Antibiotic Stewardship
WHO Report signals increasing resistance to antibiotics in bacterial infections in humans.
12 Dec, 2022 | 12:52h | UTCCommentary: WHO report shows rising antibiotic resistance, need for better data – CIDRAP
Commentary on Twitter (thread – click for more)
New WHO report on #AntimicrobialResistance reveals very high levels of resistance in common bacteria frequently causing bloodstream infections in hospitals.
Infection prevention & control is critical to stop the spread and save lives.
More: https://t.co/8dGqw5KgZT pic.twitter.com/XGC2I7KbwB
— World Health Organization (WHO) (@WHO) December 9, 2022
Approach to fever in patients with neutropenia: a review of diagnosis and management.
8 Dec, 2022 | 12:44h | UTCRelated:
Podcast | Procalcitonin revisited.
7 Dec, 2022 | 14:17h | UTCAnnals On Call – Procalcitonin Revisited – Annals of Internal Medicine
RCT | Efficacy of postoperative oral cephalexin and metronidazole on SSI in obese women undergoing cesarean section.
7 Dec, 2022 | 14:13h | UTC
Redefining Staphylococcus aureus bacteremia: a structured approach guiding diagnostic and therapeutic management.
5 Dec, 2022 | 00:20h | UTC
Commentary on Twitter
?️⚡️⚡️ @VanceFowler5
Redefining Staphylococcus aureus bacteremia: a structured approach guiding diagnostic and therapeutic management
cc @JonathanRyderMD @BrentFooter @syctong #IDTwitterhttps://t.co/VGTHKT5fNA pic.twitter.com/u6tl7NcJS3— Antibiotic Steward Bassam Ghanem?? (@ABsteward) November 9, 2022
Under a Creative Commons Attribution (CC BY 4.0) license
Perspective | Push to use antibiotics to prevent sexually transmitted infections raises concerns.
2 Dec, 2022 | 14:27h | UTCPush to use antibiotics to prevent sexually transmitted infections raises concerns – Nature
German guideline on diverticular disease/diverticulitis.
30 Nov, 2022 | 13:41h | UTCEditorial: New German guidelines for the management of diverticulitis – UEG Journal
Related:
Systematic Review: Antibiotics for uncomplicated diverticulitis.
Efficacy and Safety of Non-Antibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-Label, Non-Inferiority Trial – Annals of Surgery (link to abstract – $ for full-text)
Elective surgical management of diverticulitis – Current Problems in Surgery
Management of Colonic Diverticulitis – Agency for Healthcare Research and Quality
Liposomal amphotericin B — Past, present and future.
29 Nov, 2022 | 14:03h | UTCLiposomal amphotericin B—the past – Journal of Antimicrobial Chemotherapy
Liposomal amphotericin B—the present – Journal of Antimicrobial Chemotherapy
Liposomal amphotericin B—the future – Journal of Antimicrobial Chemotherapy
RCT | Rezafungin vs. caspofungin for treatment of candidaemia and invasive candidiasis.
29 Nov, 2022 | 13:54h | UTCRezafungin versus caspofungin for treatment of candidaemia and invasive candidiasis (ReSTORE): a multicentre, double-blind, double-dummy, randomised phase 3 trial – The Lancet (link to abstract – $ for full-text)
Review | Infectious complications of abortion.
29 Nov, 2022 | 13:56h | UTCInfectious Complications of Abortion – Open Forum Infectious Diseases
Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019.
27 Nov, 2022 | 22:30h | UTCCommentary: Report highlights the deadly impact of bacterial infections – CIDRAP
Commentary on Twitter (thread – click for more)
1 in 8 deaths are due to the deadliest bacterial pathogens in the world, making them the second-leading cause of death behind ischemic heart disease @TheLancethttps://t.co/PEPYvxRcqV pic.twitter.com/S6odJodsVj
— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) November 21, 2022
RCT | Rectal culture-based vs. empirical antibiotic prophylaxis to prevent infections in men undergoing transrectal prostate biopsy.
27 Nov, 2022 | 22:28h | UTCRectal culture-based versus empirical antibiotic prophylaxis to prevent infectious complications in men undergoing transrectal prostate biopsy: a randomized, non-blinded multicenter trial – Clinical Infectious Diseases (link to abstract – $ for full-text)
Commentary on Twitter
RCT of rectal culture-based vs. empiric antibiotic prophylaxis to prevent infectious complications after transrectal prostate biopsy.
