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Systematic Reviews & Meta-analysis

Study Commentary: Telemental health is promising as an effective and engaging alternative for in-person therapy.

11 Mar, 2022 | 09:26h | UTC

Telemental health is promising as an effective and engaging alternative for in-person therapy #TeleMentalHealth – The Mental Elf

Original Study: Implementation of Telemental Health Services Before COVID-19: Rapid Umbrella Review of Systematic Reviews – Journal of Medical Internet Research

 


RCT: In patients with low-risk thyroid cancer, thyroidectomy without ablation radioiodine was noninferior to thyroidectomy with ablation radioiodine at 3 years.

10 Mar, 2022 | 10:59h | UTC

Thyroidectomy without Radioiodine in Patients with Low-Risk Thyroid Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: New research casts doubt on a cornerstone of thyroid cancer treatment – STAT

 

Commentary on Twitter

 


Meta-analysis of randomized trials: benefits and harms of direct oral anticoagulation and low molecular weight heparin for thromboprophylaxis in patients undergoing non-cardiac surgery.

10 Mar, 2022 | 10:48h | UTC

Benefits and harms of direct oral anticoagulation and low molecular weight heparin for thromboprophylaxis in patients undergoing non-cardiac surgery: systematic review and network meta-analysis of randomised trials – The BMJ

 

Commentary on Twitter

 


M-A: Comparative efficacy and tolerability of 32 oral and long-acting injectable antipsychotics for the maintenance treatment of adults with schizophrenia.

10 Mar, 2022 | 10:54h | UTC

Comparative efficacy and tolerability of 32 oral and long-acting injectable antipsychotics for the maintenance treatment of adults with schizophrenia: a systematic review and network meta-analysis – The Lancet (link to abstract – $ for full-text)

 


Systematic Review: Pharmacotherapy for post-traumatic stress disorder.

10 Mar, 2022 | 10:30h | UTC

Pharmacotherapy for post traumatic stress disorder (PTSD) – Cochrane Library

 


M-A: Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia.

9 Mar, 2022 | 08:38h | UTC

Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Degree of myopia and glaucoma risk: a dose-response meta-analysis.

8 Mar, 2022 | 08:32h | UTC

Degree of Myopia and Glaucoma Risk: A Dose-Response Meta-analysis – American Journal of Ophthalmology

 


M-A: Site-specific therapy in cancers of unknown primary site.

8 Mar, 2022 | 08:23h | UTC

Site-specific therapy in cancers of unknown primary site: a systematic review and meta-analysis – ESMO Open

 


Systematic Review: Diagnostic test accuracy and cost‐effectiveness of tests for codeletion of chromosomal arms 1p and 19q in people with glioma.

8 Mar, 2022 | 08:24h | UTC

Diagnostic test accuracy and cost‐effectiveness of tests for codeletion of chromosomal arms 1p and 19q in people with glioma – Cochrane Library

 


Systematic Review: Anticoagulants for people hospitalized with COVID‐19.

7 Mar, 2022 | 00:48h | UTC

Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library

Summary: Do blood thinners prevent people who are hospitalised with COVID-19 from developing blood clots? – Cochrane Library

Related: Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week.

 


M-A: Clinical characteristics, surveillance, treatment allocation, and outcomes of non-alcoholic fatty liver disease-related hepatocellular carcinoma.

7 Mar, 2022 | 00:07h | UTC

Clinical characteristics, surveillance, treatment allocation, and outcomes of non-alcoholic fatty liver disease-related hepatocellular carcinoma: a systematic review and meta-analysis – The Lancet Oncology

 

Commentary from the author on Twitter (thread – click for more)

 


Systematic Review: Proton pump inhibitor treatment initiated prior to endoscopic diagnosis in upper gastrointestinal bleeding.

6 Mar, 2022 | 23:41h | UTC

Proton pump inhibitor treatment initiated prior to endoscopic diagnosis in upper gastrointestinal bleeding – Cochrane Library

Commentary: Pre-Endoscopic Proton Pump Inhibitor Use May Decrease Risk for Endoscopic Hemostatic Treatment – Gastroenterology Advisor

 


Systematic Review: Routine vaginal examinations compared to other methods for assessing progress of labor to improve outcomes for women and babies at term.

6 Mar, 2022 | 23:44h | UTC

Routine vaginal examinations compared to other methods for assessing progress of labour to improve outcomes for women and babies at term – Cochrane Library

Summary: Routine vaginal examinations in labour – Cochrane Library

 


Systematic Review: Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis.

4 Mar, 2022 | 08:46h | UTC

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis – Cochrane Library

Summary: What are the benefits and risks of topical medications for treating epidemic keratoconjunctivitis? – Cochrane Library

 


Systematic Review: Interventions for minimal change disease in adults with nephrotic syndrome.

4 Mar, 2022 | 08:47h | UTC

Interventions for minimal change disease in adults with nephrotic syndrome – Cochrane Library

Commentary: Interventions for minimal change disease in adults with nephrotic syndrome – Cochrane Library

 


Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts.

