RCT: Early outpatient treatment with convalescent plasma reduces the risk of hospitalization in patients with Covid-19.

Early Outpatient Treatment for Covid-19 with Convalescent Plasma – New England Journal of Medicine

Commentaries:

Study finds convalescent plasma can be effective early COVID-19 therapy – Johns Hopkins University School of Medicine

Early Use of High-Titer Plasma Reduced COVID Hospitalizations— Randomized trial that influenced indication shows benefits in a mostly unvaccinated population – MedPage Today (free registration required)

Commentary on Twitter

Fewer recipients of convalescent plasma had progression of Covid-19–associated illness leading to hospitalization. https://t.co/joa9ajpAcd pic.twitter.com/mHTnEHYN2O

— NEJM (@NEJM) March 30, 2022