Pediatrics – Critical Care & Emergencies
RCT: In pediatric ICUs, a bundled intervention that emphasized a physiologically focused cardiopulmonary resuscitation training did not improve outcomes in cardiac arrest.
11 Mar, 2022 | 09:37h | UTCEffect of Physiologic Point-of-Care Cardiopulmonary Resuscitation Training on Survival With Favorable Neurologic Outcome in Cardiac Arrest in Pediatric ICUs: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: CPR Intervention Failed to Improve Survival in Kids With Cardiac Arrest — Physiologically focused CPR training did not lead to difference in survival to discharge – MedPage Today (free registration required)
Commentary on Twitter
Among patients in pediatric ICUs, a bundled intervention that emphasized physiologically focused CPR training and structured clinical event debriefing did not significantly improve patient survival to hospital discharge with favorable neurologic outcome. https://t.co/MbmmSM0Xrt
— JAMA (@JAMA_current) March 8, 2022
Extending the reach of antimicrobial stewardship to pediatric patients.
10 Mar, 2022 | 10:12h | UTC
Association of acute respiratory failure in early childhood with long-term neurocognitive outcomes.
9 Mar, 2022 | 08:41h | UTCAssociation of Acute Respiratory Failure in Early Childhood With Long-term Neurocognitive Outcomes – JAMA (link to abstract – $ for full-text)
Commentaries:
IQ Lower for Survivors of PICU Respiratory Failure Hospitalization – HealthDay
FDA issues warning after 2 children strangled by enteral feeding set tubing.
8 Mar, 2022 | 08:33h | UTCFDA issues warning after 2 children strangled by enteral feeding set tubing – AAP News
Original Report: Potential Risk of Strangulation in Children who Use Enteral Feeding Delivery Sets – U.S. Food & Drug Administration
Risk factors for PICU admission and death among children and young people hospitalized with COVID-19 and PIMS-TS in England during the first pandemic year.
17 Feb, 2022 | 09:58h | UTCCommentary: Studies detail risk of severe COVID-19, GI problems in kids – CIDRAP
Commentary on Twitter
The risk of intensive care unit admission among children with COVID-19 is affected by age, ethnicity and comorbidities, according to a @NatureMedicine paper. Understanding these modifiers might help identify at-risk children and guide interventions. https://t.co/MIkLecyNI6 pic.twitter.com/JtN3Ab4Lu7
— Nature Portfolio (@NaturePortfolio) December 20, 2021
ACR Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS–CoV-2 and Hyperinflammation in Pediatric COVID-19.
15 Feb, 2022 | 10:17h | UTCCommentary and summary: ACR Updates Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With COVID – RheumNow
Study identifies risk factors for severe CoviD-19 in children.
15 Feb, 2022 | 10:01h | UTCRisk Factors for Severe COVID-19 in Children – Pediatrics
2022 SCCM Guidelines on prevention and management of pain, agitation, neuromuscular blockade, and delirium in critically ill pediatric patients with consideration of the ICU environment and early mobility.
13 Feb, 2022 | 22:19h | UTC
Commentary on Twitter
New in #PANDEM guidelines for infants & children: guidance on nonpharmacological interventions that can lead to better outcomes:
✅ Music
✅ Physical
✅ Occupational
✅ Child life
What interventions have worked well for you?
Guidelines: https://t.co/lMfFsiEPeV#SCCMSoMe #PedsICU pic.twitter.com/BLksVV0pNo— SCCM (@SCCM) February 4, 2022
Criteria for Pediatric Sepsis—A Systematic Review and Meta-Analysis by the Pediatric Sepsis Definition Taskforce.
8 Feb, 2022 | 08:40h | UTC
Commentary on Twitter
Menon et al: Peds sepsis criteria
???data validation
???? #PedsICU #Sepsis Definition Taskforce?Sys Rev & MA
?106 studies, 81 in MALink: https://t.co/0CdRgwMPcA#CritCareMed @SCCM
Fig: Pooled Mortality rates pic.twitter.com/QcfwmFUylS
— Critical Care Medicine (@CritCareMed) January 1, 2022
In mechanically ventilated pediatric patients, an observational study showed hospitals varied widely in their use of endotracheal aspirates cultures, and higher rates were correlated with increased antibiotic use.
3 Feb, 2022 | 08:19h | UTC
Commentary from the author on Twitter (thread – click for more)
1/ Hey #IDTwitter #LabTwitter @ASCLS @ASMicrobiology , I want to take a moment to break down our new study: Endotracheal Aspirate Culture Variability and Antibiotic Use in Mechanically Ventilated Pediatric Patients https://t.co/SAmD3eY2tB via @JAMANetworkOpen @JAMANetwork
— Andrea Prinzi PhD, MPH,SM(ASCP)?? (@andreaprinzi) December 30, 2021
Systematic Review: Short intravenous antibiotic courses for urinary infections in young infants.
26 Jan, 2022 | 01:24h | UTCShort Intravenous Antibiotic Courses for Urinary Infections in Young Infants: A Systematic Review – Pediatrics (link to abstract – $ for full-text)
RCT: Lidocaine spray may reduce pain during radial arterial puncture.
21 Jan, 2022 | 09:19h | UTCEffectiveness of lidocaine spray on radial arterial puncture pain: A randomized double-blind placebo controlled trial – The American Journal of Emergency Medicine (link to abstract – $ for full-text)
Expert consensus for plasma and platelet transfusion practice in critically ill children.
20 Jan, 2022 | 08:44h | UTC
RCT: In children with community-acquired pneumonia, outpatient antibiotic therapy for 5 days resulted in similar clinical response rates compared to a standard 10-day strategy.
