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Pediatrics (all articles)

Extending the reach of antimicrobial stewardship to pediatric patients.

10 Mar, 2022 | 10:12h | UTC

Extending the Reach of Antimicrobial Stewardship to Pediatric Patients – Infectious Diseases and Therapy

 


ACR/Vasculitis Foundation Guideline for the management of Kawasaki Disease.

9 Mar, 2022 | 10:01h | UTC

2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Kawasaki Disease

 


Association of acute respiratory failure in early childhood with long-term neurocognitive outcomes.

9 Mar, 2022 | 08:41h | UTC

Association of Acute Respiratory Failure in Early Childhood With Long-term Neurocognitive Outcomes – JAMA (link to abstract – $ for full-text)

Commentaries:

IQ Lower for Survivors of PICU Respiratory Failure Hospitalization – HealthDay

Investigating The Effects of Critical Illness in Early Childhood On Neurocognitive Outcomes – University of Pennsylvania School of Nursing

 


RCT: Azithromycin is not effective for the prevention of recurrent wheeze following severe respiratory syncytial virus bronchiolitis.

8 Mar, 2022 | 08:49h | UTC

Azithromycin to Prevent Recurrent Wheeze Following Severe Respiratory Syncytial Virus Bronchiolitis – NEJM Evidence

Commentaries:

Study finds azithromycin use during RSV not useful in preventing recurrent wheezing, may cause harm – Vanderbilt University Medical Center

Antibiotic doesn’t prevent future wheezing in babies hospitalized with RSV – Washington University in St. Louis

 

Commentary on Twitter

 


CDC, AAP update developmental milestones for surveillance program.

8 Mar, 2022 | 08:47h | UTC

News Release: CDC, AAP update developmental milestones for surveillance program – AAP News

See Guidance: Evidence-Informed Milestones for Developmental Surveillance Tools – Pediatrics

Commentaries:

Revised Developmental Milestone Guidelines For Infants And Toddlers: Explained Here – Forbes

Much Awaited – Development Milestone Checklists Updated by CDC & AAP – Pediatric OnCall

 


FDA issues warning after 2 children strangled by enteral feeding set tubing.

8 Mar, 2022 | 08:33h | UTC

FDA issues warning after 2 children strangled by enteral feeding set tubing – AAP News

Original Report: Potential Risk of Strangulation in Children who Use Enteral Feeding Delivery Sets – U.S. Food & Drug Administration

 


Podcast: Pediatric cancer survivorship.

8 Mar, 2022 | 08:26h | UTC

#44: Pediatric Cancer Survivorship – Focusing on Thriving, Not Just Surviving – The Cribsiders

 


Podcast: Neonatal Hyperbilirubinemia.

8 Mar, 2022 | 08:27h | UTC

#45: Neonatal Hyperbilirubinemia – Their Future’s So Bright, They Gotta Wear Shades! – The Cribsiders

 


RCT: Supplementing milk with enteral recombinant human insulin in preterm infants is safe and results in earlier achievement of full enteral feeding.

6 Mar, 2022 | 23:58h | UTC

Efficacy and Safety of Enteral Recombinant Human Insulin in Preterm Infants: A Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)

Commentary: Enteral insulin reduces the duration of feeding intolerance in preterm infants – MedPage Today (free registration required)

 

Commentary on Twitter

 


Cohort Study: Association between screen time exposure in children at 1 year of age and autism spectrum disorder at 3 years of age.

4 Mar, 2022 | 09:54h | UTC

Association Between Screen Time Exposure in Children at 1 Year of Age and Autism Spectrum Disorder at 3 Years of Age: The Japan Environment and Children’s Study – JAMA Pediatrics

Commentary: Screen Time Linked to Autism Spectrum Disorder in Boys – HealthDay

Related:

M-A: Global prevalence of meeting screen time guidelines among children 5 years and younger.

