Pediatrics (all articles)
M-A: Parenting interventions to promote early child development in the first three years of life.
3 Jun, 2021 | 10:37h | UTC
Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men.
2 Jun, 2021 | 08:37h | UTCIsrael reports link between rare cases of heart inflammation and COVID-19 vaccination in young men – Science (a few articles per month are free)
Commentary on Twitter
https://twitter.com/rfsquared/status/1399803644288061442
M-A: Delivery room interventions for hypothermia in preterm neonates – “use of a plastic bag or wrap with a plastic cap or with heated humidified gas was associated with lower risk of major brain injury and mortality”.
1 Jun, 2021 | 08:10h | UTCDelivery Room Interventions for Hypothermia in Preterm Neonates: A Systematic Review and Network Meta-analysis – JAMA Pediatrics (link to abstract – $ for full-text)
RCT: Among children with protracted bacterial bronchitis, a 4-week course of amoxicillin–clavulanate is not better than a 2-week course in achieving clinical cure by 28 days.
31 May, 2021 | 08:02h | UTCCommentary: Four weeks of antibiotics for kids’ chronic cough no better than 2, study finds – CIDRAP
Commentary on Twitter
NEW Research—4 weeks of amoxicillin–clavulanate for children with chronic wet cough and suspected PBB confers little advantage vs 2 weeks in achieving clinical cure by 28 days
RCT from Tom Ruffles & colleagues https://t.co/77w08dZ20z pic.twitter.com/LYgOeJbDX8
— The Lancet Respiratory Medicine (@LancetRespirMed) May 26, 2021
RCT: Pfizer-BioNTech Covid-19 vaccine shows 100% efficacy in adolescents – mainly transient mild-to-moderate reactogenicity was frequently observed, such as injection-site pain (in 79 to 86% of participants), fatigue (in 60 to 66%), and headache (in 55 to 65%).
28 May, 2021 | 08:24h | UTC
Commentary on Twitter
The 12-15 year-olds mRNA vaccine randomized, placebo-controlled clinical trial is published @NEJM today [@BioNTech_Group/@Pfizer]https://t.co/7GlgC9xdd0
—100% efficacy (95% CI 75,100)
—1.8 X higher levels of neutralizing antibodies than 16-25 yr olds
—very good safety profile pic.twitter.com/hQzkpuA5Nu— Eric Topol (@EricTopol) May 27, 2021
Moderna says its Covid vaccine is 100% effective in teens, plans to seek FDA OK in early June.
27 May, 2021 | 08:25h | UTCModerna says its Covid vaccine is 100% effective in teens, plans to seek FDA OK in early June – CNBC
Commentary on Twitter
BREAKING: Moderna study of more than 3,700 12- to 17-year olds found 100% effficacy in those who received 2-dose #covid19 #vaccine, no significant safety problems. Will apply for FDA authorization.https://t.co/l0MHiLjCcA
— Leana Wen, M.D. (@DrLeanaWen) May 25, 2021
Study suggests it is safe to discontinue antiseizure medication for most neonates with acute symptomatic seizures prior to discharge from the hospital.
27 May, 2021 | 08:14h | UTCSafety of Early Discontinuation of Antiseizure Medication After Acute Symptomatic Neonatal Seizures – JAMA Neurology (free for a limited period)
Editorial: Discontinuing Antiseizure Medication in Neonates With Acute Symptomatic Seizures—Primum non nocere – JAMA Neurology (free for a limited period)
Commentaries: Stopping Antiseizure Medication After Acute Symptomatic Neonatal Seizures Is Found to Be Safe – Neurology Today AND Babies with Seizures May Be Overmedicated – Michigan Medicine
Commentary on Twitter
New CER study on @JAMANeuro finds no difference in functional neurodevelopment or epilepsy at 24 mnths in children whose antiseizure meds was discont'd vs maintained at discharge after resolution of acute symptomatic neonatal seizures: https://t.co/yvKbrJuCvQ #ebneoalerts #neoEBM pic.twitter.com/810weSUSgb
— Evidence-Based Neo (@EBNEO) May 26, 2021
RCT: Immediate “kangaroo mother care” improves survival in infants with low birth weight compared to conventional care with “kangaroo mother care” initiated after stabilization.
