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Pediatrics (all articles)

A nationwide cohort study in Denmark showed Long Covid in children is rare and mainly of short duration.

30 Jan, 2022 | 14:40h | UTC

Long COVID symptoms and duration in SARS-CoV-2 positive children — a nationwide cohort study – European Journal of Pediatrics

Related:

Editorial | Long covid in children and adolescents – “Risk appears low, but many questions remain”.

M-A: Persistent symptoms following SARS-CoV-2 infection among children and young people – “Higher study quality was associated with lower prevalence of all symptoms, except loss of smell and cognitive symptoms”.

Review: Long COVID symptoms in children rarely persist beyond three months.

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Do kids get long COVID? And how often? A pediatrician looks at the data – Children also get Long Covid, but much less often than adults.

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

 

Commentary on Twitter

 

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

30 Jan, 2022 | 14:34h | UTC

Myocarditis after BNT162b2 Vaccination in Israeli Adolescents – New England Journal of Medicine

Related:

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

 

Commentary on Twitter

 

RCT: Olanzapine may improve the control of vomiting in the delayed phase in children receiving highly emetogenic chemotherapy.

30 Jan, 2022 | 14:13h | UTC

Efficacy and Safety of Olanzapine in Children Receiving Highly Emetogenic Chemotherapy: A Randomized, Double-blind Placebo-controlled Phase 3 Trial – Journal of Pediatric Hematology/Oncology (link to abstract – $ for full-text)

 

Cohort study: Functional ophthalmic factors associated with extreme prematurity in young adults.

30 Jan, 2022 | 14:03h | UTC

Functional Ophthalmic Factors Associated With Extreme Prematurity in Young Adults – JAMA Network Open

Commentary: Extremely Preterm Babies Have Higher Risk of Eye Problems as Adults – MedPage Today (free registration required)

 

Commentary on Twitter

 

Cohort Study: Association of preeclampsia and perinatal complications with offspring neurodevelopmental and psychiatric disorders.

30 Jan, 2022 | 13:51h | UTC

Association of Preeclampsia and Perinatal Complications With Offspring Neurodevelopmental and Psychiatric Disorders – JAMA Network Open

 

WHO systematic review and meta-analysis: efficacy and safety of pharmacological, physical, and psychological interventions for the management of chronic pain in children.

28 Jan, 2022 | 08:27h | UTC

Efficacy and safety of pharmacological, physical, and psychological interventions for the management of chronic pain in children: a WHO systematic review and meta-analysis – Pain

 

Development and use of a calculator to measure pediatric low-value care delivered in US children’s hospitals.

28 Jan, 2022 | 08:19h | UTC

Development and Use of a Calculator to Measure Pediatric Low-Value Care Delivered in US Children’s Hospitals – JAMA Network Open

Commentary: Pediatric Services With Limited Benefits Cost Millions – MedPage Today (free registration required)

 

Review: Juvenile idiopathic arthritis.

28 Jan, 2022 | 08:13h | UTC

Juvenile idiopathic arthritis – Nature Reviews Disease Primers (if the link is paywalled, try this one)

Infographic: Juvenile idiopathic arthritis (if the link is paywalled, try this one)

 

Commentary on Twitter

 

Opinion: Despite Omicron arriving, keeping schools open as safely as possible should be the goal.

27 Jan, 2022 | 09:58h | UTC

Despite Omicron arriving, keeping schools open as safely as possible should be the goal – The Conversation

 

AAP Report: Some alternative peripartum, neonatal practices carry disease risks.

27 Jan, 2022 | 09:41h | UTC

News Release: Some alternative peripartum, neonatal practices carry disease risks: AAP report – American Academy of Pediatrics

Report: Risks of Infectious Diseases in Newborns Exposed to Alternative Perinatal Practices – Pediatrics

Commentary: Risks Discussed for Alternative Peripartum, Neonatal Practices – HealthDay

 

Impact of the COVID‐19 pandemic on pediatric oncology providers globally: A mixed‐methods study.

27 Jan, 2022 | 09:46h | UTC

Impact of the COVID‐19 pandemic on pediatric oncology providers globally: A mixed‐methods study – Cancer

Editorial: The impact of the COVID‐19 pandemic in pediatric oncology units: A lesson of resilience and hope – Cancer

News Release: How has the COVID-19 pandemic impacted clinicians who care for children with cancer? – Wiley

 

Systematic Review: Mediators between physical activity and academic achievement.

27 Jan, 2022 | 09:28h | UTC

Mediators between physical activity and academic achievement: A systematic review – Scandinavian Journal of Medicine & Science in Sports

 

RCT: In children with relapsing steroid-sensitive nephrotic syndrome with acute respiratory tract infection, a daily low dose of prednisolone did not reduce the risk of relapse.

