Pharmacology/Pharmaceutical Industry
[Abstract Only] Preliminary trial on the effectiveness of Curcuma longa extract for the treatment of knee osteoarthritis
15 Sep, 2020 | 08:38h | UTCCommentaries: Turmeric May Help Relieve Pain from Knee Osteoarthritis – NEJM Journal Watch
Largest global vaccine confidence survey reveals hesitancy hotspots
14 Sep, 2020 | 01:16h | UTCThe Lancet Infographics: How global perceptions of vaccines have changed
Commentary on Twitter
New research mapping global trends in vaccine confidence across 149 countries between 2015-19 & based on data from over 284,000 adults surveyed about their views on whether vaccines are important, safe and effective, reveals vaccine hesitancy hotspots https://t.co/cbgCLEFF0C
— The Lancet (@TheLancet) September 10, 2020
Updated meta-analysis: Drug treatments for Covid-19
14 Sep, 2020 | 01:04h | UTCDrug treatments for covid-19: living systematic review and network meta-analysis – The BMJ
Commentary on Twitter
https://twitter.com/RSiemieniuk/status/1304447644438327297
AstraZeneca resumes Covid-19 vaccine trials in the U.K.
14 Sep, 2020 | 01:01h | UTCAstraZeneca resumes Covid-19 vaccine trials in the U.K. – STAT
See also: The ethics of pausing a vaccine trial in the midst of a pandemic: a conversation with Ruth Faden – STAT AND University of Oxford resumes vaccine trial
A COVID-19 vaccine may be only 50% effective. Is that good enough?
14 Sep, 2020 | 01:03h | UTCA COVID-19 Vaccine May Be Only 50% Effective. Is That Good Enough? – NPR
[Abstract Only] Randomized trial: Valaciclovir to prevent vertical transmission of cytomegalovirus after maternal primary infection during pregnancy
14 Sep, 2020 | 00:58h | UTC
NSAIDs like ibuprofen not tied to severe COVID-19, death
11 Sep, 2020 | 01:42h | UTCNSAIDs like ibuprofen not tied to severe COVID-19, death – CIDRAP
Editorial: Reassuring the public and clinical community about the scientific review and approval of a COVID-19 vaccine
11 Sep, 2020 | 01:33h | UTC
Preliminary randomized trial evaluated recombinant human granulocyte colony–stimulating factor for patients with COVID-19 and lymphopenia
11 Sep, 2020 | 01:36h | UTCInvited Commentary: Immune Stimulation With Recombinant Human Granulocyte Colony–Stimulating Factor for Coronavirus Disease 2019 (COVID-19)—Beware of Blind Spots
Commentary on Twitter
Preliminary findings from a randomized clinical trial suggest that rhG-CSF treatment should be studied in larger trials and in a broader range of patients with #COVID19 https://t.co/SjsoWOkEXg
— JAMA Internal Medicine (@JAMAInternalMed) September 10, 2020
Perspective: Fairly prioritizing groups for access to COVID-19 vaccines
11 Sep, 2020 | 01:34h | UTCFairly Prioritizing Groups for Access to COVID-19 Vaccines – JAMA
Audio interview: Guidelines for Covid-19 vaccine deployment
11 Sep, 2020 | 01:29h | UTCAudio Interview: Guidelines for Covid-19 Vaccine Deployment – New England Journal of Medicine
The underdog coronavirus vaccines that the world will need if front runners stumble
11 Sep, 2020 | 01:20h | UTCThe underdog coronavirus vaccines that the world will need if front runners stumble – Nature
Opinion: Halting the Oxford vaccine trial doesn’t mean it’s not safe – it shows they’re following the right process
10 Sep, 2020 | 09:42h | UTC
A leading coronavirus vaccine trial is on hold: Scientists react
10 Sep, 2020 | 09:43h | UTCA leading coronavirus vaccine trial is on hold: scientists react – Nature
‘Everyone was left to guess what went wrong’: An open letter to AstraZeneca’s CEO on transparency
10 Sep, 2020 | 09:40h | UTC
Commentary on Twitter
Opinion: "In the middle of a pandemic — when the whole world, literally, is hoping a useful vaccine is on the horizon — everyone was left to guess what went wrong and what it might mean," @Pharmalot writes. https://t.co/jOpMyxC1dQ
— STAT (@statnews) September 9, 2020
[Abstract Only] Randomized trial: Nonmetastatic, castration-resistant prostate cancer and survival with darolutamide
10 Sep, 2020 | 09:33h | UTC
Link between fluoroquinolones, aorta problems may not be as strong as thought
10 Sep, 2020 | 09:31h | UTCLink between fluoroquinolones, aorta problems may not be as strong as thought – CIDRAP
Original Studies: Association of Fluoroquinolones With the Risk of Aortic Aneurysm or Aortic Dissection – JAMA Internal Medicine AND Association of Infections and Use of Fluoroquinolones With the Risk of Aortic Aneurysm or Aortic Dissection
AstraZeneca Covid-19 vaccine study put on hold due to suspected adverse reaction in participant in the U.K.
