Pharmacology/Pharmaceutical Industry
WHO publishes pricing policy guideline to improve affordable access to medicines
30 Sep, 2020 | 09:33h | UTCNews release: WHO publishes pricing policy guideline to improve affordable access to medicines – World Health Organization
Original Guideline: WHO guideline on country pharmaceutical pricing policies – World Health Organization
Commentary on Twitter
The 🆕 guideline covers 🔟 pricing policy approaches, incl.:
✔️ External & internal reference pricing
✔️ Value-based pricing
✔️ Promoting price transparency
✔️ Tendering & negotiation
✔️ Pooled procurement
✔️ Cost-plus pricing
…and more👉 https://t.co/XYqUYStolJ pic.twitter.com/T7vDMUmfBK
— World Health Organization (WHO) (@WHO) September 29, 2020
COVID-19 vaccine may not need to be fully effective to benefit public health
29 Sep, 2020 | 10:06h | UTCOriginal Report: Modelling the allocation and impact of a COVID-19 vaccine – Imperial College London
Commentary on Twitter
Even an imperfect, partially effective vaccine against COVID-19 could have a substantial public health benefit if rolled out in 2021
https://t.co/DDkHarm0KS— Imperial School of Public Health (@ImperialSPH) September 28, 2020
Review: SARS-CoV-2 vaccines in development
29 Sep, 2020 | 10:09h | UTCSARS-CoV-2 vaccines in development – Nature
Commentary on Twitter
1) SARS-CoV-2 Vaccines – I promised a Tweetorial and here we go. This is going to be long and nerdy. But I'll make sure it is easy to understand. If you want more details, please just read this: https://t.co/XBnamI2pKk
— Florian Krammer (@florian_krammer) September 28, 2020
A layperson’s guide to how — and when — a Covid-19 vaccine could be authorized
29 Sep, 2020 | 10:07h | UTCA layperson’s guide to how — and when — a Covid-19 vaccine could be authorized – STAT
AHA Scientific Statement: Cardiorenal protection with the newer antidiabetic agents in patients with diabetes and chronic kidney disease
29 Sep, 2020 | 10:00h | UTCNews Release: Newer Type 2 diabetes medications have heart and kidney disease benefits, too – AHA Newsroom
Sophisticated purchasing of pharmaceuticals: Learning from other countries
29 Sep, 2020 | 09:55h | UTCSophisticated Purchasing of Pharmaceuticals: Learning From Other Countries – JAMA
Related: Drug Reimbursement Regulation in 6 Peer Countries – JAMA Internal Medicine (free for a limited period)
Commentary on Twitter
#Governments can do Cost-effective purchasing of #pharmaceuticals if they do unified purchases and leverage on solid #health technology assessment entities. #Knowledge and #synergy are key!#HTA #healthcare #healthcaresystems #healthcaremanagement https://t.co/16GmUCCqSZ
— Vanessa Campo-Ruiz, MD PhD (@VCSTX) September 28, 2020
IDSA updated guidelines on the treatment of patients with COVID-19
28 Sep, 2020 | 01:40h | UTC
Commentary on Twitter
.@IDSAInfo has updated its #COVID19 treatment guidelines:
*Don't give #tocilizumab
*Give #dexamethasone but not if room air oxygen saturation is > 94%https://t.co/66nwQQZgsz pic.twitter.com/PQNAaFBZS4— Mike Stevens (@Dr_Mike_Stevens) September 26, 2020
COVID-vaccine results are on the way — and scientists’ concerns are growing
28 Sep, 2020 | 01:33h | UTCCOVID-vaccine results are on the way — and scientists’ concerns are growing – Nature
Commentary on Twitter
Several ongoing coronavirus-vaccine trials could announce game-changing results next month. Scientists, though, have growing concerns. Here are the three areas they are watching closely. https://t.co/QxyA1zM0rY
— Nature Portfolio (@NaturePortfolio) September 26, 2020
[Abstract Only] Randomized trial tests metformin in women with type 2 diabetes in pregnancy
28 Sep, 2020 | 01:30h | UTCCommentary: Welcome news for pregnant women with type 2 diabetes – MedicalXpress
Commentary on Twitter
https://twitter.com/TIME_research/status/1306856108338933765
Randomized trial: Gabapentin not effective for chronic pelvic pain in women
28 Sep, 2020 | 01:25h | UTCCommentary: Common pelvic pain drug is ineffective, study finds – University of Edinburgh
Commentary on Twitter
1/5 Pleased to announce publication of our @GaPP2_trial in @lancet today – the largest ever study into treatment for female chronic pelvic pain @exppect @MRC_CRH @EdinUniMedicine @EdinUniMedia @NIHRresearch @BhamCTU @GynaeResearcher https://t.co/NYEAxo2VAh https://t.co/A0ZOr8gqc3 pic.twitter.com/zwn8F7KRHO
— Andrew Horne (@horne_research) September 25, 2020
[Abstract Only] Meta-analysis: Direct oral anticoagulants for cancer-associated venous thromboembolism
28 Sep, 2020 | 01:22h | UTC
Perspective: We can’t tackle the pandemic without figuring out which Covid-19 vaccines work the best
25 Sep, 2020 | 02:39h | UTCWe can’t tackle the pandemic without figuring out which Covid-19 vaccines work the best – STAT
Here come the tortoises: In the race for a Covid-19 vaccine, slow starters could still win out
25 Sep, 2020 | 02:38h | UTC
Randomized trial: Dapagliflozin in patients with chronic kidney disease
25 Sep, 2020 | 02:34h | UTCDapagliflozin in Patients with Chronic Kidney Disease – New England Journal of Medicine (free for a limited period)
Commentary: Dapagliflozin Cuts Renal Risks in Patients with CKD, Regardless of Diabetes Status – NEJM Journal Watch
New CDC recommendations for meningococcal vaccination
25 Sep, 2020 | 02:33h | UTC
Evaluating and deploying Covid-19 vaccines — The importance of transparency, scientific integrity, and public trust
24 Sep, 2020 | 09:27h | UTC
How close is a coronavirus vaccine?
