Neurology
AAN Guideline: Disorders of Consciousness
11 Aug, 2018 | 03:14h | UTCRelated: Ethical, palliative, and policy considerations in disorders of consciousness – Neurology (free PDF) AND Comprehensive systematic review update summary: Disorders of consciousness – Neurology (free PDF)
Commentaries: New Guideline Released for Managing Vegetative and Minimally Conscious States – American Academy of Neurology, via NewsWise (free) AND Groups Issue New Disorders of Consciousness Guidelines – MedPage Today (free registration required)
ESMO Guideline: Delirium in Adult Cancer Patients
11 Aug, 2018 | 02:12h | UTCDelirium in adult cancer patients: ESMO Clinical Practice Guidelines – Annals of Oncology (free)
Cohort Study: Association of Orthostatic Hypotension with Cognitive Decline
3 Aug, 2018 | 11:40h | UTCAssociation of orthostatic hypotension with incident dementia, stroke, and cognitive decline – Neurology (link to abstract – $ for full-text)
Commentary: People who frequently feel dizzy on standing ‘at future risk of dementia’ – NHS Choices (free)
Related Research: Orthostatic hypotension and symptomatic subclinical orthostatic hypotension increase risk of cognitive impairment: an integrated evidence review and analysis of a large older adult hypertensive cohort – European Heart Journal (free)
Study: Soccer Heading May Be Riskier for Female Players
3 Aug, 2018 | 11:37h | UTCMRI-defined White Matter Microstructural Alteration Associated with Soccer Heading Is More Extensive in Women than Men – Radiology (link to abstract – $ for full-text)
Commentaries: Soccer Heading May Be Riskier for Female Players – RSNA (free) AND Heading May Be Riskier For Female Soccer Players Than Males – NPR (free)
Cohort Study: Alcohol Consumption and Risk of Dementia
3 Aug, 2018 | 00:18h | UTCAlcohol consumption and risk of dementia: 23 year follow-up of Whitehall II cohort study – The BMJ (free)
Editorial: Relation between alcohol consumption in midlife and dementia in late life (free)
Commentaries: Expert reaction to long term abstinence and heavy drinking associated with dementia – Science Media Centre (free) AND Middle-aged non-drinkers may have ‘higher risk’ of dementia – The Guardian (free)
Opinion: Intensive Blood pressure Control and ‘Dementia’
26 Jul, 2018 | 20:23h | UTCSee also: No, A Big NIH Trial Did Not Show That Lowering Blood Pressure Will Prevent Dementia – Cardiobrief (free)
Systematic Review: Mirror Therapy for Improving Motor Function After Stroke
26 Jul, 2018 | 20:21h | UTCMirror therapy for improving motor function after stroke – Cochrane Library (link to abstract – $ for full-text)
Summary: Mirror therapy for improving movement after stroke – Cochrane Library (free)
Guideline: PFO closure vs. Antiplatelet Therapy vs. Anticoagulation for Management of Cryptogenic stroke
26 Jul, 2018 | 18:40h | UTCRapid Recommendations: Patent foramen ovale closure, antiplatelet therapy or anticoagulation therapy alone for management of cryptogenic stroke? A clinical practice guideline – The BMJ (free)
CDC: Subjective Cognitive Decline Common Among Adults Aged ≥45 Years
26 Jul, 2018 | 18:38h | UTCCommentary: CDC: 1 in 9 U.S. adults over 45 reports memory problems – UPI (free)
Guideline: Acute Stroke Management
26 Jul, 2018 | 18:09h | UTC
Guideline: Acute Stroke Management During Pregnancy
26 Jul, 2018 | 18:08h | UTC
Review: Pediatric Multiple Sclerosis
26 Jul, 2018 | 17:43h | UTCPediatric multiple sclerosis: a review – BMC Neurology (free)
Randomized Trial: Alteplase vs Aspirin for Patients with Acute Ischemic Stroke and Minor Nondisabling Neurologic Deficits
13 Jul, 2018 | 02:58h | UTCEffect of Alteplase vs Aspirin on Functional Outcome for Patients With Acute Ischemic Stroke and Minor Nondisabling Neurologic Deficits: The PRISMS Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Stopping the Alteplase Indication Creep – Emergency Medicine Literature of Note (free) AND Alteplase unlikely to reduce disability after mild stroke without disabling deficits – 2 Minute Medicine (free) AND Lytic No Better Than Aspirin for Mild Ischemic Stroke – MedPage Today (free registration required)