27 May, 2021 | 08:18h | UTCCommentary: Immediate skin-to-skin contact after birth improves survival of pre-term babies – Karolisnka Institutet
Related: RCT: Community-initiated kangaroo mother care reduced the risk of moderate-to-severe maternal postpartum depressive symptoms among mothers of low-birth-weight infants in low-income areas in India AND WHO: New research highlights risks of separating newborns from mothers during COVID-19 pandemic AND Randomized Trial: Kangaroo Mother Care Improves Survival of Infants with Low Birthweight
Meta-analysis: New generation antidepressants for depression in children and adolescents – “most newer antidepressants may reduce depression symptoms in a small and unimportant way compared with placebo”.
25 May, 2021 | 08:40h | UTC
AAP Clinical Report: Collaborative care in the identification and management of psychosis in adolescents and young adults.
25 May, 2021 | 08:41h | UTC
Systematic Review: Oral dextrose gel reduces the risk of neonatal hypoglycemia in at‐risk infants and probably reduces the risk of major neurological disability at two years.
25 May, 2021 | 08:38h | UTCOral dextrose gel to prevent hypoglycaemia in at‐risk neonates – Cochrane Library
Summary: Oral dextrose gel for prevention of low blood glucose levels in newborn babies – Cochrane Library
Transfusion management of severe anemia in African children: a consensus algorithm.
25 May, 2021 | 08:32h | UTC
CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.
24 May, 2021 | 08:41h | UTCCommentaries: C.D.C. Is Investigating a Heart Problem in a Few Young Vaccine Recipients – The New York Times AND U.S. CDC looking into heart inflammation in some young vaccine recipients – Reuters
Related: Israel said probing link between Pfizer shot and heart problem in men under 30 – The Times of Israel
RCT: In Africa, children hospitalized with severe pneumonia with oxygen saturations between 80 and 91% who did not receive oxygen had comparable mortality to children who received oxygen.
21 May, 2021 | 08:30h | UTC
Commentary on Twitter
COAST RCT O2 in African children >28 days w severe pneumonia, less is more!
SO2 80-91%? no O2 ➡️48h mortality comparable to low-flow O2/HFNC. O2-sparing strategies potentially offer cost-effective approaches to reduce requirements in low resource settings. https://t.co/8JHit94WQY pic.twitter.com/EEIybSOlmy— Intensive Care Medicine (@yourICM) May 6, 2021
M-A: Low prevalence of bacterial meningitis among well-appearing febrile infants aged 29-60 days with positive urinalysis results – “These results suggest that for these infants, the decision to use lumbar puncture should not be guided by urinalysis results alone”.
21 May, 2021 | 08:24h | UTC
Commentary on Twitter
This metanalysis found positive urinalysis alone is not an indication for LP in well looking febrile infants >28 days old. Prevalence among UA-positive infants: 0.4% vs UA-negative infants: 0.5%. https://t.co/dTzCiLHrSg
— JAMA Network Open (@JAMANetworkOpen) May 12, 2021
Cohort study: Babies surviving Group B strep more likely to require special educational support.
21 May, 2021 | 08:27h | UTC
Systematic review: Cognitive behavioral therapy may improve outcomes for autism spectrum disorders.
21 May, 2021 | 08:21h | UTCCognitive Behavioral Therapy for Autism Spectrum Disorders: A Systematic Review – Pediatrics (link to abstract – $ for full-text)
ERS clinical practice guidelines for the diagnosis of asthma in children aged 5–16 years.
20 May, 2021 | 08:21h | UTC
Opinion | Vaccinating children before poor morally wrong, Oxford scientist says.
