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Oncology (all articles)

RCT | Rogaratinib vs. chemotherapy in patients with advancer urothelial carcinoma selected based on FGFR1/3 mRNA expression.

14 Dec, 2022 | 14:45h | UTC

FORT-1: Phase II/III Study of Rogaratinib Versus Chemotherapy in Patients With Locally Advanced or Metastatic Urothelial Carcinoma Selected Based on FGFR1/3 mRNA Expression – Journal of Clinical Oncology

Commentary: Rogaratinib Is Noninferior to Chemo in Pretreated FGFR1/3 mRNA+ Locally Advanced or Metastatic Urothelial Carcinoma – OncLive

 

Commentary on Twitter

 

Post-trial follow-up | Radiotherapy vs. surgery of the axilla after a positive sentinel node in breast cancer.

14 Dec, 2022 | 14:42h | UTC

Radiotherapy or Surgery of the Axilla After a Positive Sentinel Node in Breast Cancer: 10-Year Results of the Randomized Controlled EORTC 10981-22023 AMAROS Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)

Commentary: ART Preferred Over ALND in Sentinel Node-Positive Early Breast Cancer – Cancer Therapy Advisor

 

Prevention of device-related infections in patients with cancer: Current practice and future horizons.

13 Dec, 2022 | 14:30h | UTC

Prevention of device-related infections in patients with cancer: Current practice and future horizons – CA: A Cancer Journal for Clinicians

 

Review | Interventional gastroenterology in oncology.

12 Dec, 2022 | 12:46h | UTC

Interventional gastroenterology in oncology – CA: A Cancer Journal for Clinicians

 

RCT | Mepitel film for the prevention of acute radiation dermatitis in breast cancer.

12 Dec, 2022 | 12:40h | UTC

Mepitel Film for the Prevention of Acute Radiation Dermatitis in Breast Cancer: A Randomized Multicenter Open-Label Phase III Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)

Review | Palliative care for adolescents and young adults with advanced illness.

12 Dec, 2022 | 12:33h | UTC

Palliative care for adolescents and young adults with advanced illness: A scoping review – Palliative Medicine

 

Post-trial follow-up | Bursectomy vs. omentectomy alone for resectable gastric cancer.

12 Dec, 2022 | 12:26h | UTC

Five-year follow-up of a randomized clinical trial comparing bursectomy and omentectomy alone for resectable gastric cancer (JCOG1001) – British Journal of Surgery (link to abstract – $ for full-text)

 

RCT | Effects of prostate cancer screening with PSA and MRI followed by targeted biopsy only.

9 Dec, 2022 | 13:32h | UTC

Prostate Cancer Screening with PSA and MRI Followed by Targeted Biopsy Only – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: New prostate cancer diagnostic pathway paves way for general screening – University of Gothenburg

Commentary: MRI-Targeted Biopsy Beneficial for Men With Elevated PSA – HealthDay

 

Commentary on Twitter

 

Consensus Paper | Evaluation and management of cancer patients presenting with acute cardiovascular diseases.

9 Dec, 2022 | 13:28h | UTC

Evaluation and management of cancer patients presenting with acute cardiovascular disease: a Clinical Consensus Statement of the Acute CardioVascular Care Association (ACVC) and the ESC council of Cardio-Oncology—part 2: acute heart failure, acute myocardial diseases, acute venous thromboembolic diseases, and acute arrhythmias – European Heart Journal. Acute Cardiovascular Care

See also: Evaluation and management of cancer patients presenting with acute cardiovascular disease: a Consensus Document of the Acute CardioVascular Care (ACVC) association and the ESC council of Cardio-Oncology—Part 1: acute coronary syndromes and acute pericardial diseases – European Heart Journal. Acute Cardiovascular Care

Related:

The ‘Ten Commandments’ for the 2022 European Society of Cardiology guidelines on cardio-oncology.

#ESCCongress | 2022 ESC Guidelines on cardio-oncology.

