Neurology
Review: Treating Restless Legs Syndrome in the Context of Sleep Disordered Breathing Comorbidity
23 Oct, 2019 | 07:19h | UTC
[Abstract Only] Study: Neurodegenerative Disease Mortality Increased Among Former Professional Soccer Players
22 Oct, 2019 | 08:09h | UTCNeurodegenerative Disease Mortality among Former Professional Soccer Players – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Dementia in football: Ex-players three and a half times more likely to die of condition – BBC (free) AND Study shows more thinking problems in former pro soccer players – Reuters (free)
Related Commentary on Twitter
Just published: In a study in which death certificates were used to compare the causes of death among 7676 former Scottish #soccer players and 23,028 matched controls, mortality from neurodegenerative disease was higher among former players. https://t.co/MFEQPGGFRP
— NEJM (@NEJM) October 21, 2019
[Abstract Only] Study: Pan-viral Serology Implicates Enteroviruses in Acute Flaccid Myelitis
22 Oct, 2019 | 08:08h | UTCPan-viral serology implicates enteroviruses in acute flaccid myelitis – Nature (link to abstract – $ for full-text)
Commentaries: ‘Missing’ Virus Detected in Dozens of Children Paralyzed by Polio-Like Illness – UC San Francisco (free) AND What Causes a Mysterious Paralysis in Children? Researchers Find Viral Clues – The New York Times (10 articles per month are free) AND Virus could be the cause of mysterious polio-like illness AFM, study says – CNN (free)
Randomized Trial: Including the Family in Perioperative Care of Older Adults Can Reduce Postoperative Delirium
22 Oct, 2019 | 07:59h | UTCEffect of the Tailored, Family-Involved Hospital Elder Life Program on Postoperative Delirium and – Function in Older Adults: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
Commentaries: Including the Family in Perioperative Care of Older Adults—A Call for HELP – JAMA Internal Medicine (free for a limited period) AND Family members can help reduce the incidence of post-operative delirium by up to 16.8% – News Medical (free)
Cognitive Deficits Following Intensive Care
22 Oct, 2019 | 07:28h | UTCCognitive Deficits Following Intensive Care – Deutsches Ärzteblatt international (free)
Source: Critical Care Reviews Newsletter
The Hyperactivity–Impulsivity–Irritability–Disinhibition–Aggression–Agitation Domain in Alzheimer’s Disease: Current Management and Future Directions
20 Oct, 2019 | 22:22h | UTC
Review: Management of Blood Pressure in Stroke
18 Oct, 2019 | 08:21h | UTCManagement of blood pressure in stroke – International Journal of Cardiology Hypertension (free)
Related Guidelines: 2018 AHA/ASA Guidelines for the Early Management of Patients With Acute Ischemic Stroke (free) AND AHA/ASA Guidelines for the Management of Spontaneous Intracerebral Hemorrhage (free) AND Canadian Stroke Best Practice Recommendations for Acute Stroke Management (free) AND Stroke and transient ischaemic attack in over 16s: diagnosis and initial management – National Institute for Health and Care Excellence (free)
[Abstract Only] Study: Moderation of Neural Excitation Promotes Longevity
17 Oct, 2019 | 08:24h | UTCModeration of neural excitation promotes longevity – Nature News (free)
Original Article: Regulation of lifespan by neural excitation and REST – Nature (link to abstract – $ for full-text)
See also: Here’s a brain teaser: Surprising study shows reduced neuronal activity extends life – STAT (free) AND In a first, scientists pinpoint neural activity’s role in human longevity – Harvard Medical School (free)
Study: Association of Neurocognitive and Physical Function With Gait Speed in Midlife
16 Oct, 2019 | 10:26h | UTCAssociation of Neurocognitive and Physical Function With Gait Speed in Midlife – JAMA Network Open (free)
Commentaries: Gait Speed Reveals Clues to Lifelong Health – JAMA Network Open (free) AND Slow Gait Speed at Midlife May Be Predictor of Accelerated Aging – NEJM Journal Watch (free) AND Slow walking speed in midlife linked with faster aging – Medical News Today (free)
Review: Central Pontine Myelinosis and Osmotic Demyelination Syndrome
16 Oct, 2019 | 10:25h | UTCCentral Pontine Myelinosis and Osmotic Demyelination Syndrome – Deutsches Ärzteblatt international (free)
Source: Critical Care Reviews Newsletter
[Abstract Only] Randomized Trial: Effect of Collaborative Dementia Care via Telephone and Internet on Quality of Life, Caregiver Well-being, and Health Care Use
16 Oct, 2019 | 10:22h | UTCEffect of Collaborative Dementia Care via Telephone and Internet on Quality of Life, Caregiver Well-being, and Health Care UseThe Care Ecosystem Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Monthly phone check-in may mean less depression for families of patients with dementia – University of California – San Francisco (free) AND Phone support tied to better outcomes for dementia patients, caregivers – Reuters (free) AND Dementia Outcomes Improved With Supportive Care – MedPage Today (free registration required)
Audio Interview: Effect of Collaborative Dementia Care on Quality of Life, Caregiver Well-being, and Health Care Use (free)
[Abstract Only] Meta-Analysis: Comparative Efficacy of Interventions for Aggressive and Agitated Behaviors in Dementia
15 Oct, 2019 | 10:35h | UTCComparative Efficacy of Interventions for Aggressive and Agitated Behaviors in Dementia: A Systematic Review and Network Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Non-pharmacologic treatments may be more effective for psychiatric symptoms of dementia – St. Michael’s Hospital (free) AND To ease dementia agitation, drugs may not be best option – Reuters (free)