27 Jan, 2022 | 09:32h | UTC

Evaluation of Daily Low-Dose Prednisolone During Upper Respiratory Tract Infection to Prevent Relapse in Children With Relapsing Steroid-Sensitive Nephrotic Syndrome: The PREDNOS 2 Randomized Clinical Trial – JAMA Pediatrics

Commentary: PREDNOS 2: Prednisolone Doesn’t Lower Relapse Risks in Kids with Nephrotic Syndrome – Physician’s Weekly

 

Commentary on Twitter

 

M-A: Late kidney effects of nephron-sparing vs. radical nephrectomy for Wilms Tumor.

27 Jan, 2022 | 09:22h | UTC

Late Kidney Effects of Nephron-Sparing vs Radical Nephrectomy for Wilms Tumor: A Systematic Review and Meta-Analysis – The Journal of Urology (link to abstract – $ for full-text)

 

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

26 Jan, 2022 | 02:23h | UTC

Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021 – JAMA

Commentary: COVID 19: Risk of Myocarditis Highest Following Second Vaccine Dose Among Adolescent and Young Adult Males – MedicalResearch.com

Related:

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

 

Systematic Review: Delayed introduction of progressive enteral feeds to prevent necrotizing enterocolitis in very low birth weight infants.

26 Jan, 2022 | 01:27h | UTC

Delayed introduction of progressive enteral feeds to prevent necrotising enterocolitis in very low birth weight infants – Cochrane Library

Summary: Delayed introduction of progressive enteral feeds to prevent necrotising enterocolitis in very low birth weight infants – Cochrane Library

 

Systematic Review: Short intravenous antibiotic courses for urinary infections in young infants.

26 Jan, 2022 | 01:24h | UTC

Short Intravenous Antibiotic Courses for Urinary Infections in Young Infants: A Systematic Review – Pediatrics (link to abstract – $ for full-text)

 

WHO drops opposition to boosters – recommends third Pfizer jab for adults & two vaccines for children ages 5 & up.

25 Jan, 2022 | 09:45h | UTC

WHO Drops Opposition to Boosters – Recommends Third Pfizer Jab for Adults & Two Vaccines for Children Ages 5 & Up – Health Policy Watch

Related:

WHO updated roadmap for prioritizing uses of COVID-19 vaccines.

WHO advisers weigh in on COVID-19 boosters, Pfizer vaccine in younger kids.

 

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

25 Jan, 2022 | 09:43h | UTC

Carditis After COVID-19 Vaccination With a Messenger RNA Vaccine and an Inactivated Virus Vaccine: A Case–Control Study – Annals of Internal Medicine

News release: BNT162b2 COVID-19 vaccine associated with increased risk of carditis – American College of Physicians

Related:

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

 

ASH-ASPHO Choosing Wisely Campaign: 5 hematologic tests and treatments to question in children.

25 Jan, 2022 | 09:33h | UTC

The ASH-ASPHO Choosing Wisely Campaign: 5 hematologic tests and treatments to question – Blood Advances

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 

Guidelines on Screen Time and Digital Wellness in Infants, Children and Adolescents – “children below 2 years age should not be exposed to any type of screen, whereas exposure should be limited to a maximum of one hour of supervised screen time per day for children 24-59 months age, and less than two hours per day for children 5-10 years age”.

25 Jan, 2022 | 09:30h | UTC

Indian Academy of Pediatrics Guidelines on Screen Time and Digital Wellness in Infants, Children and Adolescents

Related Guideline: Media and Young Minds – American Academy of Pediatrics

 

Podcast: Inflammatory bowel disease in children.

25 Jan, 2022 | 09:18h | UTC

#42: Inflammatory Bowel Disease – Go With Your Gut – The Cribsiders

 

Global, regional, and national time trends in mortality for congenital heart disease, 1990–2019: An age-period-cohort analysis for the Global Burden of Disease 2019 study.

25 Jan, 2022 | 09:13h | UTC

Global, regional, and national time trends in mortality for congenital heart disease, 1990–2019: An age-period-cohort analysis for the Global Burden of Disease 2019 study – EClinicalMedicine

 

Commentary on Twitter

 

WHO advisers weigh in on COVID-19 boosters, Pfizer vaccine in younger kids.

24 Jan, 2022 | 08:35h | UTC

WHO advisers weigh in on COVID-19 boosters, Pfizer vaccine in younger kids – CIDRAP

See also: Interim recommendations for use of the Pfizer–BioNTech COVID-19 vaccine, BNT162b2, under Emergency Use Listing – World Health Organization

 

RCT: In children with peanut allergy, initiation of peanut oral immunotherapy before age 4 years induced desensitization in 71% of patients and remission in 21%.

24 Jan, 2022 | 08:18h | UTC

Efficacy and safety of oral immunotherapy in children aged 1–3 years with peanut allergy (the Immune Tolerance Network IMPACT trial): a randomised placebo-controlled study – The Lancet (link to abstract – $ for full-text)

News Release: Oral immunotherapy induces remission of peanut allergy in some young children – NIH News Releases

Commentary: Peanut Oral Immunotherapy at Younger Age Ups Desensitization in Children – HealthDay

 

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