Neurology
Two Antiplatelet Drugs may Prevent Further Strokes but Increase Major Bleeds
5 Oct, 2018 | 02:24h | UTCTwo antiplatelet drugs may prevent further strokes but increase major bleeds – NIHR Signal (free)
Original Article: Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA – New England Journal of Medicine (link to abstract – $ for full-text)
Clinical Guide: Neuro-Ophthalmology at the Bedside
5 Oct, 2018 | 02:02h | UTCNeuro-Ophthalmology at the bedside: A clinical guide – Journal of Neurosciences in Rural Practice (free)
Standards for Neurologic Critical Care Units
5 Oct, 2018 | 01:42h | UTC
Randomized Trial: Insomnia Symptoms Iimprove with Online Insomnia Program
28 Sep, 2018 | 00:59h | UTCEffect of Digital Cognitive Behavioral Therapy for Insomnia on Health, Psychological Well-being, and Sleep-Related Quality of Life: A Randomized Clinical Trial – JAMA Psychiatry (free for a limited period) (via @EricTopol)
Commentary: Insomnia symptoms, overall health improve with online insomnia program – Northwestern University (free)
Systematic Review: Modifying the Consistency of Food and Fluids for Swallowing Difficulties in Dementia
28 Sep, 2018 | 00:57h | UTCModifying the consistency of food and fluids for swallowing difficulties in dementia – Cochrane Library (free for a limited period)
Summary: Modifying the consistency of food and fluids for swallowing difficulties in dementia (free)
“We are uncertain about the immediate and long-term effects of modifying the consistency of fluid for swallowing difficulties in dementia”
Study: Recovery of Walking after Complete Spinal Cord Injury
27 Sep, 2018 | 23:06h | UTCCommentaries: Technology and therapy help individuals with chronic spinal cord injuries take steps – University of Louisville (free) AND Epidural Stimulation Helps Patients Walk After Total Paralysis – MedPage Today (free registration required) AND Paralyzed Patients Able to Walk Following Epidural Stimulation, Intense Rehab – Physician’s First Watch (free)
Consensus: Targeted Temperature Management in Patients with Intracerebral Hemorrhage, Subarachnoid Hemorrhage, or Acute Ischemic Stroke
27 Sep, 2018 | 22:46h | UTCSource: Critical Care Reviews Newsletter
Podcast: Geriatric Depression
27 Sep, 2018 | 22:45h | UTC#115 Geriatric Depression – The Curbsiders Internal Medicine Podcast (free)
Summary: #115 Geriatric Depression: Diagnosis, Antidepressants, and More (free)
Study: Alzheimer’s Disease and Related Dementias will Double by 2060
27 Sep, 2018 | 22:31h | UTCRacial and ethnic estimates of Alzheimer’s disease and related dementias in the United States (2015–2060) in adults aged ≥65 years – Alzheimer’s & Dementia (free for a limited period)
Commentaries: Alzheimer’s and dementia cases will double by 2060 -HealthExec (free) AND Alzheimer’s Burden Projected to Double by 2060 – Physician’s First Watch (free) AND Alzheimer’s Disease Burden to Double by 2060 – MedPage Today (free registration required)
Cohort Study: Risk of Dementia by Age, Sex and APOE Genotype
27 Sep, 2018 | 22:20h | UTC
Guideline: Hyperacute Endovascular Treatment Workflow to Reduce Door-to-Reperfusion Time
27 Sep, 2018 | 22:18h | UTC
Cohort Study: Are Noise and Air Pollution Related to the Incidence of Dementia?
21 Sep, 2018 | 01:47h | UTCCommentaries: Air pollution linked to dementia risk – NHS Choices (free) AND Expert reaction to air pollution and risk of dementia – Science Media Centre (free) AND Air pollution may be linked to heightened dementia risk – OnMedica (free) AND Is air pollution tied to higher dementia risk? – CNN (free)
Review: Optimizing Medications in Older Adults with Cognitive Impairment
20 Sep, 2018 | 19:23h | UTC
CDC Report: Prevalence of Chronic Pain and High-Impact Chronic Pain Among Adults
20 Sep, 2018 | 19:18h | UTCCommentaries: Chronic Pain Affects 20% of Americans, CDC Reports – MedPage Today (free registration required) AND CDC: About 1 in 5 US Adults Have Chronic Pain – MPR (free) AND One-fifth of American adults experience chronic pain, CDC estimates – CNBC (free)
How Well do You Know your Anticholinergic (Antimuscarinic) Drugs?