9 Sep, 2020 | 09:45h | UTC
Commentary on Twitter
BREAKING: AstraZeneca's #Covid19 vaccine trials have been paused as the company investigates a serious adverse event the occurred in the UK. Not clear if the unexplained illness is linked to the vaccine, or what it was. https://t.co/wGqvvXIBTD
— Helen Branswell 🇨🇦 (@HelenBranswell) September 8, 2020
Drug companies seek to reassure the public about Covid-19 vaccine safety
9 Sep, 2020 | 09:43h | UTCSee also: 9 Drugmakers Sign Safety Pledge In Rush To Develop Coronavirus Vaccine – NPR AND U.S., European COVID-19 vaccine developers pledge to uphold testing rigour – Reuters
IDSA Guidance on the treatment of antimicrobial resistant gram-negative infections
9 Sep, 2020 | 09:24h | UTCNews Release: IDSA Releases Guidance On Treatment Of Antimicrobial-Resistant Infections
Commentary on Twitter
The new @IDSAInfo guidance document on the treatment of MDR GN infections is 🔥🔥🔥. This a really practical/pragmatic document and will be of great use to frontline clinicianshttps://t.co/Eoz2vEHppb
— Mike Stevens (@Dr_Mike_Stevens) September 8, 2020
Perspective: “When will WE have a vaccine?” — understanding questions and answers about Covid-19 vaccination
9 Sep, 2020 | 09:37h | UTC
Commentary on Twitter
People inquiring about Covid-19 vaccines often want to know when the public can be confident that available vaccines are safe and effective, when a vaccine will be available to people like them, and when uptake will be high enough to enable a return to prepandemic life. #COVID19
— NEJM (@NEJM) September 8, 2020
Randomized trial: Out-of-hospital tranexamic acid does not improve neurologic outcomes in patients with traumatic brain injury
9 Sep, 2020 | 09:20h | UTCEditorial: Out-of-Hospital Tranexamic Acid for Traumatic Brain Injury
Commentary on Twitter
In this phase II RCT prehospital tranexamic acid, which inhibits breakdown of fibrin clot, did not improve neurologic outcomes at 6 months vs placebo in patients with moderate to severe TBI https://t.co/PHK91YYxK3 @SusanRowellMD
— JAMA (@JAMA_current) September 8, 2020
APA Guideline for the treatment of patients with schizophrenia
9 Sep, 2020 | 09:17h | UTC
#ERScongress – [Abstract Only] Phase 2 trial of the DPP-1 inhibitor Brensocatib in bronchiectasis
9 Sep, 2020 | 09:14h | UTCPhase 2 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis – New England Journal of Medicine
Commentary on Twitter
Original Article: Phase 2 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis (WILLOW Trial) #ERScongress
— NEJM (@NEJM) September 7, 2020
#ERScongress – [Abstract Only] Inhaled Molgramostim therapy in autoimmune pulmonary alveolar proteinosis
9 Sep, 2020 | 09:16h | UTC
Commentary on Twitter
Original Article: Inhaled Molgramostim Therapy in Autoimmune Pulmonary Alveolar Proteinosis (IMPALA Trial) #ERScongress
— NEJM (@NEJM) September 7, 2020