Neurology
Current Concepts in Imaging and Endovascular Treatment of Acute Ischemic Stroke: Implications for the Clinician
24 Sep, 2019 | 07:39h | UTC
Cochrane Special Collection: Diagnosing Dementia
20 Sep, 2019 | 08:06h | UTCCochrane Special Collection: Diagnosing Dementia – Cochrane Library (free articles)
Commentary: Dementia diagnosis: a decade of evidence – Evidently Cochrane (free)
AAN Recommends People 65+ be Screened Yearly for Memory Problems
20 Sep, 2019 | 08:03h | UTCNews Release: AAN Recommends People 65+ be Screened Yearly for Memory Problems – American Academy of Neurology (free)
Original Recommendations: Quality improvement in neurology: Mild cognitive impairment quality measurement set – American Academy of Neurology (free PDF)
USPSTF Disagrees: USPSTF Draft Statement: Insufficient Evidence to Recommend Screening for Cognitive Impairment in Older Adults (free)
Viewpoint: “It’s All in Your Head”—Medicine’s Silent Epidemic
17 Sep, 2019 | 08:01h | UTC“It’s All in Your Head”—Medicine’s Silent Epidemic – JAMA Neurology (free for a limited period)
Cohort Study: Donepezil Associated with Increased Risk of Rhabdomyolysis
17 Sep, 2019 | 08:07h | UTCCommentaries: Commonly used drug for Alzheimer’s disease doubles risk of hospitalization – Canadian Medical Association Journal (free) Study: Common Alzheimer’s disease drug doubles hospitalization risk – UPI (free) AND Rhabdomyolysis risk with donepezil double that of other AD meds – OnMedica (free)
Cohort Study: Associations of Subjective Memory Complaints and Simple Memory Task Scores with Future Dementia in the Primary Care Setting
17 Sep, 2019 | 01:05h | UTCCommentary: Memory complaints, simple scores predict dementia in primary care – Univadis (free registration required)
Meta-Analysis: Epilepsy Duration and Seizure Outcome in Epilepsy Surgery
17 Sep, 2019 | 01:07h | UTCCommentary: Epilepsy surgery: The earlier the better, overview study shows – University of Gothenburg (free)
Depression and Suicidality in Multiple Sclerosis: Red Flags, Management Strategies, and Ethical Considerations
17 Sep, 2019 | 01:00h | UTC
Randomized Trial: Antibiotic Impregnated Ventriculoperitoneal Shunts Reduce Infection Risk
16 Sep, 2019 | 02:21h | UTCCommentaries: Comparing antibiotic, silver, and standard ventriculoperitoneal shunts – The Lancet (free)
AND Antibiotic-impregnated shunt could prevent hydrocephalus infections, save millions – News Medical (free) AND Innovative treatment to prevent common brain infection could save NHS 7 million pounds per year – University of Liverpool (free)
USPSTF Draft Statement: Insufficient Evidence to Recommend Screening for Cognitive Impairment in Older Adults
11 Sep, 2019 | 08:34h | UTCCommentary: USPSTF: Evidence Lacking for Cognitive Screening in Older Adults – Physician’s Briefing (free)
Scientific Advances in and Clinical Approaches to Small-Fiber Polyneuropathy
11 Sep, 2019 | 08:16h | UTCScientific Advances in and Clinical Approaches to Small-Fiber Polyneuropathy: A Review – JAMA Neurology (free for a limited period)
Related: Diagnosis and management of sensory polyneuropathy – The BMJ (free) AND Small‐fiber neuropathy: Expanding the clinical pain universe – Journal of the Peripheral Nervous System (free) AND Small-fiber neuropathy definition, diagnosis, and treatment – Neurological Sciences (free)
Systematic Review: Antiviral Treatment for Bell’s Palsy
11 Sep, 2019 | 00:06h | UTCAntiviral treatment for Bell’s palsy (idiopathic facial paralysis) – Cochrane Library (free)
Summary: Antiviral treatment for Bell’s palsy – Cochrane Library (free)
“The combination of antivirals and corticosteroids may have little or no effect on rates of incomplete recovery in comparison to corticosteroids alone”
Canadian Guideline for Parkinson Disease
10 Sep, 2019 | 01:52h | UTCCanadian guideline for Parkinson disease – Canadian Medical Association Journal (free)
Related: Parkinson’s disease in adults – National Institute for Health and Care Excellence (NICE) Guideline (free) AND Choosing Wisely: five recommendations related to tests, treatments, and procedures at risk of inappropriateness in the cure of Parkinson’s disease (LIMPE-DISMOV Academy) – Neurological Sciences (free)
A Systematic Review of Clinical Guidelines on the Management of Acute, Community-acquired CNS Infections
9 Sep, 2019 | 00:07h | UTCRelated: The UK joint specialist societies guideline on the diagnosis and management of acute meningitis and meningococcal sepsis in immunocompetent adults (free) AND ESCMID guideline: diagnosis and treatment of acute bacterial meningitis (free) AND Meningitis (bacterial) and meningococcal septicaemia in under 16s: recognition, diagnosis and management – National Institute for Health and Care Excellence (free) AND Management of suspected viral encephalitis in adults – Association of British Neurologists and British Infection Association National Guidelines (free) AND Management of suspected viral encephalitis in children – Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group National Guidelines (free)