Management of cardiac disease in cancer patients throughout oncological treatment: ESMO consensus recommendations – Annals of Oncology

Cardio-Oncology: Vascular and Metabolic Perspectives: A Scientific Statement from the American Heart Association – Circulation

Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline

Cardio-Onco-Hematology in Clinical Practice. Position Paper and Recommendations – Revista Espanola de Cardiologia

Evaluation and management of cancer patients presenting with acute cardiovascular disease: a Consensus Document of the Acute CardioVascular Care (ACVC) association and the ESC council of Cardio-Oncology—Part 1: acute coronary syndromes and acute pericardial diseases – European Heart Journal. Acute Cardiovascular Care

Brazilian Cardio-oncology Guideline – 2020 – Arquivos Brasileiros de Cardiologia

AHA Statement: Cardio-Oncology Rehabilitation to Manage Cardiovascular Outcomes in Cancer Patients and Survivors

 

RCT | Oncological outcome of short-term, intensive chemoresection with mitomycin in nonmuscle invasive bladder cancer.

9 Dec, 2022 | 13:15h | UTC

DaBlaCa-13 Study: Oncological Outcome of Short-Term, Intensive Chemoresection With Mitomycin in Nonmuscle Invasive Bladder Cancer: Primary Outcome of a Randomized Controlled Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)

Commentary: Chemoresection Reduces Need for Surgery in Nonmuscle Invasive Bladder Cancer – Cancer Therapy Advisor

 

Commentary on Twitter

 

RCT | Olaparib with or without Cediranib for metastatic castration-resistant prostate cancer.

9 Dec, 2022 | 13:14h | UTC

Randomized Trial of Olaparib With or Without Cediranib for Metastatic Castration-Resistant Prostate Cancer: The Results From National Cancer Institute 9984 – Journal of Clinical Oncology

Commentary: Olaparib Plus Cediranib for mCRPC Lowers Radiographic Progression Risk – Renal & Urology News

 

Commentary on Twitter

 

Endocervical sampling in women with suspected cervical neoplasia: a meta-analysis of diagnostic test accuracy studies.

9 Dec, 2022 | 13:12h | UTC

Endocervical sampling in women with suspected cervical neoplasia: a systematic review and meta-analysis of diagnostic test accuracy studies – American Journal of Obstetrics & Gynecology

 

RCT | Tumor-infiltrating lymphocyte therapy vs. Ipilimumab in advanced melanoma.

8 Dec, 2022 | 12:51h | UTC

Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Patient’s own immune cells effective as living medicine for melanoma – Netherlands Cancer Institute

 

RCT | Trastuzumab deruxtecan vs. trastuzumab emtansine in patients with HER2-positive metastatic breast cancer.

8 Dec, 2022 | 12:49h | UTC

Trastuzumab deruxtecan versus trastuzumab emtansine in patients with HER2-positive metastatic breast cancer: updated results from DESTINY-Breast03, a randomised, open-label, phase 3 trial – The Lancet

 

ASCO Guideline | Use of opioids for adults with pain from cancer or cancer treatment.

7 Dec, 2022 | 14:32h | UTC

Use of Opioids for Adults With Pain From Cancer or Cancer Treatment: ASCO Guideline – Journal of Clinical Oncology

 

German Guidelines on Sarcoma of the Uterus.

6 Dec, 2022 | 13:50h | UTC

Sarcoma of the Uterus. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/074, April 2021) – Geburtshilfe und Frauenheilkunde 

Cohort Study | Lobectomy vs. total thyroidectomy for intermediate-risk papillary thyroid carcinoma with lymph node metastasis.

6 Dec, 2022 | 13:41h | UTC

Comparison of Lobectomy vs Total Thyroidectomy for Intermediate-Risk Papillary Thyroid Carcinoma With Lymph Node Metastasis – JAMA Surgery (free for a limited period)

Invited Commentary: Is Lobectomy as Effective as Total Thyroidectomy in Treating Patients With Intermediate-Risk Papillary Thyroid Carcinoma With Lateral Lymph Node Metastasis? – JAMA Surgery (free for a limited period)

 

Commentary on Twitter

 

Perspective | The coming decade in precision oncology: six riddles.

4 Dec, 2022 | 23:59h | UTC

The coming decade in precision oncology: six riddles – Nature Reviews Cancer

 

Commentary on Twitter

 

Phase 2b RCT | Cannabidiol oil failed to relieve symptoms in advanced cancer.

1 Dec, 2022 | 14:04h | UTC

Phase IIb Randomized, Placebo-Controlled, Dose-Escalating, Double-Blind Study of Cannabidiol Oil for the Relief of Symptoms in Advanced Cancer (MedCan1-CBD) – Journal of Clinical Oncology

Commentary: Cannabis oil failed to improve pain or quality of life in palliative care cancer patients, study shows – The Guardian

Related:

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Systematic Review: Cannabis-based products for chronic pain.

