Oncology (all articles)
Breast Cancer Risk Genes — Association Analysis in More than 113,000 Women
10 Feb, 2021 | 01:07h | UTC
A population-based study of genes previously implicated in breast cancer
10 Feb, 2021 | 01:05h | UTCA Population-Based Study of Genes Previously Implicated in Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Intraoperative imaging technology to maximize extent of resection for glioma: a network meta‐analysis
8 Feb, 2021 | 20:11h | UTC
Guideline synopsis: Management of immunotherapy-related toxicities in patients treated with immune checkpoint inhibitor therapy
7 Feb, 2021 | 20:55h | UTCManagement of Immunotherapy-Related Toxicities in Patients Treated With Immune Checkpoint Inhibitor Therapy – JAMA (free for a limited period)
Audio Clinical Review: Management of Immunotherapy-Related Toxicities
Original guideline and other resources: NCCN Guidelines Insights: Management of Immunotherapy-Related Toxicities
Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
7 Feb, 2021 | 20:47h | UTCCommentaries: Breast cancer tops lung cancer as most diagnosed cancer in the world, new report says – CNN AND Breast Cancer Tops Lung Cancer for No. 1 Diagnosis Worldwide – Diagnostic Imaging
Related: Breast cancer now most common form of cancer: WHO taking action – World Health Organization
Commentary on Twitter
For the first time, female breast cancer has surpassed lung cancer as the most commonly diagnosed cancer in the world according to the latest @AmericanCancer & @IARCWHO report. https://t.co/SmX8czB4Wx #GlobalCancerStats🗺️#WorldCancerDay pic.twitter.com/IUMFkMUzx2
— CA: A Cancer Journal for Clinicians (@CACancerJournal) February 4, 2021
Clinical Cancer Advances 2021: ASCO’s Report on Progress Against Cancer
7 Feb, 2021 | 20:45h | UTCCommentary: ASCO Names Molecular Profiling in GI Cancers as Advance of the Year – OncLive
RCT: MRI-targeted biopsy safely reduces the need for biopsy in more than one-third of men at risk for prostate cancer
5 Feb, 2021 | 01:27h | UTCCommentary: Clinical trial: Using MRI for prostate cancer diagnosis equals or beats current standard – Ontario Institute for Cancer Research AND Another Win for MRI and Targeted Prostate Biopsy – MedPage Today (free registration required)
Related: MRI-Targeted, Systematic, and Combined Biopsy for Prostate Cancer Diagnosis – New England Journal of Medicine (study and commentaries) Negative Predictive Value of Multiparametric Magnetic Resonance Imaging in the Detection of Clinically Significant Prostate Cancer in the Prostate Imaging Reporting and Data System Era: A Systematic Review and Meta-analysis – European Urology AND Meta-Analysis: MRI plus Targeted Biopsy vs. Systematic Biopsy Alone for the Diagnosis of Prostate Cancer (studies and commentaries)
The Evolving Immunotherapy Landscape and the Epidemiology, Diagnosis, and Management of Cardiotoxicity: JACC: CardioOncology Primer
5 Feb, 2021 | 01:19h | UTC
Impact of COVID-19 on cancer care has been ‘profound’, warns UN health agency
5 Feb, 2021 | 01:38h | UTCImpact of COVID-19 on cancer care has been ‘profound’, warns UN health agency – UN News
Duration of adjuvant doublet chemotherapy (3 or 6 months) in patients with high-risk stage II colorectal cancer
3 Feb, 2021 | 01:10h | UTC
Meta-analysis: Risk of colorectal cancer and cancer related mortality after detection of low-risk or high-risk adenomas, compared with no adenoma, at index colonoscopy
3 Feb, 2021 | 01:20h | UTCRisk of Colorectal Cancer and Cancer Related Mortality After Detection of Low-risk or High-risk Adenomas, Compared With No Adenoma, at Index Colonoscopy: A Systematic Review And Meta-Analysis – Gastroenterology (link to abstract – $ for full-text)
Related studies: Colorectal Cancer Incidence and Mortality After Removal of Adenomas During Screening Colonoscopies – Gastroenterology AND Long-term Risk of Colorectal Cancer and Related Death After Adenoma Removal in a Large, Community-based Population – Gastroenterology (link to abstract – $ for full-text) AND Baseline Colonoscopy Findings Associated with 10-Year Outcomes in a Screening Cohort Undergoing Colonoscopy Surveillance – Gastroenterology (link to abstract – $ for full-text) AND Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence – JAMA
Related guideline: Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastroenterology
Small study shows feasibility of MRI-guided focused ultrasound ablation for localized intermediate-risk prostate cancer
3 Feb, 2021 | 01:09h | UTCCommentary: Study: MRI-guided ultrasound treats prostate cancer with few side effects – UPI
COVID-19 vaccine-linked adenopathies could mimic breast malignancies
2 Feb, 2021 | 01:17h | UTCCOVID-19 Vaccine-Linked Adenopathies Could Mimic Breast Malignancies – Diagnostic Imaging