4 Mar, 2022 | 08:45h | UTC

Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts – The Lancet Public Health

Commentaries:

Meta-analysis of 15 studies reports new findings on how many daily walking steps needed for longevity benefit – University of Massachusetts Amherst

Living a long life is a multi-step process – The Lancet Public Health

 


M-A: Use of tocilizumab and sarilumab alone or in combination with corticosteroids for covid-19.

3 Mar, 2022 | 08:49h | UTC

Use of tocilizumab and sarilumab alone or in combination with corticosteroids for covid-19: systematic review and network meta-analysis – BMJ Medicine

Editorial: Treatment of severe covid-19 with interleukin 6 receptor inhibition – BMJ Medicine

Related study (just published): Mortality Rates Among Hospitalized Patients With COVID-19 Infection Treated With Tocilizumab and Corticosteroids: A Bayesian Reanalysis of a Previous Meta-analysis – JAMA Network Open

 


The effects of foods on LDL cholesterol levels: A systematic review of the accumulated evidence from systematic reviews and meta-analyses of randomized controlled trials.

3 Mar, 2022 | 08:22h | UTC

The effects of foods on LDL cholesterol levels: A systematic review of the accumulated evidence from systematic reviews and meta-analyses of randomized controlled trials – Nutrition, Metabolism & Cardiovascular Diseases

 


Meta-analysis showed a 2.4-fold increased risk of cancer in patients with pediatric-onset inflammatory bowel disease.

3 Mar, 2022 | 08:06h | UTC

Development of Cancer Among Patients With Pediatric-Onset Inflammatory Bowel Disease: A Meta-analysis of Population-Based Studies – JAMA Network Open

Commentary: Kids With IBD Need Close Monitoring as They Grow Up — Meta-analysis confirms: substantially increased cancer risk in adulthood – MedPage Today (free registration required)

 


M-A: Association of tranexamic acid administration with mortality and thromboembolic events in patients with traumatic injury.

3 Mar, 2022 | 07:57h | UTC

Association of Tranexamic Acid Administration With Mortality and Thromboembolic Events in Patients With Traumatic Injury: A Systematic Review and Meta-analysis – JAMA Network Open

Related:

M-A: Prehospital Tranexamic Acid reduces mortality among bleeding trauma patients without increasing the risk of venous thromboembolism.

Tranexamic acid after traumatic brain injury: Exploratory analysis combining data from CRASH-2 and CRASH-3 trials suggests reduced mortality

Meta-analysis: Efficacy and safety of tranexamic acid in acute traumatic brain injury

Randomized trial: Tranexamic acid during prehospital transport in patients at risk for hemorrhage after injury

Randomized trial: Out-of-hospital tranexamic acid does not improve neurologic outcomes in patients with traumatic brain injury

Editorial: Is Tranexamic Acid Going to CRASH the Management of Traumatic Brain Injury?

Practice-Changing: Tranexamic Acid Reduces the Risk of Head Injury-related Death in Patients with Mild-to-moderate Head Injury

 


M-A: Evaluation of budesonide-formoterol for maintenance and reliever therapy among patients with poorly controlled asthma.

3 Mar, 2022 | 07:59h | UTC

Evaluation of Budesonide-Formoterol for Maintenance and Reliever Therapy Among Patients With Poorly Controlled Asthma: A Systematic Review and Meta-analysis – JAMA Network Open

 


Systematic Review: Postcholecystectomy diarrhea rate and predictive factors.

2 Mar, 2022 | 08:48h | UTC

Postcholecystectomy diarrhoea rate and predictive factors: a systematic review of the literature – BMJ Open

 


M-A: Survival for waitlisted kidney failure patients receiving transplantation vs. remaining on waiting list.

2 Mar, 2022 | 08:46h | UTC

Survival for waitlisted kidney failure patients receiving transplantation versus remaining on waiting list: systematic review and meta-analysis – The BMJ

 


Guideline: Plasma exchange and glucocorticoid dosing for patients with ANCA-associated vasculitis.

27 Feb, 2022 | 22:40h | UTC

Plasma exchange and glucocorticoid dosing for patients with ANCA-associated vasculitis: a clinical practice guideline – The BMJ

See also: The effects of plasma exchange in patients with ANCA-associated vasculitis: an updated systematic review and meta-analysis – The BMJ

 

Commentary on Twitter

 


Meta-analysis of randomized trials: Effectiveness of physical activity interventions delivered or prompted by health professionals in primary care settings.

25 Feb, 2022 | 11:27h | UTC

Effectiveness of physical activity interventions delivered or prompted by health professionals in primary care settings: systematic review and meta-analysis of randomised controlled trials – The BMJ

Editorial: Lack of physical activity is a global problem

News Release: Primary care exercise interventions help boost physical activity levels and reduce weight in adults – BMJ

 


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