Oncology (all articles)
Systematic Review: Encephalitis induced by immune checkpoint inhibitors
16 Mar, 2021 | 01:36h | UTCEncephalitis Induced by Immune Checkpoint Inhibitors: A Systematic Review – JAMA Neurology
Perspective | New lung cancer screening guideline comes with many caveats
14 Mar, 2021 | 20:23h | UTCNew lung cancer screening guideline comes with many caveats – Lown Institute
Original Guideline: USPSTF Statement: begin screening for lung cancer at age 50 years instead of 55 years for patients at risk (article and commentaries)
Cohort study: Association of ablative radiation therapy with survival among patients with inoperable pancreatic cancer
14 Mar, 2021 | 20:09h | UTCAssociation of Ablative Radiation Therapy With Survival Among Patients With Inoperable Pancreatic Cancer – JAMA Oncology (free for a limited period)
Commentary on Twitter
Ablative RT to 98Gy biologically effective dose following multiagent induction therapy for locally advanced pancreatic cancer (LAPC) was safe & resulted in durable locoregional tumor control & favorable survival https://t.co/pLf52Tt6j0 #GICSM
— JAMA Oncology (@JAMAOnc) March 12, 2021
Guide to enhanced recovery for cancer patients undergoing breast surgery and reconstruction
14 Mar, 2021 | 20:01h | UTC
70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age
14 Mar, 2021 | 20:07h | UTC70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age – The Lancet Oncology (link to abstract – $ for full-text)
Meta-analysis of observational studies suggests better long-term oncologic outcomes with propofol-based total intravenous anesthesia compared to any volatile anesthesia
14 Mar, 2021 | 19:59h | UTC
Commentary on Twitter
🔴 Patients who receive propofol-based TIVA for cancer surgery are associated with better overall survival than volatile anesthesia though there is no statistically significant difference in cancer-free survival between propofol-based TIVA https://t.co/lJHxmcqjtB pic.twitter.com/7gYmZYZRij
— Anesthesia&Analgesia (@IARS_Journals) March 3, 2021
NCCN Best Practices Guidance: Management of COVID-19 Infection in Patients with Cancer
12 Mar, 2021 | 08:31h | UTC
USPSTF Statement: begin screening for lung cancer at age 50 years instead of 55 years for patients at risk
10 Mar, 2021 | 08:28h | UTCRecommendation Statement: Screening for Lung Cancer – US Preventive Services Task Force
Editorials: Broadened Eligibility for Lung Cancer Screening: Challenges and Uncertainty for Implementation and Equity – JAMA AND Expanded Access to Lung Cancer Screening—Implementing Wisely to Optimize Health – JAMA Network Open AND New USPSTF Guidelines for Lung Cancer Screening: Better but Not Enough – JAMA Surgery AND The 2021 US Preventive Services Task Force Recommendation on Lung Cancer Screening: The More Things Stay the Same… – JAMA Oncology
RCT: Secondary cytoreduction followed by chemotherapy vs. chemotherapy alone in platinum-sensitive relapsed ovarian cancer
10 Mar, 2021 | 08:18h | UTCSecondary cytoreduction followed by chemotherapy versus chemotherapy alone in platinum-sensitive relapsed ovarian cancer (SOC-1): a multicentre, open-label, randomised, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)
Commentary on Twitter
NEW online: SOC-1 trial—Secondary #cytoreduction followed by #chemotherapy versus chemotherapy alone in platinum-sensitive relapsed #ovariancancer #surgery #gyncsm https://t.co/cFq41Ck9EW pic.twitter.com/5gFsIGLBDA
— The Lancet Oncology (@TheLancetOncol) March 9, 2021
RCT: Primary tumor resection plus chemotherapy vs. chemotherapy alone for colorectal cancer patients with asymptomatic, synchronous unresectable metastases
7 Mar, 2021 | 19:23h | UTCOriginal study: No Survival Benefit to Primary Resection Before Chemo in Metastatic Colorectal Cancer – Medscape / Reuters
Primary tumor resection followed by chemotherapy in patients with metastatic colorectal cancer doesn't improve survival over chemotherapy alone https://t.co/iOYqjaABzi @JCOG_official #crcsm #JCO pic.twitter.com/RCj2OHEehH
