Pediatrics – Critical Care & Emergencies | Page 7 of 12 | Links Medicus Content Curation & Alerts in Medicine

The brain in #PICU
?vulnerable brains
?(age-appropriate) tools to assess neuro-function
?latest evidence related to neurocritical care monitoring in #PedsICU
?post discharge: PICS‑p & approaches for neurodevelopmental follow‑up #FOAMcc #FOAMped
? https://t.co/F8c1L7ysPy pic.twitter.com/zsXe3Tv5ns

— Intensive Care Medicine (@yourICM) April 22, 2022

CDC alerts providers to hepatitis cases of unknown origin.

22 Apr, 2022 | 09:34h | UTC

News Release: CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

See Guidance: Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Commentaries:

CDC issues health advisory about acute hepatitis in children – CNN

CDC Issues Alert for Hepatitis in Children With Adenovirus Infection – WebMD

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

Systematic Review: Continuous positive airway pressure (CPAP) for acute bronchiolitis in children.

20 Apr, 2022 | 09:02h | UTC

Continuous positive airway pressure (CPAP) for acute bronchiolitis in children – Cochrane Library

Summary: Continuous positive airway pressure (CPAP) for acute bronchiolitis in children – Cochrane Library

Analysis of an intervention for emergency medical services personnel to reduce epinephrine dosing errors in infants.

19 Apr, 2022 | 01:52h | UTC

Analysis of an Intervention for Emergency Medical Services Personnel to Reduce Epinephrine Dosing Errors in Infants – JAMA Network Open

Commentary on Twitter

In this QI study, an infant resuscitation simulation intervention using 1mL syringes to draw up epinephrine (vs dosing from prefilled 10mL syringes) was associated with increased appropriate epinephrine use & fewer dosage errors, in less time. https://t.co/M3ztB1LMDi

— JAMA Network Open (@JAMANetworkOpen) April 15, 2022

Study showed low rates of severe COVID-19 in children hospitalized with confirmed SARS-CoV-2 infection.

14 Apr, 2022 | 08:49h | UTC

Very low rates of severe COVID-19 in children hospitalised with confirmed SARS-CoV-2 infection in London, England – Journal of Infection

Commentary: Severe COVID-19 extremely rare among children – News Medical

[Preprint] Risk of Hospitalization, severe disease, and mortality due to COVID-19 in children with SARS-CoV-2 infection in Germany – “overall hospitalization rate associated with SARS-CoV-2 infection was 35.9 per 10,000 children, ICU admission rate was 1.7 per 10,000 and case fatality was 0.09 per 10,000”.

Deaths in children and young people in England after SARS-CoV-2 infection during the first pandemic year – “In total, 99.995% of children and young people with a positive SARS-CoV-2 test survived”.

Editorial: COVID-19 vaccines for children – “Although it is true that most children experience asymptomatic or mild disease, some will get quite sick, and a small number will die. It’s why children are vaccinated against influenza, meningitis, chickenpox, and hepatitis”.

COVID-19 disease severity in children infected with the Omicron variant.

Risk factors for PICU admission and death among children and young people hospitalized with COVID-19 and PIMS-TS in England during the first pandemic year.

Study identifies risk factors for severe CoviD-19 in children.

A nationwide cohort study in Denmark showed Long Covid in children is rare and mainly of short duration.

International study identifies predictors of severe outcomes in children with COVID-19.

AHA Scientific Statement: SARS-CoV-2 infection and associated cardiovascular manifestations and complications in children and young adults.

12 Apr, 2022 | 09:59h | UTC

SARS-CoV-2 Infection and Associated Cardiovascular Manifestations and Complications in Children and Young Adults: A Scientific Statement From the American Heart Association – Circulation

News Release: Heart issues after COVID-19 uncommon in children and young adults, more research needed – American Heart Association

Commentary: COVID-19 CV Complications in Children Are Rare, Treatable: AHA Statement – TCTMD

Cohort Study: Predictors of severe illness in children with multisystem inflammatory syndrome after SARS-CoV-2 infection.

12 Apr, 2022 | 09:57h | UTC

Predictors of severe illness in children with multisystem inflammatory syndrome after SARS-CoV-2 infection: a multicentre cohort study – Canadian Medical Association Journal

News Release: Children older than 5 at higher risk of COVID-19-related multisystem inflammatory syndrome – Canadian Medical Association Journal

Commentary: Older Kids More Vulnerable to MIS-C: Study – HealthDay

RCT: In critically ill children requiring noninvasive respiratory support following extubation, high-flow nasal cannula therapy was NOT noninferior to CPAP, resulting in increased time to liberation from respiratory support.

8 Apr, 2022 | 11:07h | UTC

Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Following Extubation on Liberation From Respiratory Support in Critically Ill Children: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Selecting Intermediate Respiratory Support Following Extubation in the Pediatric Intensive Care Unit – JAMA (free for a limited period)

News Release: Trial identifies most effective breathing support for children in intensive care – Imperial College London

Commentary on Twitter

In this study, among critically ill children requiring noninvasive respiratory support following extubation, HFNC vs CPAP failed to meet the criterion for noninferiority for time to liberation from respiratory support. https://t.co/X1lNAO28le #CCR pic.twitter.com/XBnUpsqUNq

— JAMA (@JAMA_current) April 7, 2022

Review: Understanding pediatric ventilation in the operative setting.

6 Apr, 2022 | 08:42h | UTC

Part I: Physical principles of monitoring in the modern anesthesia workstation – Pediatric Anesthesia

Part II: Setting perioperative ventilation – Pediatric Anesthesia

Review: Developmental respiratory physiology.

