Covid-19

Editorial: It’s time to send children back to school.

28 Sep, 2021 | 09:49h | UTC

It’s time to send children back to school – Nature Medicine

 

---

COVID-19 testing moves out of the clinic and into the home.

28 Sep, 2021 | 09:46h | UTC

COVID-19 Testing Moves Out of the Clinic and Into the Home – JAMA

 

---

Study shows COVID-19 has caused the biggest decrease in life expectancy since World War II.

28 Sep, 2021 | 09:51h | UTC

News release: COVID-19 has caused the biggest decrease in life expectancy since World War II – University of Oxford

Original study: Quantifying impacts of the COVID-19 pandemic through life-expectancy losses: a population-level study of 29 countries – International Journal of Epidemiology

Commentaries:

Life expectancy falls in 27 of 29 nations amid COVID-19 – CIDRAP

Covid has wiped out years of progress on life expectancy, finds study – The Guardian

Related:

Just how do deaths due to COVID-19 stack up?

Tracking excess mortality across countries during the COVID-19 pandemic with the World Mortality Dataset.

Exploring the gap between excess mortality and COVID-19 deaths in 67 countries.

Report: Three new estimates of India’s all-cause excess mortality during the COVID-19 Pandemic – pandemic death toll estimated to be between 3.4 million and 4.9 million excess deaths.

COVID-19 has caused 6.9 million deaths globally, more than double what official reports show

 

Commentary on Twitter

The Covid-19 pandemic has resulted in the largest loss of life expectancy since World War II, worst among American menhttps://t.co/7eNCkwBuJA @jm_aburto @UniofOxford @OxfordDemSci @ridhikash07 @melindacmills pic.twitter.com/ckRIDD9G4m

— Eric Topol (@EricTopol) September 27, 2021

 

---

Evidence shows that, yes, masks prevent COVID-19 – and surgical masks are the way to go.

28 Sep, 2021 | 09:45h | UTC

Evidence shows that, yes, masks prevent COVID-19 – and surgical masks are the way to go – The Conversation

Related: [Preprint] Largest study of masks yet details their importance in fighting Covid-19.

 

---

Functioning of the international health regulations during the COVID-19 pandemic.

28 Sep, 2021 | 09:41h | UTC

Functioning of the International Health Regulations during the COVID-19 pandemic – The Lancet

 

---

Systematic review: Can non-pharmacological measures prevent or reduce Covid-19 (SARS-CoV-2) infections in long term care facilities?

28 Sep, 2021 | 09:47h | UTC

Commentary: Can non-pharmacological measures prevent or reduce Covid-19 (SARS-CoV-2) infections in long term care facilities? – Cochrane Library

Original study: Non‐pharmacological measures implemented in the setting of long‐term care facilities to prevent SARS‐CoV‐2 infections and their consequences: a rapid review – Cochrane Library

 

---

Review: The biological and clinical significance of emerging SARS-CoV-2 variants.

28 Sep, 2021 | 09:43h | UTC

The biological and clinical significance of emerging SARS-CoV-2 variants – Nature Reviews Genetics

 

Commentary on Twitter

A Review in @NatureRevGenet describes the latest understanding of the emergence and properties of SARS-CoV-2 genetic variants, particularly those designated as WHO “variants of concern.” https://t.co/MUERXQRQxd pic.twitter.com/6dsHEMmk2p

— Nature Portfolio (@NaturePortfolio) September 22, 2021

 

---

Updated WHO Living Guideline: Therapeutics and COVID-19.

26 Sep, 2021 | 22:16h | UTC

Therapeutics and COVID-19: living guideline – World Health Organization

WHO Statement: On new recommendation for treatment of COVID-19 patients: WHO calls for equitable access to casirivimab and imdevimab for COVID-19

See also:

WHO recommends antibody treatment for COVID patients at high risk of hospital admission.

Antibody and cellular therapies for treatment of covid-19: a living systematic review and network meta-analysis – The BMJ

Commentary: WHO adds new recommendation for COVID-19 monoclonal antibody combo – CIDRAP

 

---

[Preprint] More data showing longer dosing interval increases immune response after Pfizer-BioNTech’s COVID-19 vaccine.