19 May, 2021 | 08:44h | UTCVaccinating children before poor morally wrong, Oxford scientist says – BBC
Related: WHO: Wealthy nations urged to delay youth Covid vaccines, donate to solidarity scheme AND Editorial: Vaccinating children against SARS-CoV-2 – “Hard to justify right now for most children in most countries”. AND Opinion | American Kids Can Wait – “The U.S. should delay shots for children until global vaccine-manufacturing capacity significantly expands and the crisis in India subsides”.
Guideline: Early intervention for children aged 0 to 2 years with or at high risk of cerebral palsy.
19 May, 2021 | 08:35h | UTCEarly Intervention for Children Aged 0 to 2 Years With or at High Risk of Cerebral Palsy: International Clinical Practice Guideline Based on Systematic Reviews – JAMA Pediatrics (free for a limited period)
Editorial: Early Intervention in Cerebral Palsy and Beyond (free for a limited period)
WHO and UNICEF launch new tools for the promotion of adolescent mental health.
19 May, 2021 | 08:33h | UTCNews release: WHO and UNICEF launch new tools for the promotion of adolescent mental health – World Health Organization
WHO/UNICEF Helping Adolescents Thrive programme
Helping Adolescents Thrive Toolkit
Magnificent Mei and Friends: Comic 1
The mental and brain health of children and adolescents
Commentary on Twitter (thread – click for more)
📢 NEW RELEASE : The Helping Adolescents Thrive Toolkit, developed by WHO & @UNICEF, provides guidance for people working in the health, social services, education & justice sectors on how to promote & protect adolescent mental health.
Download 👉https://t.co/gtAK7WeQC7 pic.twitter.com/x7lq6m51Ze
— World Health Organization (WHO) (@WHO) May 18, 2021
Perspective | Facebook calls links to depression inconclusive. These researchers disagree.
19 May, 2021 | 08:30h | UTCFacebook Calls Links To Depression Inconclusive. These Researchers Disagree – NPR
Related: Cohort study: Preschoolers’ extensive electronic media use linked to emotional/behavioral issues AND Analysis: Smartphones, Social Media Use and Youth Mental Health AND [Abstract Only] Study: Associations Between Time Spent Using Social Media and Mental Health Problems Among Youth AND Association of Screen Time and Depression in Adolescence AND The Adverse Effects of Social Media use on Young People’s Mental Health May be Caused by Exposure to Cyberbullying, Loss of Sleep, and Reduced Physical Activity AND Research: This Is Your Brain Off Facebook AND Cohort Study: Social Media Use and Adolescent Mental Health AND Supplement: Children, Adolescents and Screens: What We Know and What We Need To Learn
Systematic Review: Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome is associated with reduced risk of death or bronchopulmonary dysplasia, less intubation in the first 72 hours, and reduced incidence of major complications and in‐hospital mortality.
19 May, 2021 | 08:20h | UTC
Commentary on Twitter
https://twitter.com/CochraneUK/status/1393463418913443843
Opinion | E-Cigarettes and the U.S. Menthol Ban: A Missed Opportunity to Protect Youth.
18 May, 2021 | 07:28h | UTCE-Cigarettes and the U.S. Menthol Ban: A Missed Opportunity to Protect Youth – Think Global Health
Commentary on Twitter (thread – click for more)
📢📢📢 @US_FDA should ban flavors in all nicotine-containing products, not just menthol cigarettes. More than 8 out of 10 current youth e-cigarette users in the U.S. vape non-tobacco flavors.
IHME researchers for @ThinkGlobalHlth 🧵⤵️ https://t.co/d56mDCvTY3
— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) May 17, 2021
NICE Guideline Update | Headaches in over 12s: diagnosis and management.
18 May, 2021 | 07:14h | UTCHeadaches in over 12s: diagnosis and management – National Institute for Health and Care Excellence