Original Study: Unilateral axillary Adenopathy in the setting of COVID-19 vaccine – Clinical Imaging
Commentaries on Twitter
Important for radiologists to consider vaccine induced hyperplastic adenopathy in unilateral axillary adenopathy seen on #breastimaging post #COVID19Vaccine #COVID19
Read here https://t.co/7IizHgIzU0@NishiMehtaMD @KatiaDodelzon @KemiMDRad @WCMRadiology @BreastImaging
— Clinical Imaging (@CI_Journal) January 19, 2021
The COVID-19 vaccine may cause swollen lymph nodes that could be mistaken for breast malignancies. However, it's important not to postpone your vaccine or breast cancer screenings, researchers from @WCMRadiology and @WCMBreastCenter say. https://t.co/jLuVbA2rXL
— Weill Cornell Medicine (@WeillCornell) January 22, 2021
An analysis of contemporary oncology randomized clinical trials from low/middle-income vs. high-income countries
1 Feb, 2021 | 01:36h | UTCAn Analysis of Contemporary Oncology Randomized Clinical Trials From Low/Middle-Income vs High-Income Countries – JAMA Oncology (free for a limited period)
ASCO Guideline: Neoadjuvant chemotherapy, endocrine therapy, and targeted therapy for breast cancer
1 Feb, 2021 | 01:34h | UTC
Consensus statement recommends individualizing surveillance mammography for older patients after treatment for early-stage breast cancer
1 Feb, 2021 | 01:33h | UTCCommentaries: First Mammography Guidelines Released for Older Breast Cancer Survivors – Diagnostic Imaging AND New Surveillance Mammography Screening Guidelines Issued for Breast Cancer Survivors Aged 75 and Older – The ASCO Post
Radiation therapy for small-cell lung cancer: ASCO Guideline endorsement of an ASTRO Guideline
29 Jan, 2021 | 01:27h | UTC
Randomized trial: Prostate-only versus whole-pelvic radiation therapy in high-risk and very high-risk prostate cancer
28 Jan, 2021 | 01:09h | UTC
Commentary on Twitter
🚨 POP-RT P3 RCT in @ASCO_pubs
High-risk prostate cancer & pelvic LN risk ≥20% ➡️
-Prostate only
-Pelvic RTIG-IMRT w/ SIB
-50 Gy/25 fxn to Pelvis
-68 Gy to P+SV⬆️bFFS 95% v 81%
⬆️DFS ~90% v 77%
⬆️DMFS 96% v 89%
✅Low S/Ehttps://t.co/r6YjqWl8Cr#pcsm #radonc #oncoalert pic.twitter.com/d9EL02edcd— Mudit Chowdhary, MD (@DrChowdharyMD) January 27, 2021
ASCO Guideline Update: Initial management of noncastrate advanced, recurrent, or metastatic prostate cancer
28 Jan, 2021 | 01:17h | UTC
Preliminary study shows sitagliptin may prevent acute Graft-versus-Host Disease
26 Jan, 2021 | 00:35h | UTCDipeptidyl Peptidase 4 Inhibition for Prophylaxis of Acute Graft-versus-Host Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Sitagliptin promising addition for preventing acute GVHD – HealthDay
Cohort study: Aspirin linked to reduced risk of colon cancer if you start it before age 70
26 Jan, 2021 | 00:37h | UTCAspirin Use and Risk of Colorectal Cancer Among Older Adults – JAMA Oncology (free for a limited period)
Commentaries: Does aspirin lower colorectal cancer risk in older adults? It depends on when they start – Massachusetts General Hospital AND Aspirin Use Cuts CRC Risk in Those Initiating Use Before Age 70 – Physician’s Weekly
Randomized trial: In patients with colorectal peritoneal metastases, adding hyperthermic intraperitoneal chemotherapy to cytoreductive surgery does not improve survival and causes more frequent late complications
26 Jan, 2021 | 00:34h | UTCCytoreductive surgery plus hyperthermic intraperitoneal chemotherapy versus cytoreductive surgery alone for colorectal peritoneal metastases (PRODIGE 7): a multicentre, randomised, open-label, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)
Commentary on Twitter
https://twitter.com/TheLancetOncol/status/1351469448264351752
NCCN shares new guidance principles for vaccinating people with cancer against COVID-19
26 Jan, 2021 | 00:47h | UTCOriginal guideline: Preliminary Recommendations of the NCCN COVID-19 Vaccination Advisory Committee
Commentary: NCCN Shares New Recommendations for Vaccinating Patients With Cancer Against COVID-19 – The ASCO Post
Global variation in postoperative mortality and complications after cancer surgery: a multicenter, prospective cohort study in 82 countries
25 Jan, 2021 | 01:21h | UTCCommentary: Better post-surgical care would boost cancer survival chances – University of Birmingham
Commentary on Twitter (thread – Click for more)
https://twitter.com/ewenharrison/status/1352401851711418372
Randomized trial: First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in patients with non-small-cell lung cancer
25 Jan, 2021 | 01:12h | UTCFirst-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in patients with non-small-cell lung cancer (CheckMate 9LA): an international, randomised, open-label, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)
Commentary: First-line Nivolumab and Ipilimumab Plus Chemotherapy Improves OS in NSCLC – AJMC