Neurology
RCT | Intrathecal Tofersen did not improve clinical endpoints in patients with amyotrophic lateral sclerosis with mutations in SOD1.
27 Sep, 2022 | 13:09h | UTCTrial of Antisense Oligonucleotide Tofersen for SOD1 ALS – New England Journal of Medicine (link to abstract – $ for full-text)
M-A | Association of gestational diabetes mellitus with cardiovascular and cerebrovascular diseases.
26 Sep, 2022 | 12:01h | UTCNews Release: Diabetes in pregnancy linked to risk of cardiovascular and cerebrovascular disease – BMJ Newsroom
Commentary on Twitter
Gestational diabetes mellitus is associated with increased risks of overall and type specific cardiovascular and cerebrovascular diseases that cannot be solely attributed to conventional cardiovascular risk factors or subsequent diabetes, finds new studyhttps://t.co/0fCIXKVK99
— The BMJ (@bmj_latest) September 22, 2022
Series | Sleep and sleep disorders.
23 Sep, 2022 | 13:13h | UTCHomepage: Sleep and sleep disorders (free registration required for all articles)
Editorial: Waking up to the importance of sleep
Series:
Understanding and approaching excessive daytime sleepiness
Circadian rhythms and disorders of the timing of sleep
Sleep function: an evolutionary perspective
Commentaries:
How and why do human beings sleep?
Social determinants and health disparities affecting sleep
Guideline Synopsis | Management of major depressive disorder.
21 Sep, 2022 | 13:23h | UTC
Sodium and water perturbations in patients who had an acute stroke: clinical relevance and management strategies for the neurologist.
21 Sep, 2022 | 13:06h | UTC
RCT | Efficacy and safety of Rituximab for new onset generalized Myasthenia Gravis.
21 Sep, 2022 | 13:04h | UTC
Commentary on Twitter
Treatment with #rituximab shortly after onset of #myastheniagravis was effective, a placebo-controlled randomized study showed. https://t.co/wdUzx7yOq6 #Research
— JAMA Neurology (@JAMANeuro) September 19, 2022
Encephalitis: diagnosis, management and recent advances in the field of encephalitides.
21 Sep, 2022 | 13:05h | UTC
RCTs | Crenezumab not beneficial for patients with early Alzheimer Disease.
21 Sep, 2022 | 13:03h | UTC
Guideline on pharmacological interventions for long-term secondary prevention after ischemic stroke or transient ischemic attack.
20 Sep, 2022 | 13:27h | UTCEuropean Stroke Organisation (ESO) guideline on pharmacological interventions for long-term secondary prevention after ischaemic stroke or transient ischaemic attack – European Stroke Journal (free for a limited period)
Guidelines on treatment of patients with intracranial atherosclerotic disease.
20 Sep, 2022 | 13:26h | UTCEuropean Stroke Organisation guidelines on treatment of patients with intracranial atherosclerotic disease – European Stroke Journal (free for a limited period)
Guidelines on management of unruptured intracranial aneurysms.
20 Sep, 2022 | 13:25h | UTCEuropean Stroke Organisation (ESO) guidelines on management of unruptured intracranial aneurysms – European Stroke Journal (free for a limited period)
Guideline on screening for subclinical atrial fibrillation after stroke or transient ischemic attack of undetermined origin.
20 Sep, 2022 | 13:25h | UTCEuropean Stroke Organisation (ESO) guideline on screening for subclinical atrial fibrillation after stroke or transient ischaemic attack of undetermined origin – European Stroke Journal (free for a limited period)
RCT | Cerebral embolic protection during transcatheter aortic-valve replacement did not significantly reduce the incidence of periprocedural stroke.
19 Sep, 2022 | 12:49h | UTCCerebral Embolic Protection during Transcatheter Aortic-Valve Replacement – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries:
PROTECTED TAVR: No Less Stroke With Embolic Protection, but Some See Hope – TCTMD
Presumed Clinical Benefits of TAVR Cerebral Protection Remain Unproven — Large trial comes up short in proving a definitive benefit to debris filters – MedPage Today (free registration required)
News Release: Cerebral Embolic Protection During Transcatheter Aortic-Valve Replacement – Cedars-Sinai
Commentary on Twitter
In a randomized trial involving patients with aortic stenosis, the use of a cerebral protection device during TAVR did not decrease the risk of periprocedural stroke, but there were fewer disabling strokes. #TCT2022 https://t.co/wBgNlgmIty pic.twitter.com/EViLG19shX
— NEJM (@NEJM) September 17, 2022
Cohort Study | Seven healthy lifestyle habits linked to reduced risk of dementia in people with diabetes.
19 Sep, 2022 | 12:45h | UTCAssociation of Combined Healthy Lifestyle Factors With Incident Dementia in Patients With Type 2 Diabetes – Neurology (link to abstract – $ for full-text)
News Release: Seven healthy lifestyle habits may reduce dementia risk for people with diabetes – American Academy of Neurology
Commentary: Lifestyle Factors May Cut Dementia Risk in Patients With Diabetes – HealthDay
Cohort Study | Incidence of antipsychotic use among community dwellers with and without Parkinson’s disease.