14 Sep, 2018 | 01:56h | UTCHow well do you know your anticholinergic (antimuscarinic) drugs? – Therapeutics Initiative (free)
Randomized Trial: Preventing Cognitive Decline in Individuals with Mild Cognitive Impairment
14 Sep, 2018 | 01:36h | UTCPreventing Cognitive Decline in Black Individuals With Mild Cognitive Impairment: A Randomized Clinical Trial – JAMA Neurology (free for a limited period)
Commentary: Study provides evidence to prevent memory decline in older blacks with mild cognitive impairment – News Medical (free) AND Novel Intervention Markedly Slows Cognitive Decline in MCI – Medscape (free registration required)
CDC Guideline: Diagnosis and Management of Mild Traumatic Brain Injury Among Children
6 Sep, 2018 | 02:55h | UTCCommentaries: CDC releases updated guideline on diagnosis and management of pediatric mTBI – Kennedy Krieger Institute, via EurekAlert (free) AND CDC Seeks to Standardize Mild TBI Management in Kids – MedPage Today (free registration required) AND New advice on kids’ concussions calls for better tracking – Associated Press (free) AND CDC issues first guidelines to treat youth concussions – CNN (free)
Study: Prediction Rules to Detect Delirium at Hospital Admission
6 Sep, 2018 | 02:29h | UTCCommentary: New prediction rule may help detect delirium at hospital admission – ACP Hospitalist (free)
American Epilepsy Society: Five Things Physicians and Patients Should Question
2 Sep, 2018 | 02:31h | UTCAmerican Epilepsy Society: Five Things Physicians and Patients Should Question – Choosing Wisely (free)
Commentary: Choosing Wisely: 5 Practices to Question When Treating Epilepsy – NEJM Physician’s First Watch (free)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Study: The Impact of Exposure to Air Pollution on Cognitive Performance
2 Sep, 2018 | 02:33h | UTCThe impact of exposure to air pollution on cognitive performance – Proceedings of the National Academies of Sciences (link to abstract – $ for full-text)
Commentaries: Air pollution could be making us less intelligent – Science Magazine (free) AND Air Pollution Exposure Harms Cognitive Performance, Study Finds – NPR (free) AND Air pollution may harm cognitive intelligence, study says – BBC (free) AND Pollution May Dim Thinking Skills, Study in China Suggests – New York Times (10 articles per month are (free) AND Air pollution is making you less intelligent, according to a new study – World Economic Forum (free)
Systematic Review: Antidepressants for Treating Depression in Dementia
2 Sep, 2018 | 02:32h | UTCAntidepressants for treating depression in dementia – Cochrane Library (free for a limited period)
Summary: Antidepressants for treating depression in dementia – Cochrane Library (free)
“On the only measure of efficacy for which we had high-quality evidence (depression rating scale scores), antidepressants showed little or no effect.”
Guideline: Periprocedural Antithrombotic Management for Lumbar Puncture
2 Sep, 2018 | 02:04h | UTC
Study: Association of Cardiovascular Health Level in Older Age With Cognitive Decline and Incident Dementia
23 Aug, 2018 | 23:45h | UTCAssociation of Cardiovascular Health Level in Older Age With Cognitive Decline and Incident Dementia – JAMA (link to abstract – $ for full-text)
Commentaries: Study confirms that keeping the heart healthy also reduces dementia risk – NHS Choices (free) AND The Healthier Your Heart, the Healthier Your Brain May Be – The New York Times (10 articles per month are free) AND Cardiovascular Risk Factors Also Linked to Dementia – MedicalResearch.com (free)
Perspective: Exploring the Relationship Between Depression and Dementia
23 Aug, 2018 | 23:41h | UTCExploring the Relationship Between Depression and Dementia – JAMA (free for a limited period)
Study: Breastfeeding History and Risk of Stroke Among Parous Postmenopausal Women in the Women’s Health Initiative
23 Aug, 2018 | 23:38h | UTCCommentaries: Breastfeeding linked to lower stroke risk – Reuters (free) AND Breastfeeding may help protect mothers against stroke – AHA News (free)
“…ultimately, the study is observational, which means that it can only prove that breast feeding is associated with lower risk of stroke as opposed to being the cause of the lowered risk.” (from Reuters)