[Abstract Only] Observational Study Suggests Hearing Aids May Have a Role in Preventing Dementia and Depression in Older Adults
8 Sep, 2019 | 23:04h | UTCCan Hearing Aids Delay Time to Diagnosis of Dementia, Depression, or Falls in Older Adults? – Journal of the American Geriatrics Society (link to abstract – $ for full-text)
Commentaries: Hearing aids linked to lower risk of dementia, depression and falls – University of Michigan (free) AND Hearing Aids May Reduce Risk of Depression, Anxiety, Dementia in Older Adults – Psychiatric News Alert (free)
Systematic Review: Pharmacological Interventions for the Treatment of Delirium in Critically Ill Adults
5 Sep, 2019 | 08:16h | UTCPharmacological interventions for the treatment of delirium in critically ill adults – Cochrane Library (free)
Summary: Medicines to treat delirium in critically ill adult patients – Cochrane Library (free)
Related Systematic Reviews: Antipsychotics for Treating Delirium in Hospitalized Adults: A Systematic Review – Annals of Internal Medicine (free) AND Antipsychotics for Preventing Delirium in Hospitalized Adults: A Systematic Review – Annals of Internal Medicine (free)
Systematic Review: Antipsychotics for Treating Delirium in Hospitalized Adults
3 Sep, 2019 | 01:29h | UTC
Systematic Review: Antipsychotics for Preventing Delirium in Hospitalized Adults
3 Sep, 2019 | 01:27h | UTC
Guideline: Vaccine-preventable Infections and Immunization in Multiple Sclerosis
3 Sep, 2019 | 01:07h | UTCCommentaries: AAN Releases Multiple Sclerosis Vaccination Guidelines – Neurology Live (free) AND Regular vaccines safe, necessary for people with multiple sclerosis – UPI (free)
Cohort Study: Risk of Suicide Increased in Patients with Restless Legs Syndrome
27 Aug, 2019 | 01:44h | UTCAssociation of Restless Legs Syndrome With Risk of Suicide and Self-harm – JAMA Network Open (free)
Commentaries: Suicide risk nearly three times as high for those with restless legs syndrome – UPI (free) AND Restless Legs Syndrome Linked to Increased Risk for Self-Harm or Suicide – NEJM Journal Watch (free)
Debate Sparks Over LATE, a Recently Recognized Dementia
27 Aug, 2019 | 00:30h | UTCDebate Sparks Over LATE, a Recently Recognized Dementia – JAMA (free for a limited period)
Related: Consensus Report: Limbic-predominant Age-related TDP-43 Encephalopathy (LATE) (free report and commentaries)
Study: High Blood Pressure in Adulthood Linked to Late-life Brain Structure Changes
25 Aug, 2019 | 21:32h | UTCCommentaries: Blood pressure control as an intervention to prevent dementia – The Lancet Neurology (free) AND Early blood pressure changes linked to poorer brain health – University College London (free) AND High blood pressure in mid-30s may pose risk to brain health – BBC (free) AND Blood pressure in our 30s and 40s has lasting impact on brain health – Medical News Today (free)
Related Study: Midlife to Late-Life Blood Pressure Patterns and Incident Dementia (link to abstract and commentaries)
Related Commentary on Twitter
Rising blood pressure in people as young as 36 is linked to markers of poorer brain health in later life, including blood vessel damage and brain shrinkage, finds a new study led by Prof Jonathan Schott @jmschott @UCLIoN @drcionucl @UKDRI @TheLancetNeuro https://t.co/fTZR8cdLlv
— UCL News (@uclnews) August 21, 2019
Update on Best Practice of Deep Brain Stimulation in Parkinson’s Disease
25 Aug, 2019 | 13:36h | UTCRelated Reviews: Deep Brain Stimulation to Alleviate Freezing of Gait and Cognitive Dysfunction in Parkinson’s Disease: Update on Current Research and Future Perspectives – Frontiers in Neuroscience (free) AND DBS Programming: An Evolving Approach for Patients with Parkinson’s Disease – Parkinson’s Disease (free) AND The role of deep brain stimulation in Parkinson’s disease: an overview and update on new developments – Neuropsychiatric Disease and Treatment (free)
Study: Dual Antiplatelet Therapy Should be Used for 21 Days After Minor Ischemic Stroke or High-risk Transient Ischemic Attack
20 Aug, 2019 | 08:32h | UTCRelated Study: The Benefits of Clopidogrel-aspirin Combination after Minor Stroke/TIA occurs Predominantly Within the First 21 Days (free)
Related Guideline: Dual Antiplatelet Therapy for Acute High-Risk TIA and Minor Ischemic Stroke – The BMJ (free)
[Abstract Only] Cohort Study: ‘Silent’ Strokes Common After Non-cardiac Surgery, Linked to Cognitive Decline
18 Aug, 2019 | 22:07h | UTCPerioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study – The Lancet (link to abstract – $ for full-text)
Commentaries: ‘Silent’ strokes common after surgery, linked to cognitive decline – McMaster University (free) AND ‘Silent’ strokes after elective surgeries in older adults double their risk of later cognitive decline, study finds – The Globe and Mail (free)
Related Commentary on Twitter
NEW: Perioperative covert stroke is associated with increased risk of cognitive decline 1 year after non-cardiac surgery & occurred in 1 in 14 patients aged ≥65 years undergoing non-cardiac surgery: findings from NeuroVISION, a prospective cohort study https://t.co/jWXkl6GllU pic.twitter.com/w3mDziUPSR
— The Lancet (@TheLancet) August 16, 2019