Pharmacology/Pharmaceutical Industry
5 things to know about a COVID vaccine: It won’t be a ‘magic wand’
8 Oct, 2020 | 09:05h | UTC5 Things to Know About a COVID Vaccine: It Won’t Be a ‘Magic Wand’ – Kaiser Health News
[Abstract Only] Interferon Beta-1b and Lopinavir–Ritonavir for Middle East Respiratory Syndrome
8 Oct, 2020 | 08:59h | UTCInterferon Beta-1b and Lopinavir–Ritonavir for Middle East Respiratory Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)
Meta-analysis: Association of SGLT2 inhibitors with cardiovascular and kidney outcomes in patients with Type 2 diabetes
8 Oct, 2020 | 08:57h | UTC
Randomized trial: Lopinavir–ritonavir not beneficial for patients admitted to hospital with COVID-19
7 Oct, 2020 | 08:50h | UTCCommentaries: Study: HIV drug of no benefit to hospitalized COVID patients – CIDRAP AND Antiviral monotherapy for hospitalised patients with COVID-19 is not enough – The Lancet AND
Commentary on Twitter
NEW—Lopinavir-ritonavir is not an effective treatment for patients hospitalised with #COVID19: finding from RECOVERY, randomised, controlled, open-label, platform trial https://t.co/RpiUAvWF1I pic.twitter.com/uI3yiQbEgK
— The Lancet (@TheLancet) October 6, 2020
ACEP Clinical Policy: Critical issues related to opioids in adult patients presenting to the emergency department
8 Oct, 2020 | 08:53h | UTCCommentary: ACEP Opioid Policy Statement – Journal Feed
ACP Guidance: Should Remdesivir be used for the treatment of patients with COVID-19?
7 Oct, 2020 | 09:21h | UTCSystematic review: Remdesivir for Adults With COVID-19: A Living Systematic Review for an American College of Physicians Practice Points – Annals of Internal Medicine
Randomized trial: Tranexamic acid during prehospital transport in patients at risk for hemorrhage after injury
7 Oct, 2020 | 09:04h | UTCCommentaries: Prehospital Tranexamic Acid: STAAMP of Approval or Return to Sender? – JAMA Surgery AND Trial examines prehospital administration of blood-clotting agent in severely injured trauma patients – News Medical
Commentary on Twitter
TXA as an adjunct to prehospital #injury management seems to improve #outcome but only in specific subgroups. A nicely done multicenter trial that raises more questions to be answered. @SCCM @JAMASurgery https://t.co/rTQz8qJO0o
— Lauren R. Sorce, PhD, RN, CPNP-AC/PC, FAAN, FCCM (@SCCMPresident) October 5, 2020
Cohort study: Risk for serious infection with low-dose glucocorticoids in patients with rheumatoid arthritis
7 Oct, 2020 | 08:53h | UTCCommentaries: Glucocorticoids associated with increased risk for infection, even at low doses – American College of Physicians AND Even low-dose glucocorticoids raise serious infection risk in RA patients – medwire News
Commentary on Twitter
ICYMI: #Glucocorticoids are associated with an increased risk for infection, even at doses as low as 5mg or less per day https://t.co/pm9Q72mvhT. pic.twitter.com/rM7GdHkbwW
— Annals of Int Med (@AnnalsofIM) September 24, 2020
[Abstract Only] Once-weekly insulin for Type 2 diabetes without previous insulin treatment
7 Oct, 2020 | 08:54h | UTCOnce-Weekly Insulin for Type 2 Diabetes without Previous Insulin Treatment – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Once-weekly insulin had similar effects to daily insulin in type 2 diabetes, industry-funded trial finds – ACP Internist AND Once-Weekly Insulin Shows Promise in Type 2 Diabetes – NEJM Journal Watch
Systematic review: Sublingual immunotherapy for asthma
6 Oct, 2020 | 00:11h | UTCSublingual immunotherapy for asthma – Cochrane Library
Summary: Sublingual immunotherapy for asthma – Cochrane Library
Video: Who gets coronavirus vaccine first?
