Internal Medicine
Still coughing after COVID? Here’s why it happens and what to do about it.
1 Apr, 2022 | 09:50h | UTCStill coughing after COVID? Here’s why it happens and what to do about it – The Conversation
Viewpoint: Evaluating the effectiveness of diagnostic tests.
1 Apr, 2022 | 09:47h | UTCEvaluating the Effectiveness of Diagnostic Tests – JAMA (free for a limited period)
Body-mass index and risk of obesity-related complex multimorbidity: an observational multicohort study.
1 Apr, 2022 | 08:49h | UTCInvited Commentary: The actual burden of obesity—accounting for multimorbidity – The Lancet Diabetes & Endocrinology (free registration required)
Commentary on Twitter
In the April Issue:
Body-mass index and risk of #obesity-related complex #multimorbidity: an observational multicohort study https://t.co/I2AqM9FmKd #BMI #OpenAccess pic.twitter.com/36f7J5VDZU— The Lancet Diabetes & Endocrinology (@TheLancetEndo) March 30, 2022
M-A: Impact of enhanced recovery pathways on safety and efficacy of hip and knee arthroplasty.
1 Apr, 2022 | 08:31h | UTCRelated:
Review: Enhanced recovery after surgery for major orthopedic surgery.
Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines (some guidelines are free)
Practice review: Evidence-based and effective management of anemia in palliative care patients.
1 Apr, 2022 | 08:21h | UTC
Practice review: Evidence-based management approaches for patients with severe chronic obstructive pulmonary disease (COPD).
1 Apr, 2022 | 08:29h | UTC
Practice review: Evidence-based and effective management of fatigue in patients with advanced cancer.
1 Apr, 2022 | 08:26h | UTC
RCT: Early treatment with ivermectin does not improve outcomes in patients with Covid-19.
31 Mar, 2022 | 08:41h | UTCCommentary: Ivermectin does not prevent COVID-19 hospitalization, a new study says – NPR
Commentary on Twitter
Ivermectin: the largest randomized, double-blind trial yet conducted, with early treatment, indicates there is no difference compared with placebo. It doesn't work. Period. https://t.co/wiFygjRgkk
just published @NEJM pic.twitter.com/uZ0mMZnO0E— Eric Topol (@EricTopol) March 30, 2022
RCT: Early outpatient treatment with convalescent plasma reduces the risk of hospitalization in patients with Covid-19.
31 Mar, 2022 | 08:39h | UTCEarly Outpatient Treatment for Covid-19 with Convalescent Plasma – New England Journal of Medicine
Commentaries:
Early Use of High-Titer Plasma Reduced COVID Hospitalizations— Randomized trial that influenced indication shows benefits in a mostly unvaccinated population – MedPage Today (free registration required)
Commentary on Twitter
https://twitter.com/NEJM/status/1509278140433981444
USPSTF Draft Recommendation Statement: the current evidence is insufficient to recommend screening for obstructive sleep apnea in asymptomatic individuals.
31 Mar, 2022 | 08:42h | UTCCommentary: USPSTF: Evidence Lacking for OSA Screening in Asymptomatic Adults – HealthDay
Meta-analysis of randomized trials: Clopidogrel is better than aspirin for the secondary prevention of cardiovascular events.
31 Mar, 2022 | 08:31h | UTCCommentary: Clopidogrel Superior to ‘Divine’ Aspirin Monotherapy in Secondary Prevention – TCTMD
Commentary on Twitter
Happy to share our paper in @ESC_Journals. In this meta-analysis of randomized trials, we found that as compared with aspirin, P2Y12i was associated with 11% and 19% reduction in MACE and MI respectively. https://t.co/Y3Gstzgfu6
— Devika Aggarwal (@devikagg) March 30, 2022
M-A: Psychological interventions for chronic, non-specific low back pain.
31 Mar, 2022 | 08:20h | UTCNews Release: Study sheds light on psychological therapies for chronic low back pain – British Medical Journal
RCT: Effect of tacrolimus vs. intravenous cyclophosphamide on complete or partial response in patients with lupus nephritis.
