Oncology (all articles)
Position paper: Chest CT diagnosis and clinical management of drug-related pneumonitis in patients receiving molecular targeting agents and immune checkpoint inhibitors
17 Jan, 2021 | 22:07h | UTC
Study shows sharp decline in cancer screenings and diagnoses during the first COVID-19 surge
17 Jan, 2021 | 21:57h | UTCOriginal study: Cancer Screening Tests and Cancer Diagnoses During the COVID-19 Pandemic – JAMA Oncology
Nutrition in cancer care: A brief, practical guide with a focus on clinical practice
17 Jan, 2021 | 21:37h | UTC
CSCO and ASCO Guideline: Chemotherapy in combination with radiotherapy for definitive-intent treatment of stage II-IVA nasopharyngeal carcinoma
15 Jan, 2021 | 08:14h | UTC
Randomized trial: Once-per-week selinexor, bortezomib, and dexamethasone versus twice-per-week bortezomib and dexamethasone in patients with multiple myeloma
15 Jan, 2021 | 08:12h | UTCOnce-per-week selinexor, bortezomib, and dexamethasone versus twice-per-week bortezomib and dexamethasone in patients with multiple myeloma (BOSTON): a randomised, open-label, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Commentary: Triplet therapy slows refractory multiple myeloma – MedicalXpress
Systematic review: Adding abiraterone acetate to androgen deprivation therapy for the treatment of metastatic hormone-sensitive prostate cancer
15 Jan, 2021 | 08:10h | UTC
Systematic review: Immunotherapy vs. chemotherapy for people with advanced non-small cell lung cancer who have not been previously treated
14 Jan, 2021 | 01:30h | UTC
#Immunotherapy vs #chemotherapy for people with advanced non‐small cell #lungcancer who have not been not previously been treated https://t.co/RJlDp1SHTc New @CochraneLibrary systematic review includes 7 studies with 5893 participants.
— The Cochrane Library (@CochraneLibrary) December 21, 2020
Cancer Statistics, 2021. Cancer mortality dropping due to improved lung cancer treatment
14 Jan, 2021 | 01:33h | UTCCancer Statistics, 2021 – CA: A Cancer Journal for Clinicians
Commentary on Twitter
Now available! The 2021 Annual Cancer Statistics Report from @AmericanCancer shows a record drop in cancer mortality for the 2nd year in a row. Learn why: https://t.co/jltAFlNTFb pic.twitter.com/AAiEPBAb58
— CA: A Cancer Journal for Clinicians (@CAonline) January 12, 2021
NCCN Guideline: Genetic/familial high-risk assessment: breast, ovarian, and pancreatic
14 Jan, 2021 | 01:28h | UTC
Randomized trial: Adjuvant capecitabine in triple-negative breast cancer
13 Jan, 2021 | 01:40h | UTCCommentaries: Capecitabine maintenance may improve TNBC outcomes – medwire News
Commentary on Twitter
In this RCT, low-dose #capecitabine maintenance therapy for 1y resulted in improved 5-y disease-free survival vs observation among women with early-stage triple-negative breast cancer who received standard adjuvant treatment https://t.co/sIgxUSjaYe #BCSM #SABCS20 #VisualAbstract
— JAMA (@JAMA_current) January 6, 2021
Systematic review: Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy
13 Jan, 2021 | 01:37h | UTC
Blueprint for cancer research: Critical gaps and opportunities
13 Jan, 2021 | 01:36h | UTCBlueprint for cancer research: Critical gaps and opportunities – CA: A Cancer Journal for Clinicians
Randomized trial: Early interdisciplinary supportive care in patients with previously untreated metastatic esophagogastric cancer
12 Jan, 2021 | 01:36h | UTC
Commentaries on Twitter
RCT of early interdisciplinary supportive care (ESC) in metastatic esophagogastric cancer
ESC by oncologists, dietitians & psychologists
⬆️ chemo cycles from 4 to 5
⬆️ OS HR=0.68
➡️ PFS
↗️ QoL
To be considered in radiochemotherapy #radonchttps://t.co/G6WQS8ULCb— Matthias Guckenberger (@Mat_Guc) January 10, 2021
Impressive survival benefit for early integrated multidisciplinary nutritional and psychological support vs. standard of care in Phase III trial for metastatic esophagogastric cancers in @ASCO_pubs. Intervention 14.8 mo vs. SOC 11.9 mo. https://t.co/FWE6xlPH8v
— Michael Shusterman, MD (@guildsman) January 9, 2021
Randomized trial: Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) improve outcomes vs. traditional approach in locally advanced rectal cancer
12 Jan, 2021 | 01:12h | UTCShort-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)
Commentary on Twitter