24 Sep, 2020 | 09:25h | UTCHow close is a coronavirus vaccine? – Financial Times
Commentary on Twitter
A very good infographic on the #SARSCoV2 vaccineshttps://t.co/iIXQPUEecN @FT via @NChildersMEP
1. What is a Phase 3 trial? Number of events, efficacy pic.twitter.com/tbwtdOOYoB— Eric Topol (@EricTopol) September 24, 2020
Lower-dose zinc for childhood diarrhea — a randomized, multicenter trial
24 Sep, 2020 | 09:21h | UTC
Commentary on Twitter
In this randomized trial involving children in Tanzania and India, 5 mg and 10 mg of daily zinc were noninferior to 20 mg of zinc for diarrhea and resulted in less vomiting.
— NEJM (@NEJM) September 23, 2020
[Preprint] Randomized trial: Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers
23 Sep, 2020 | 14:17h | UTC
Commentary on Twitter
🔥 #Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers: a randomized trial 🔥
-1st RCT on HCQ as PrEP
-1483 HCW randomized to HCQ 1x or 2x weekly or placebo
-No difference in development of confirmed or probable COVID19 https://t.co/Gn1otqKhrW pic.twitter.com/3r0HB56h9y
— Ilan Schwartz is on🦋 (@GermHunterMD) September 21, 2020
COVID-19 clinical trials: Learning from exceptions in the research chaos
23 Sep, 2020 | 14:50h | UTCCOVID-19 clinical trials: learning from exceptions in the research chaos – Nature
Commentary on Twitter
Our analysis on #COVID clinical trials on Nature Medicine. Only big randomised trials can answer rapidly & reliably. Megatrials need support from regulators, funders, health services, docs. Pre-existing trial networks helpful. Collaboration key to success. https://t.co/YlalAEMR9r pic.twitter.com/wElfXfXdol
— Kari Tikkinen (@KariTikkinen) September 22, 2020
USPSTF draft statement: Insufficient evidence to screen for Vitamin D deficiency in asymptomatic adults
23 Sep, 2020 | 14:36h | UTC
NICE Guideline: Antimicrobial prescribing for insect bites and stings
23 Sep, 2020 | 14:40h | UTC
What can we expect from first-generation COVID-19 vaccines?
22 Sep, 2020 | 10:02h | UTCWhat can we expect from first-generation COVID-19 vaccines? – The Lancet
Commentary on Twitter
We need to calibrate our expectations for the 1st generation of #SARSCoV2 vaccines https://t.co/QTJbyOd9xQ @TheLancet by @gmleunghku and Malik Peiris @hkumed Pe-covid normalcy is not near. pic.twitter.com/Y15TqfoRlf
— Eric Topol (@EricTopol) September 21, 2020
Clinical review: Emerging immunotherapies in multiple myeloma
23 Sep, 2020 | 14:33h | UTCEmerging immunotherapies in multiple myeloma – The BMJ
Commentary on Twitter
Despite advances in treatment in the past 20yrs, multiple myeloma remains an incurable disease. This review summarizes the evidence of these various immunotherapies, their mechanism of action, and data on treatments' safety and efficacy #BMJEducation https://t.co/JWeMlJ89YR
— The BMJ (@bmj_latest) September 22, 2020
‘Landmark moment’: 156 countries agree to Covid vaccine allocation deal
22 Sep, 2020 | 09:45h | UTC‘Landmark moment’: 156 countries agree to Covid vaccine allocation deal – The Guardian