NICE Guideline: Brain Tumors (Primary) and Brain Metastases in Adults
13 Jul, 2018 | 02:57h | UTC
FDA Safety Alert: Warnings for Fluoroquinolones on Risks of Mental Health and Low Blood Sugar Adverse Reactions
13 Jul, 2018 | 02:50h | UTCNews Release: FDA updates warnings for fluoroquinolone antibiotics on risks of mental health and low blood sugar adverse reactions – U.S. Food and Drug Administration (free)
Commentaries: FDA Strengthens Warnings for Fluoroquinolone Antibiotics – MPR (free) AND FDA Announces Labeling Changes for Fluoroquinolones Due to Mental Health AEs, Blood Sugar Disturbances – MD Magazine (free)
Amyotrophic Lateral Sclerosis: An Update for 2018
13 Jul, 2018 | 01:40h | UTCAmyotrophic Lateral Sclerosis: An Update for 2018 – Mayo Clinic Proceedings (free)
Refractory Status Epilepticus: Pearls and Pitfalls for the Resuscitation Room
13 Jul, 2018 | 01:39h | UTCRefractory Status Epilepticus: Pearls and Pitfalls for the Resuscitation Room – emDocs (free)
Review: ICU Delirium ― A Diagnostic and Therapeutic Challenge in the Intensive Care Unit
13 Jul, 2018 | 01:18h | UTCSource: Critical Care Reviews Newsletter
Randomized Trial: Antibiotic Prophylaxis for Patients with Neurogenic Bladder and Repeated Urinary Tract Infections
6 Jul, 2018 | 09:47h | UTCInvited Commentary: Preventing urinary tract infections in patients with neurogenic bladder (free)
Meta-Analysis: Anticonvulsants in the Treatment of Low Back Pain and Lumbar Radicular Pain
6 Jul, 2018 | 09:37h | UTCCommentaries: Class of drugs used as alternative to opioids for back pain are ineffective, have potentially serious side effects: report – The Globe and Mail (free) AND Anticonvulsant drugs ineffective for low back pain and can cause harm, despite increased prescribing – CMAJ, via EurekAlert (free)
Related Meta-Analysis: Benefits and safety of gabapentinoids in chronic low back pain (free research and commentaries)
Cohort Study: Retinal Nerve Fiber Layer Thinning and Future Cognitive Decline
29 Jun, 2018 | 02:53h | UTCAssociation of Retinal Nerve Fiber Layer Thinning With Current and Future Cognitive Decline: A Study Using Optical Coherence Tomography – JAMA Neurology (free for a limited period)
Commentaries: Eye Sign of Dementia Risk? Thinning of Retinal Nerve Fiber Layer – MedicalResearch.com (free) AND Are the Eyes Windows to Early Dementia? – MedPage Today (free registration required)
“A thinner Retinal Nerve Fiber Layer is associated with worse cognitive function in individuals without a neurodegenerative disease as well as greater likelihood of future cognitive decline”.
Case Series: Recurrent Glioblastoma Treated with Recombinant Poliovirus
29 Jun, 2018 | 02:50h | UTCRecurrent Glioblastoma Treated with Recombinant Poliovirus – New England Journal of Medicine (free for a limited period)
Editorial: Exploiting Viruses to Treat Diseases (free for a limited period)
Commentaries: Doctors Try Genetically Modified Poliovirus As Experimental Brain Cancer Treatment – NPR (free) AND Poliovirus therapy shows early promise in patients with aggressive brain cancer but questions linger – STAT (free)
Systematic Review: Donepezil for Dementia Due to Alzheimer’s Disease
29 Jun, 2018 | 02:36h | UTCDonepezil for dementia due to Alzheimer’s disease – Cochrane Library (free)
Summary: Donepezil for people with dementia due to Alzheimer’s disease – Cochrane Library (free)
Guideline: Advance Care Planning in Dementia
29 Jun, 2018 | 02:30h | UTCRelated: New Document for Patients: Advanced Health Directive for Dementia (free document and commentaries) AND Alzheimer’s? Your Paperwork May Not Be in Order – The New York Times (free)
Systematic Review: Non-pharmacological Interventions to Improve Nighttime Sleep Among Residents of Long-Term Care Settings
29 Jun, 2018 | 02:10h | UTC