New online: phase 3 RAPIDO trial: Short-course #radiotherapy followed by #chemotherapy before total mesorectal excision (TME) vs standard of care in locally advanced #rectalcancer https://t.co/bTgUC6Lo39 #crcsm pic.twitter.com/Iu3HbQ1xjG
— The Lancet Oncology (@TheLancetOncol) December 8, 2020
Meta-analysis: Total neoadjuvant therapy vs. standard therapy in locally advanced rectal cancer
12 Jan, 2021 | 01:10h | UTCCommentaries: Personalizing Treatment for Rectal Cancer: Total Neoadjuvant Therapy Is Leading the Way AND Total Neoadjuvant Therapy Improves Rectal Cancer Pathologic Response – Physician’s Weekly
Related meta-analysis (just published): Impact of Total Neoadjuvant Therapy vs. Standard Chemoradiotherapy in Locally Advanced Rectal Cancer: A Systematic Review and Meta-Analysis of Randomized Trials – Cancers
Commentary on Twitter
Systematic review & meta-analysis finds total neoadjuvant therapy for locally adv. rectal cancer is associated with a doubling of pathologic complete response vs standard chemoradiation plus by adjuvant chemo. @anup_kasi @KUMedCenter @geriradonc @agrothey https://t.co/oRccCh5bEb
— JAMA Network Open (@JAMANetworkOpen) December 16, 2020
Study suggests the intensity of active surveillance in patients with rectal cancer managed by a watch-and-wait approach could be reduced if they maintain a complete clinical response within the first 3 years
12 Jan, 2021 | 01:11h | UTCCommentaries: Rectal cancer patients who “watch and wait” may only need few years of stringent follow-up – eCancer AND Intense rectal cancer surveillance may be reduced – MDedge
Meta-analysis: Lung cancer screening using low-dose computed tomography reduces lung cancer–specific mortality, albeit with a tradeoff of likely overdiagnosis
16 Dec, 2020 | 10:08h | UTC
Randomized trial: Extensive peritoneal lavage with saline after curative gastrectomy for gastric cancer does not benefit patients vs. surgery alone
16 Dec, 2020 | 09:55h | UTCExtensive peritoneal lavage with saline after curative gastrectomy for gastric cancer (EXPEL): a multicentre randomised controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Commentary on Twitter
ICYMI – Results of the EXPEL trial show no survival benefit with extensive peritoneal #lavage after surgery vs surgery alone; not recommended for patients undergoing curative #gastrectomy for #gastriccancer.https://t.co/rCgHNt7VZ1#gitwitter #some4surgery pic.twitter.com/BC1BJgElYm
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) December 9, 2020
Brazilian Cardio-oncology Guideline – 2020
15 Dec, 2020 | 01:31h | UTCBrazilian Cardio-oncology Guideline – 2020 – Arquivos Brasileiros de Cardiologia
Randomized trial: Among patients with advanced rectal cancer, short-course radiotherapy followed by chemotherapy before total mesorectal excision reduces disease-related treatment failure compared to standard treatment
15 Dec, 2020 | 01:29h | UTC
Commentary on Twitter
New online: phase 3 RAPIDO trial: Short-course #radiotherapy followed by #chemotherapy before total mesorectal excision (TME) vs standard of care in locally advanced #rectalcancer https://t.co/bTgUC6Lo39 #crcsm pic.twitter.com/Iu3HbQ1xjG
— The Lancet Oncology (@TheLancetOncol) December 8, 2020
A nationwide study in Denmark showed a higher than expected risk of cardiac events in patients with cancer receiving immune checkpoint inhibitors
10 Dec, 2020 | 08:49h | UTC
Short review: How to diagnose and manage radiation therapy cardiotoxicity
6 Dec, 2020 | 23:27h | UTCHow to Diagnose and Manage Radiation Cardiotoxicity – JACC: CardioOncology
Case series: Shedding of viable SARS-CoV-2 after immunosuppressive therapy for cancer
2 Dec, 2020 | 07:31h | UTC
Randomized trial: Colorectal cancer screening with repeated fecal immunochemical tests detects more colorectal cancer and advanced adenomas compared to screening sigmoidoscopy
25 Nov, 2020 | 09:05h | UTCColorectal cancer screening with repeated fecal immunochemical test versus sigmoidoscopy: baseline results from a randomized trial – Gastroenterology (link to abstract – $ for full-text)
Systematic review: Interventions for breathlessness in patients with advanced cancer
23 Nov, 2020 | 09:43h | UTCFull report: Interventions for breathlessness in patients with advanced cancer
Evidence Summary: Interventions for breathlessness in patients with advanced cancer