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Pediatrics – Critical Care & Emergencies

M-A: Intelligence outcome of pediatric intensive care unit survivors.

8 Jun, 2022 | 10:36h | UTC

Intelligence outcome of pediatric intensive care unit survivors: a systematic meta-analysis and meta-regression – BMC Medicine

 


Systematic Review: Positioning for acute respiratory distress in hospitalized infants and children.

7 Jun, 2022 | 11:17h | UTC

Positioning for acute respiratory distress in hospitalised infants and children – Cochrane Library

Summary: Positioning for hospitalised infants and children with acute respiratory distress

 


State of the Art Review | Dengue: A growing problem with new interventions.

2 Jun, 2022 | 10:54h | UTC

Dengue: A Growing Problem With New Interventions – Pediatrics

 


Systematic Review: Corticosteroids for the treatment of Kawasaki disease in children.

1 Jun, 2022 | 11:05h | UTC

Corticosteroids for the treatment of Kawasaki disease in children – Cochrane Library

Summary: Using corticosteroids to treat Kawasaki disease – Cochrane Library

 


M-A: Prevalence of respiratory viruses in community-acquired pneumonia in children.

1 Jun, 2022 | 10:57h | UTC

Prevalence of respiratory viruses in community-acquired pneumonia in children: a systematic review and meta-analysis – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Recommendation document on rapid intravenous rehydration in acute gastroenteritis.

31 May, 2022 | 11:27h | UTC

Recommendation document on rapid intravenous rehydration in acute gastroenteritis – Anales de Pediatría (English Edition)

 


Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019.

27 May, 2022 | 12:15h | UTC

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis – The Lancet

Commentaries:

Need for improved global measurement of early childhood respiratory syncytial virus disease – The Lancet (free registration required)

RSV kills 100,000 kids under age 5 a year worldwide – CHEST Physician

 


Systematic Review: Airway complications resulting from pediatric esophageal button battery impaction.

27 May, 2022 | 11:49h | UTC

Airway Complications Resulting From Pediatric Esophageal Button Battery Impaction: A Systematic Review – JAMA Otolaryngology-Head & Neck Surgery (free for a limited period)

Invited Commentary: Pediatric Button Battery Injuries—Current State and What’s Next? – JAMA Otolaryngology-Head & Neck Surgery

 


Modified ABCDEF-bundles for critically ill pediatric patients – what could they look like?

24 May, 2022 | 07:43h | UTC

Modified ABCDEF-Bundles for Critically Ill Pediatric Patients – What Could They Look Like? – Frontiers in Pediatrics

Related:

ABCDEF Bundle – Society of Critical Care Medicine

The ABCDEF Bundle: Science and Philosophy of How ICU Liberation Serves Patients and Families – Critical Care Medicine

 


What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both?

23 May, 2022 | 01:48h | UTC

What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science

Related:

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 3 – UK Health Security Agency

Case numbers of acute hepatitis of unknown aetiology among children in 24 countries up to 18 April 2022 compared to the previous 5 years – Eurosurveillance

Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022 – Eurosurveillance

Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens – The Lancet Gastroenterology & Hepatology

Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT

Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC

Hepatitis outbreak in children: What do we know so far? – Imperial College London

Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases

Epidemiological update: Hepatitis of unknown aetiology in children – European Centre for Disease Prevention and Control

Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 2 – UK Health Security Agency

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids – STAT

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

 


Study Commentary | Antibiotics for pediatric pneumonia: might less be enough?

17 May, 2022 | 10:39h | UTC

Antibiotics for Pediatric Pneumonia: Might Less Be Enough? – Annals of Emergency Medicine

Original Study: Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia: The CAP-IT Randomized Clinical Trial – JAMA

Related:

Extended Versus Standard Antibiotic Course Duration in Children <5 Years of Age Hospitalized With Community-acquired Pneumonia in High-risk Settings: Four-week Outcomes of a Multicenter, Double-blind, Parallel, Superiority Randomized Controlled Trial – The Pediatric Infectious Disease Journal

Short- vs Standard-Course Outpatient Antibiotic Therapy for Community-Acquired Pneumonia in Children: The SCOUT-CAP Randomized Clinical Trial – JAMA Pediatrics

Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of Physicians – Annals of Internal Medicine

Short-Course Antimicrobial Therapy for Pediatric Community-Acquired Pneumonia: The SAFER Randomized Clinical Trial – JAMA Pediatrics

Treatment of UTIs in Infants <2 Months: A Living Systematic Review – Hospital Pediatrics

Effect of 7 vs 14 Days of Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With Urinary Tract Infection: A Randomized Clinical Trial – JAMA

Seven versus fourteen Days of Antibiotic Therapy for uncomplicated Gram-negative Bacteremia: a Non-inferiority Randomized Controlled Trial – Clinical Infectious Diseases

Efficacy of short-course antibiotic treatments for community-acquired pneumonia in adults: A systematic review and meta-analysis – Antimicrobial Agents and Chemotherapy

 


Hypotheses | Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens.