26 Sep, 2021 | 22:15h | UTC

Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a sixteen-week interval between doses – medRxiv

Commentary: Researchers encourage longer dosing intervals for Pfizer-BioNTech’s COVID-19 vaccine – News Medical

Related:

[Preprint] Covid-19: Longer interval between Covid-19 Pfizer vaccine doses boosts immunity.

[Preprint] Delaying second Pfizer vaccine dose to 12 weeks increases specific antibody response 3.5-fold in people over 80 years of age.

Study Commentary | Single-dose Oxford–AstraZeneca COVID-19 vaccine followed by a 12-week booster

3-month interval between first and second dose of Oxford COVID-19 vaccine results in higher vaccine efficacy than 6-week interval

 

---

In Gratitude for mRNA Vaccines.

26 Sep, 2021 | 22:13h | UTC

In Gratitude for mRNA Vaccines – New England Journal of Medicine

 

---

CDC Report: Schools without mask requirements were more likely to have Covid-19 outbreaks.

26 Sep, 2021 | 22:10h | UTC

Association Between K–12 School Mask Policies and School-Associated COVID-19 Outbreaks — Maricopa and Pima Counties, Arizona, July–August 2021 – CDC Morbidity and Mortality Weekly Report

Commentary: Schools Without Mask Requirements More Likely to See COVID-19 Outbreaks – U.S. News

 

Commentary on Twitter

New @CDCMMWR finds schools in two Arizona counties w/o a mask requirement were 3.5 times more likely to have a #COVID19 outbreak than schools requiring masks from the start of the school year. CDC recommends universal masking for all K–12 schools. More: https://t.co/suuuLNItxJ. pic.twitter.com/zYYqXoLH3j

— CDC (@CDCgov) September 24, 2021

 

---

Graphic Perspective: Mask Wars.

26 Sep, 2021 | 22:12h | UTC

Mask Wars – New England Journal of Medicine

 

---

Opinion | Inappropriate Mixing Clinical and Systemic Thinking: Vaccines in the Young.

26 Sep, 2021 | 22:07h | UTC

Inappropriate Mixing Clinical and Systemic Thinking: Vaccines in the Young – Medium

 

---

Fraudulent ivermectin studies open up new battleground between science and misinformation.

26 Sep, 2021 | 22:08h | UTC

Fraudulent ivermectin studies open up new battleground between science and misinformation – The Guardian

 

---

Covid-19 Vaccines – Billions Committed, Millions Delivered.

26 Sep, 2021 | 22:05h | UTC

Billions Committed, Millions Delivered – Think Global Health

 

Commentary on Twitter

We've combed government websites, official statements, COVAX, and media reports, and have identified 61 countries that have donated 361 million COVID vaccine doses to 148 nations.

Dive into our interactive maps/analysis via @samckiernan and @serena_tohmehttps://t.co/rkrYgvmzBw

— Think Global Health (@ThinkGlobalHlth) September 24, 2021

 

---

[Preprint] PRINCIPLE RCT: Colchicine does not improve time to recovery in outpatients with Covid-19 at higher risk of complications.

24 Sep, 2021 | 10:13h | UTC

Colchicine for COVID-19 in adults in the community (PRINCIPLE): a randomised, controlled, adaptive platform trial – medRxiv

Related: COLCORONA RCT: Colchicine for community-treated patients with COVID-19 – findings suggest it may lower death and hospital admission rates, but further studies are required.

 

Commentary on Twitter

While COLCORONA trial found limited evidence that colchicine may reduce COVID-19 related hospitalisation/death
🆕💥💥@TrialPrinciple preprint
Colchicine did NOT improve time to recovery in people at higher risk of complications w COVID-19 in the communityhttps://t.co/2sUoeD7sGV pic.twitter.com/fi2THbxewW

— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) September 23, 2021

 

---

Just how do deaths due to COVID-19 stack up?