19 Jan, 2022 | 08:39h | UTCShort- vs Standard-Course Outpatient Antibiotic Therapy for Community-Acquired Pneumonia in Children: The SCOUT-CAP Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)
Commentaries:
Trial finds 5 days of antibiotics superior to 10 for kids with pneumonia – CIDRAP
Related:
ACP Guidance: Appropriate Use of Short-Course Antibiotics in Common Infections
RCT: 7 days of antibiotic therapy as good as 14 days for afebrile men with urinary tract infection.
Meta-Analysis: Efficacy of Short-Course Antibiotic Treatments for Community-Acquired Pneumonia
Review: Treatment of multisystem inflammatory syndrome (MIS-C) in children and adolescents.
18 Jan, 2022 | 09:46h | UTCTreatment of MIS-C in Children and Adolescents – Current Pediatrics Reports
Related:
Review of 4,470 cases of Multisystem Inflammatory Syndrome in Children in the US.
An Update on Multisystem Inflammatory Syndrome in Children Related to SARS-CoV-2.
Ten Things to Know About Multisystem Inflammatory Syndrome in Children (MIS-C).
Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison.
Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.
Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children
Cutaneous findings in SARS-CoV-2-associated Multisystem Inflammatory Disease in Children (MIS-C)
SR: Multisystem inflammatory syndrome in children related to COVID-19
RCT: In full-term and near-term neonates, drug treatment of all clinically and electrographically detected seizures was not associated with reduced death rates or disability at 2 years compared with the treatment of only the clinically detected seizures.
13 Jan, 2022 | 08:24h | UTCCommentaries:
Should we treat electrographic seizures? – Neonatal Research
Subclinical Electrographic Seizures in the Newborn—Is More Treatment Better? – JAMA Network Open
Neonatal Seizures: Little Difference Between EEG/Clinical Treatment – Physician’s Weekly
Commentary on Twitter
NEST trial in @JAMANetworkOpen by @rodwhunt explores if treatment of EEG + clinical seizures compared with only treating clinical seizures in encephalopathic infants decreased odds of severe disability at 2 years of age. https://t.co/s3yYi6R3fV #EBNEOalerts #neoEBM #neotwitter pic.twitter.com/xoxVKC2a5z
— Evidence-Based Neo (@EBNEO) December 29, 2021
International study identifies predictors of severe outcomes in children with COVID-19.
12 Jan, 2022 | 09:05h | UTCNews Release: International study identifies predictors of severe outcomes in children with COVID-19 – University of Calgary
Original Study: Outcomes of SARS-CoV-2–Positive Youths Tested in Emergency Departments: The Global PERN–COVID-19 Study – JAMA Network Open
NICE Guideline | Fever in under 5s: assessment and initial management.
17 Dec, 2021 | 08:44h | UTCRelated: AAP Guideline: Evaluation and management of well-appearing febrile infants 8 to 60 days old.
Sepsis in children: state-of-the-art treatment.
16 Dec, 2021 | 08:56h | UTCSepsis in children: state-of-the-art treatment – Therapeutic Advances in Infectious Disease
Antibiotics in critically ill children—a narrative review on different aspects of a rational approach.
16 Dec, 2021 | 08:53h | UTC
Position Paper: Diagnosis, management, and prevention of button battery ingestion in childhood.
15 Dec, 2021 | 08:32h | UTCVisual summary: Diagnosis, Management, and Prevention of Button Battery Ingestion in Childhood
Commentary on Twitter (thread – click for more)
Button battery ingestion in children⚠️: Important? guidelines for diagnosis and management from @ESPGHANSociety #GITwitter https://t.co/TQ1rfjQOpShttps://t.co/fxzzCEl2F2
— ESGE (@ESGE_news) December 14, 2021
RCT: In preterm infants with respiratory distress syndrome, surfactant administration via a thin catheter did not improve outcomes.
15 Dec, 2021 | 08:26h | UTCEffect of Minimally Invasive Surfactant Therapy vs Sham Treatment on Death or Bronchopulmonary Dysplasia in Preterm Infants With Respiratory Distress Syndrome: The OPTIMIST-A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Minimally Invasive Surfactant Therapy to Prevent Bronchopulmonary Dysplasia in Extremely Preterm Infants – JAMA (free for a limited period)
Retrospective study: antimicrobial susceptibility profiles among neonatal early-onset sepsis (EOS) pathogens – “The vast majority of contemporary EOS pathogens are susceptible to the combination of ampicillin and gentamicin”.
14 Dec, 2021 | 08:46h | UTC
Commentary on Twitter
Are bacteria responsible for early-onset sepsis susceptible to empiric antibiotic therapy used in NICU?
A new @NICHD_NIH study by @dus10flan published in @PIDJournal #neoEBM #EBNEOAlertshttps://t.co/6HJf4ZgAGa pic.twitter.com/pGMfbj3DQ6
— Evidence-Based Neo (@EBNEO) December 13, 2021
Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.
7 Dec, 2021 | 10:19h | UTCNews Release: Young people recover quickly from rare myocarditis side effect of COVID-19 vaccine – American Heart Association
Review of 4,470 cases of Multisystem Inflammatory Syndrome in Children in the US.
7 Dec, 2021 | 10:08h | UTCRelated:
An Update on Multisystem Inflammatory Syndrome in Children Related to SARS-CoV-2.
Ten Things to Know About Multisystem Inflammatory Syndrome in Children (MIS-C).
Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison.
Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.
Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children
Cutaneous findings in SARS-CoV-2-associated Multisystem Inflammatory Disease in Children (MIS-C)
SR: Multisystem inflammatory syndrome in children related to COVID-19