Neurology
Systematic review: Autoimmune encephalitis related to cancer treatment with immune checkpoint inhibitors – nivolumab was responsible for 61% of cases; onset occurred after a median of 3.5 treatment cycles, but very early and late presentations were common
20 May, 2021 | 08:13h | UTCAutoimmune Encephalitis Related to Cancer Treatment With Immune Checkpoint Inhibitors: Systematic Review – Neurology (link to abstract – $ for full-text)
NICE Guideline Update | Headaches in over 12s: diagnosis and management.
18 May, 2021 | 07:14h | UTCHeadaches in over 12s: diagnosis and management – National Institute for Health and Care Excellence
2 recent meta-analysis highlight the benefits of short term (30 days) dual antiplatelet therapy with aspirin + clopidogrel in patients within 24 hours of high-risk transient ischemic attack or mild-moderate ischemic stroke.
17 May, 2021 | 08:16h | UTCMeta-analysis 1: Dual Antiplatelet Therapy Versus Aspirin in Patients With Stroke or Transient Ischemic Attack: Meta-Analysis of Randomized Controlled Trials – Stroke
Meta-analysis 2: Efficacy and Safety of Using Dual Versus Monotherapy Antiplatelet Agents in Secondary Stroke Prevention: Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials – Circulation (link to abstract – $ for full-text)
Commentary: Dual vs. Monotherapy Antiplatelet Agents in Secondary Stroke Prevention – American College of Cardiology
Related Guideline: Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke – The BMJ
Unnecessary care? 1 in 3 patients with advanced dementia and atrial fibrillation still given anticoagulants.
17 May, 2021 | 08:13h | UTCOriginal study: Anticoagulant Use for Atrial Fibrillation Among Persons With Advanced Dementia at the End of Life – JAMA Internal Medicine (free for a limited period)
Editorial: Anticoagulation at the End of Life: Time for a Rational Framework (free for a limited period)
Polypharmacy, inappropriate prescribing, and deprescribing in older people: through a sex and gender lens.
14 May, 2021 | 08:30h | UTCPodcast with the author: Dr Paula Rochon talks with The Lancet Healthy Longevity about polypharmacy in older people through a sex and gender lens
Related: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject) AND Polypharmacy Management in Older Patients – Mayo Clinic Proceedings AND Psychopharmacological Treatment in Older People: Avoiding Drug Interactions and Polypharmacy – Deutsches Ärzteblatt internationa AND Eliminating Medication Overload: A National Action Plan AND Deprescribing in Older Adults With Cardiovascular Disease – Journal of the American College of Cardiology
Commentary on Twitter
NEW REVIEW: @RochonPaula and colleagues look at #polypharmacy & #deprescribing for #older people through a sex & gender lens
👀Read the #openaccess paper here: https://t.co/CpcJswOtt1
👂Listen to the new podcast with the authors here:https://t.co/EXg9wNlE9K pic.twitter.com/AZ4VkKt33p— The Lancet Healthy Longevity (@LancetLongevity) May 13, 2021
Simplified decision aid: neuropathic pain treatment options in primary care.
14 May, 2021 | 08:17h | UTC
Systematic review: Treatments for unruptured intracranial aneurysms – There is currently insufficient good-quality evidence to support either conservative treatment or interventional treatments (microsurgical clipping or endovascular coiling)
13 May, 2021 | 05:51h | UTCTreatments for unruptured intracranial aneurysms – Cochrane Library
Summary: Treatments for unruptured intracranial aneurysms – Cochrane Library
Review: Diagnosis and treatment of unruptured intracranial aneurysms and aneurysmal subarachnoid hemorrhage
13 May, 2021 | 05:53h | UTC
Eight out of ten people hospitalized with COVID-19 develop neurological problems – the most common self-reported symptoms included headache (37%) and anosmia or ageusia (26%).
12 May, 2021 | 08:55h | UTC
Review: Diagnosis and management of headache.
12 May, 2021 | 08:36h | UTCDiagnosis and Management of Headache: A Review – JAMA (free for a limited period)
Audio clinical review: Diagnosis and Management of Headache, Part 1 – JAMA
Review: Neurologic assessment of the neurocritical care patient.
12 May, 2021 | 08:24h | UTCNeurologic Assessment of the Neurocritical Care Patient – Frontiers in Neurology
Population-based cohort study: Youngest children in class are more likely to be diagnosed with a learning disability
11 May, 2021 | 09:08h | UTCCommentary: Youngest children in class are more likely to be diagnosed with a learning disability – University of Turku
Guideline: Diagnosis and treatment of neurogenic dysphagia.
