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Oncology (all articles)

Position paper: Chest CT diagnosis and clinical management of drug-related pneumonitis in patients receiving molecular targeting agents and immune checkpoint inhibitors

17 Jan, 2021 | 22:07h | UTC

Chest CT Diagnosis and Clinical Management of Drug-related Pneumonitis in Patients Receiving Molecular Targeting Agents and Immune Checkpoint Inhibitors: A Position Paper from the Fleischner Society – Radiology

 


Study shows sharp decline in cancer screenings and diagnoses during the first COVID-19 surge

17 Jan, 2021 | 21:57h | UTC

Study shows sharp decline in cancer screenings and diagnoses during the first COVID-19 surge – Dana-Farber Cancer Institute

Original study: Cancer Screening Tests and Cancer Diagnoses During the COVID-19 Pandemic – JAMA Oncology

 


Nutrition in cancer care: A brief, practical guide with a focus on clinical practice

17 Jan, 2021 | 21:37h | UTC

Nutrition in Cancer Care: A Brief, Practical Guide With a Focus on Clinical Practice – JCO Oncology Practice

 


CSCO and ASCO Guideline: Chemotherapy in combination with radiotherapy for definitive-intent treatment of stage II-IVA nasopharyngeal carcinoma

15 Jan, 2021 | 08:14h | UTC

Chemotherapy in Combination With Radiotherapy for Definitive-Intent Treatment of Stage II-IVA Nasopharyngeal Carcinoma: CSCO and ASCO Guideline – Journal of Clinical Oncology

 


Randomized trial: Once-per-week selinexor, bortezomib, and dexamethasone versus twice-per-week bortezomib and dexamethasone in patients with multiple myeloma

15 Jan, 2021 | 08:12h | UTC

Once-per-week selinexor, bortezomib, and dexamethasone versus twice-per-week bortezomib and dexamethasone in patients with multiple myeloma (BOSTON): a randomised, open-label, phase 3 trial – The Lancet (link to abstract – $ for full-text)

Commentary: Triplet therapy slows refractory multiple myeloma – MedicalXpress

 


Systematic review: Adding abiraterone acetate to androgen deprivation therapy for the treatment of metastatic hormone-sensitive prostate cancer

15 Jan, 2021 | 08:10h | UTC

Abiraterone acetate in combination with androgen deprivation therapy compared to androgen deprivation therapy only for metastatic hormone‐sensitive prostate cancer – Cochrane Library

Summary: Adding abiraterone acetate to androgen deprivation therapy for the treatment of metastatic hormone-sensitive prostate cancer – Cochrane Library

 


Systematic review: Immunotherapy vs. chemotherapy for people with advanced non-small cell lung cancer who have not been previously treated

14 Jan, 2021 | 01:30h | UTC

Single or combined immune checkpoint inhibitors compared to first-line platinum-based chemotherapy with or without bevacizumab for people with advanced non-small cell lung cancer – Cochrane Library

Summary: Immunotherapy versus chemotherapy for people with advanced non-small cell lung cancer who have not been not previously been treated – Cochrane Library

 

 


Cancer Statistics, 2021. Cancer mortality dropping due to improved lung cancer treatment

14 Jan, 2021 | 01:33h | UTC

Cancer Statistics, 2021 – CA: A Cancer Journal for Clinicians

Commentary: Record drop in cancer mortality for second straight year due to improved lung cancer treatment – American Cancer Society

 

Commentary on Twitter

 


NCCN Guideline: Genetic/familial high-risk assessment: breast, ovarian, and pancreatic

14 Jan, 2021 | 01:28h | UTC

Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network

 


Randomized trial: Adjuvant capecitabine in triple-negative breast cancer

13 Jan, 2021 | 01:40h | UTC

Effect of Capecitabine Maintenance Therapy Using Lower Dosage and Higher Frequency vs Observation on Disease-Free Survival Among Patients With Early-Stage Triple-Negative Breast Cancer Who Had Received Standard Treatment: The SYSUCC-001 Randomized Clinical Trial – JAMA

Commentaries: Capecitabine maintenance may improve TNBC outcomes – medwire News

 

Commentary on Twitter

 


Systematic review: Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy

13 Jan, 2021 | 01:37h | UTC

Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy – Cochrane Library

Summary: Prevention of blood clots in non-hospitalised cancer patients receiving chemotherapy – Cochrane Library

 


Blueprint for cancer research: Critical gaps and opportunities

13 Jan, 2021 | 01:36h | UTC

Blueprint for cancer research: Critical gaps and opportunities – CA: A Cancer Journal for Clinicians

Commentary: American Cancer Society Report Identifies Critical Gaps and Research Opportunities for Improved Cancer Care – The ASCO Post

 


Randomized trial: Early interdisciplinary supportive care in patients with previously untreated metastatic esophagogastric cancer

