Pediatrics – Critical Care & Emergencies | Page 7 of 12 | Links Medicus Content Curation & Alerts in Medicine

Report from Alabama of acute hepatitis & adenovirus infection in young kids, Oct 21-Feb 22. 9 cases, all had adenovirus, 5/5 tested +ve for Adenovirus type 41. No epi links found. All under 6 yrs of age, immunocompetent, & no significant comorbidities. https://t.co/DcgcfN3KHo

— Andrew Lee is heading to @andrewleedr.bsky.social (@andrewleedr) April 29, 2022

New report from @CDCMMWR on the 9 episodes of severe acute hepatitis in children from Alabama

All 9 positive for Adenovirus on whole blood PCR (all 5 samples sequences were type 41)

None PCR positive for #SARSCoV2

HT @tonisoriano66 https://t.co/h9LmHeVHEf

— Alasdair Munro (@apsmunro) April 29, 2022

ECDC publishes Rapid Risk Assessment – Increase in severe acute hepatitis cases of unknown etiology in children.

2 May, 2022 | 00:44h | UTC

ECDC publishes Rapid Risk Assessment – Increase in severe acute hepatitis cases of unknown aetiology in children – European Centre for Disease Prevention and Control

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

Hepatitis outbreak in children: explainer on adenovirus type 41, the possible culprit.

29 Apr, 2022 | 11:07h | UTC

Hepatitis outbreak in children: explainer on adenovirus type 41, the possible culprit – The Conversation

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

RCT: Nasal high-flow therapy during neonatal endotracheal intubation.

28 Apr, 2022 | 08:07h | UTC

Nasal High-Flow Therapy during Neonatal Endotracheal Intubation – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Successful Intubations Up With Nasal High-Flow Therapy in Neonates – HealthDay

Commentary on Twitter

Nasal high-flow therapy during neonatal endotracheal intubation increased the likelihood of successful intubation on the first attempt without physiological instability. https://t.co/JWRgtAcoAN pic.twitter.com/EQdFW6pojF

— NEJM (@NEJM) April 27, 2022

RCT: Noninvasive high-frequency oscillatory ventilation vs. nasal continuous positive airway pressure vs. nasal intermittent positive pressure ventilation as postextubation support for preterm neonates.

27 Apr, 2022 | 07:59h | UTC

Noninvasive High-Frequency Oscillatory Ventilation vs Nasal Continuous Positive Airway Pressure vs Nasal Intermittent Positive Pressure Ventilation as Postextubation Support for Preterm Neonates in China: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)

Commentaries on Twitter

In this randomized clinical trial, NHFOV and nasal intermittent positive pressure ventilation in neonates provided a small advantage of reduced need for invasive respiratory support when used from extubation and until discharge. https://t.co/qCtNP8Gwj9

— JAMA Pediatrics (@JAMAPediatrics) April 25, 2022

A RCT in @JAMAPediatrics evaluates total duration of mechanical ventilation, need for reintubation, and ventilator-free days after extubation to either NHFOV, NCPAP or NIPPV. https://t.co/krwwMv2Hbr #EBNEOalerts #neoEBM #neotwitter pic.twitter.com/uenwdlZfO4

— Evidence-Based Neo (@EBNEO) April 27, 2022

M-A: Efficacy and safety of laparoscopy for mild and moderate pediatric abdominal trauma.

27 Apr, 2022 | 07:39h | UTC

Efficacy and Safety of Laparoscopy for Mild and Moderate Pediatric Abdominal Trauma: A Systematic Review and Meta-Analysis – Journal of Clinical Medicine

Giant tube slides and broken legs: why the latest playground craze is a serious hazard.

26 Apr, 2022 | 07:50h | UTC

Giant tube slides and broken legs: why the latest playground craze is a serious hazard – The Conversation

WHO: Multi-country – acute, severe hepatitis of unknown origin in children.

25 Apr, 2022 | 01:13h | UTC

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

Commentaries:

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

At least one child has died from mystery strain of severe hepatitis, WHO confirms – The Guardian

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention AND Guidance: Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

Review: The brain in pediatric critical care: unique aspects of assessment, monitoring, investigations, and follow-up.

