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Antibiotic Stewardship

Syphilis in dermatology: recognition and management

31 Jan, 2023 | 14:01h | UTC

Syphilis in Dermatology: Recognition and Management – American Journal of Clinical Dermatology (if the link is paywalled, try this one in PMC)

 


Cohort Study | Severe lymphopenia may predict worse outcomes in hospitalized patients with pneumococcal CAP

31 Jan, 2023 | 13:52h | UTC

Impact of severe lymphopenia on the early prediction of clinical outcome in hospitalized patients with pneumococcal community-acquired pneumonia – Infection (if the link is paywalled, try this one in PMC)

 


Review | Skin infections due to Panton-Valentine Leukocidin–producing S. aureus

31 Jan, 2023 | 13:44h | UTC

Skin Infections Due to Panton-Valentine Leukocidin–Producing S. Aureus – Deutsches Ärzteblatt international

 


M-A | Vancomycin area under the curve vs. trough only guided dosing and the risk of acute kidney injury

31 Jan, 2023 | 13:32h | UTC

Vancomycin area under the curve versus trough only guided dosing and the risk of acute kidney injury: Systematic review and meta-analysis – Pharmacology

 


Review | The blood–brain barrier and optimization of antibiotics for the treatment of CNS infections in adults

27 Jan, 2023 | 11:55h | UTC

The Blood–Brain Barrier and Pharmacokinetic/Pharmacodynamic Optimization of Antibiotics for the Treatment of Central Nervous System Infections in Adults – Antibiotics

 


RCT | 2 days of postoperative antibiotics is noninferior to 5 days in patients with complex appendicitis

24 Jan, 2023 | 14:33h | UTC

2 days versus 5 days of postoperative antibiotics for complex appendicitis: a pragmatic, open-label, multicentre, non-inferiority randomised trial – The Lancet (link to abstract – $ for full-text)

Commentary: Trial supports shorter postoperative antibiotics for complex appendicitis – CIDRAP

 

Commentary on Twitter

 


ASCO Guideline | Management of fever and neutropenia in pediatric patients with cancer and hematopoietic cell transplantation recipients

24 Jan, 2023 | 14:28h | UTC

Guideline for the Management of Fever and Neutropenia in Pediatric Patients With Cancer and Hematopoietic Cell Transplantation Recipients: 2023 Update – Journal of Clinical Oncology

 


Recommendations for the diagnosis and management of COVID-19 associated bacterial and fungal infections

20 Jan, 2023 | 14:48h | UTC

Recommendations and guidelines for the diagnosis and management of Coronavirus Disease-19 (COVID-19) associated bacterial and fungal infections in Taiwan – Journal of Microbiology, Immunology and Infection

 


RCT | Aqueous povidone-iodine vs. normal saline for intraoperative wound irrigation on the incidence of SSI after GI surgery

19 Jan, 2023 | 13:54h | UTC

Aqueous Povidone-Iodine Versus Normal Saline For Intraoperative Wound Irrigation On The Incidence Of Surgical Site Infection In Clean-Contaminated Wounds After Gastroenterological Surgery: A Single Institute, Prospective, Blinded-Endpoint, Randomized Controlled Trial – Annals of Surgery (link to abstract – $ for full-text)

 


Review | Surgical site infection prevention

18 Jan, 2023 | 14:31h | UTC

Surgical Site Infection Prevention: A Review – JAMA (free for a limited period)

Author interview: Surgical Site Infection Prevention – JAMA

Related:

Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 – JAMA Surgery 

Global guidelines on the prevention of surgical site infection – World Health Organization 

Surgical site infections: prevention and treatment – National Institute for Health and Care Excellence 

APSIC guidelines for the prevention of surgical site infections – Antimicrobial Resistance & Infection Control

Perioperative care bundles for the prevention of surgical-site infections: meta-analysis – British Journal of Surgery

AAOS Guideline: Prevention of surgical site infections after major extremity trauma.

