Neurology
Review: Updates in Refractory Status Epilepticus
24 May, 2018 | 22:22h | UTCUpdates in Refractory Status Epilepticus – Critical Care Research and Practice (free)
Source: Critical Care Reviews Newsletter
Retrospective Cohort: Atrial Fibrillation Burden and Risk of Stroke in Adults with Paroxysmal Atrial Fibrillation
23 May, 2018 | 12:48h | UTCCommentaries: Atrial Fibrillation Burden and Stroke Risk – American College of Cardiology (free) AND Greater burden of atrial fibrillation linked to higher stroke risk – Kaiser Permanente, via EurekAlert (free)
Guideline: Use of Atraumatic Needles in All Patients Undergoing Lumbar Puncture
23 May, 2018 | 12:32h | UTCRapid Recommendations: Atraumatic (pencil-point) versus conventional needles for lumbar puncture: a clinical practice guideline – The BMJ (free)
“We issue a strong recommendation for use of atraumatic needles in all patients (adults and children) undergoing lumbar puncture because they decrease complications and are no less likely to work than conventional needles”
Research: Clinical Features of Guillain-Barré Syndrome With vs Without Zika Virus Infection
23 May, 2018 | 12:23h | UTCClinical Features of Guillain-Barré Syndrome With vs Without Zika Virus Infection, Puerto Rico, 2016 – JAMA Neurology (link to abstract – $ for full-text)
Commentary: Study: GBS symptoms more severe when caused by Zika – CIDRAP (free)
Perspective: Ten Dubious Beliefs in Neurocritical Care
23 May, 2018 | 12:26h | UTCTen dubious beliefs in neurocritical care – PulmCrit (free)
Randomized Trial: Cannabidiol Reduces Seizures in Patients with Lennox–Gastaut Syndrome
23 May, 2018 | 12:22h | UTCEffect of Cannabidiol on Drop Seizures in the Lennox–Gastaut Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Cannabidiol significantly reduces seizures in patients with severe form of epilepsy – NYU School of Medicine (free) AND Cannabis Drug Reduces Drop Seizures in Severe Epilepsy – Medscape (free registration required) AND Cannabidiol Significantly Reduces Seizures in Patients with Lennox-Gastaut Syndrome – MD Magazine (free)
Cohort Study: Five-Year Risk of Stroke after TIA or Minor Ischemic Stroke
18 May, 2018 | 02:39h | UTCFive-Year Risk of Stroke after TIA or Minor Ischemic Stroke – New England Journal of Medicine (free)
Commentary: Elevated Stroke Risk Continues for 5 Years After TIA – NEJM Physician’s First Watch (free) AND Five Years after TIA or Minor Stroke, Second-Event Risk Persists – MedPage Today (free)
Randomized Controlled Trial: Tranexamic Acid for Hyperacute Primary Intracerebral Hemorrhage
18 May, 2018 | 02:36h | UTCEditorial: Haemostatic treatment for intracerebral haemorrhage (free)
Commentaries: Study: Drug to treat bleeding may reduce stroke deaths – UPI (free) AND Drug to treat bleeding may benefit some stroke patients, study finds – University of Nottingham, via EurekAlert (free)
Randomized Trial: MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset
18 May, 2018 | 02:37h | UTCMRI-Guided Thrombolysis for Stroke with Unknown Time of Onset – New England Journal of Medicine (free)
Editorial: MRI-Guided Intravenous Alteplase for Stroke — Still Stuck in Time (free)
Commentary: New treatment option for ‘wake-up’ stroke patients – University of Glasgow, via MedicalXpress (free)
Randomized Trial: Rivaroxaban Not Effective for Stroke Prevention after Embolic Stroke of Undetermined Source
18 May, 2018 | 02:38h | UTCCommentaries: NAVIGATE ESUS: Rivaroxaban Fails to Prevent More Recurrent Cryptogenic Strokes Than Aspirin – TCTMD (free) AND Rivaroxaban Not Superior to Aspirin for Patients with Embolic Stroke of Unknown Source – NEJM Physician’s First Watch (free)
Randomized Trial: Dual Antiplatelet Therapy in Acute Ischemic Stroke and High-Risk TIA
18 May, 2018 | 02:36h | UTCClopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA – New England Journal of Medicine (free)
Editorial: Antiplatelet Therapy after Ischemic Stroke or TIA (free)
Commentary: Dual Antiplatelet Therapy or Aspirin Alone After TIA or Minor Stroke? – NEJM Physician’s First Watch (free)
Clinical Guideline: Pharmacotherapy for Neuropathic Pain
18 May, 2018 | 02:33h | UTC
Cohort Study: Chemotherapy-Induced Neuropathy in Survivors of Childhood Cancer
18 May, 2018 | 02:32h | UTCChemotherapy-Induced Peripheral Neuropathy in Long-term Survivors of Childhood Cancer: Clinical, Neurophysiological, Functional, and Patient-Reported Outcomes – JAMA Neurology (free for a limited period)
Commentaries: Peripheral Neuropathy Common in Childhood Cancer Survivors – MPR (free) AND Chemo-Induced Neuropathy Common after Childhood Cancer – MedPage Today (free registration required)
Randomized Controlled Trial: Exercise Training Does Not Slow Dementia Progression
18 May, 2018 | 02:29h | UTCCommentaries: Exercise Doesn’t Slow Cognitive Decline in Patients with Dementia – NEJM Physician’s First Watch (free) AND Rigorous exercise does not halt dementia decline, study concludes – The Guardian (free) AND Expert reaction to effects of exercise on dementia in old people – Science Media Centre (free) AND Exercise ‘doesn’t slow’ progression of dementia – NHS Choices (free)
Review: Intensive Care for Patients with Aneurysmal Subarachnoid Hemorrhage
16 May, 2018 | 01:21h | UTCSource: Critical Care Reviews Newsletter