[Abstract Only] Randomized Trial: Treatments for Multiple Sclerosis Compared
15 Oct, 2019 | 08:35h | UTCSafety and efficacy of ozanimod versus interferon beta-1a in relapsing multiple sclerosis (RADIANCE): a multicentre, randomised, 24-month, phase 3 trial – The Lancet Neurology (link to abstract – $ for full-text)
Commentary: Measure From RADIANCE Data Suggests Ozanimod More Effective in Slowing MS Disease Activity – AJMC (free)
Source: EvidenceAlerts
[Abstract Only] Randomized Trial: Anti-CD19 Monoclonal Antibody Tested for the Treatment of Neuromyelitis Optica Spectrum Disorder
15 Oct, 2019 | 08:29h | UTCInebilizumab for the treatment of neuromyelitis optica spectrum disorder (N-MOmentum): a double-blind, randomised placebo-controlled phase 2/3 trial – The Lancet (link to abstract – $ for full-text)
Commentary: Anti-CD19 MAb Trial Halted Early for Benefit in NMO – Medscape (free registration required)
Meta-Analysis: Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management
14 Oct, 2019 | 08:30h | UTCSource: EvidenceAlerts
Systematic Review: Interventions for Preventing Falls in People After Stroke
14 Oct, 2019 | 08:09h | UTCInterventions for preventing falls in people after stroke – Cochrane Library (free)
HHS Guide for Clinicians on the Appropriate Dosage Reduction or Discontinuation of Long-Term Opioid Analgesics
11 Oct, 2019 | 09:44h | UTCNews Release: HHS Announces Guide for Appropriate Tapering or Discontinuation of Long-Term Opioid Use – U.S. Department of Health and Human Services (free) AND
Commentaries: Patient-Centered Reduction or Discontinuation of Long-term Opioid Analgesics: The HHS Guide for Clinicians – JAMA (free for a limited period) AND With a new guide to tapering opioids, federal health officials seek a balanced approach to prescribing – STAT (free) AND Don’t Force Patients Off Opioids Abruptly, New Guidelines Say, Warning Of Severe Risks – NPR (free)
Author Interview: The HHS Guide to Patient-Centered Dose Reduction or Discontinuation of Long-term Opioids – JAMA (free)
Related: Pain Management With Opioids in 2019-2020 – JAMA (free registration required)
Position Statement: Recommendations on the Use of Ultrasound Guidance for Adult Lumbar Puncture
11 Oct, 2019 | 09:35h | UTCEditorial: Ultrasound Guidance for Lumbar Puncture: A Consideration, Not an Obligation (free)
Review: Pure Autonomic Failure
10 Oct, 2019 | 09:09h | UTCPure Autonomic Failure – Mayo Clinic Proceedings (free)
Expert Statement on the ICU Management of Thrombotic Thrombocytopenic Purpura
8 Oct, 2019 | 10:09h | UTCRelated Guidelines: Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies – British Journal of Haematology (free) AND Diagnostic and treatment guidelines for thrombotic thrombocytopenic purpura (TTP) 2017 in Japan – International Journal of Hematology (free) AND Consensus opinion on diagnosis and management of thrombotic microangiopathy in Australia and New Zealand – Nephrology (free)
ESC Consensus Report: Cardiovascular Care of Patients with Stroke and High Risk of Stroke
8 Oct, 2019 | 10:05h | UTC
Study: Consuming More than 14.0 Drinks per Week Associated with Lower Cognitive Scores Among Older Individuals
7 Oct, 2019 | 00:54h | UTCCommentaries: Alcohol and dementia risk: A complex relationship – Medical News Today (free) AND Alcohol Consumption May Increase Dementia Risk in Older Adults – Psychiatric News Alert (free) AND Expert reaction to study looking at alcohol and risk of dementia and cognitive decline – Science Media Centre (free)
[Abstract Only] Study: Similar Outcomes with Medical Management or Mechanical Thrombectomy in Mild Strokes
7 Oct, 2019 | 00:56h | UTCMedical Management vs Mechanical Thrombectomy for Mild Strokes: An International Multicenter Study and Systematic Review and Meta-analysis – JAMA Neurology (link to abstract – $ for full-text)
Commentaries: Medical Therapy Vs Endovascular Therapy: Similar Outcomes for Mild Strokes – Neurology Today (free) AND Similar Benefits for Thrombectomy, Medical Management, in Mild Stroke – Medscape (free)
Related Commentary on Twitter
Mechanical #thrombectomy shows similar efficacy & safety profile compared w/ best medical management for patients with #stroke with mild-deficits emergency large-vessel occlusion. Study details in @JAMANeuro. https://t.co/UIP728yfI6
— Neurology Today (@NeurologyToday) September 25, 2019
A Comprehensive Algorithm for Management of Neuropathic Pain
4 Oct, 2019 | 08:06h | UTCA Comprehensive Algorithm for Management of Neuropathic Pain – Pain Medicine (free)
Related Guidelines: Neuropathic pain in adults: pharmacological management in non-specialist settings – National Institute for Health and Care Excellence (free) AND Pharmacologic management of chronic neuropathic pain: Review of the Canadian Pain Society consensus statement – Canadian Family Physician (free) AND Executive summary of the Clinical Guidelines of Pharmacotherapy for Neuropathic Pain: second edition by the Japanese Society of Pain Clinicians – Journal of Anesthesia (free)
[Abstract Only] Randomized Trial: Therapeutic Hypothermia Beneficial for Patients with Cardiac Arrest and Nonshockable Rhythm
3 Oct, 2019 | 08:16h | UTCTargeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Cooling cardiac arrest patients may protect brain function – UPI (free) AND Hypothermia Helps After Cardiac Arrest With Nonshockable Rhythm – MedPage Today (free registration required)