— Journal of Clinical Oncology (@JCO_ASCO) March 5, 2021
New WHO/IAEA publication provides guidance on radiotherapy equipment to fight cancer
7 Mar, 2021 | 19:28h | UTCNews Release: New WHO/IAEA publication provides guidance on radiotherapy equipment to fight cancer – World Health Organization
Technical Document: Technical specifications of radiotherapy equipment for cancer treatment
🆕 guidance on the procurement of radiotherapy equipment released today in collaboration with @iaeaorg, aims to improve access to this life-saving #cancer treatment option that is still lacking in many parts of the world 🌎🌍🌏
👉 https://t.co/fnR0q3DDMq pic.twitter.com/21SHSaQGy7
— World Health Organization (WHO) (@WHO) March 5, 2021
Study: Cancer patients benefit from using automated device to manage their symptoms
7 Mar, 2021 | 19:21h | UTCOriginal study: Phase III Randomized Controlled Trial of eRAPID: eHealth Intervention During Chemotherapy – Journal of Clinical Oncology
Covid-19: Schedule breast screening before vaccine or 4 to 6 weeks after to avoid false positives, says guidance
5 Mar, 2021 | 08:35h | UTCRecommendations: Pharmacovigilance Evidence Review: The effect of COVID-19 vaccines on breast screening – Drug Safety Research Unit
Related: 2 Case Series and Guidance | Lymphadenopathy in COVID-19 Vaccine Recipients
ACG Clinical Guidelines: Start colorectal cancer screening at 45
5 Mar, 2021 | 08:31h | UTCACG Clinical Guidelines: Colorectal Cancer Screening 2021 – The American Journal of Gastroenterology
Related: USPSTF draft statement now recommends starting colorectal cancer screening at 45
Global patterns and trends in incidence and mortality of thyroid cancer in children and adolescents: a population-based study
5 Mar, 2021 | 08:10h | UTCGlobal patterns and trends in incidence and mortality of thyroid cancer in children and adolescents: a population-based study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: Global thyroid cancer overdiagnosis in children and adolescents – MDEdge (free registration required) AND Global Thyroid Cancer Overdiagnosis in Children and Adolescents – Medscape (free registration required)
Commentary on Twitter
New #IARCpaper shows the incidence of thyroid cancer in children & adolescents, a rare condition everywhere before 2000, has increased rapidly in recent years in many countries, & suggests overdiagnosis is likely to be the main driver of these increases https://t.co/1ct8iEJSty pic.twitter.com/JIjBBAyKNv
— IARC (@IARCWHO) January 20, 2021
RCT: Nivolumab plus Cabozantinib vs. Sunitinib for Advanced Renal-Cell Carcinoma
4 Mar, 2021 | 08:33h | UTCNivolumab plus Cabozantinib versus Sunitinib for Advanced Renal-Cell Carcinoma – New England Journal of Medicine (link to abstract – $ for full-text)
RCT: Effect of Blinatumomab vs. Chemotherapy in children with high-risk first-relapse B-Cell Acute Lymphoblastic Leukemia
3 Mar, 2021 | 08:19h | UTCEffect of Blinatumomab vs Chemotherapy on Event-Free Survival Among Children With High-risk First-Relapse B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial – JAMA (free for a limited period)
Related study: Effect of Postreinduction Therapy Consolidation With Blinatumomab vs Chemotherapy on Disease-Free Survival in Children, Adolescents, and Young Adults With First Relapse of B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Blinatumomab for Treatment of Children With High-risk Relapsed B-Cell Acute Lymphoblastic Leukemia – JAMA (free for a limited period)
Five-year outcomes from randomized, phase III trials: Nivolumab vs. Docetaxel in previously treated non–small-cell lung cancer
3 Mar, 2021 | 08:10h | UTC
Commentary on Twitter
At 5 years of follow up in CheckMate 017 and 057 trials, nivolumab continues to demonstrate a survival benefit vs docetaxel in patients with previously-treated advanced NSCLC https://t.co/oswZhdAPTW #JCO #lcsm #immunoonc pic.twitter.com/4FZJlfig99
