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Neurology

Guideline: Vaccine-preventable Infections and Immunization in Multiple Sclerosis

3 Sep, 2019 | 01:07h | UTC

Practice guideline update summary: Vaccine-preventable infections and immunization in multiple sclerosis: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology (free PDF)

Commentaries: AAN Releases Multiple Sclerosis Vaccination Guidelines – Neurology Live (free) AND Regular vaccines safe, necessary for people with multiple sclerosis – UPI (free)

 


Cohort Study: Risk of Suicide Increased in Patients with Restless Legs Syndrome

27 Aug, 2019 | 01:44h | UTC

Association of Restless Legs Syndrome With Risk of Suicide and Self-harm – JAMA Network Open (free)

Commentaries: Suicide risk nearly three times as high for those with restless legs syndrome – UPI (free) AND Restless Legs Syndrome Linked to Increased Risk for Self-Harm or Suicide – NEJM Journal Watch (free)

 


Debate Sparks Over LATE, a Recently Recognized Dementia

27 Aug, 2019 | 00:30h | UTC

Debate Sparks Over LATE, a Recently Recognized Dementia – JAMA (free for a limited period)

Related: Consensus Report: Limbic-predominant Age-related TDP-43 Encephalopathy (LATE) (free report and commentaries)

 


Study: High Blood Pressure in Adulthood Linked to Late-life Brain Structure Changes

25 Aug, 2019 | 21:32h | UTC

Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study – The Lancet Neurology (free)

Commentaries: Blood pressure control as an intervention to prevent dementia – The Lancet Neurology (free) AND Early blood pressure changes linked to poorer brain health – University College London (free) AND High blood pressure in mid-30s may pose risk to brain health – BBC (free) AND Blood pressure in our 30s and 40s has lasting impact on brain health – Medical News Today (free)

Related Study: Midlife to Late-Life Blood Pressure Patterns and Incident Dementia (link to abstract and commentaries)

 

Related Commentary on Twitter

 


Update on Best Practice of Deep Brain Stimulation in Parkinson’s Disease

25 Aug, 2019 | 13:36h | UTC

An update on best practice of deep brain stimulation in Parkinson’s disease – Therapeutic Advances in Neurological Disorders (free)

Related Reviews: Deep Brain Stimulation to Alleviate Freezing of Gait and Cognitive Dysfunction in Parkinson’s Disease: Update on Current Research and Future Perspectives – Frontiers in Neuroscience (free) AND DBS Programming: An Evolving Approach for Patients with Parkinson’s Disease – Parkinson’s Disease (free) AND The role of deep brain stimulation in Parkinson’s disease: an overview and update on new developments – Neuropsychiatric Disease and Treatment (free)

 


Study: Dual Antiplatelet Therapy Should be Used for 21 Days After Minor Ischemic Stroke or High-risk Transient Ischemic Attack

20 Aug, 2019 | 08:32h | UTC

Outcomes Associated With Clopidogrel-Aspirin Use in Minor Stroke or Transient Ischemic Attack: A Pooled Analysis of Clopidogrel in High-Risk Patients With Acute Non-Disabling Cerebrovascular Events (CHANCE) and Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trials – JAMA Neurology (free for a limited period)

Related Study: The Benefits of Clopidogrel-aspirin Combination after Minor Stroke/TIA occurs Predominantly Within the First 21 Days (free)

Related Guideline: Dual Antiplatelet Therapy for Acute High-Risk TIA and Minor Ischemic Stroke – The BMJ (free)

 


[Abstract Only] Cohort Study: ‘Silent’ Strokes Common After Non-cardiac Surgery, Linked to Cognitive Decline

18 Aug, 2019 | 22:07h | UTC

Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study – The Lancet (link to abstract – $ for full-text)

Commentaries: ‘Silent’ strokes common after surgery, linked to cognitive decline – McMaster University (free) AND ‘Silent’ strokes after elective surgeries in older adults double their risk of later cognitive decline, study finds – The Globe and Mail (free)

 

Related Commentary on Twitter

 


Cohort Study: Association of Social Contact with Dementia and Cognition

18 Aug, 2019 | 21:57h | UTC

Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study – PLOS Medicine (free)

Commentaries: Socially active 60-year-olds face lower dementia risk – University College London (free) AND Social Contact Associated With Lower Dementia Risk – MD Magazine (free)

 


Essential Tremor: Diagnosis and Management

16 Aug, 2019 | 07:55h | UTC

Essential tremor: diagnosis and management – The BMJ (free for a limited period)

 


AAN Guidelines for the Pharmacologic Prevention and Treatment of Migraine in Children and Adolescents

15 Aug, 2019 | 10:27h | UTC

Practice guideline update summary: Pharmacologic treatment for pediatric migraine prevention – Neurology (fee PDF)

See also: Practice guideline update summary: Acute treatment of migraine in children and adolescents – Neurology (free PDF)

Commentaries: AAN issues guidelines for treatment of migraine in children and teens – American Academy of Neurology (free) AND Guidelines Updated on Preventing and Treating Migraine in Children and Teens – NEJM Journal Watch (free)

 


Study: Midlife to Late-Life Blood Pressure Patterns and Incident Dementia

14 Aug, 2019 | 10:33h | UTC

Association of Midlife to Late-Life Blood Pressure Patterns With Incident Dementia – JAMA (free for a limited period)

Related Research: Association of Intensive vs Standard Blood Pressure Control With Cerebral White Matter Lesions – JAMA (free for a limited period)

Editorial: Blood Pressure, Brain Volume and White Matter Hyperintensities, and Dementia Risk (free for a limited period)

Video Summary: Hypertension and Dementia (free)

