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Infectious Diseases (all articles)

Ivermectin for COVID-19 Cochrane review update: 11 trials and no evidence of benefit shown.

23 Jun, 2022 | 10:38h | UTC

News Release: Ivermectin for COVID-19 review update: 11 trials and no evidence of benefit shown – Liverpool School of Tropical Medicine

Original Article: Ivermectin for preventing and treating COVID‐19 – Cochrane Library

Summary: Ivermectin for preventing and treating COVID-19 – Cochrane Library

 


Systematic Review: SARS‐CoV‐2‐neutralising monoclonal antibodies to prevent COVID‐19.

23 Jun, 2022 | 10:37h | UTC

SARS‐CoV‐2‐neutralising monoclonal antibodies to prevent COVID‐19 – Cochrane Library

Summary: Are laboratory-made COVID-19-specific monoclonal antibodies effective to prevent COVID-19 in adults? – Cochrane Library

 


Risk factors for SARS-CoV-2 related severe Multisystem Inflammatory Syndrome in Children investigated in a Swedish population-based study.

23 Jun, 2022 | 10:36h | UTC

News Release: Risk factors for severe COVID-19 complication in children investigated in Swedish population-based study – Karolinska Institutet

Original Study: Risk factors for multisystem inflammatory syndrome in children – A population-based cohort study of over 2 million children – The Lancet Regional Health Europe

 


M-A: Incidence and etiology of infant Gram-negative bacteremia and meningitis in children.

23 Jun, 2022 | 10:27h | UTC

Incidence and aetiology of infant Gram-negative bacteraemia and meningitis: systematic review and meta-analysis – Archives of Disease in Childhood

 


Systematic Review: Interventions to improve water, sanitation, and hygiene for preventing soil‐transmitted helminth infection.

23 Jun, 2022 | 10:09h | UTC

Interventions to improve water, sanitation, and hygiene for preventing soil‐transmitted helminth infection – Cochrane Library

Summary: Interventions to improve water, sanitation, and hygiene for preventing soil-transmitted helminth infection – Cochrane Library

 

Commentary from the author on Twitter

 


Systematic Review: Pyronaridine‐artesunate for treating uncomplicated Plasmodium falciparum malaria.

23 Jun, 2022 | 10:07h | UTC

Pyronaridine‐artesunate for treating uncomplicated Plasmodium falciparum malaria – Cochrane Library

Summary: Pyronaridine-artesunate for treating uncomplicated Plasmodium falciparum malaria – Cochrane Library

 


ASA and APSF statement on perioperative testing for the COVID-19 virus.

22 Jun, 2022 | 12:19h | UTC

ASA and APSF Statement on Perioperative Testing for the COVID-19 Virus – American Society of Anesthesiologists

Commentary: ASA, APST Update Perioperative SARS-CoV-2 Testing Recommendations – HealthDay

Related:

Surgical Triage and Timing for Patients with COVID: A Guidance Statement from the Society of Thoracic Surgeons – Annals of Thoracic Surgery

When to operate after SARS-CoV-2 infection? A review on the recent consensus recommendation of the DGC/BDC and the DGAI/BDA – Langenbeck’s Archives of Surgery

Guideline Update: Timing of elective surgery and risk assessment after SARS-CoV-2 infection – “The guidance remains that patients should avoid elective surgery within 7 weeks of infection, unless the benefits of doing so exceed the risk of waiting”.

Perioperative cardiovascular considerations prior to elective noncardiac surgery in patients with a history of Covid-19.

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

 


Cohort Study: Risk of myocarditis and pericarditis after the COVID-19 mRNA vaccination in the USA.

22 Jun, 2022 | 12:07h | UTC

Risk of myocarditis and pericarditis after the COVID-19 mRNA vaccination in the USA: a cohort study in claims databases – The Lancet

Commentaries:

COVID-19 mRNA vaccination and myocarditis or pericarditis – The Lancet

Myocarditis and Pericarditis After the COVID-19 mRNA Vaccination – American College of Cardiology

Related:

SARS-CoV-2 Vaccination and Myocarditis in a Nordic Cohort Study of 23 Million Residents – JAMA Cardiology

Myocarditis and pericarditis after COVID-19 vaccination: clinical management guidance for healthcare professionals – UK Health Security Agency

Myocarditis following a third Pfizer vaccination dose in military recruits in Israel.

Myocarditis following COVID-19 BNT162b2 vaccination among adolescents in Hong Kong.

[Preprint] Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy.

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

 


Review: SARS-CoV-2 infection and COVID-19 vaccination in pregnancy.

22 Jun, 2022 | 12:09h | UTC

SARS-CoV-2 infection and COVID-19 vaccination in pregnancy – Nature Reviews Immunology

 


Review: Sex differences in sequelae from COVID-19 infection and in long COVID syndrome.