6 Apr, 2022 | 08:41h | UTC

Developmental respiratory physiology – Pediatric Anesthesia

Update on ventilatory management of extremely preterm infants—A Neonatal Intensive Care Unit perspective.

6 Apr, 2022 | 08:40h | UTC

Update on ventilatory management of extremely preterm infants—A Neonatal Intensive Care Unit perspective – Pediatric Anesthesia

Review: Novel ventilation techniques in children.

6 Apr, 2022 | 08:38h | UTC

Novel ventilation techniques in children – Pediatric Anesthesia

Cluster RCT: Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation.

1 Apr, 2022 | 10:01h | UTC

Abstract: Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation: the SANDWICH cluster stepped-wedge RCT – Health Technology Assessment

Download: Full Report

Development of a consensus-based definition of Focused Assessment with Sonography for Trauma (FAST) in children.

1 Apr, 2022 | 08:35h | UTC

Development of a Consensus-Based Definition of Focused Assessment With Sonography for Trauma in Children – JAMA Network Open

Commentaries:

New FAST Definitions May Improve Trauma Assessment of Children – Medscape (free registration required)

Ultrasonographic views, landmarks, and patient-specific factors to consider in a consensus-based definition of the Focused Assessment With Sonography for Trauma in children with abdominal injury – Physician’s Weekly

Commentary on Twitter

Qualitative study describes the development of an expert definition for high-quality & accurate pediatric Focused Assessment with Sonography for Trauma (FAST), including recommended views, landmarks & imaging quality. @aaronkornblith @nkpluso @pocusnetwork https://t.co/4CTvGp2Rqs

— JAMA Network Open (@JAMANetworkOpen) March 18, 2022

Podcast: Deep dive into deep neck infections in children.

31 Mar, 2022 | 07:57h | UTC

#47: Deep Dive into Deep Neck Infections with Dr. Travis Crook – The Cribsiders

Podcast: Neonatal acute kidney injury pearls.

31 Mar, 2022 | 07:58h | UTC

#46: NephMadness 2022: Neonatal AKI – The Cribsiders

Cohort Study: Short-term outcomes of corticosteroid monotherapy in multisystem inflammatory syndrome in children.

30 Mar, 2022 | 10:40h | UTC

Short-term Outcomes of Corticosteroid Monotherapy in Multisystem Inflammatory Syndrome in Children – JAMA Pediatrics

Commentary on Twitter

In this study, corticosteroid monotherapy successfully treated a subset of patients with mild multisystem inflammatory syndrome in children. https://t.co/fuhHeBSaRp

— JAMA Pediatrics (@JAMAPediatrics) March 28, 2022

RCT: Among premature infants with a gestational age of less than 30 weeks and intubated for at least 7 days at 14 to 28 days, hydrocortisone did not improve survival without bronchopulmonary dysplasia.

24 Mar, 2022 | 09:58h | UTC

Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia – New England Journal of Medicine (link to abstract – $ for full-text)

Rapid point-of-care genotyping to avoid aminoglycoside-induced ototoxicity in neonatal intensive care.

22 Mar, 2022 | 08:01h | UTC

Rapid Point-of-Care Genotyping to Avoid Aminoglycoside-Induced Ototoxicity in Neonatal Intensive Care – JAMA Pediatrics

Editorial: Genetic Testing in Newborns Moves From Rare to Routine Application

Commentary on Twitter

The MT-RNR1 m.1555A>G variant predisposes to profound aminoglycoside-induced ototoxicity
The MT-RNR1 POCT was able to genotype the m.1555A>G variant in 26 minutes. #IDTwitter #medtwitter #TwitteRx #MedEd #PIDTwitter https://t.co/BbkpNMiNHN

— Antibiotic Steward Bassam Ghanem (@ABsteward) March 21, 2022

RCT: Nebulized Poractant Alfa in premature babies with respiratory distress syndrome.

21 Mar, 2022 | 08:25h | UTC

A Randomized, Controlled Trial to Investigate the Efficacy of Nebulized Poractant Alfa in Premature Babies with Respiratory Distress Syndrome – The Journal of Pediatrics

Commentary: Should we give up on nebulised surfactant? – Neonatal Research

Commentary on Twitter

The CURONEB RCT by Dani et al. in @JPediatr stopped early, but showed that nebulised poractant alfa is safe but does not reduce respiratory failure within 72 hours in 28-33 weekers https://t.co/gW57rPTd4f #FOAMneo #EBNEOalerts #neoEBM #neotwitter pic.twitter.com/G5Cii33fRD

— Evidence-Based Neo (@EBNEO) March 8, 2022

How to: Clostridioides difficile infection in children.

16 Mar, 2022 | 08:39h | UTC

How to: Clostridioides difficile infection in children – Clinical Microbiology and Infection

Observational Study: Comparison of intracranial pressure measurements before and after hypertonic saline or mannitol treatment in children with severe traumatic brain injury.

14 Mar, 2022 | 00:51h | UTC

Comparison of Intracranial Pressure Measurements Before and After Hypertonic Saline or Mannitol Treatment in Children With Severe Traumatic Brain Injury – JAMA Network Open

Invited Commentary: ADAPTing to a New Era of Comparative Effectiveness Research in Traumatic Brain Injury—Generating Evidence From Observational Data – JAMA Network Open

Commentary on Twitter

For children with severe TBI, hypertonic saline is recommended in published guidelines. However, mannitol is in wide-spread clinical use. In this comparative effectiveness, hypertonic saline was associated with improved ICP compared to mannitol. https://t.co/7JW224Dbio

— JAMA Network Open (@JAMANetworkOpen) March 10, 2022

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