31 Mar, 2022 | 08:18h | UTC
Commentary on Twitter
In this RCT, oral tacrolimus was noninferior to intravenous cyclophosphamide for initial therapy of active lupus nephritis, with a more favorable safety profile. https://t.co/scz7lahVRU
— JAMA Network Open (@JAMANetworkOpen) March 30, 2022
A Narrative Review on the approach to antimicrobial use in ventilated patients with multidrug resistant organisms in respiratory samples—to treat or not to treat?
31 Mar, 2022 | 08:27h | UTC
Commentary on Twitter
https://twitter.com/ABsteward/status/1508917245740818438
Association of computed tomography screening with lung cancer stage shift and survival in the United States: quasi-experimental study.
31 Mar, 2022 | 08:23h | UTCEditorial: Screening high risk populations for lung cancer
News Release: US lung cancer screening linked to earlier diagnosis and better survival – British Medical Journal
Related:
Screening for Lung Cancer: CHEST Guideline and Expert Panel Report.
Commentary on Twitter
Increases in the early detection of lung cancer since 2014 in the US have saved an estimated 10,100 lives, but screening rates are still extremely low and disparities in access to lung cancer screening continue to exist, say researchers https://t.co/j58LfcGCKU
— The BMJ (@bmj_latest) March 31, 2022
Cohort Study: Mortality associated with mental disorders and comorbid general medical conditions.
31 Mar, 2022 | 08:15h | UTCMortality Associated With Mental Disorders and Comorbid General Medical Conditions – JAMA Psychiatry
Commentary: People with Mental Disorders, General Comorbid Conditions Have 11-Year Reduced Life Expectancy – HCP Live
Review | Advanced heart failure: guideline-directed medical therapy, diuretics, inotropes, and palliative care.
31 Mar, 2022 | 08:09h | UTC
Systematic Review: Evidence-based efficacy of methotrexate in adult Crohn’s disease in different intestinal and extraintestinal indications.
31 Mar, 2022 | 07:50h | UTC
The incidence of adult-onset Type 1 Diabetes: a systematic review from 32 countries and regions.
31 Mar, 2022 | 07:52h | UTC
[Preprint] Retrospective cohort study: second booster vaccine and Covid-19 mortality in adults 60 to 100 years old.
30 Mar, 2022 | 10:44h | UTCSecond Booster Vaccine and Covid-19 Mortality in Adults 60 to 100 Years Old – Research Square
Commentaries:
Huge Study Finds Second COVID-19 Booster is ‘Life-saving’ for Over 60s – Health Policy Watch
Fourth COVID-19 vaccine dose substantially reduces mortality in the elderly – News Medical
U.S. approves second Covid-19 booster for people 50 and older and immunocompromised individuals.
30 Mar, 2022 | 10:42h | UTCU.S. approves second Covid-19 booster for people 50 and older – STAT
FDA OKs second COVID booster shot for older Americans – CIDRAP
Complicated and uncomplicated S. aureus bacteremia: an international Delphi survey among infectious diseases experts on definitions and treatment.
30 Mar, 2022 | 10:34h | UTC
The RECOVERY Trial – two years on.
30 Mar, 2022 | 10:38h | UTCThe RECOVERY Trial – two years on – University of Oxford
Related:
[Preprint] RECOVERY trial shows Baricitinib reduces deaths in patients hospitalized with COVID-19.
RECOVERY Trial: No benefit from convalescent plasma in patients admitted to hospital with COVID-19.
RECOVERY trial: Azithromycin not beneficial for patients admitted to hospital with COVID-19
RECOVERY trial: Effect of hydroxychloroquine in hospitalized patients with Covid-19
Randomized trial: Lopinavir–ritonavir not beneficial for patients admitted to hospital with COVID-19
Commentary on Twitter
https://twitter.com/MartinLandray/status/1508492188560371717
The harms of postoperative antibiotic prophylaxis: a teachable moment.
30 Mar, 2022 | 10:36h | UTCThe Harms of Postoperative Antibiotic Prophylaxis: A Teachable Moment – JAMA Internal Medicine (free for a limited period)
M-A: Parenchymal lung abnormalities following hospitalization for COVID-19 and viral pneumonitis.
30 Mar, 2022 | 10:26h | UTC