Research: Amyloid PET Scan for Predicting Alzheimer’s Disease in Mild Cognitive Impairment
16 May, 2018 | 01:19h | UTCCommentaries: Biomarkers, PET imaging may predict cognitive decline en route to Alzheimer’s – Health Imaging (free) AND Amyloid PET Scan Can Predict Progression to Alzheimer’s in Patients With Mild Cognitive Impairment – MedicalResearch.com (free)
Related Studies: Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons (link to abstract and free commentaries) AND Identifying incipient dementia individuals using machine learning and amyloid imaging (free full-text and commentaries) AND High performance plasma amyloid-β biomarkers for Alzheimer’s disease (link to abstract and free commentaries)
Study: Visual Screening Tool Improves Prediction of Developing Dementia
16 May, 2018 | 01:18h | UTCImproving Prediction of Dementia in Primary Care – Annals of Family Medicine (free)
Commentaries: Screening Tool Improves Dementia Prediction – Medscape (free registration required) AND Visual Test Could Help Predict Dementia Risk in Elders – NEJM Physician’s First Watch (free)
Meta-Analysis: Transcranial Magnetic Stimulation for Stroke Survivors
16 May, 2018 | 00:38h | UTCCommentaries: For Stroke Victims, Brain Magnetic Stimulation Leads to Improved Walking Speed – Wolters Kluwer, via NewsWise (free) AND Stroke survivors may benefit from magnetic brain stimulation – Medical News Today (free)
Retrospective Cohort: Achieved Systolic BP and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus
16 May, 2018 | 00:35h | UTCEffect of Achieved Systolic Blood Pressure on Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus: A Population-Based Retrospective Cohort Study – Diabetes Care (link to abstract – $ for full-text)
Commentaries: Diabetics with lower achieved SBP may be at greater risk for cardiovascular disease – Cardiovascular Business (free) AND No reduced CVD risk for SBP <120 mm hg in type 2 diabetes – MedicalXpress (free)
Case–Control Study: Smoking and Risk of Ischemic Stroke in Young Men
14 May, 2018 | 18:03h | UTCSmoking and Risk of Ischemic Stroke in Young Men – Stroke (link to abstract – $ for full-text)
Commentaries: Even young men who smoke have increased stroke risk – Reuters (free) AND Number of Cigarettes Smoked per Day Influences Stroke Risk in Young Men – TCTMD (free) AND Men younger than 50: the more you smoke, the more you stroke – AHA/ASA Newsroom (free)
FDA Safety Alert: Neurovascular Stents in the Treatment of Unruptured Brain Aneurysms
14 May, 2018 | 11:57h | UTCNeurovascular Stents Used for Stent-Assisted Coiling (SAC): Letter to Health Care Providers – Recommendations Associated With the Use of These Devices in the Treatment of Unruptured Brain Aneurysms – U.S. Food & Drug Administration (free)
Commentary: FDA Cautions on Stents for Unruptured Brain Aneurysms – NEJM Physician’s First Watch (free) AND FDA issues safety alert on stents used in aneurysm coiling – Univadis (free registration required)
Retrospective Cohort Studies: Risk of Stroke and TIA in Patients with Resolved Atrial Fibrillation
11 May, 2018 | 02:49h | UTCCommentaries: Tom Marshall: The importance of asking the right research question – BMJ Opinion (free) AND Patients who have had an irregular heart beat can’t ever be considered ‘cured’ – University of Birmingham (free)
Guideline Retraction: Parts of New AHA/ASA Acute Stroke Guidelines Rescinded
10 May, 2018 | 17:51h | UTCCorrection to: 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association – Stroke (free PDF)
Commentaries: AHA Rescinds Large Sections of New Stroke Guidelines – Medscape (free registration required) AND AHA/ASA retracts large portion of new stroke guidelines – Cardiovascular Business (free)
Cohort Study: Association of Mild Traumatic Brain Injury with Later Dementia
10 May, 2018 | 17:44h | UTCAssociation of Mild Traumatic Brain Injury With and Without Loss of Consciousness With Dementia in US Military Veterans – JAMA Neurology (free for a limited period)
Editorial: Risk of Dementia Outcomes Associated With Traumatic Brain Injury During Military Service (free)
Commentaries: Dementia Risk Doubles Following Concussion, UCSF Study Shows – University of California San Francisco (free) AND Vets with Head Injury More Likely To Develop Dementia – MedicalResearch.com (free)
See two recent cohort studies with similar results: Long-term risk of dementia among people with traumatic brain injury (link to abstract and free commentaries) AND Traumatic Brain Injury and the Risk of Dementia Diagnosis (free article and commentaries)
Randomized Controlled Trial: Folic Acid for Stroke Prevention in High-Risk Hypertensive Patients
10 May, 2018 | 17:40h | UTCPlatelet Count Affects Efficacy of Folic Acid in Preventing First Stroke – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Folic acid ‘may help reduce stroke risk in people with high blood pressure’ – NHS Choices (free) AND Folic Acid Supplements May Reduce Stroke Risk in Hypertensive Patients – American College of Cardiology (free) AND Folic Acid Cut Strokes in Hypertensive Patients on Enalapril – MedPage Today (free registration required) AND Folic acid supplementation may help prevent first stroke in high-risk patients with hypertension – ACP Internist (free)