Pharmacology/Pharmaceutical Industry
WHO unveils global plan to fairly distribute COVID-19 vaccine, but challenges await
22 Sep, 2020 | 09:47h | UTCWHO unveils global plan to fairly distribute COVID-19 vaccine, but challenges await – Science
How bad has the pandemic been for childhood vaccinations?
22 Sep, 2020 | 09:41h | UTCHow Bad Has The Pandemic Been For Childhood Vaccinations? – NPR
To find a vaccine for COVID-19, will we have to deliberately infect people?
22 Sep, 2020 | 09:40h | UTCTo find a vaccine for COVID-19, will we have to deliberately infect people? – National Geographic
Guideline: Management of dyslipidemia for cardiovascular disease risk reduction
22 Sep, 2020 | 09:33h | UTCSummary: VA/DoD Guidelines on Dyslipidemia Recommend Against Frequent LDL Testing – NEJM Journal Watch
Commentary on Twitter
https://twitter.com/ATallantMD/status/1308199038513278978
Review: Artificial intelligence in COVID-19 drug repurposing
22 Sep, 2020 | 09:36h | UTCArtificial intelligence in COVID-19 drug repurposing – The Lancet Digital Health
Clinical update: Hormonal contraception in women with hypertension
22 Sep, 2020 | 09:32h | UTCHormonal Contraception in Women With Hypertension – JAMA (free for a limited period)
Commentary on Twitter
https://twitter.com/JAMA_current/status/1308088618846691330
[Preprint] Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19: An international collaborative meta-analysis of randomized trials
20 Sep, 2020 | 21:42h | UTC
Commentary on Twitter
This meta-analysis of 7,913 patients from 26 RCTs (16 unpublished) found no mortality benefit to #hydroxychloroquine or chloroquine in COVID19
Combined summary OR for all-cause mortality for HCQ 1.08, 95%CI 0.99-1.18
Confirms HCQ does not help, may harmhttps://t.co/4o9bXkOo5Q pic.twitter.com/QG1XMzN0da
— Ilan Schwartz is on🦋 (@GermHunterMD) September 19, 2020
Who gets a COVID vaccine first? Access plans are taking shape
20 Sep, 2020 | 21:24h | UTCWho gets a COVID vaccine first? Access plans are taking shape – Nature
Related: WHO Guidance: Allocation and prioritization of COVID-19 vaccination
Commentary on Twitter
Advisory groups around the world are working out plans for who should get priority access to a #covid19 vaccine: https://t.co/9g67rFJUrT pic.twitter.com/BLhAcKiVCK
— nature (@Nature) September 18, 2020
[Abstract Only] Survival with Olaparib in metastatic castration-resistant prostate cancer
20 Sep, 2020 | 21:13h | UTC
Commentary on Twitter
The PROfound trial showed that olaparib prolonged imaging-based progression-free survival among patients whose tumors contained defects in the BRCA1, BRCA2, or ATM. With longer follow-up, the trial now shows that olaparib prolonged overall survival in these patients. #ESMO20
— NEJM (@NEJM) September 20, 2020
[Abstract Only] Avelumab maintenance therapy for advanced or metastatic urothelial carcinoma
20 Sep, 2020 | 21:11h | UTC
Commentary on Twitter
Maintenance avelumab plus best supportive care significantly prolonged overall survival, as compared with best supportive care alone, among patients with urothelial cancer who had disease that had not progressed with first-line chemotherapy. #ESMO20
— NEJM (@NEJM) September 18, 2020
Two pharma companies released their coronavirus vaccine blueprints in a bid to regain public trust
18 Sep, 2020 | 09:30h | UTC
Study: Longer-than-necessary duration of outpatient antibiotic therapy for common outpatient infections
18 Sep, 2020 | 09:21h | UTC
Commentary on Twitter
NEW #CID using large NDTI dataset,clinicians defaulted 10d courses for most conditions, regardless of guideline-recommendations. Median antibiotic course
duration was 10 days for all conditions except acute cystitis. #IDTwitter https://t.co/WTJBFEcRtk pic.twitter.com/TAx7twUoTo— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) September 16, 2020
WHO Guidance: Allocation and prioritization of COVID-19 vaccination
17 Sep, 2020 | 09:42h | UTCCommentary: World Health Organization announces distribution plan for COVID-19 vaccine – ABD News
Related: An ethical framework for global vaccine allocation – Science
Antimicrobial resistance: The next big pandemic?
18 Sep, 2020 | 09:19h | UTCAntimicrobial resistance: The next big pandemic? – Open Access Government
[Press release – not published yet] Eli Lilly reports first, promising results for an antibody against COVID-19
17 Sep, 2020 | 09:28h | UTCEli Lilly reports first, promising results for an antibody against COVID-19 – Science
Press release: Lilly announces proof of concept data for neutralizing antibody LY-CoV555 in the COVID-19 outpatient setting
[Abstract Only] Two-year, randomized, controlled trial of belimumab in lupus nephritis
17 Sep, 2020 | 09:20h | UTCTwo-Year, Randomized, Controlled Trial of Belimumab in Lupus Nephritis – New England Journal of Medicine (link to abstract – $ for full-text)
Lifelong aspirin for all in the secondary prevention of chronic coronary syndrome: Still sacrosanct or is reappraisal warranted?
17 Sep, 2020 | 09:19h | UTCLifelong Aspirin for All in the Secondary Prevention of Chronic Coronary Syndrome: Still Sacrosanct or is Reappraisal Warranted? – Circulation (free for a limited period)
Perspective: Up is down — pharmaceutical industry caution vs. federal acceleration of Covid-19 vaccine approval
16 Sep, 2020 | 09:06h | UTC
UK tests if COVID-19 vaccines might work better inhaled
16 Sep, 2020 | 08:56h | UTCUK tests if COVID-19 vaccines might work better inhaled – Associated Press
Coronavirus: Monoclonal antibodies to begin UK trial
16 Sep, 2020 | 08:53h | UTCCoronavirus: Monoclonal antibodies to begin UK trial – BBC
See also: Covid-19: RECOVERY trial will evaluate “antiviral antibody cocktail” – The BMJ
AHA Scientific Statement: Drug-induced arrhythmias
16 Sep, 2020 | 08:50h | UTCDrug-Induced Arrhythmias: A Scientific Statement From the American Heart Association – Circulation
Commentary: Drug Proarrhythmia
Top Things to Know: Drug-Induced Arrhythmias
News Release: Identifying, preventing and managing heart rhythm side effects of medicines
NIH launches two trials to test blood thinners in COVID-19 patients
15 Sep, 2020 | 08:56h | UTCNIH launches two trials to test blood thinners in COVID-19 patients – Reuters
Scientists relieved as coronavirus vaccine trial restarts — but question lack of transparency
15 Sep, 2020 | 08:53h | UTC
Coronavirus: Who would get the vaccine first?
15 Sep, 2020 | 08:47h | UTCCoronavirus: Who would get the vaccine first? – BBC
Perspective: Vaccine transparency
15 Sep, 2020 | 08:48h | UTCVaccine Transparency – Science Translational Medicine