14 Sep, 2022 | 13:07h | UTCCommentaries:
Elevated Incidence of Antipsychotic Use Found Prior to Parkinson Disease Diagnosis – AJMC
Antipsychotics Use Climbs in Years Before Parkinson’s Diagnosis: Study – Parkinson’s News Today
Dementia: evidence, experience and resources.
13 Sep, 2022 | 13:20h | UTCDementia: evidence, experience and resources – Evidently Cochrane
M-A | Blood type linked to the risk of stroke before age 60.
13 Sep, 2022 | 13:17h | UTCContribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke – Neurology (link to abstract – $ for full-text)
News Releases:
Is your blood type linked to your risk of stroke before age 60? – American Academy of Neurology
Blood Type Linked To Stroke Risk Before 60 – University of Maryland
Radiological assessment of dementia | Consensus for a practical and clinically oriented guide to image acquisition, evaluation, and reporting.
13 Sep, 2022 | 13:13h | UTC
Practical Recommendations | How to deal with sleep problems during heat waves.
11 Sep, 2022 | 23:00h | UTCCommentary: How to sleep in a heat wave, according to experts – CNN
Early versus delayed non–vitamin k antagonist oral anticoagulant therapy after acute ischemic stroke in atrial fibrillation: a registry-based randomized controlled noninferiority study.
8 Sep, 2022 | 14:46h | UTCEarly Versus Delayed Non–Vitamin K Antagonist Oral Anticoagulant Therapy After Acute Ischemic Stroke in Atrial Fibrillation (TIMING): A Registry-Based Randomized Controlled Noninferiority Study – Circulation (free for a limited period)
Commentary on Twitter
Congrats to my good friend/colleague @BoNorrving for the TIMING study! Starting NOAC after stroke d/t AF <4 d is safe (no ICH) and = or better than 5-10 d. Registry-based, pragmatic, investigator led, PROBE design. High value = science first approach.
https://t.co/35qiZ5Ivoa— Dr. Lee Schwamm (@Braindoc_MGH) September 7, 2022
Severe prognoses for intracerebral and intraventricular hemorrhage may greatly underestimate functional recovery.
8 Sep, 2022 | 14:28h | UTCOriginal Study: One-Year Outcome Trajectories and Factors Associated with Functional Recovery Among Survivors of Intracerebral and Intraventricular Hemorrhage With Initial Severe Disability – JAMA Neurology (link to abstract – $ for full-text)
Commentary on Twitter
In this cohort study, nearly half of the survivors of intracerebral hemorrhage with poor-outcome in the early-phase recovered to a good outcome by 1-year. Including first 30-day events in prognostic models improved prediction of recovery. https://t.co/uQ7IqxCqBD
— JAMA Neurology (@JAMANeuro) July 25, 2022
Stroke–heart syndrome: recent advances and challenges.
7 Sep, 2022 | 12:35h | UTCStroke–Heart Syndrome: Recent Advances and Challenges – Journal of the American Heart Association
Commentary on Twitter
Proud to share our updated review about the stroke-heart syndrome. Read more about recent advances on how brain ischemia can trigger cardiac events. https://t.co/ywJs2JbZht Many thanks to @SposatoL, @JohannesBacks and @Dr_No_Charite for your contribution! #brainheart #strokeheart pic.twitter.com/3IV9LU7fJN
— Jan Scheitz 🧠⚡️❤️ (@Jan_FriSch) September 3, 2022
Under a Creative Commons Attribution‐Non Commercial‐No Derivs License
Predictive role of atrial fibrillation in cognitive decline: a systematic review and meta-analysis of 2.8 million individuals.
7 Sep, 2022 | 12:30h | UTC
Commentary on Twitter (thread – click for more)
AF associated with ⬆️ risk of cognitive impairment 👉
📌 HR 1.39 general 👫
📌 HR 2.70 post-stroke 👫@natale_md @TJaredBunch @Dr_Santangeli @JonPicciniSr @DrMarthaGulati @rafavidalperez @DhirajGuptaBHRS @SABOURETCardio @iamritu @Hragy @mmamas1973 @SeguraCardio @cpgale3 #afib pic.twitter.com/dZxkd7G1wc— Raviele Antonio (@drraviele) January 21, 2022
Under a https://creativecommons.org/licenses/by/4.0/ license
Systematic Review | Opioid agonist treatment for people who are dependent on pharmaceutical opioids.
6 Sep, 2022 | 14:31h | UTCOpioid agonist treatment for people who are dependent on pharmaceutical opioids – Cochrane Library
Systematic Review | Global frequency and clinical features of stroke in patients with tuberculous meningitis.
6 Sep, 2022 | 14:19h | UTC