis – Academic Medicine

 


M-A: Comparative effectiveness and safety of polyethylene glycol electrolyte solution vs. lactulose for the treatment of hepatic encephalopathy.

18 Feb, 2022 | 08:18h | UTC

Comparative Effectiveness and Safety of Polyethylene Glycol Electrolyte Solution Versus Lactulose for Treatment of Hepatic Encephalopathy: A Systematic Review and Meta-analysis – Journal of Clinical Gastroenterology

 


Meta-analysis finds the overall prevalence of statin intolerance is around 9% and identifies the most common risk factors.

17 Feb, 2022 | 10:07h | UTC

Prevalence of statin intolerance: a meta-analysis – European Heart Journal

Commentaries:

Study shows the true prevalence of statin intolerance worldwide is between 6 to 10% – News Medical / European Society of Cardiology

Expert reaction to study looking at statin intolerance – Science Media Centre

Related:

Side effect patterns in a crossover trial of statin, placebo, and no treatment – This N-of-1 trial, now published in full, suggests the nocebo effect causes most of statins muscle adverse effects.

#AHA20 – In patients who had discontinued statins because of side effects, a N-of-1 trial of a statin, placebo, or no treatment found that side effects often attributed to statins were the same for those taking a placebo

 

Commentary on Twitter

 


Management of the first stage of convulsive status epilepticus in adults: a systematic review of current randomized evidence.

17 Feb, 2022 | 08:37h | UTC

Management of the first stage of convulsive status epilepticus in adults: a systematic review of current randomised evidence – Journal of Neurology

 


Prone positioning during venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a pooled individual patient data analysis.

17 Feb, 2022 | 08:19h | UTC

Prone positioning during venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a pooled individual patient data analysis – Critical Care

 


M-A: Surgical interventions for treating extracapsular hip fractures in older adults.

16 Feb, 2022 | 08:44h | UTC

Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis – Cochrane Library

Summary: Which are the best treatments for hip fractures in older adults? – Cochrane Library

Author Interview: Interview with authors of Hip Fracture reviews

 

Commentary on Twitter

 


Systematic Review: There is insufficient evidence to recommend the use of any medicines to prevent post‐traumatic stress disorder in people exposed to a traumatic event.

16 Feb, 2022 | 08:46h | UTC

Early pharmacological interventions for universal prevention of post‐traumatic stress disorder (PTSD) – Cochrane Library

Summary: Medicines for preventing post-traumatic stress disorder (PTSD) – Cochrane Library

 

Commentary on Twitter

 


Digital interventions in mental health: evidence syntheses and economic modelling.

16 Feb, 2022 | 08:21h | UTC

Digital interventions in mental health: evidence syntheses and economic modelling – Health Technology Assessment

 


M-A: In patients undergoing colorectal surgery with pelvic dissection, removing urinary catheters on postoperative days 3–4 may provide a balance, minimizing the risk of urine retention (increased when taken too soon) and urinary tract infections (increased when taken too late).

15 Feb, 2022 | 09:45h | UTC

Timing of urinary catheter removal after colorectal surgery with pelvic dissection: A systematic review and meta-analysis – Annals of Medicine and Surgery

 


M-A: Timing of carotid intervention in symptomatic carotid artery stenosis.

15 Feb, 2022 | 08:51h | UTC

Timing of Carotid Intervention in Symptomatic Carotid Artery Stenosis: A Systematic Review and Meta-Analysis – European Journal of Vascular & Endovascular Surgery

 


Systematic Review: Arthroplasties for hip fracture in adults.

15 Feb, 2022 | 08:41h | UTC

Arthroplasties for hip fracture in adults – Cochrane Library

Summary: Hip replacement surgery in adults – Cochrane Library

Author Interview: Interview with authors of Hip Fracture reviews  – Cochrane Library

 


M-A: Single antiplatelet therapy should be used after transcatheter aortic valve implantation in patients without indication for anticoagulation.

15 Feb, 2022 | 08:32h | UTC

Comparing Single- and Dual-Antiplatelet Therapies After Transcatheter Aortic Valve Implantation – The Annals of Thoracic Surgery (link to abstract – $ for full-text)

Related:

M-A: Aspirin alone better than dual antiplatelet therapy after transcatheter aortic valve implantation

#ESCCongress – [Abstract Only] Randomized trial: aspirin with or without clopidogrel after transcatheter aortic-valve implantation

#ACC21 – [Not published yet] RCT: Among patients undergoing TAVR, full-dose apixaban is not superior to standard of care (vitamin K antagonist if indication for oral anticoagulation; antiplatelet therapy if no indication).

#AHA19 – [Abstract Only] Randomized Trial: An Antiplatelet-based Strategy is Associated with Better Outcomes vs. Anticoagulation After Transcatheter Aortic-Valve Replacement

 


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