 


Consensus statement | Use of a 4-month treatment regimen for drug susceptible TB in children with uncomplicated disease

18 Jan, 2023 | 14:25h | UTC

Consensus statement on the use of a four-month treatment regimen for drug susceptible tuberculosis in children (< 10 years of age) with uncomplicated disease – Australian Government Department of Health and Aged Care

 


SR | Pre‐emptive antifungal therapy vs. empirical antifungal therapy for febrile neutropenia in people with cancer

18 Jan, 2023 | 14:18h | UTC

Pre‐emptive antifungal therapy versus empirical antifungal therapy for febrile neutropenia in people with cancer – Cochrane Library

Summary: Pre-emptive versus empirical antifungal therapy in people with cancer who have febrile neutropenia – Cochrane Library

 


SHEA statement on antibiotic stewardship in hospitals during public health emergencies

17 Jan, 2023 | 13:18h | UTC

SHEA statement on antibiotic stewardship in hospitals during public health emergencies – Infection Control & Hospital Epidemiology 

 


Review | Viral infections in critical care

17 Jan, 2023 | 13:01h | UTC

Viral infections in critical care: a narrative review – Anaesthesia

 


M-A | Colonisation with ESCR-Enterobacterales and infection risk in surgical patients

17 Jan, 2023 | 12:58h | UTC

Colonisation with Extended-Spectrum Cephalosporin-Resistant Enterobacterales and Infection Risk in Surgical Patients: A Systematic Review and Meta-analysis – Infectious Diseases and Therapy

 


Best infectious diseases articles from 2022 – A year end review of non-COVID literature

15 Jan, 2023 | 20:31h | UTC

Best Infectious Diseases Articles From 2022 – A Year End Review Of Non-COVID Literature – IDstewardship

 

Commentary on Twitter

 


RCT | Colistin monotherapy vs. combination therapy for carbapenem-resistant organisms

13 Jan, 2023 | 13:36h | UTC

Colistin Monotherapy versus Combination Therapy for Carbapenem-Resistant Organisms – NEJM Evidence

Commentary: Colistin Alone or with Meropenem: Is More Better? – NEJM Journal Watch

Related: Colistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria: an open-label, randomised controlled trial – The Lancet

 


Study suggests delivering high concentrations of antibiotics into the implantation site is feasible for infections in implanted CV electronic devices

13 Jan, 2023 | 13:26h | UTC

Regional Antibiotic Delivery for Implanted Cardiovascular Electronic Device Infections – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: 

Direct Delivery of Antibiotics to CV Device Pocket Infections Appears Promising – TCTMD

Regional Antibiotics for Implanted Cardiovascular Electronic Device Infections – American College of Cardiology

 


Cohort Study | Antibiotic exposure linked to increased risk of inflammatory bowel disease

13 Jan, 2023 | 13:25h | UTC

Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study – Gut

News Release: Frequent use of antibiotics may heighten inflammatory bowel disease risk in over 40s – BMJ Newsroom

Commentaries: 

Antibiotics may increase risk of inflammatory bowel disease, study finds – CIDRAP

Antibiotic Exposure Positively Linked to IBD Development – HealthDay

 

Commentary on Twitter

 


RCT | Second-line levofloxacin-based quadruple therapy vs. bismuth-based quadruple therapy for Helicobacter pylori eradication

12 Jan, 2023 | 13:06h | UTC

Second-line levofloxacin-based quadruple therapy versus bismuth-based quadruple therapy for Helicobacter pylori eradication and long-term changes to the gut microbiota and antibiotic resistome: a multicentre, open-label, randomised controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


SR | Interventions for the eradication of methicillin‐resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis

12 Jan, 2023 | 13:04h | UTC

Interventions for the eradication of meticillin‐resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis – Cochrane Library

 


Review | Early diagnosis and prevention of infections in cirrhosis

12 Jan, 2023 | 12:47h | UTC

Early Diagnosis and Prevention of Infections in Cirrhosis – Seminars in Liver Disease

 


RCT | Efficacy and safety of azithromycin vs. placebo to treat lower respiratory tract infections associated with low procalcitonin.

16 Dec, 2022 | 13:30h | UTC

Efficacy and safety of azithromycin versus placebo to treat lower respiratory tract infections associated with low procalcitonin: a randomised, placebo-controlled, double-blind, non-inferiority trial – The Lancet Infectious Diseases (link to abstract – $ for full-text) 

Commentary: Study Evaluates Biomarker to Help Curb Unnecessary Antibiotic Use: Placebo Worse Than Antibiotics After 5 Days, But Similar at Day 11 – Duke Health

 

Commentary on Twitter

 


SR | Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.

14 Dec, 2022 | 14:51h | UTC

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins – Cochrane Library

 


Prevention of device-related infections in patients with cancer: Current practice and future horizons.

13 Dec, 2022 | 14:30h | UTC

Prevention of device-related infections in patients with cancer: Current practice and future horizons – CA: A Cancer Journal for Clinicians

 


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