16 May, 2022 | 02:22h | UTC

Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens – The Lancet Gastroenterology & Hepatology

Related:

Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC

Hepatitis outbreak in children: What do we know so far? – Imperial College London

Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases

Epidemiological update: Hepatitis of unknown aetiology in children – European Centre for Disease Prevention and Control

Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 2 – UK Health Security Agency

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids – STAT

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

 

Commentary on Twitter

 


Systematic Review: Ultrasound for pediatric peripheral intravenous catheter insertion.

16 May, 2022 | 01:28h | UTC

Ultrasound for Pediatric Peripheral Intravenous Catheter Insertion: A Systematic Review – Pediatrics

 


Epidemiological update: Hepatitis of unknown etiology in children.

12 May, 2022 | 10:12h | UTC

Epidemiological update: Hepatitis of unknown aetiology in children – European Centre for Disease Prevention and Control

Related:

Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 2 – UK Health Security Agency

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids – STAT

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

 

Commentary on Twitter (thread – click for more)

 


Group B streptococcus infection during pregnancy and infancy: estimates of regional and global burden.

12 May, 2022 | 10:03h | UTC

Group B streptococcus infection during pregnancy and infancy: estimates of regional and global burden – The Lancet Global Health

Invited Commentary: Variation of invasive neonatal GBS disease across the regions – The Lancet Global Health

 

Commentary on Twitter

 


Diagnostic stewardship tied to fewer blood cultures, antibiotics in sick kids.

9 May, 2022 | 01:23h | UTC

Commentary: Diagnostic stewardship tied to fewer blood cultures, antibiotics in sick kids – CIDRAP

Original Study: Association of Diagnostic Stewardship for Blood Cultures in Critically Ill Children With Culture Rates, Antibiotic Use, and Patient Outcomes: Results of the Bright STAR Collaborative – JAMA Peditrics

News Release: Hospitals can reduce antibiotic overuse by avoiding unnecessary blood draws in critically ill children, study shows – Johns Hopkins University School of Medicine

 

Commentary on Twitter

 


Podcast: Appendicitis Pearls.

9 May, 2022 | 01:15h | UTC

#49: Appendicitis – Tips and Tricks For When It’s the Appendix – The Cribsiders

 


With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids.

5 May, 2022 | 10:59h | UTC

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids – STAT

Related:

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

 


Review: Mechanical ventilation in pediatric and neonatal patients.

4 May, 2022 | 10:29h | UTC

Mechanical Ventilation in Pediatric and Neonatal Patients – Frontiers in Physiology

 


AAP Guidance for structuring a pediatric intermediate care unit.

3 May, 2022 | 10:55h | UTC

Guidance for Structuring a Pediatric Intermediate Care Unit – Pediatrics

 


CDC Report: Acute hepatitis and adenovirus infection among children.

2 May, 2022 | 00:46h | UTC

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

Commentaries:

CDC releases new clinical details in cases of unusual hepatitis in children – CNN

CDC describes 4 tell-tale physical symptoms of the mysterious liver disease that’s spreading among kids in the US and Europe – Insider

CDC report finds no Covid link in children’s hepatitis cases in Alabama – NBC News

Related:

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

 

Commentaries on Twitter

 


ECDC publishes Rapid Risk Assessment – Increase in severe acute hepatitis cases of unknown etiology in children.

2 May, 2022 | 00:44h | UTC

ECDC publishes Rapid Risk Assessment – Increase in severe acute hepatitis cases of unknown aetiology in children – European Centre for Disease Prevention and Control

Related:

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

 


Hepatitis outbreak in children: explainer on adenovirus type 41, the possible culprit.

29 Apr, 2022 | 11:07h | UTC

Hepatitis outbreak in children: explainer on adenovirus type 41, the possible culprit – The Conversation

Related:

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

 


RCT: Nasal high-flow therapy during neonatal endotracheal intubation.

28 Apr, 2022 | 08:07h | UTC

Nasal High-Flow Therapy during Neonatal Endotracheal Intubation – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Successful Intubations Up With Nasal High-Flow Therapy in Neonates – HealthDay

 

Commentary on Twitter

 


RCT: Noninvasive high-frequency oscillatory ventilation vs. nasal continuous positive airway pressure vs. nasal intermittent positive pressure ventilation as postextubation support for preterm neonates.

27 Apr, 2022 | 07:59h | UTC

Noninvasive High-Frequency Oscillatory Ventilation vs Nasal Continuous Positive Airway Pressure vs Nasal Intermittent Positive Pressure Ventilation as Postextubation Support for Preterm Neonates in China: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)

 

Commentaries on Twitter

 


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