— Journal of Clinical Oncology (@JCO_ASCO) February 9, 2021
RCT: Extended vs. limited pelvic lymph node dissection during radical prostatectomy for intermediate- and high-risk prostate cancer
3 Mar, 2021 | 08:05h | UTCExtended Versus Limited Pelvic Lymph Node Dissection During Radical Prostatectomy for Intermediate- and High-risk Prostate Cancer: Early Oncological Outcomes from a Randomized Phase 3 Trial – European Urology (link to abstract – $ for full-text)
Commentary: Extended pelvic lymph node dissection during RP does not appear beneficial – Urology Times
Commentary on Twitter
Extended Versus Limited Pelvic Lymph Node Dissection During Radical Prostatectomy for Intermediate- and High-risk Prostate Cancer: Early Oncological Outcomes from a Randomized Phase 3 Trial#VisualAbstract https://t.co/7fAFlKmfTf@jeanlestingi @qdtrinh @RafaelFCoelho2 pic.twitter.com/es53WpXBFR
— European Urology (@EUplatinum) December 10, 2020
M-A: Local salvage therapies after radiotherapy for prostate cancer
3 Mar, 2021 | 08:06h | UTCA Systematic Review and Meta-analysis of Local Salvage Therapies After Radiotherapy for Prostate Cancer (MASTER) – European Urology (link to abstract – $ for full-text)
Commentary on Twitter (thread – click for more)
Pleased to share the results of our "MASTER" systematic review and meta-analysis of local salvage therapies for radioreccurent PCa @EUPlatinum https://t.co/23hy1UtNm5
— Amar Kishan (@AmarUKishan) December 11, 2020
New report reviews methods for reducing waste, improving efficiency with expensive injectable medications
28 Feb, 2021 | 21:29h | UTCOriginal report: Medications in Single Dose Vials: Implications of Discarded Drugs (2021) – National Academies of Sciences, Engineering, and Medicine
Commentary on Twitter
"significant amounts of expensive injectable or infused drugs, distributed in single-dose vials, are discarded" but hard to quantify.
Medications in Single-Dose Vials and Implications of Discarded Injectable Drugs: A National Academies Report https://t.co/z3ebKGIcEg
— Suresh Nirody – snirody.eth (@snirody) February 26, 2021
2 Case Series and Guidance| Lymphadenopathy in COVID-19 Vaccine Recipients
28 Feb, 2021 | 21:42h | UTCCase series: Lymphadenopathy in COVID-19 Vaccine Recipients: Diagnostic Dilemma in Oncology Patients – Radiology
Related case series in women without cancer: Coronavirus Disease (COVID-19) Vaccination Associated Axillary Adenopathy: Imaging Findings and Follow-Up Recommendations in 23 Women – American Journal of Roentgenology
Related guidance 1: Multidisciplinary Recommendations Regarding Post-Vaccine Adenopathy and Radiologic Imaging: Radiology Scientific Expert Panel – Radiology
Related guidance 2: Mitigating the Impact of Coronavirus Disease (COVID-19) Vaccinations on Patients Undergoing Breast Imaging Examinations: A Pragmatic Approach – American Journal of Roentgenology AND Commentary: What to do when a mammogram shows swollen lymph nodes in women just vaccinated for COVID – Massachusetts General Hospital
Commentary: COVID-19 vaccine affects imaging results, researchers warn – AuntMinnie (free registration required)
RCT: Endoscopic surgery improves survival compared with intensity-modulated radiotherapy in resectable locally recurrent nasopharyngeal carcinoma
28 Feb, 2021 | 20:45h | UTC
CAR T-cell therapy produces deep, sustained remissions in patients with relapsed myeloma
26 Feb, 2021 | 08:31h | UTCOriginal study: Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma – New England Journal of Medicine
Integrated palliative and oncology care for patients receiving treatment for acute myeloid leukemia
26 Feb, 2021 | 08:25h | UTCOriginal article: Effectiveness of Integrated Palliative and Oncology Care for Patients With Acute Myeloid Leukemia: A Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)