25 Apr, 2022 | 00:26h | UTC

The brain in pediatric critical care: unique aspects of assessment, monitoring, investigations, and follow-up – Intensive Care Medicine

Commentary on Twitter

The brain in #PICU
🧠vulnerable brains
🧠(age-appropriate) tools to assess neuro-function
🧠latest evidence related to neurocritical care monitoring in #PedsICU
🧠post discharge: PICS‑p & approaches for neurodevelopmental follow‑up #FOAMcc #FOAMped
📎 https://t.co/F8c1L7ysPy pic.twitter.com/zsXe3Tv5ns

— Intensive Care Medicine (@yourICM) April 22, 2022

CDC alerts providers to hepatitis cases of unknown origin.

22 Apr, 2022 | 09:34h | UTC

News Release: CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

See Guidance: Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Commentaries:

CDC issues health advisory about acute hepatitis in children – CNN

CDC Issues Alert for Hepatitis in Children With Adenovirus Infection – WebMD

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

Systematic Review: Continuous positive airway pressure (CPAP) for acute bronchiolitis in children.

20 Apr, 2022 | 09:02h | UTC

Continuous positive airway pressure (CPAP) for acute bronchiolitis in children – Cochrane Library

Summary: Continuous positive airway pressure (CPAP) for acute bronchiolitis in children – Cochrane Library

Analysis of an intervention for emergency medical services personnel to reduce epinephrine dosing errors in infants.

19 Apr, 2022 | 01:52h | UTC

Analysis of an Intervention for Emergency Medical Services Personnel to Reduce Epinephrine Dosing Errors in Infants – JAMA Network Open

Commentary on Twitter

In this QI study, an infant resuscitation simulation intervention using 1mL syringes to draw up epinephrine (vs dosing from prefilled 10mL syringes) was associated with increased appropriate epinephrine use & fewer dosage errors, in less time. https://t.co/M3ztB1LMDi

— JAMA Network Open (@JAMANetworkOpen) April 15, 2022

Study showed low rates of severe COVID-19 in children hospitalized with confirmed SARS-CoV-2 infection.

14 Apr, 2022 | 08:49h | UTC

Very low rates of severe COVID-19 in children hospitalised with confirmed SARS-CoV-2 infection in London, England – Journal of Infection

Commentary: Severe COVID-19 extremely rare among children – News Medical

[Preprint] Risk of Hospitalization, severe disease, and mortality due to COVID-19 in children with SARS-CoV-2 infection in Germany – “overall hospitalization rate associated with SARS-CoV-2 infection was 35.9 per 10,000 children, ICU admission rate was 1.7 per 10,000 and case fatality was 0.09 per 10,000”.

Deaths in children and young people in England after SARS-CoV-2 infection during the first pandemic year – “In total, 99.995% of children and young people with a positive SARS-CoV-2 test survived”.

Editorial: COVID-19 vaccines for children – “Although it is true that most children experience asymptomatic or mild disease, some will get quite sick, and a small number will die. It’s why children are vaccinated against influenza, meningitis, chickenpox, and hepatitis”.

COVID-19 disease severity in children infected with the Omicron variant.

Risk factors for PICU admission and death among children and young people hospitalized with COVID-19 and PIMS-TS in England during the first pandemic year.

Study identifies risk factors for severe CoviD-19 in children.

A nationwide cohort study in Denmark showed Long Covid in children is rare and mainly of short duration.

International study identifies predictors of severe outcomes in children with COVID-19.

AHA Scientific Statement: SARS-CoV-2 infection and associated cardiovascular manifestations and complications in children and young adults.

12 Apr, 2022 | 09:59h | UTC

SARS-CoV-2 Infection and Associated Cardiovascular Manifestations and Complications in Children and Young Adults: A Scientific Statement From the American Heart Association – Circulation

News Release: Heart issues after COVID-19 uncommon in children and young adults, more research needed – American Heart Association

Commentary: COVID-19 CV Complications in Children Are Rare, Treatable: AHA Statement – TCTMD

Cohort Study: Predictors of severe illness in children with multisystem inflammatory syndrome after SARS-CoV-2 infection.

