Neurology
Case Series: Recurrent Glioblastoma Treated with Recombinant Poliovirus
29 Jun, 2018 | 02:50h | UTCRecurrent Glioblastoma Treated with Recombinant Poliovirus – New England Journal of Medicine (free for a limited period)
Editorial: Exploiting Viruses to Treat Diseases (free for a limited period)
Commentaries: Doctors Try Genetically Modified Poliovirus As Experimental Brain Cancer Treatment – NPR (free) AND Poliovirus therapy shows early promise in patients with aggressive brain cancer but questions linger – STAT (free)
Systematic Review: Donepezil for Dementia Due to Alzheimer’s Disease
29 Jun, 2018 | 02:36h | UTCDonepezil for dementia due to Alzheimer’s disease – Cochrane Library (free)
Summary: Donepezil for people with dementia due to Alzheimer’s disease – Cochrane Library (free)
Guideline: Advance Care Planning in Dementia
29 Jun, 2018 | 02:30h | UTCRelated: New Document for Patients: Advanced Health Directive for Dementia (free document and commentaries) AND Alzheimer’s? Your Paperwork May Not Be in Order – The New York Times (free)
Systematic Review: Non-pharmacological Interventions to Improve Nighttime Sleep Among Residents of Long-Term Care Settings
29 Jun, 2018 | 02:10h | UTC
Guideline: Management of Idiopathic Intracranial Hypertension
29 Jun, 2018 | 02:06h | UTC
NICE Guideline: Dementia
22 Jun, 2018 | 02:34h | UTC
Pharmacoepidemiological Study: Association of Antidepressant Use With Drug-Related Extrapyramidal Symptoms
22 Jun, 2018 | 02:28h | UTCAssociation of Antidepressant Use With Drug-Related Extrapyramidal Symptoms: A Pharmacoepidemiological Study – Journal of Clinical Psychopharmacology (link to abstract – $ for full-text)
Commentaries: Incidence of Extrapyramidal Symptoms Higher With Certain Antidepressants – MPR (free) AND Antidepressants tied to Parkinson’s-like symptoms – Univadis (free registration required)
“Observational study: Incidence of EPSs with antidepressants. RRs: duloxetine, 5.68; mirtazapine, 3.78; citalopram, 3.47; escitalopram, 3.23; paroxetine, 3.07; sertraline, 2.57; venlafaxine, 2.37; bupropion, 2.31; and fluoxetine, 2.03 (all significant)” (via @psychopharmacol see Tweet)
Perspective: Sleep Disorders Associated With Alzheimer’s Disease
22 Jun, 2018 | 02:17h | UTCSleep Disorders Associated With Alzheimer’s Disease: A Perspective – Frontiers in Neuroscience (free)
Position Paper: Treatment of Nightmare Disorder in Adults
18 Jun, 2018 | 23:01h | UTCCommentary: New position paper recommends treatment options for nightmare disorder in adults – American Academy of Sleep Medicine, via EurekAlert (free)
Report: Current Endovascular Strategies for Cerebral Venous Thrombosis
18 Jun, 2018 | 09:15h | UTC
Guideline: Efficacy and Tolerability of the New Antiepileptic Drugs
18 Jun, 2018 | 00:21h | UTCPractice guideline update summary: Efficacy and tolerability of the new antiepileptic drugs – American Academy of Neurology and the American Epilepsy Society
Part I: Treatment of new-onset epilepsy (free PDF)
Part II: Treatment-resistant epilepsy (free PDF)
Commentary: New Epilepsy Guidelines Shed Light on Explosion of New Drugs – MedPage Today (free registration required)
Cohort Study: High Blood Pressure in 50-year-olds Associated with Higher Risk of Dementia
15 Jun, 2018 | 02:13h | UTCCommentaries: Dementia risk increased in 50-year-olds with blood pressure below hypertension threshold – European Society of Cardiology, via EurekAlert (free) AND Blood pressure below treatable threshold linked to heightened dementia risk – OnMedica (free) AND Studies: Higher blood pressure increases risk for dementia – UPI (free) AND High Blood Pressure at Age 50 Tied to Dementia Risk – The New York Times (10 articles per month are free) AND Dementia risk to 50-year-olds with raised blood pressure – study – The Guardian (free)
Review: Antiepileptic Drugs in Critically Ill Patients
15 Jun, 2018 | 02:05h | UTCAntiepileptic drugs in critically ill patients – Critical Care (free)
Randomized Trial: Antipsychotic Treatment of Very Late-onset Schizophrenia-like Psychosis
15 Jun, 2018 | 00:55h | UTCCommentaries: Very late-onset schizophrenia-like psychosis: positive findings but questions remain unanswered – The Lancet Psychiatry (free) AND Low-Dose Antipsychotic Effective in Late-Onset Psychosis – Medscape (free registration required) AND Low-dose amisulpride effective for late-onset psychosis – Healio (free registration required)
Randomized Trial Continuous Low-dose Antibiotic Prophylaxis to Prevent UTI in Adults who Perform Clean Intermittent Self-catheterization
7 Jun, 2018 | 02:52h | UTC“The results of this large randomised trial, conducted in accordance with best practice, demonstrate clear benefit for antibiotic prophylaxis in terms of reducing the frequency of UTI for people carrying out CISC”.