12 Jan, 2021 | 01:36h | UTC

Early Interdisciplinary Supportive Care in Patients With Previously Untreated Metastatic Esophagogastric Cancer: A Phase III Randomized Controlled Trial – Journal of Clinical Oncology

 

Commentaries on Twitter

 


Randomized trial: Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) improve outcomes vs. traditional approach in locally advanced rectal cancer

12 Jan, 2021 | 01:12h | UTC

Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Meta-analysis: Total neoadjuvant therapy vs. standard therapy in locally advanced rectal cancer

12 Jan, 2021 | 01:10h | UTC

Total Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal Cancer: A Systematic Review and Meta-analysis – JAMA Network Open

Commentaries: Personalizing Treatment for Rectal Cancer: Total Neoadjuvant Therapy Is Leading the Way AND Total Neoadjuvant Therapy Improves Rectal Cancer Pathologic Response – Physician’s Weekly

Related meta-analysis (just published): Impact of Total Neoadjuvant Therapy vs. Standard Chemoradiotherapy in Locally Advanced Rectal Cancer: A Systematic Review and Meta-Analysis of Randomized Trials – Cancers

 

Commentary on Twitter

 


Study suggests the intensity of active surveillance in patients with rectal cancer managed by a watch-and-wait approach could be reduced if they maintain a complete clinical response within the first 3 years

12 Jan, 2021 | 01:11h | UTC

Conditional recurrence-free survival of clinical complete responders managed by watch and wait after neoadjuvant chemoradiotherapy for rectal cancer in the International Watch & Wait Database: a retrospective, international, multicentre registry study – The Lancet Oncology

Commentaries: Rectal cancer patients who “watch and wait” may only need few years of stringent follow-up – eCancer AND Intense rectal cancer surveillance may be reduced – MDedge

 


Meta-analysis: Lung cancer screening using low-dose computed tomography reduces lung cancer–specific mortality, albeit with a tradeoff of likely overdiagnosis

16 Dec, 2020 | 10:08h | UTC

Cancer-Specific Mortality, All-Cause Mortality, and Overdiagnosis in Lung Cancer Screening Trials: A Meta-Analysis – Annals of Family Medicine

 


Randomized trial: Extensive peritoneal lavage with saline after curative gastrectomy for gastric cancer does not benefit patients vs. surgery alone

16 Dec, 2020 | 09:55h | UTC

Extensive peritoneal lavage with saline after curative gastrectomy for gastric cancer (EXPEL): a multicentre randomised controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

Commentary: Peritoneal Lavage in Cancer Gastrectomy Is Not a Wash— Study found no survival benefit and more adverse events and deaths compared with standard surgery – MedPage Today

 

Commentary on Twitter

 


Brazilian Cardio-oncology Guideline – 2020

15 Dec, 2020 | 01:31h | UTC

Brazilian Cardio-oncology Guideline – 2020 – Arquivos Brasileiros de Cardiologia

 


Randomized trial: Among patients with advanced rectal cancer, short-course radiotherapy followed by chemotherapy before total mesorectal excision reduces disease-related treatment failure compared to standard treatment

15 Dec, 2020 | 01:29h | UTC

Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial – The Lancet Oncology

 

Commentary on Twitter

 


A nationwide study in Denmark showed a higher than expected risk of cardiac events in patients with cancer receiving immune checkpoint inhibitors

10 Dec, 2020 | 08:49h | UTC

The risk of cardiac events in patients receiving immune checkpoint inhibitors: a nationwide Danish study – European Heart Journal

Commentary: Cancer patients receiving immunotherapy drugs have a higher risk of heart problems – European Society of Cardiology

 


Short review: How to diagnose and manage radiation therapy cardiotoxicity

6 Dec, 2020 | 23:27h | UTC

How to Diagnose and Manage Radiation Cardiotoxicity – JACC: CardioOncology

 


Case series: Shedding of viable SARS-CoV-2 after immunosuppressive therapy for cancer

2 Dec, 2020 | 07:31h | UTC

Shedding of Viable SARS-CoV-2 after Immunosuppressive Therapy for Cancer – New England Journal of Medicine

 


Randomized trial: Colorectal cancer screening with repeated fecal immunochemical tests detects more colorectal cancer and advanced adenomas compared to screening sigmoidoscopy

25 Nov, 2020 | 09:05h | UTC

Colorectal cancer screening with repeated fecal immunochemical test versus sigmoidoscopy: baseline results from a randomized trial – Gastroenterology (link to abstract – $ for full-text)

 


Systematic review: Interventions for breathlessness in patients with advanced cancer

23 Nov, 2020 | 09:43h | UTC

Interventions for Breathlessness in Patients With Advanced Cancer – Agency for Healthcare Research and Quality

Full report: Interventions for breathlessness in patients with advanced cancer

Evidence Summary: Interventions for breathlessness in patients with advanced cancer

 


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