Neurology
Randomized Trial: Effect of Aerobic Exercise on Cognition in Younger Adults
7 Feb, 2019 | 00:45h | UTCEffect of aerobic exercise on cognition in younger adults: A randomized clinical trial – Neurology (link to abstract – $ for full-text)
Commentary: Exercise may improve thinking skills in people as young as 20 – American Academy of Neurology (free)
German Guidelines for the Treatment of Migraine Attacks and Prevention of Migraine
6 Feb, 2019 | 01:13h | UTCRelated Guidelines: Evidence-based guideline update: Pharmacologic treatment for episodic migraine prevention in adults: Report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society (free) AND Pharmacological management of migraine – Scottish Intercollegiate Guidelines Network (free)
Study: Long-term Effect of Thymectomy Plus Prednisone vs. Prednisone Alone in Non-thymomatous Myasthenia Gravis
4 Feb, 2019 | 22:29h | UTCLong-term effect of thymectomy plus prednisone versus prednisone alone in patients with non-thymomatous myasthenia gravis: 2-year extension of the MGTX randomised trial – The Lancet Neurology (link to abstract – $ for full-text)
Commentary: In myasthenia gravis, surgery to remove the thymus gland provides clinical benefits even five years later – University at Buffalo (free) AND Clinical benefits persist 5 years after thymectomy for myasthenia gravis – MDedge Neurology (free)
Related Commentary on Twitter
2y extension of the thymectomy in myasthenia gravis RCT: also at 5 years, thymectomy+prednisone > prednisone in patients with generalised non-thymomatous myasthenia gravishttps://t.co/nJZF4JRM5d@wolfegil @UBNewsSource @UBuffalo @TheLancetNeuro #neurology #neuromuscular pic.twitter.com/S62HWWlZ9Q
— Johan Lim (@DrJohanLim) February 2, 2019
Dysphagia: Interprofessional Management, Impact, and Patient‐Centered Care
4 Feb, 2019 | 21:32h | UTC
Examination of the Patient with Dizziness or Imbalance
3 Feb, 2019 | 16:51h | UTCExamination of the Patient with Dizziness or Imbalance – Medical Clinics of North America (free)
The Alzheimer’s Disease Clinical Spectrum: Diagnosis and Management
1 Feb, 2019 | 02:38h | UTC
Review: Role of Decompressive Craniectomy in Ischemic Stroke
29 Jan, 2019 | 21:59h | UTCRole of Decompressive Craniectomy in Ischemic Stroke – Frontiers in Neurology (free)
Central Nervous System Involvement in ANCA-Associated Vasculitis: What Neurologists Need to Know
29 Jan, 2019 | 21:55h | UTC
Study: Physical Activity, Common Brain Pathologies, and Cognition in Older Adults
28 Jan, 2019 | 23:47h | UTCPhysical activity, common brain pathologies, and cognition in community-dwelling older adults – Neurology (link to abstract – $ for full-text)
Commentaries: Daily Movement — Even Household Chores — May Boost Brain Health In Elderly – NPR (free) AND Keep Moving to Keep Brain Sharp in Old Age – U.S. News (free) AND Activity sharpens even dementia-affected brains, report suggests – The Guardian (free)
Viewpoint: The Rise of Pseudomedicine for Dementia and Brain Health
27 Jan, 2019 | 20:36h | UTCThe Rise of Pseudomedicine for Dementia and Brain Health – JAMA (free for a limited period)
Global, Regional, and National Burden of Multiple Sclerosis
27 Jan, 2019 | 18:41h | UTCInvited Commentary: A global perspective on the burden of multiple sclerosis (free)
Related Commentary on Twitter
The global, regional, and national burden of #multiplesclerosis between 1990 and 2016. #MS prevalence has increased substantially. Why? Due in part to improved #survival. Learn more in @TheLancetNeuro. https://t.co/4q3yfHNP8X #GBDstudy @IHME_UW pic.twitter.com/SBrGIaD80d
— Neurology Today (@NeurologyToday) January 24, 2019
Randomized Delayed-Start Trial of Levodopa in Parkinson’s Disease
24 Jan, 2019 | 00:21h | UTCRandomized Delayed-Start Trial of Levodopa in Parkinson’s Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Good News, Bad News on Levodopa for Parkinson’s Disease – U.S. News (free)
Study: Medication Review to Optimize and Potentially Reduce Psychotropic Drug Prescription in Institutionalized Dementia Patients
24 Jan, 2019 | 00:04h | UTCRelated: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)
New IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11)
22 Jan, 2019 | 00:29h | UTCCommentary: IASP Updates Classification of Chronic Pain – Clinical Advisor (free)
Related Commentary on Twitter
Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11) #PainJournal https://t.co/Riegvjag5N pic.twitter.com/9hquW4dDa1
— PAIN Journal (@PAINthejournal) January 16, 2019
“Opioids Don’t Work for Most People with Chronic Pain. So Why do We Still Prescribe Them?”
