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Systematic Reviews & Meta-analysis

M-A: Efficacy of interventions to reduce long term opioid treatment for chronic non-cancer pain.

5 Apr, 2022 | 08:29h | UTC

Efficacy of interventions to reduce long term opioid treatment for chronic non-cancer pain: systematic review and meta-analysis – The BMJ

 


Systematic Review: Prostatic arterial embolization for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia.

5 Apr, 2022 | 08:10h | UTC

Prostatic arterial embolization for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia – Cochrane Library

Summary: Prostatic arterial embolization for treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia – Cochrane Library

 


Systematic Review: Endovascular vs. conventional open surgical repair for thoracoabdominal aortic aneurysms.

5 Apr, 2022 | 08:11h | UTC

Endovascular versus conventional open surgical repair for thoracoabdominal aortic aneurysms – Cochrane Library

Summary: Are patient outcomes superior after endovascular or open surgical repair of thoracoabdominal aortic aneurysms? – Cochrane Library

 

Commentary on Twitter

 


Systematic Review: Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open long bone fractures of the upper and lower limbs.

5 Apr, 2022 | 08:08h | UTC

Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open long bone fractures of the upper and lower limbs – Cochrane Library

Summary: The timing of treatment for broken bones in the legs and arms that also have open wounds – Cochrane Library

 


M-A of randomized trials: Effects of capecitabine as part of neo-/adjuvant chemotherapy in patients with breast cancer.

5 Apr, 2022 | 08:06h | UTC

Effects of capecitabine as part of neo-/adjuvant chemotherapy – A meta-analysis of individual breast cancer patient data from 13 randomised trials including 15,993 patients – European Journal of Cancer (link to abstract – $ for full-text)

 


Systematic review: there is insufficient evidence that therapeutic drug monitoring improves outcomes during treatment with penicillins.

4 Apr, 2022 | 00:47h | UTC

A systematic review of the effect of therapeutic drug monitoring on patient health outcomes during treatment with penicillins – Journal of Antimicrobial Chemotherapy

 


M-A: Global estimates of diabetic retinopathy prevalence and progression in pregnant women with preexisting diabetes.

4 Apr, 2022 | 00:42h | UTC

Global Estimates of Diabetic Retinopathy Prevalence and Progression in Pregnant Women With Preexisting Diabetes: A Systematic Review and Meta-analysis – JAMA Ophthalmology (free for a limited period)

Invited Commentary: Diabetic Retinopathy in Pregnancy – JAMA Ophthalmology (free for a limited period)

 

Commentary on Twitter

 


Systematic Review: There is insufficient evidence to support or refute the use of antibiotics for preventing infection following surgery to treat stress urinary incontinence in women.

4 Apr, 2022 | 00:26h | UTC

Prophylactic antibiotics for preventing infection after continence surgery in women with stress urinary incontinence – Cochrane Library

Summary: Antibiotics for preventing infection following surgery to treat stress urinary incontinence in women – Cochrane Library

 

Commentary on Twitter

https://twitter.com/C_Incontinence/status/1509106659842564098

 


RCT: Spectacle lenses with aspherical lenslets for myopia control vs. single-vision spectacle lenses.

4 Apr, 2022 | 00:41h | UTC

Spectacle Lenses With Aspherical Lenslets for Myopia Control vs Single-Vision Spectacle Lenses: A Randomized Clinical Trial – JAMA Ophthalmology

Invited Commentary: Clinical Relevance of Myopia Control With Specialized Spectacles – JAMA Ophthalmology (free for a limited period)

 

Commentary on Twitter

 


Systematic Review | Guidewire or contrast: which works better to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis?

4 Apr, 2022 | 00:28h | UTC

Summary: Guidewire or contrast: which works better for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis? – Cochrane Library

Original Study: Guidewire‐assisted cannulation of the common bile duct for the prevention of post‐endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis – Cochrane Library

 


Network M-A: Prophylactic cyclo‐oxygenase inhibitor drugs to prevent morbidity and mortality in preterm infants.

4 Apr, 2022 | 00:24h | UTC

Prophylactic cyclo‐oxygenase inhibitor drugs for the prevention of morbidity and mortality in preterm infants: a network meta‐analysis – Cochrane Library

Summary: Prophylactic cyclo-oxygenase inhibitor drugs to prevent morbidity and mortality in preterm infants – Cochrane Library

 


Systematic Review: Does giving money to people, in low- and middle-income countries, without conditions attached lead to better health and other life improvements?

1 Apr, 2022 | 10:05h | UTC

Summary: Does giving money to people, in low- and middle-income countries, without conditions attached lead to better health and other life improvements? – Cochrane Library

Original Study: Unconditional cash transfers for reducing poverty and vulnerabilities: effect on use of health services and health outcomes in low‐ and middle‐income countries – Cochrane Library

 


Strengthening systematic reviews in public health: guidance in the Cochrane Handbook for Systematic Reviews of Interventions, 2nd edition.