4 Oct, 2020 | 23:33h | UTCWho Gets Coronavirus Vaccine First? – JAMA
Framework for equitable allocation of COVID-19 vaccine
4 Oct, 2020 | 23:34h | UTCRelated: WHO SAGE values framework for the allocation and prioritization of COVID-19 vaccination – World Health Organization AND An ethical framework for global vaccine allocation – Science AND US Adults’ Preferences for Public Allocation of a Vaccine for Coronavirus Disease 2019 – JAMA Network Open
Perspective: What we know about vitamin D and Covid-19 (spoiler: not much)
4 Oct, 2020 | 23:28h | UTCWhat We Know About Vitamin D and Covid-19 – Medium
Systematic review: It is unlikely that magnesium improves skeletal muscle cramps in older adults
4 Oct, 2020 | 22:48h | UTCMagnesium for skeletal muscle cramps – Cochrane Library
Ensuring uptake of vaccines against SARS-CoV-2
2 Oct, 2020 | 09:27h | UTCEnsuring Uptake of Vaccines against SARS-CoV-2 – New England Journal of Medicine
What does it mean if a vaccine is ‘successful’?
2 Oct, 2020 | 09:25h | UTCWhat Does It Mean If a Vaccine Is ‘Successful’? – Wired
‘Provocative results’ boost hopes of antibody treatment for COVID-19
2 Oct, 2020 | 09:21h | UTC‘Provocative results’ boost hopes of antibody treatment for COVID-19 – Science
Medication related hospital admissions and readmissions in older patients: an overview of literature
2 Oct, 2020 | 09:15h | UTC
Drug-related orthostatic hypotension: Beyond anti-hypertensive medications
2 Oct, 2020 | 09:13h | UTCDrug-Related Orthostatic Hypotension: Beyond Anti-Hypertensive Medications – Drugs & Aging
Commentary on Twitter
Drug-Related Orthostatic Hypotension: Beyond Anti-Hypertensive Medications. An open access review … https://t.co/YB0KiEiAtF pic.twitter.com/YzfsmQmtbZ
— Rohan Elliott (@elliott_rohan) September 30, 2020
Randomized trial: Hydroxychloroquine vs. placebo for pre-exposure SARS-CoV-2 prophylaxis among health care workers
1 Oct, 2020 | 09:17h | UTCCommentary: Hydroxychloroquine didn’t prevent COVID-19 among health care workers in new study – CNN
Commentary on Twitter
#Hydroxychloroquine taken daily by hospital-based health care providers over 8 weeks did not prevent #SARSCoV2 infection, in a double-blind randomized placebo-controlled trial performed at 2 University of Pennsylvania hospitals https://t.co/7XHn6uBh4Z
— JAMA Internal Medicine (@JAMAInternalMed) September 30, 2020
Recommendations for antibacterial therapy in adults with COVID-19 – An evidence based guideline
1 Oct, 2020 | 09:15h | UTC
Commentary on Twitter
🔥Just published🔥@CMIJournal
Recommendations for antibacterial therapy in adults with COVID-19 – An evidence based guideline by the Dutch Working Party on Antibiotic Policy. #IDTwitter #COVID19 https://t.co/7cfZtS6Duv pic.twitter.com/Kz7CPMNLmh— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) September 30, 2020
[Abstract Only] Atezolizumab for first-line treatment of PD-L1–selected patients with non–small-cell lung cancer
1 Oct, 2020 | 08:53h | UTCCommentary: Atezolizumab Leads to Longer OS for Some Types of Advanced NSCLC, Study Says – AJMC
[Abstract Only] Nationwide cohort study in Sweden shows HPV vaccination linked to reduced risk of invasive cervical cancer
1 Oct, 2020 | 08:56h | UTCHPV Vaccination and the Risk of Invasive Cervical Cancer – New England Journal of Medicine
News Release: HPV vaccine effective against cervical cancer – Karolinska Institutet
Investigational COVID-19 vaccine well-tolerated and generates immune response in older adults
30 Sep, 2020 | 09:36h | UTCOriginal Article: Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults – New England Journal of Medicine
Commentary on Twitter
The Moderna mRNA vaccine, which elicited antibodies and T cells specific for the Covid-19 virus in adults 55 years of age or younger, elicited similarly high levels of neutralizing-antibody and CD4 T-cell responses in older adults. #COVID19 #SARSCoV2
— NEJM (@NEJM) September 29, 2020
Editorial – Stress ulcer prophylaxis: Is mortality a useful endpoint?
30 Sep, 2020 | 09:31h | UTCStress ulcer prophylaxis: Is mortality a useful endpoint? – Intensive Care Medicine
Commentary on Twitter
Stress ulcer prophylaxis: restrict to highest GI bleeding risk #ICU pts; still uncertainties on harmful effects (ie PK interactions?). Early EN, effective if low-risk + reducing underfeeding, to be encouraged. https://t.co/2EOsefikFc
Referring Wang et al https://t.co/MXnfHYyoJ4 pic.twitter.com/Xz8wmTzn62
— Intensive Care Medicine (@yourICM) September 29, 2020