22 Jan, 2019 | 00:26h | UTCRelated study: Meta-Analysis: Opioids for Chronic Noncancer Pain (link to abstract and commentaries)
See also: Opioid Wisely – Choosing Wisely Canada (free) AND Guideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free)
Study: Blood Test May Detect Presymptomatic Alzheimer’s Disease
21 Jan, 2019 | 22:39h | UTCCommentaries: Blood test detects Alzheimer’s damage before symptoms – Washington University in St. Louis (free) AND Early prediction of Alzheimer’s progression: Blood protein – DZNE – German Center for Neurodegenerative Diseases (free) AND Blood test could detect Alzheimer’s more than 10 years earlier – study – The Guardian (free)
Related: Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons (link to abstract and commentaries) AND Identifying incipient dementia individuals using machine learning and amyloid imaging (free study and commentaries) AND High performance plasma amyloid-β biomarkers for Alzheimer’s disease (link to abstract and commentaries) AND Amyloid PET Scan for Predicting Alzheimer’s Disease in Mild Cognitive Impairment (free study and commentaries) AND Retinal Nerve Fiber Layer Thinning and Future Cognitive Decline (link to abstract and commentaries) AND Artificial Intelligence may Predict Alzheimer’s Years Before Diagnosis (link to abstract and commentaries)
Overview of Cochrane Reviews: Rehabilitation for People with Multiple Sclerosis
21 Jan, 2019 | 14:55h | UTCRehabilitation for people with multiple sclerosis: an overview of Cochrane Reviews – Cochrane Library (free)
Summary: Rehabilitation for persons with multiple sclerosis – Cochrane Library (free)
Systematic Review: Antidepressants do not Help Treat Depression in People Living with Dementia
20 Jan, 2019 | 13:47h | UTCAntidepressants do not help treat depression in people living with dementia – NIHR Signal (free)
Original Article: Antidepressants for treating depression in dementia – Cochrane Library (free)
Meta-Analysis: Worldwide Incidence of Aneurysmal Subarachnoid Hemorrhage
20 Jan, 2019 | 13:23h | UTCWorldwide Incidence of Aneurysmal Subarachnoid Hemorrhage According to Region, Time Period, Blood Pressure, and Smoking Prevalence in the Population: A Systematic Review and Meta-analysis – JAMA Neurology (free for a limited period)
Alcohol Use and Dementia: A Systematic Scoping Review
17 Jan, 2019 | 00:12h | UTCAlcohol use and dementia: a systematic scoping review – Alzheimer’s Research & Therapy (free)
Randomized Trial: Hematopoietic Stem Cell Transplantation for Patients with Multiple Sclerosis
16 Jan, 2019 | 00:51h | UTCEffect of Nonmyeloablative Hematopoietic Stem Cell Transplantation vs Continued Disease-Modifying Therapy on Disease Progression in Patients With Relapsing-Remitting Multiple Sclerosis: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
See also: Visual Abstract (free)
Commentaries: For some multiple sclerosis patients, knocking out the immune system might work better than drugs – Science (free) AND A remarkable new study shows stem cells can reverse MS in some patients – Vox (free) AND Expert reaction to study looking at blood stem cell transplantation as a MS treatment – Science Media Centre (free)
Guideline: Cerebral Palsy in Adults
16 Jan, 2019 | 00:37h | UTCCerebral palsy in adults – National Institute for Health and Care Excellence (free)
Study: Association of Body Mass Index and Waist-to-hip Ratio with Brain Structure
15 Jan, 2019 | 00:30h | UTCAssociation of body mass index and waist-to-hip ratio with brain structure: UK Biobank study – Neurology (link to abstract – $ for full-text)
Commentaries: Excessive body fat around the middle linked to smaller brain, study says – CNN (free) AND Excessive body fat around the middle linked to smaller brain size, study finds – American Academy of Neurology (free)
Guidelines for the Peri‐operative Care of People with Dementia
13 Jan, 2019 | 23:21h | UTCGuidelines for the peri‐operative care of people with dementia – Anaesthesia (free)
Review: Neurological Complications of Immune Checkpoint Inhibitors
13 Jan, 2019 | 19:49h | UTC