Randomized trial: Prostate-only versus whole-pelvic radiation therapy in high-risk and very high-risk prostate cancer

Prostate-Only Versus Whole-Pelvic Radiation Therapy in High-Risk and Very High-Risk Prostate Cancer (POP-RT): Outcomes From Phase III Randomized Controlled Trial – Journal of Clinical Oncology

Commentary on Twitter

? POP-RT P3 RCT in @ASCO_pubs

High-risk prostate cancer & pelvic LN risk ≥20% ➡️
-Prostate only
-Pelvic RT

IG-IMRT w/ SIB
-50 Gy/25 fxn to Pelvis
-68 Gy to P+SV

⬆️bFFS 95% v 81%
⬆️DFS ~90% v 77%
⬆️DMFS 96% v 89%
✅Low S/Ehttps://t.co/r6YjqWl8Cr#pcsm #radonc #oncoalert pic.twitter.com/d9EL02edcd

— Mudit Chowdhary MD (@DrChowdharyMD) January 27, 2021