Internal Medicine
M-A | Efficacy of a restrictive diet in irritable bowel syndrome.
2 Aug, 2022 | 12:02h | UTCCommentary: Gluten-Free, Low FODMAP Diets Beneficial for IBS Symptoms – HCPLive
Related:
10 mistakes in dietary management of irritable bowel syndrome and how to avoid them.
Supplement: Irritable bowel syndrome and related conditions.
RCT: FODMAPs, but not gluten, elicit modest symptoms of irritable bowel syndrome.
British Society of Gastroenterology guidelines on the management of irritable bowel syndrome
Guidelines for the treatment of irritable bowel syndrome
ACG Clinical Guideline: Management of irritable bowel syndrome
M-A: Efficacy of a low-FODMAP diet in adult irritable bowel syndrome
Review | Management of liver decompensation in advanced liver disease (renal impairment, liver failure, adrenal insufficiency, cardiopulmonary complications).
2 Aug, 2022 | 11:48h | UTC
Review | Cutaneous manifestations of acute kidney injury.
2 Aug, 2022 | 11:46h | UTCCutaneous manifestations of acute kidney injury – Clinical Kidney Journal
Review | Sciatica mimics.
2 Aug, 2022 | 11:54h | UTC
Review | Treatment of acute kidney injury in cancer patients.
2 Aug, 2022 | 11:43h | UTCTreatment of acute kidney injury in cancer patients – Clinical Kidney Journal
Related:
Onconephrology: Update in Anticancer Drug-Related Nephrotoxicity – Nephron
RCT | Intervention with methotrexate in patients with arthralgia at risk of rheumatoid arthritis to reduce the development of persistent arthritis and its disease burden.
1 Aug, 2022 | 12:32h | UTCIntervention with methotrexate in patients with arthralgia at risk of rheumatoid arthritis to reduce the development of persistent arthritis and its disease burden (TREAT EARLIER): a randomised, double-blind, placebo-controlled, proof-of-concept trial – The Lancet (link to abstract – $ for full-text)
News Release: Treatment before patients develop rheumatism provides lasting relief – Leiden University Medical Centre
Commentaries on Twitter:
NEW in @TheLancet—The TREAT EARLIER trial shows that #methotrexate initiated in patients with arthralgia at risk of #rheumatoidarthritis did not prevent the development of clinical arthritis, but did modify the disease course https://t.co/5zh7lqb4NJ pic.twitter.com/lJflW9Prwm
— The Lancet Rheumatology (@TheLancetRheum) July 22, 2022
🆕🔥Methotrexate,🇳🇱study
MTX in pre-arthritis stage➡️ did not prevent the development of clinical arthritis
but ➡️sustained improvement in
♦️MRI-detected inflammation,
♦️Symptoms (Pain & EMS)
♦️Related impairments (HAQ n Presentism)
Vs placebohttps://t.co/I0IdKydPME pic.twitter.com/cNi6AhO151— EnvisionRheumat (@ERheumat) July 29, 2022
RCT | Endoscopic sleeve gastroplasty for treatment of class 1 and 2 obesity.
1 Aug, 2022 | 12:35h | UTCEndoscopic sleeve gastroplasty for treatment of class 1 and 2 obesity (MERIT): a prospective, multicentre, randomised trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
MERIT trial suggests endoscopic sleeve gastroplasty should be considered as a synergistic weight loss intervention for patients with class 1 or class 2 obesity.
Find out more: https://t.co/FWeXeWbBF0 pic.twitter.com/W6qUKW92hR
— The Lancet (@TheLancet) July 30, 2022
Brief Review | Monitoring pain in the intensive care unit.
1 Aug, 2022 | 12:30h | UTCMonitoring pain in the intensive care unit (ICU) – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
Monitoring pain in #ICU
➡️ self‐assessment tools in pts able to self‐report
➡️ observational behavioural scales in pts unable to self‐report
➡️ physiologic parameters in pts unable to self‐report nor express behaviours (deep sedaution, NMBAs)#FOAMcc
🖇 https://t.co/SaD1BBxSNw pic.twitter.com/81tNNvnTDe— Intensive Care Medicine (@yourICM) July 30, 2022
Cohort Study | Long-term leisure-time physical activity intensity and all-cause and cause-specific mortality.
1 Aug, 2022 | 12:26h | UTCLong-Term Leisure-Time Physical Activity Intensity and All-Cause and Cause-Specific Mortality: A Prospective Cohort of US Adults – Circulation (free for a limited period)
News Release: New study finds lowest risk of death was among adults who exercised 150-600 minutes/week – American Heart Association
WHO chief advises men who have sex with men to reduce partners to limit exposure to monkeypox.
1 Aug, 2022 | 12:24h | UTCWHO chief advises men who have sex with men to reduce partners to limit exposure to monkeypox – CNN
See also: WHO recommends gay and bisexual men limit sexual partners to reduce the spread of monkeypox – CNBC
Related:
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
Commentary on Twitter
The #monkeypox outbreak can be stopped if countries, communities and individuals inform themselves, take the risks seriously, and take the steps needed to stop transmission and protect vulnerable groups.pic.twitter.com/7CumPFyPhc
— Tedros Adhanom Ghebreyesus (@DrTedros) July 27, 2022
Perspective | Aspirin for the primary prevention of atherosclerotic cardiovascular disease in women.
1 Aug, 2022 | 12:25h | UTCAspirin for the Primary Prevention of Atherosclerotic Cardiovascular Disease in Women – JAMA (free for a limited period)
Monkeypox | A contemporary review for healthcare professionals.
1 Aug, 2022 | 12:20h | UTCMonkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
Related:
WHO chief advises men who have sex with men to reduce partners to limit exposure to monkeypox – CNN
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Clinical features and novel presentations of human monkeypox in a central London center during the 2022 outbreak: descriptive case series.