Media and Young Minds – American Academy of Pediatrics

Guidelines on Screen Time and Digital Wellness in Infants, Children and Adolescents – “children below 2 years age should not be exposed to any type of screen, whereas exposure should be limited to a maximum of one hour of supervised screen time per day for children 24-59 months age, and less than two hours per day for children 5-10 years age”.

 


ACR Guidelines for the Treatment of Juvenile Idiopathic Arthritis.

4 Mar, 2022 | 08:58h | UTC

News Release: The American College of Rheumatology releases two updated guidelines for treatment of juvenile idiopathic arthritis – American College of Rheumatology

 

2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Recommendations for Nonpharmacologic Therapies, Medication Monitoring, Immunizations, and Imaging – Arthritis & Rheumatology

 

2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Oligoarthritis, Temporomandibular Joint Arthritis, and Systemic Juvenile Idiopathic Arthritis

 


AAP Clinical Report: Recognition and management of cardiovascular insufficiency in the very low birth weight newborn.

4 Mar, 2022 | 08:54h | UTC

Recognition and Management of Cardiovascular Insufficiency in the Very Low Birth Weight Newborn – Pediatrics

 


RCT: Nirsevimab for prevention of RSV in healthy late-preterm and term infants.

3 Mar, 2022 | 09:42h | UTC

Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants – New England Journal of Medicine

Commentaries:

Nirsevimab Protects Late-Preterm, Term Infants from RSV-Related Lower RTI, Study Finds – AJMC

Nirsevimab Prophylaxis Wards Off RSV Infections in Healthy Infants— Monoclonal antibody showed 74.5% efficacy against RSV infections requiring medical care – MedPage Today (free registration required)

Related: Randomized trial: Single-dose nirsevimab for prevention of RSV in preterm infants

 


National, regional, and global causes of mortality in 5–19-year-olds from 2000 to 2019: a systematic analysis.

3 Mar, 2022 | 08:51h | UTC

National, regional, and global causes of mortality in 5–19-year-olds from 2000 to 2019: a systematic analysis – The Lancet Global Health

Invited commentary: Child and adolescent deaths: a call for strengthening mortality surveillance systems – The Lancet Global Health

 


Myocarditis following COVID-19 BNT162b2 vaccination among adolescents in Hong Kong.

3 Mar, 2022 | 08:43h | UTC

Myocarditis Following COVID-19 BNT162b2 Vaccination Among Adolescents in Hong Kong – JAMA Pediatrics

Commentary: Study: Dosing change could reduce COVID-19 vaccine heart side effect in teens – UPI

Related:

[Preprint] Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy.

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

 


Guideline: Management of Clostridioides difficile infection in hematopoietic cell transplant recipients.

3 Mar, 2022 | 08:17h | UTC

American Society for Transplantation and Cellular Therapy Series: #5 – Management of Clostridioides difficile infection in hematopoietic cell transplant recipients – Transplantation and Cellular Therapy

See other articles in the series:

American Society of Transplantation and Cellular Therapy Series, 1: Enterobacterales Infection Prevention and Management after Hematopoietic Cell Transplantation

 

American Society of Transplantation and Cellular Therapy Series, 2: Management and Prevention of Aspergillosis in Hematopoietic Cell Transplantation Recipients

 

American Society for Transplantation and Cellular Therapy Series: #3—Prevention of Cytomegalovirus Infection and Disease After Hematopoietic Cell Transplantation

 

American Society for Transplantation and Cellular Therapy Series: #4 – Cytomegalovirus treatment and management of resistant or refractory infections after hematopoietic cell transplantation

 


(Epi)genetic predisposing factors found in one-third of children diagnosed with Wilms tumor.

