Internal Medicine
Systematic Review: Efficacy of antiviral therapies for COVID-19.
15 Feb, 2022 | 10:02h | UTC
Covid-19: Fourth vaccine doses—who needs them and why?
15 Feb, 2022 | 09:59h | UTCCovid-19: Fourth vaccine doses—who needs them and why? – The BMJ
A practical guide to the evaluation of small bowel bleeding.
15 Feb, 2022 | 09:49h | UTCA Practical Guide to the Evaluation of Small Bowel Bleeding – Mayo Clinic Proceedings
Cluster Randomized Clinical Trial: An electronic decision support system for deprescribing in hospitalized older adults was safe and led to improvements in deprescribing but did not reduce adverse drug events.
15 Feb, 2022 | 09:43h | UTC
Commentary on Twitter
Randomized control trial found that @MedSaferTool increases #deprescribing by 22% at hospital discharge but little impact on short term adverse drug events. https://t.co/XqiSwFSPEz @DrEmilyMcD @DrToddLee @DeprescribeUS
— JAMA Internal Medicine (@JAMAInternalMed) January 18, 2022
Review: Classic and exertional heatstroke.
15 Feb, 2022 | 08:43h | UTCClassic and exertional heatstroke – Nature Reviews Disease Primers (if the link is paywalled, try this one)
Commentary on Twitter
Cooling of patients with #heatstroke includes evaporative strategies and conductive methods that aim to establishing the largest possible temperature gradient between the body core and the skin https://t.co/i53jyJBTl5 pic.twitter.com/tofUjiDJYG
— Nature Reviews Disease Primers (@DiseasePrimers) February 8, 2022
A large cohort of patients with nephrotic syndrome showed the risk of arterial thromboembolism (HR = 3.11), venous thromboembolism (HR = 7.11), and bleeding (HR = 4.02) was greatly increased after adjusting for confounders.
15 Feb, 2022 | 08:47h | UTCRisk of arterial thromboembolism, venous thromboembolism, and bleeding in patients with nephrotic syndrome: A population-based cohort study – American Journal of Medicine (link to abstract – $ for full-text)
WHO’s new International Classification of Diseases (ICD-11) comes into effect.
13 Feb, 2022 | 22:56h | UTCNews Release: WHO’s new International Classification of Diseases (ICD-11) comes into effect – World Health Organization
See also:
Commentary on Twitter
🆕 The latest update for the 11th Revision of the International Classification of Diseases (ICD-11) is now online!#ICD11 is a 'common language' for health professionals to share standardized health information around the world.
Learn more https://t.co/M2yu9md9fm pic.twitter.com/jv2IbEkD5u— World Health Organization (WHO) (@WHO) February 11, 2022
Conflicting reports raise questions about whether any monoclonals work against Omicron’s sister variant.
13 Feb, 2022 | 22:49h | UTCRelated:
FDA halts use of antibody drugs that don’t work vs. Omicron.
ERS statement on Long COVID-19 follow-up.
13 Feb, 2022 | 22:48h | UTCEuropean Respiratory Society Statement on Long COVID-19 Follow-Up – European Respiratory Review
Special Issue: Evidence-based strategies for better antibiotic prescribing in primary care.
13 Feb, 2022 | 22:40h | UTCEditorial: Antibiotic stewardship – Australian Journal of General Practice
Evidence-based strategies for better antibiotic prescribing – Australian Journal of General Practice
RCT: Effects of a 6-month, low-carbohydrate diet on glycemic control, body composition, and cardiovascular risk factors in patients with type 2 diabetes.
13 Feb, 2022 | 22:35h | UTC
RCT: Primary Norfloxacin prophylaxis prevents bacterial infections in patients with acute-on-chronic liver failure.
13 Feb, 2022 | 22:37h | UTCPrimary Norfloxacin Prophylaxis for APASL-Defined Acute-on-Chronic Liver Failure: A Placebo-Controlled Double-Blind Randomized Trial – The American Journal of Gastroenterology (link to abstract – $ for full-text)
WHO Guideline: Hypertension pharmacological treatment in adults.