Commentary: Expert reaction to two studies looking at blood pressure and dementia – Science Media Centre (free)

 


The Entire Human Brain in ‘Unprecedented’ Detail, Thanks to Powerful MRI

14 Aug, 2019 | 08:26h | UTC

The entire human brain in ‘unprecedented’ detail, thanks to powerful MRI – STAT (free)

 


Cohort Study: Association of Hearing Loss with Dementia

13 Aug, 2019 | 05:24h | UTC

Association of Hearing Loss With Dementia – JAMA Network Open (free)

Commentary: Middle-age hearing loss linked to dementia – Reuters (free)

Related Meta-Analysis: Association of Age-Related Hearing Loss With Cognitive Function (free study and commentaries)

 


Debate: Nonconvulsive Seizures and Nonconvulsive Status Epilepticus in the Neuro ICU Should or Should Not be Treated Aggressively?

13 Aug, 2019 | 01:29h | UTC

Nonconvulsive seizures and nonconvulsive status epilepticus in the Neuro ICU should or should not be treated aggressively: a debate – Clinical Neurophysiology Practice (free)

 


Diagnosis and Management of Autonomic Dysfunction in Dementia Syndromes

13 Aug, 2019 | 00:58h | UTC

Diagnosis and Management of Autonomic Dysfunction in Dementia Syndromes – Current Treatment Options in Neurology (free)

 


Cohort Study and Meta-Analysis: Long-term Antithrombotic Therapy and Risk of Intracranial Hemorrhage from Cerebral Cavernous Malformations

11 Aug, 2019 | 21:39h | UTC

Long-term antithrombotic therapy and risk of intracranial haemorrhage from cerebral cavernous malformations: a population-based cohort study, systematic review, and meta-analysis – The Lancet Neurology (free)

Invited Commentary: Antithrombotics and bleeding risk: paradoxical findings (free)

 

Related Commentary on Twitter

https://twitter.com/BleedingStroke/status/1159372784377782272

 


Complex Regional Pain Syndrome: A Narrative Review for the Practicing Clinician

9 Aug, 2019 | 07:24h | UTC

Complex regional pain syndrome: a narrative review for the practising clinician – British Journal of Anaesthesia (free)

Related Guidelines: Standards for the diagnosis and management of complex regional pain syndrome: Results of a European Pain Federation task force – European Journal of Pain (free) AND Complex regional pain syndrome in adults (2nd edition) – UK guidelines for diagnosis, referral and management in primary and secondary care 2018 – Royal College of Physicians (free PDF)

 


Cohort Study: Major Surgery Linked to Small, Long Term Decline in Brain Functioning

9 Aug, 2019 | 06:45h | UTC

Association between major surgical admissions and the cognitive trajectory: 19 year follow-up of Whitehall II cohort study – The BMJ (free)

Commentaries: Major surgery associated with small, long term decline in brain functioning – The BMJ (free) AND Major surgeries linked to small decline in mental functioning in older age – Reuters (free)

 


Cohort Study: Ideal Cardiovascular Health at Age 50 Linked to Lower Dementia Later in Life

9 Aug, 2019 | 06:34h | UTC

Association of ideal cardiovascular health at age 50 with incidence of dementia: 25 year follow-up of Whitehall II cohort study – The BMJ (free)

Editorial: The determinants of cognitive decline and dementia (free)

Commentaries: Good heart health at age 50 linked to lower dementia risk later in life – The BMJ (free) AND The implications of cardiovascular health for dementia – The BMJ Opinion (free)

 


Podcast: Stroke and TIA Deconstructed

6 Aug, 2019 | 08:04h | UTC

#164 Stroke and TIA Deconstructed – The Curbsiders Internal Medicine Podcast (free audio)

 


[Abstract Only] Study: Blood Test Can Identify Pre-Clinical Brain Changes Linked to Alzheimer’s Disease

5 Aug, 2019 | 02:14h | UTC

High-precision plasma β-amyloid 42/40 predicts current and future brain amyloidosis – Neurology (link to abstract – $ for full-text)

Commentaries: Blood test may accurately identify people with early Alzheimer’s brain changes – Washington University School of Medicine in St. Louis (free) AND The new blood test for Alzheimer’s disease: developed in a study without patients – Medium (free)

 


Perspective: A Brain Scan May Predict Alzheimer’s. Should You Get One?

5 Aug, 2019 | 02:13h | UTC

A Brain Scan May Predict Alzheimer’s. Should You Get One? – The New York Times (10 articles per month are free)

 


Randomized Trial and Meta-analysis: Standard vs. Intensive Blood Pressure Control on the Risk of Recurrent Stroke

2 Aug, 2019 | 02:50h | UTC

Effect of Standard vs Intensive Blood Pressure Control on the Risk of Recurrent Stroke: A Randomized Clinical Trial and Meta-analysis – JAMA Neurology (free for a limited period)

Editorial: Challenges to Realizing Benefits From More Intensive Blood Pressure Control for Preventing Recurrent Stroke – JAMA Neurology (free for a limited period)

 


Guidelines for the Treatment of Huntington’s Disease

2 Aug, 2019 | 00:51h | UTC

International Guidelines for the Treatment of Huntington’s Disease – Frontiers in Neurology (free)

Related Guideline: Evidence-based guideline: Pharmacologic treatment of chorea in Huntington disease: Report of the Guideline Development Subcommittee of the American Academy of Neurology (free)

 


Assessing and Counseling the Older Driver: A Concise Review for the Generalist Clinician

2 Aug, 2019 | 00:53h | UTC

Assessing and Counseling the Older Driver: A Concise Review for the Generalist Clinician – Mayo Clinic Proceedings (free)

 


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