12 Apr, 2022 | 09:57h | UTC

Predictors of severe illness in children with multisystem inflammatory syndrome after SARS-CoV-2 infection: a multicentre cohort study – Canadian Medical Association Journal

News Release: Children older than 5 at higher risk of COVID-19-related multisystem inflammatory syndrome – Canadian Medical Association Journal

Commentary: Older Kids More Vulnerable to MIS-C: Study – HealthDay

RCT: In critically ill children requiring noninvasive respiratory support following extubation, high-flow nasal cannula therapy was NOT noninferior to CPAP, resulting in increased time to liberation from respiratory support.

8 Apr, 2022 | 11:07h | UTC

Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Following Extubation on Liberation From Respiratory Support in Critically Ill Children: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Selecting Intermediate Respiratory Support Following Extubation in the Pediatric Intensive Care Unit – JAMA (free for a limited period)

News Release: Trial identifies most effective breathing support for children in intensive care – Imperial College London

Commentary on Twitter

In this study, among critically ill children requiring noninvasive respiratory support following extubation, HFNC vs CPAP failed to meet the criterion for noninferiority for time to liberation from respiratory support. https://t.co/X1lNAO28le #CCR pic.twitter.com/XBnUpsqUNq

— JAMA (@JAMA_current) April 7, 2022

Review: Understanding pediatric ventilation in the operative setting.

6 Apr, 2022 | 08:42h | UTC

Part I: Physical principles of monitoring in the modern anesthesia workstation – Pediatric Anesthesia

Part II: Setting perioperative ventilation – Pediatric Anesthesia

Review: Developmental respiratory physiology.

6 Apr, 2022 | 08:41h | UTC

Developmental respiratory physiology – Pediatric Anesthesia

Update on ventilatory management of extremely preterm infants—A Neonatal Intensive Care Unit perspective.

6 Apr, 2022 | 08:40h | UTC

Update on ventilatory management of extremely preterm infants—A Neonatal Intensive Care Unit perspective – Pediatric Anesthesia

Review: Novel ventilation techniques in children.

6 Apr, 2022 | 08:38h | UTC

Novel ventilation techniques in children – Pediatric Anesthesia

Cluster RCT: Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation.

1 Apr, 2022 | 10:01h | UTC

Abstract: Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation: the SANDWICH cluster stepped-wedge RCT – Health Technology Assessment

Download: Full Report

Development of a consensus-based definition of Focused Assessment with Sonography for Trauma (FAST) in children.

1 Apr, 2022 | 08:35h | UTC

Development of a Consensus-Based Definition of Focused Assessment With Sonography for Trauma in Children – JAMA Network Open

Commentaries:

New FAST Definitions May Improve Trauma Assessment of Children – Medscape (free registration required)

Ultrasonographic views, landmarks, and patient-specific factors to consider in a consensus-based definition of the Focused Assessment With Sonography for Trauma in children with abdominal injury – Physician’s Weekly

Commentary on Twitter

Qualitative study describes the development of an expert definition for high-quality & accurate pediatric Focused Assessment with Sonography for Trauma (FAST), including recommended views, landmarks & imaging quality. @aaronkornblith @nkpluso @pocusnetwork https://t.co/4CTvGp2Rqs

— JAMA Network Open (@JAMANetworkOpen) March 18, 2022

Podcast: Deep dive into deep neck infections in children.

31 Mar, 2022 | 07:57h | UTC

#47: Deep Dive into Deep Neck Infections with Dr. Travis Crook – The Cribsiders

Podcast: Neonatal acute kidney injury pearls.

31 Mar, 2022 | 07:58h | UTC

#46: NephMadness 2022: Neonatal AKI – The Cribsiders

Cohort Study: Short-term outcomes of corticosteroid monotherapy in multisystem inflammatory syndrome in children.

30 Mar, 2022 | 10:40h | UTC

Short-term Outcomes of Corticosteroid Monotherapy in Multisystem Inflammatory Syndrome in Children – JAMA Pediatrics

Commentary on Twitter

In this study, corticosteroid monotherapy successfully treated a subset of patients with mild multisystem inflammatory syndrome in children. https://t.co/fuhHeBSaRp

— JAMA Pediatrics (@JAMAPediatrics) March 28, 2022

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