Systematic Review: Exercise for Cognitive Brain Health in Aging
7 Jun, 2018 | 02:43h | UTCExercise for cognitive brain health in aging: A systematic review for an evaluation of dose – Neurology Clinical Practice (link to abstract – $ for full-text)
Commentary: How Much Exercise Is Needed to Help Improve Thinking Skills? – American Academy of Neurology, via NewsWise (free) AND Exercise regimen can maintain cognition in older adults, researchers say – UPI (free) AND 1-Hour Exercise, 3 Times a Week Boosts Cognition in Older Adults – MedPage Today (free registration required)
Current Concepts in Diagnosis and Treatment of Functional Neurological Disorders
7 Jun, 2018 | 02:37h | UTCCurrent Concepts in Diagnosis and Treatment of Functional Neurological Disorders – JAMA Neurology (free for a limited period)
Review: Perimesencephalic Hemorrhage
6 Jun, 2018 | 21:35h | UTCPerimesencephalic Hemorrhage: A Review of Epidemiology, Risk Factors, Presumed Cause, Clinical Course, and Outcome – Stroke (free for a limited period)
Review: Management of Chronic Inflammatory Demyelinating Polyradiculoneuropathy
6 Jun, 2018 | 21:26h | UTC
Systematic Review: Effects of Physical Exercise on Cognitive Function in Parkinson’s Disease
29 May, 2018 | 18:36h | UTC
Randomized Trial: New Treatment for Prevention of Episodic Migraine Assessed
29 May, 2018 | 18:30h | UTCEffect of Fremanezumab Compared With Placebo for Prevention of Episodic Migraine: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: Fremanezumab effective in preventing episodic migraine – 2 Minute Medicine (free)
“Among patients with episodic migraine in whom multiple medication classes had not previously failed, subcutaneous fremanezumab, compared with placebo, resulted in a statistically significant 1.3- to 1.5-day reduction in the mean number of monthly migraine days over a 12-week period”. (from JAMA)
“The small effect size in terms of reduction in number of days with migraine dampens enthusiasm for this medication, though without head-to-head comparison against other prophylactics, this is hard to assess” (from 2 Minute Medicine)
Cohort Study: Vascular Risk Interacts with β-Amyloid Burden in the Progression of Cognitive Decline
28 May, 2018 | 12:44h | UTCInteractive Associations of Vascular Risk and β-Amyloid Burden With Cognitive Decline in Clinically Normal Elderly Individuals: Findings From the Harvard Aging Brain Study – JAMA Neurology (free for a limited period)
Commentaries: Vascular risk interacts with amyloid levels to increase age-related cognitive decline – Massachusetts General Hospital, via ScienceDaily (free) AND Bad Synergy—Together, Vascular Problems and Aβ Hasten Memory Slippage – AlzForum (free) AND Combo of vascular risk, brain amyloid could quicken mental decline – Cardiovascular Business (free)
Cohort Study: Inflammatory Bowel Disease Patients Have Higher Risk of Parkinson’s disease
24 May, 2018 | 22:37h | UTCCommentary: Inflammatory bowel disease may raise Parkinson’s risk – Medical News Today (free)
Review: Updates in Refractory Status Epilepticus
24 May, 2018 | 22:22h | UTCUpdates in Refractory Status Epilepticus – Critical Care Research and Practice (free)
Source: Critical Care Reviews Newsletter
Retrospective Cohort: Atrial Fibrillation Burden and Risk of Stroke in Adults with Paroxysmal Atrial Fibrillation
23 May, 2018 | 12:48h | UTCCommentaries: Atrial Fibrillation Burden and Stroke Risk – American College of Cardiology (free) AND Greater burden of atrial fibrillation linked to higher stroke risk – Kaiser Permanente, via EurekAlert (free)