1 Aug, 2022 | 12:22h | UTCRelated:
WHO chief advises men who have sex with men to reduce partners to limit exposure to monkeypox – CNN
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
Commentary on Twitter
NEW research published by The BMJ today identifies important differences in monkeypox symptoms between the current outbreak and previous outbreaks in endemic regions https://t.co/uYnhbZoBhd pic.twitter.com/NZNoNVi6Lm
— The BMJ (@bmj_latest) July 29, 2022
M-A | Respiratory support strategy in adults with acute hypoxemic respiratory failure.
1 Aug, 2022 | 12:18h | UTC
Review | Management of heart failure in patients with chronic kidney disease.
1 Aug, 2022 | 11:59h | UTCManagement of Heart Failure in Patients with Chronic Kidney Disease – European Cardiology Review
Cohort Study | Rapid loss of smell predicts dementia and smaller brain areas linked to Alzheimer’s.
1 Aug, 2022 | 11:49h | UTCNews Release: Rapid loss of smell predicts dementia and smaller brain areas linked to Alzheimer’s – University of Chicago Medical Center
Original Study: Rapid olfactory decline during aging predicts dementia and GMV loss in AD brain regions – Alzheimer’s & Dementia
Systematic Review | Rapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection.
29 Jul, 2022 | 12:39h | UTCRapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection – Cochrane Library
Summary: How accurate are rapid antigen tests for diagnosing COVID-19? – Cochrane Library
M-A | Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes.
29 Jul, 2022 | 12:37h | UTCCommentaries:
No justification for bespoke antihypertensive intervention in type 2 diabetes – medwire News
Blood pressure control according to type 2 diabetes status – The Lancet Diabetes & Endocrinology (free registration required)
Commentary on Twitter
Online—Blood pressure-lowering treatment for prevention of major #cardiovascular diseases in people with and without type 2 #diabetes: an individual participant-level data meta-analysis https://t.co/AmNxyW9Via #T2D #BloodPressure #hypertension #openaccess pic.twitter.com/NfdLktZXai
— The Lancet Diabetes & Endocrinology (@TheLancetEndo) July 25, 2022
Position Paper | Red yeast rice for dyslipidemias and cardiovascular risk reduction.
29 Jul, 2022 | 12:35h | UTC
Systematic Review | Antiplatelet agents and anticoagulants for hypertension.
29 Jul, 2022 | 12:29h | UTCAntiplatelet agents and anticoagulants for hypertension – Cochrane Library
Summary: Antiplatelet agents and anticoagulants for high blood pressure – Cochrane Library
Commentary on Twitter
Do #antiplatelet agents & #anticoagulants improve outcomes in people with #hypertension?
Our newly updated @CochraneLibrary review looks at the evidence of 6 RCTs involving more than 61,000 participants: https://t.co/zaXP4YLg4n#CochraneEvidence #blogshot pic.twitter.com/X1DK2NTCtb
— Cochrane Hypertension (@CochraneHTN) July 28, 2022
Cohort Study | Analysis of prescriptions for dual antiplatelet therapy after acute ischemic stroke.
29 Jul, 2022 | 12:20h | UTCRelated:
Commentary on Twitter
In this cohort study, dual antiplatelet of aspirin and clopidogrel was underused in patients with minor ischemic stroke and potentially overused in non-minor ischemic stroke, with substantial hospital variations. https://t.co/rZeGbMgF1E
— JAMA Network Open (@JAMANetworkOpen) July 28, 2022
RCT | Supplemental Vitamin D does not reduce incident fractures in midlife and older adults.
28 Jul, 2022 | 13:31h | UTCSupplemental Vitamin D and Incident Fractures in Midlife and Older Adults – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Daily Vitamin D supplements don’t lower risk of bone fractures, study finds – STAT
Related:
Commentary on Twitter
A study ancillary to a large trial showed that supplemental vitamin D3 did not lower the risk of fractures among generally healthy midlife and older adults not selected for vitamin D deficiency, low bone mass, or osteoporosis. https://t.co/vVTlizdffG pic.twitter.com/hQHJ7JizaV
— NEJM (@NEJM) July 27, 2022
M-A | Prognosis and persistence of smell and taste dysfunction in patients with covid-19.
28 Jul, 2022 | 13:28h | UTCEditorial: Smell and taste dysfunction after covid-19 – The BMJ
Commentary: The burden of prolonged smell and taste loss in covid-19 – The BMJ
News Release: Millions of covid patients may have long term smell and taste problems – BMJ Newsroom
M-A | Nonoperative vs. operative management of uncomplicated acute appendicitis.
28 Jul, 2022 | 13:30h | UTCNonoperative vs Operative Management of Uncomplicated Acute Appendicitis: A Systematic Review and Meta-Analysis – JAMA Surgery (free for a limited period)
Related:
Review: Diagnosis of uncomplicated and complicated appendicitis in adults.
A Randomized trial comparing antibiotics with appendectomy for appendicitis
Commentary on Twitter
Nonoperative management with #antibiotics may be an alternative option to appendectomy in adult patients with uncomplicated acute #appendicitis, noting the possibility of longer hospital stays and potentially higher rates of recurrent appendicitis. https://t.co/4RbzU8SC8i
— JAMA Surgery (@JAMASurgery) July 27, 2022
RCT | Effects of walking exercise at a pace with vs. without ischemic leg symptoms on functional performance measures in people with lower extremity peripheral artery disease.
28 Jul, 2022 | 13:27h | UTCNews Release: ‘No pain, no gain’ approach improves walking ability with peripheral artery disease – American Heart Association