13 Feb, 2022 | 22:23h | UTC
Opinion: Time to retire the concept of Transient Ischemic Attack.
13 Feb, 2022 | 22:01h | UTCTime to Retire the Concept of Transient Ischemic Attack – JAMA (free for a limited period)
Commentary on Twitter
After spending my entire career studying TIAs, Don Easton and I are recommending we retire the term. It isn't clear that TIAs ever existed, at least as they were conceptualized. Rise up Acute Ischemic Cerebrovascular Event/Syndrome. https://t.co/FeG31pPHey
— Clay Johnston (@ClayJohnstonMD) February 11, 2022
Review: Management of venous thromboembolism in pregnancy.
13 Feb, 2022 | 21:57h | UTCManagement of venous thromboembolism in pregnancy – Thrombosis Research
Related:
Management of high-risk pulmonary embolism in pregnancy.
Study: Diagnosis of Pulmonary Embolism During Pregnancy
Imaging is the only way to diagnose blood clots in pregnancy
IDSA guidance and ESCMID guidelines: complementary approaches toward a care standard for MDR Gram-negative infections.
11 Feb, 2022 | 08:51h | UTCOriginal Guidelines:
IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections.
AHA Scientific Statement | How does cannabis use affect brain health? Caution advised, more research needed.
11 Feb, 2022 | 08:53h | UTCNews Release: How does cannabis use affect brain health? Caution advised, more research needed – American Heart Association
Original Statement: Use of Marijuana: Effect on Brain Health: A Scientific Statement From the American Heart Association – Stroke
Related: AHA Scientific statement: Medical marijuana, recreational cannabis, and cardiovascular health
Commentary on Twitter
Use of Marijuana: Effect on Brain Health: A Scientific Statement From the American Heart Association #BrainHealth #ISC22 #AHAJournals https://t.co/LoGbVRfzf4 @American_Heart pic.twitter.com/DyNbFzA0Lw
— Stroke AHA/ASA (@StrokeAHA_ASA) February 10, 2022
RCT: In patients with acute stroke with a large ischemic region, endovascular therapy resulted in better functional outcomes compared to medical care alone but was associated with increased risk of intracranial hemorrhage.
11 Feb, 2022 | 08:49h | UTCEndovascular Therapy for Acute Stroke with a Large Ischemic Region – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Endovascular Stroke Therapy Works for Large Infarcts: RESCUE-Japan LIMIT – TCTMD
Recovering from a pandemic: pulmonary fibrosis after SARS-CoV-2 infection.
11 Feb, 2022 | 08:44h | UTC
Management of Mycobacterium avium complex and Mycobacterium abscessus pulmonary disease: therapeutic advances and emerging treatments.
11 Feb, 2022 | 08:29h | UTC
Review: Diagnosis, course and management of hypersensitivity pneumonitis.
11 Feb, 2022 | 08:30h | UTCDiagnosis, course and management of hypersensitivity pneumonitis – European Respiratory Review
Discontinuing antidepressants: Pearls and pitfalls.
11 Feb, 2022 | 08:18h | UTCDiscontinuing antidepressants: Pearls and pitfalls – Cleveland Clinic Journal of Medicine
Evaluation and management of orthostatic hypotension: Limited data, limitless opportunity.
11 Feb, 2022 | 08:21h | UTC
M-A: The prevalence of loneliness across 113 countries.
10 Feb, 2022 | 10:08h | UTCThe prevalence of loneliness across 113 countries: systematic review and meta-analysis – The BMJ
Editorial: We need a public health approach to loneliness
News Release: Problematic levels of loneliness widespread in many countries – BMJ
Commentary on Twitter
https://twitter.com/robert_eres/status/1491663838013702144
Clinical Review: Advances in the management of cardioembolic stroke associated with patent foramen ovale.
10 Feb, 2022 | 10:17h | UTCAdvances in the management of cardioembolic stroke associated with patent foramen ovale – The BMJ
Related:
Management of the Patient With Patent Foramen Ovale in 2021: A Spectrum of Cases