1 Apr, 2022 | 08:43h | UTC

Strengthening systematic reviews in public health: guidance in the Cochrane Handbook for Systematic Reviews of Interventions, 2nd edition – Journal of Public Health

 


Meta-analysis of randomized trials: Clopidogrel is better than aspirin for the secondary prevention of cardiovascular events.

31 Mar, 2022 | 08:31h | UTC

P2Y12 Inhibitor versus Aspirin Monotherapy for Secondary Prevention of Cardiovascular Events: Meta-Analysis of Randomized Trials – European Heart Journal Open

Commentary: Clopidogrel Superior to ‘Divine’ Aspirin Monotherapy in Secondary Prevention – TCTMD

 

Commentary on Twitter

 


M-A: Psychological interventions for chronic, non-specific low back pain.

31 Mar, 2022 | 08:20h | UTC

Psychological interventions for chronic, non-specific low back pain: systematic review with network meta-analysis – The BMJ

News Release: Study sheds light on psychological therapies for chronic low back pain – British Medical Journal

 


Systematic Review: Evidence-based efficacy of methotrexate in adult Crohn’s disease in different intestinal and extraintestinal indications.

31 Mar, 2022 | 07:50h | UTC

Evidence-based efficacy of methotrexate in adult Crohn’s disease in different intestinal and extraintestinal indications – Therapeutic Advances in Gastroenterology

 


Systematic Review: Interventions for reducing inflammation in familial Mediterranean fever.

30 Mar, 2022 | 10:13h | UTC

Interventions for reducing inflammation in familial Mediterranean fever – Cochrane Library

Summary: Medicines for reducing inflammation in people with familial Mediterranean fever – Cochrane Library

 


Systematic Review: Pregabalin add‐on for drug‐resistant focal epilepsy.

30 Mar, 2022 | 10:10h | UTC

Pregabalin add‐on for drug‐resistant focal epilepsy – Cochrane Library

Summary: Pregabalin add-on for drug-resistant focal epilepsy – Cochrane Library

 


M-A: Effectiveness of cognitive–behavioral therapies of varying complexity in reducing depression in adults.

30 Mar, 2022 | 09:46h | UTC

Effectiveness of cognitive–behavioural therapies of varying complexity in reducing depression in adults: systematic review and network meta-analysis – British Journal of Psychiatry (link to abstract – $ for full-text)

News Release: Enhanced CBT can radically reduce long-term depression, finds study – University of Manchester

 


Meta-analysis of randomized trials: GLP1 receptor agonists increase the risk of gallbladder and biliary diseases (RR, 1.37; 95% CI, 1.23-1.52).

29 Mar, 2022 | 10:02h | UTC

Association of Glucagon-Like Peptide-1 Receptor Agonist Use With Risk of Gallbladder and Biliary Diseases: A Systematic Review and Meta-analysis of Randomized Clinical Trials – JAMA Internal Medicine (free for a limited period)

Commentary: GLP-1 Receptor Agonists: How Safe Are They for the Gallbladder?— Link with gallbladder, biliary diseases could be due to weight loss associated with class of drug – MedPage Today (free registration required)

 


Systematic Review: Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with unknown HIV status.

28 Mar, 2022 | 08:54h | UTC

Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with unknown HIV status – Cochrane Library

Summary: How accurate are asking about symptoms and doing a chest X-ray to screen for tuberculosis of the lungs among adults who are HIV-negative or with unknown HIV status? – Cochrane Library

 


Targeted systemic therapies for psoriatic arthritis: a systematic review and comparative synthesis of short-term articular, dermatological, enthesitis and dactylitis outcomes.

28 Mar, 2022 | 08:28h | UTC

Targeted systemic therapies for psoriatic arthritis: a systematic review and comparative synthesis of short-term articular, dermatological, enthesitis and dactylitis outcomes – RMD Open

 


Weight maintenance after dietary weight loss: systematic review and meta-analysis on the effectiveness of behavioral interventions.

25 Mar, 2022 | 08:41h | UTC

Weight Maintenance after Dietary Weight Loss: Systematic Review and Meta-Analysis on the Effectiveness of Behavioural Intensive Intervention – Nutrients

 


M-A: The impact of cold ischemia time on outcomes of living donor kidney transplantation.

24 Mar, 2022 | 08:33h | UTC

The Impact of Cold Ischaemia Time on Outcomes of Living Donor Kidney Transplantation: A Systematic Review and Meta-Analysis – Journal of Clinical Medicine

 


Systematic Review: Duct‐to‐mucosa vs. other types of pancreaticojejunostomy for the prevention of postoperative pancreatic fistula following pancreaticoduodenectomy.

24 Mar, 2022 | 08:27h | UTC

Duct‐to‐mucosa versus other types of pancreaticojejunostomy for the prevention of postoperative pancreatic fistula following pancreaticoduodenectomy – Cochrane Library

Summary: Is attachment of the excretory duct of the pancreas to the second part of the small intestine better than other reconstruction methods to reduce leakage of juice from the pancreas to the abdominal tissues? – Cochrane Library

 


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