Podcast: #338 LIVE! Medical Cannabis: Is it still dope? – The Curbsiders

Medicinal Cannabis for Chronic Pain: The Bermuda Triangle of Low Quality Studies, Countless Meta-analyses and Conflicting Recommendations – European Journal of Pain

RCT: Effect of medical marijuana card ownership on pain, insomnia, and affective disorder symptoms in adults. 

Cohort Study: Long-term cannabis use is associated with cognitive deficits and smaller hippocampal volume in midlife. 

AHA Scientific Statement | How does cannabis use affect brain health? Caution advised, more research needed.

M-A: Birth outcomes of neonates exposed to marijuana in utero. 

Cannabis-related allergies: an international overview and consensus recommendations.

Review: Cannabis-based medicines and medical cannabis for chronic neuropathic pain.

Cannabinoid metabolites as inhibitors of major hepatic CYP450 enzymes, with implications for cannabis-drug interactions.

The International Cannabis Toolkit (iCannToolkit): a multidisciplinary expert consensus on minimum standards for measuring cannabis use.

Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.

Guideline: Medical cannabis or cannabinoids for chronic pain.

Cannabis and Cannabinoid Analgesia position statement – “Due to the lack of high-quality clinical evidence, the IASP does not currently endorse general use of cannabis and cannabinoids for pain relief.”

NICE Guideline: Cannabis-Based Medicinal Products

Consensus recommendations for perioperative management of cannabis and cannabinoid-based medicine users

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Short Review: Drug Interactions with Cannabinoids

Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain

Review: Considerations for cannabinoids in perioperative care by anesthesiologists.

Review: Cannabis-based Medicines and the Perioperative Physician

Study: Cannabis Use Disorder May Increase the Risk of Cardiovascular Events in Major Elective Surgeries

Perspective: If You Smoke Pot, Your Anesthesiologist Needs To Know

Perioperative Care of Cannabis Users: A Comprehensive Review of Pharmacological and Anesthetic Considerations

 

The ‘Ten Commandments’ for the 2022 European Society of Cardiology guidelines on cardio-oncology.

29 Nov, 2022 | 14:13h | UTC

The ‘Ten Commandments’ for the 2022 European Society of Cardiology guidelines on cardio-oncology – European Journal of Cardiology

Original guideline: #ESCCongress | 2022 ESC Guidelines on cardio-oncology.

 

Skin cancer in solid organ transplant recipients: a review for the non-dermatologist.

27 Nov, 2022 | 22:02h | UTC

Skin Cancer in Solid Organ Transplant Recipients: A Review for the Nondermatologist – Mayo Clinic Proceedings

 

Brief Review | Ischemic stroke in patients with malignancy.

27 Nov, 2022 | 22:01h | UTC

Ischemic Stroke in Patients With Malignancy – Mayo Clinic Proceedings

 

Case–control study | GLP-1 receptor agonists linked to increased risk of thyroid cancer.

25 Nov, 2022 | 12:42h | UTC

GLP-1 Receptor Agonists and the Risk of Thyroid Cancer – Diabetes Care (link to abstract – $ for full-text)

Commentary: GLP-1 receptor agonists associated with thyroid cancer – ACP Internist

 

Guideline | Screening and assessment of cancer-related fatigue.

23 Nov, 2022 | 13:58h | UTC

Screening and Assessment of Cancer-Related Fatigue: A Clinical Practice Guideline for Health Care Providers – Physical Therapy

Related: Management of cancer-related fatigue in Taiwan: an evidence-based consensus for screening, assessment and treatment – Japanese Journal of Clinical Oncology

 

RCT | Effects of a physical exercise intervention during vs. after chemotherapy to improve cardiorespiratory fitness.

23 Nov, 2022 | 14:01h | UTC

Optimal Timing of a Physical Exercise Intervention to Improve Cardiorespiratory Fitness: During or After Chemotherapy – JACC: CardioOncology

Editorial: Inclusion of Exercise in Cancer Treatment Planning: When Is the Right Time? – JACC: CardioOncology

Commentary: Exercise Intervention During Chemotherapy Beneficial – HealthDay

 

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