22 Jun, 2022 | 12:06h | UTC

Sex differences in sequelae from COVID-19 infection and in long COVID syndrome: a review – Current Medical Research and Opinion

Commentary: Women more likely to have long COVID, different symptom profile – CIDRAP

 


Comparing the Pfizer and Moderna Covid vaccines for young children.

22 Jun, 2022 | 12:02h | UTC

Comparing the Pfizer and Moderna Covid vaccines for young children – STAT

Related: FDA advisers OK COVID-19 vaccines for youngest kids – CIDRAP

 


Position Paper: Diagnosis and management of infections caused by multidrug-resistant bacteria.

22 Jun, 2022 | 11:23h | UTC

A position paper for the diagnosis and management of infections caused by multidrug-resistant bacteria: Endorsed by the Italian Society of Infection and Tropical Diseases (SIMIT), the Italian Society of Anti-Infective Therapy (SITA), the Italian Group for Antimicrobial Stewardship (GISA), the Italian Association of Clinical Microbiologists (AMCLI), and the Italian Society of Microbiology (SIM) – International Journal of Antimicrobial Agents

Related Guideline:

IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections: Version 2.0 – Infectious Diseases Society of America

IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections: Version 1.0 – Infectious Diseases Society of America

 


RCT: Multispecies probiotic for the prevention of antibiotic-associated diarrhea in children.

22 Jun, 2022 | 11:12h | UTC

Multispecies Probiotic for the Prevention of Antibiotic-Associated Diarrhea in Children: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)

Commentary: Mixed Results With Probiotic for Kids’ Antibiotic-Related Diarrhea— Randomized trial misses strictly defined endpoint, but researchers point to benefit – MedPage Today (free registration required)

 

Commentary on Twitter

 


M-A: Contemporary trends in global mortality of sepsis among young infants less than 90 days.

22 Jun, 2022 | 11:03h | UTC

Contemporary Trends in Global Mortality of Sepsis Among Young Infants Less Than 90 Days: A Systematic Review and Meta-Analysis – Frontiers in Pediatrics

 


RCT: In people with HIV, treating precancerous anal lesions cuts risk of anal cancer by more than half.

21 Jun, 2022 | 11:11h | UTC

News Release: In people with HIV, treating precancerous anal lesions cuts risk of anal cancer by more than half – National Institutes of Health

Original Study: Treatment of Anal High-Grade Squamous Intraepithelial Lesions to Prevent Anal Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

https://twitter.com/NEJM/status/1537185690961686528

 


RCT: Low-dose methylprednisolone does not improve outcomes in critically ill patients with severe community-acquired pneumonia.

21 Jun, 2022 | 11:04h | UTC

Low-dose methylprednisolone treatment in critically ill patients with severe community-acquired pneumonia – Intensive Care Medicine

 


How common is long COVID? Why studies give different answers.

21 Jun, 2022 | 11:03h | UTC

How common is long COVID? Why studies give different answers – Nature

 


M-A: Benefits and risks of rapid initiation of antiretroviral therapy in patients with HIV.

21 Jun, 2022 | 10:41h | UTC

Benefits and Risks of Rapid Initiation of Antiretroviral Therapy: A Systematic Review and Meta-Analysis – Frontiers in Pharmacology

 


M-A: Accuracy of Fluorodeoxyglucose Positron Emission Tomography/ Computerized Tomography for diagnosing periprosthetic joint infections.

21 Jun, 2022 | 10:38h | UTC

A Systematic Review and Meta-Analysis on the Accuracy of Fluorodeoxyglucose Positron Emission Tomography/ Computerized Tomography for Diagnosing Periprosthetic Joint Infections – Frontiers in Surgery

 


Supplement: Digital strategy and social media in infectious diseases.

21 Jun, 2022 | 10:22h | UTC

Homepage: Digital Strategy and Social Media in Infectious Diseases – Clinical Infectious Diseases

Digital Strategy and Social Media for Infectious Diseases

Social Media: Flattening Hierarchies for Women and Black, Indigenous, People Of Color (BIPOC) to Enter the Room Where It Happens

#SoMe the Money! Value, Strategy, and Implementation of Social Media Engagement for Infectious Diseases Trainees, Clinicians, and Divisions

The Digital Classroom: How to Leverage Social Media for Infectious Diseases Education

Educational Impact of #IDJClub, a Twitter-Based Infectious Diseases Journal Club

Surgeons, Infectious Diseases, and Twitter Hit a Home Run for Antibiotic Stewardship

Exploring Coronavirus Disease 2019 Vaccine Hesitancy on Twitter Using Sentiment Analysis and Natural Language Processing Algorithms

Go V.I.R.A.L.: Social Media Engagement Strategies in Infectious Diseases

Creating Effective Infographics and Visual Abstracts to Disseminate Research and Facilitate Medical Education on Social Media

How to Harness the Power of Social Media for Quality Drug Information in Infectious Diseases: Perspectives on Behalf of the Society of Infectious Diseases Pharmacists

Misinformation and Disinformation: The Potential Disadvantages of Social Media in Infectious Disease and How to Combat Them

 


WHO Situation Update: Multi-country monkeypox outbreak.