6 May, 2021 | 08:51h | UTC
Management of the Patient With Patent Foramen Ovale in 2021: A Spectrum of Cases
5 May, 2021 | 08:15h | UTC
[Preprint] Frequency of neurological manifestations in COVID-19: a systematic review and meta-analysis of 350 studies – up to one-third of COVID-19 patients analyzed in this review, 89% of whom were hospitalized, experienced at least one neurological manifestation
4 May, 2021 | 08:44h | UTCCommentary: Study finds one-third of COVID-19 patients experience neurological symptoms – News Medical
M-A: A third of kids develop a mental health problem after concussion
4 May, 2021 | 08:35h | UTCNews Release: A third of kids develop a mental health problem after concussion – Murdoch Childrens Research Institute
Original Study: Mental health after paediatric concussion: a systematic review and meta-analysis – British Journal of Sports Medicine
Review: Parkinson’s disease
4 May, 2021 | 08:28h | UTCParkinson’s disease – The Lancet
Cohort Study: The risk of overdose with concomitant use of Z-Drugs (zolpidem, zopiclone, zaleplon) and prescription opioids is significantly increased
30 Apr, 2021 | 08:32h | UTCThe Risk of Overdose With Concomitant Use of Z-Drugs and Prescription Opioids: A Population-Based Cohort Study – American Journal of Psychiatry (link to abstract – $ for full-text)
Commentary: Co-prescribing Opioids, Z-Drugs May Increase Risk of Overdose – Psychiatric News Alert
AHA/ASA Guidance: Diagnosis and Management of Cerebral Venous Sinus Thrombosis with Vaccine-Induced Thrombotic Thrombocytopenia – “No heparin products in any dose should be given.”
30 Apr, 2021 | 08:25h | UTCNews release: Guidance on treatment for rare blood clots and low platelets related to COVID-19 vaccine – American Heart Association
COVID-19 ‘brain fog’ inspires search for causes and treatments
30 Apr, 2021 | 08:13h | UTCCOVID-19 ‘brain fog’ inspires search for causes and treatments – Science (a few articles per month are free)
Clinical Manifestation, Evaluation, and Rehabilitative Strategy of Dysphagia Associated With COVID-19
27 Apr, 2021 | 08:29h | UTC
Clinical review of 43 patients with COVID-19-associated Acute Transverse Myelitis and 3 patients with Acute Transverse Myelitis reported post-vaccination
27 Apr, 2021 | 08:32h | UTCCommentary: Rare neurological condition linked to COVID-19 cases in 21 countries – Houston Methodist
SARS-CoV-2 and Stroke Characteristics – higher rate of large vessel occlusions and stroke in young patients
25 Apr, 2021 | 22:01h | UTC
Commentary on Twitter
SARS-CoV-2 and #Stroke Characteristics: A Report From the Multinational COVID-19 Stroke Study Group #COVID19 #AHACOVID19 #AHAJournals @cgriessenauer @ArKatsanos https://t.co/Errp6MjQMV pic.twitter.com/QX5tAGQOXU
— Stroke AHA/ASA (@StrokeAHA_ASA) April 21, 2021
RCT: Promising results with vagus nerve stimulation paired with rehabilitation for upper limb motor function after ischemic stroke
25 Apr, 2021 | 21:10h | UTCCommentary: Vagus nerve stimulation: a potential new treatment for ischaemic stroke – The Lancet
Commentary on Twitter
Very important @TheLancet study showing #vagus nerve stimulation improves rehabilitation ischemic #stroke.
Kudos Prof Jesse Dawson @UofGlasgow at colleagues!https://t.co/DsIH3wMuAp pic.twitter.com/QtzBBDVnso
— Prof. Kevin J. Tracey, MD (@KevinJTraceyMD) April 23, 2021
Case series of 18 male adults aged 50 years or younger with acute ischemic stroke during the convalescent phase of asymptomatic Covid-19
23 Apr, 2021 | 08:39h | UTC
Commentary on Twitter
A 💥🆕 case series highlights that adults 50 years or younger with asymptomatic COVID-19 infection diagnosed by positive SARS-CoV-2 serological test result may present with ischemic stroke during the convalescent phase of the infection
https://t.co/BVlo7Z1hgn @JAMANetworkOpen— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) April 22, 2021