RCT | 2 days of postoperative antibiotics is noninferior to 5 days in patients with complex appendicitis

2 days versus 5 days of postoperative antibiotics for complex appendicitis: a pragmatic, open-label, multicentre, non-inferiority randomised trial – The Lancet (link to abstract – $ for full-text)

Commentary: Trial supports shorter postoperative antibiotics for complex appendicitis – CIDRAP

Commentary on Twitter

After laparoscopic appendicectomy for complex appendicitis, 2 days versus 5 days of intravenous #antibiotics was non-inferior in terms of infectious complications and mortality within 90 days, suggests new Dutch study: https://t.co/oRsf8BQgAd

— The Lancet (@TheLancet) January 19, 2023