20 Jun, 2022 | 10:45h | UTC

Multi-country monkeypox outbreak: situation update – World Health Organization

Related:

Monkeypox Genital Lesions – New England Journal of Medicine

Monkeypox: Africa CDC Demands Equal Treatment in Global Allocation of Limited Vaccine Doses – Health Policy Watch

Monkeypox vaccination begins — can the global outbreaks be contained? – Nature

Incubation period for monkeypox: Estimates from the Netherlands.

‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT

Rename monkeypox strains to remove geographic stigma, researchers say – Science

Clinical management and infection prevention and control for monkeypox: Interim rapid response guidance, 10 June 2022 – World Health Organization

2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention

As monkeypox threat grows, scientists debate best vaccine strategy – Science

Monkeypox is a new global threat. African scientists know what the world is up against – Science

WHO Experts Emphasize ‘Window of Opportunity’ to Control Monkeypox Spread as Cases Outside Africa Double Again – Health Policy Watch

Genetic data indicate at least two separate monkeypox outbreaks underway, suggesting wider spread – STAT

Experts highlight sexual aspect of monkeypox spread – CIDRAP

What to Know About Monkeypox – JAMA

Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization

Principles for monkeypox control in the UK: 4 nations consensus statement – UK Health Security Agency

Monkeypox outbreaks: 4 key questions researchers have – Nature

Study reports first use of antivirals in monkeypox patients – Lancet

Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization

Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization

A Novel International Monkeypox Outbreak – Annals of Internal Medicine

EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT

Monkeypox cases increase across Europe, North America – CIDRAP

Multi-country monkeypox outbreak in non-endemic countries – World Health Organization

Monkeypox goes global: why scientists are on alert – Nature

Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT

What is monkeypox? A microbiologist explains what’s known about this smallpox cousin – The Conversation

Monkeypox: Time to worry or one to ignore? – BBC

UK, Spain, Portugal report more monkeypox cases – CIDRAP

U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT

Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization

Monkeypox cases confirmed in England – latest updates – UK Health Security Agency

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch

European outbreak of monkeypox: what you need to know – The Conversation

Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR

Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News

 


RCT: A restrictive intravenous fluid strategy does not improve outcomes in ICU patients with septic shock.

20 Jun, 2022 | 10:51h | UTC

Restriction of Intravenous Fluid in ICU Patients with Septic Shock – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: No Fewer Deaths Seen With Restricted IV Fluid for Septic Shock – HealthDay

Related:

Restrictive versus Liberal Fluid Therapy for Major Abdominal Surgery – New England Journal of Medicine

Effect of Slower vs Faster Intravenous Fluid Bolus Rates on Mortality in Critically Ill Patients: The BaSICS Randomized Clinical Trial – JAMA

Fluid administration and monitoring in ARDS: which management? – Intensive Care Medicine

Perioperative liberal versus restrictive fluid strategies and postoperative outcomes: a systematic review and metanalysis on randomised-controlled trials in major abdominal elective surgery – Critical Care

 

Commentary on Twitter

 


WHO Interim statement on decision-making considerations for the use of variant updated COVID-19 vaccines.

20 Jun, 2022 | 10:42h | UTC

Interim statement on decision-making considerations for the use of variant updated COVID-19 vaccines – World Health Organization

See also: Interim statement on the composition of current COVID-19 vaccines – World Health Organization

 

Commentary on Twitter (thread – click for more)

 


Consensus Study: A core outcome set for post-COVID-19 condition in adults for use in clinical practice and research.

20 Jun, 2022 | 10:31h | UTC

A core outcome set for post-COVID-19 condition in adults for use in clinical practice and research: an international Delphi consensus study – The Lancet Respiratory Medicine

News Release: Key outcomes of Long COVID identified in international consensus study – King’s College London

Invited Commentary: Post-COVID-19 condition in children: a COS is urgently needed – The Lancet Respiratory Medicine

 

Commentary on Twitter

 


Clues to long Covid: Scientists strive to unravel what is driving disabling symptoms.

20 Jun, 2022 | 10:30h | UTC

Clues To Long Covid – Science

 


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