24 Sep, 2021 | 10:07h | UTC

Just How Do Deaths Due to COVID-19 Stack Up? – Think Global Health

 

Commentary on Twitter

How do deaths due to COVID-19 compare? Despite a likely undercount in many places, COVID is the leading killer in most of Latin America & Western Europe, says Chris Troeger @IHME_UW. Our interactive map ranks #COVID deaths among all causes since Jan 2020.https://t.co/U8J1uWUsgK

— Think Global Health (@ThinkGlobalHlth) September 23, 2021

 

---

How patient data underpin COVID-19 research – “Tracking the coronavirus SARS-CoV-2, developing treatments and testing vaccines have relied on access to the health data of millions of people. This massive trove could be used to understand other diseases, but not everyone is convinced”.

24 Sep, 2021 | 10:03h | UTC

How patient data underpin COVID-19 research – Nature

 

---

No, vaccinated people are not ‘just as likely’ to spread the Coronavirus as unvaccinated people.

24 Sep, 2021 | 10:06h | UTC

No, Vaccinated People Are Not ‘Just as Likely’ to Spread the Coronavirus as Unvaccinated People – The Atlantic

 

Commentary on Twitter

“Vaccinated people are just as likely to spread the coronavirus.”

This isn't true. But some people — even some very smart people — mistakenly believe this.

Dr. @Craig_A_Spencer explains here why, in this really good piece from @TheAtlantic.https://t.co/9D1dngt3oG

— Paul Sax (@PaulSaxMD) September 23, 2021

 

---

WHO recommends antibody treatment for COVID patients at high risk of hospital admission.

24 Sep, 2021 | 10:11h | UTC

WHO recommends antibody treatment for COVID patients at high risk of hospital admission – British Medical Journal

Original article and infographic: A living WHO guideline on drugs for covid-19 – The BMJ

 

---

COVID-19 vaccines: Keeping pace with SARS-CoV-2 variants.

24 Sep, 2021 | 10:02h | UTC

COVID-19 vaccines: Keeping pace with SARS-CoV-2 variants – Cell

 

Commentary on Twitter

https://twitter.com/Sri_Baqri/status/1438865999281983490

 

---

Review | Interplay between endocrinology, metabolism, and COVID-19 infection.

24 Sep, 2021 | 10:00h | UTC

Interplay between endocrinology, metabolism, and COVID-19 infection – Clinical Medicine Journal

 

---

[Preprint] Third dose of Sinopharm inactivated SARS-CoV-2 vaccine induces robust B and T cell responses.

23 Sep, 2021 | 10:18h | UTC

Robust induction of B cell and T cell responses by a third dose of inactivated SARS-CoV-2 vaccine – medRxiv

Commentaries:

Three doses of inactivated BBIBP-CorV SARS-CoV-2 vaccine induce robust B and T cell responses – News Medical

Sinopharm’s COVID booster reverses antibody decline, enhances cell-based responses – study – Reuters

 

---

Randomized phase 1/2 trial: Safety and immunogenicity of an inactivated COVID-19 vaccine, BBIBP-CorV, in children and adolescents aged 3–17 years.

23 Sep, 2021 | 10:16h | UTC

Safety and immunogenicity of an inactivated COVID-19 vaccine, BBIBP-CorV, in people younger than 18 years: a randomised, double-blind, controlled, phase 1/2 trial – The Lancet Infectious Diseases

Related: Phase 1/2 RCT: CoronaVac is well tolerated and safe and induces strong humoral responses in children and adolescents aged 3–17 years.

 

---

‘Not a zero-sum game’: Sharing vaccines is in countries’ best interests.

23 Sep, 2021 | 10:09h | UTC

‘Not a zero-sum game’: Sharing vaccines is in countries’ best interests – YaleNews

Original article: National interest may require distributing COVID-19 vaccines to other countries – Scientific Reports

 

Commentary on Twitter

"when US has reached the threshold for domestic herd immunity, it would be optimal to donate doses to other countries, as this would allow for a sharp reduction in the inflow of infected individuals from abroad"
– Modeling by @SaadOmer3, @amynmalik & co https://t.co/NFfp39tde6

— Mushfiq Mobarak (@mushfiq_econ) September 16, 2021

 

---