3 Mar, 2022 | 08:10h | UTC

Prevalence of (Epi)genetic Predisposing Factors in a 5-Year Unselected National Wilms Tumor Cohort: A Comprehensive Clinical and Genomic Characterization – Journal of Clinical Oncology

Commentary: One third of children with a kidney tumor has hereditary predisposition – Princess Máxima Center for pediatric oncology in Utrecht

 


Meta-analysis showed a 2.4-fold increased risk of cancer in patients with pediatric-onset inflammatory bowel disease.

3 Mar, 2022 | 08:06h | UTC

Development of Cancer Among Patients With Pediatric-Onset Inflammatory Bowel Disease: A Meta-analysis of Population-Based Studies – JAMA Network Open

Commentary: Kids With IBD Need Close Monitoring as They Grow Up — Meta-analysis confirms: substantially increased cancer risk in adulthood – MedPage Today (free registration required)

 


Educational Review: Multiparametric MRI evaluation of bone sarcomas in children.

3 Mar, 2022 | 07:54h | UTC

Multiparametric MRI evaluation of bone sarcomas in children – Insights into Imaging

 


[Preprint] Study shows significantly reduced effectiveness of the Pfizer vaccine in children 5 to 11 after the emergency of the Omicron variant.

1 Mar, 2022 | 08:54h | UTC

Effectiveness of the BNT162b2 vaccine among children 5-11 and 12-17 years in New York after the Emergence of the Omicron Variant – medRxiv

Commentaries:

Pfizer Covid vaccine is less effective in kids 5 to 11, study finds – STAT

Pfizer Covid-19 vaccine effectiveness fell quickly for kids during Omicron surge but still offered some protection against severe disease – CNN

More mask mandates fall as poor COVID vaccine protection noted in young kids – CIDRAP

 


At least 5 million children have lost a parent or caregiver due to COVID-19 since March 2020, updated figures suggest.

25 Feb, 2022 | 11:32h | UTC

News Release:  At least 5 million children have lost a parent or caregiver due to COVID-19 since March 2020, updated figures suggest – The Lancet

Original Study: Global, regional, and national minimum estimates of children affected by COVID-19-associated orphanhood and caregiver death, by age and family circumstance up to Oct 31, 2021: an updated modelling study – The Lancet Child & Adolescent Health

Commentaries:

Integrative approaches required to support children affected by COVID-19 – The Lancet Child & Adolescent Health

Millions of children worldwide have lost a parent or caregiver to COVID-19: “The hidden pandemic” – CBS News

Related:

More than 1.5 million children lost a primary or secondary caregiver due to the COVID-19 pandemic.

Covid-19 Has Created Thousands Of Newly Single Parents And Orphans

 

Commentary on Twitter (thread – click for more)

 


Study suggests multisystem inflammatory syndrome in children (MIS-C) is rare among vaccinated teens.

25 Feb, 2022 | 11:29h | UTC

Reported cases of multisystem inflammatory syndrome in children aged 12–20 years in the USA who received a COVID-19 vaccine, December, 2020, through August, 2021: a surveillance investigation – The Lancet Child & Adolescent Health

Commentaries:

When vaccine adverse event reporting generates hope, not fear – The Lancet Child & Adolescent Health

MIS-C rare in COVID-vaccinated teens, study finds – CIDRAP

Vaccination Greatly Reduces Odds of MIS-C in Teens Who Get COVID – HealthDay

 

Commentary on Twitter

 


Interventions for the management of transient tachypnea of the newborn ‐ an overview of systematic reviews.

25 Feb, 2022 | 11:12h | UTC

Interventions for the management of transient tachypnoea of the newborn ‐ an overview of systematic reviews – Cochrane Library

 


Systematic Review: Effect of asthma education on health outcomes in children.

25 Feb, 2022 | 11:09h | UTC

Effect of asthma education on health outcomes in children: a systematic review – Archives of Disease in Childhood

 


What’s New in Pediatric Orthopedics.

25 Feb, 2022 | 10:48h | UTC

What’s New in Pediatric Orthopaedics – The Journal of Bone & Joint Surgery

 


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