Potentially practice-changing study. Thoughts, @AshleyGWinter? @sigal_md Others? https://t.co/rJQusECapO @CIDJournal pic.twitter.com/94tBa2i1eN
— Paul Sax (@PaulSaxMD) November 24, 2022
RCT | Treatment of early Lyme Disease with doxycycline for 7 days is noninferior to treatment for 14 days.
23 Nov, 2022 | 14:06h | UTCTreatment of erythema migrans with doxycycline for 7 days versus 14 days in Slovenia: a randomised open-label non-inferiority trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Commentary: Shorter Duration of Antibiotics Noninferior for Lyme Disease – JAMA (free for a limited period)
Commentary on Twitter
New research: Treatment of erythema migrans with doxycycline for 7 days versus 14 days in Slovenia: a randomised open-label non-inferiority trialhttps://t.co/8lktc4gxzG pic.twitter.com/mP2e0Kn7C5
— The Lancet Infectious Diseases (@TheLancetInfDis) October 7, 2022
Epidemiology of ICU-onset bloodstream infection: prevalence, pathogens, and risk factors among 150,948 ICU patients.
21 Nov, 2022 | 14:14h | UTC
ISPD peritonitis guideline recommendations: 2022 update on prevention and treatment.
18 Nov, 2022 | 13:23h | UTC
M-A | Efficacy and safety of treatments for different stages of syphilis.
18 Nov, 2022 | 13:20h | UTC
M-A | A short course of antibiotics is noninferior to long-course therapy in children with nonsevere pneumonia.
16 Nov, 2022 | 13:43h | UTCShort-Course vs Long-Course Antibiotic Therapy for Children With Nonsevere Community-Acquired Pneumonia: A Systematic Review and Meta-analysis – JAMA Pediatrics (free for a limited period)
Commentary: Review: Shorter antibiotic course sufficient for kids with pneumonia – CIDRAP
Related:
ACP Guidance: Appropriate Use of Short-Course Antibiotics in Common Infections
RCT: 7 days of antibiotic therapy as good as 14 days for afebrile men with urinary tract infection.
Meta-Analysis: Efficacy of Short-Course Antibiotic Treatments for Community-Acquired Pneumonia
SR | Biomarkers as point‐of‐care tests to guide use of antibiotics in people with acute respiratory infections in primary care.
11 Nov, 2022 | 13:47h | UTC
RCT | No benefit from a model-informed precision dosing of beta-lactam antibiotics and ciprofloxacin in critically ill patients.
11 Nov, 2022 | 13:46h | UTC
Commentary on Twitter
Individualising beta-lactam ABTs/ciprofoxacin therapy in #ICU using model-informed precision dosing vs standard dosing, multicentre ?? RCT
No evidence for clinical effect of MIPD on LOS or other secondary outcomes in critically ill pts#FOAMcc @yourICM
?️https://t.co/6HzLBBnFdU pic.twitter.com/uErsHNAV5p— Intensive Care Medicine (@yourICM) November 9, 2022
Editorial | The urgent need to recognize and properly address prenatal-onset group B Streptococcus disease.
10 Nov, 2022 | 13:59h | UTC
Guideline | Antibiotic prophylaxis for tube thoracostomy placement in trauma.
8 Nov, 2022 | 12:19h | UTC
Guidelines for empirical antibacterial therapy of sepsis in adults.
7 Nov, 2022 | 12:40h | UTC
Review | Early appropriate diagnostics and treatment of MDR Gram-negative infections.
7 Nov, 2022 | 12:19h | UTCRelated:
Commentary on Twitter
This is a ⚡fantastic article⚡
by super ?s Dr. Bassetti & @davidvanduin @jac_amr
We really need more adoption to RDTs coupled with stewardship programs
Early appropriate diagnostics and treatment of MDR Gram-negative infections #IDTwitter #MedEd https://t.co/h6eOvK2iH8 pic.twitter.com/WBjogJ6IYu— Antibiotic Steward Bassam Ghanem?? (@ABsteward) September 14, 2022
Under a https://creativecommons.org/licenses/by/4.0/ license
Review | The threat of multidrug-resistant/extensively drug-resistant Gram-negative respiratory infections.
7 Nov, 2022 | 12:17h | UTCRelated:
Review | How and when to manage respiratory infections out of hospital.
7 Nov, 2022 | 12:15h | UTCHow and when to manage respiratory infections out of hospital – European Respiratory Review