Hematology (all articles)
Randomized Controled Trial: Genotype-Guided Warfarin Dosing on Clinical Events and Anticoagulation Control
27 Sep, 2017 | 14:02h | UTCEffect of Genotype-Guided Warfarin Dosing on Clinical Events and Anticoagulation Control Among Patients Undergoing Hip or Knee Arthroplasty: The GIFT Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Genotyping Reduces Adverse Events with Warfarin – Cardiobrief (free) AND Genotype-Guided Warfarin Dosing Reduces Adverse Events After Hip, Knee Arthroplasty – Physician’s First Watch (free)
Review: Sickle Cell Disease
24 Sep, 2017 | 00:15h | UTCSickle Cell Disease – Gene Reviews (free)
Review: Evaluation of bleeding in patients receiving direct oral anticoagulants
20 Sep, 2017 | 21:11h | UTC
Review: Multiple Myeloma Emergencies
20 Sep, 2017 | 21:06h | UTCMultiple Myeloma Emergencies – emDocs (free)
Systematic Review: Optimisation of chemotherapy and radiotherapy for Hodgkin lymphoma patients
20 Sep, 2017 | 20:37h | UTCOriginal article: Optimisation of chemotherapy and radiotherapy for untreated Hodgkin lymphoma patients with respect to second malignant neoplasms, overall and progression-free survival: individual participant data analysis – Cochrane Library (link to abstract – $ for full-text)
Study: Blood Management Program Reduces Unnecessary Transfusions and Costs
18 Sep, 2017 | 14:54h | UTCImplementing a Health System–wide Patient Blood Management Program with a Clinical Community Approach – Anesthesiology (link to abstract – $ for full-text)
Commentary: Johns Hopkins Health System Reduces Unnecessary Transfusions With New Blood Management Program (free)
Related: High value quality improvement – High Value Practice Academic Alliance (free)
Review: Poems Syndrome
18 Sep, 2017 | 13:49h | UTCPoems Syndrome: an Update – Mediterranean Journal of Hematology and Infectious Diseases (free)
Guideline: Evaluation of the Neck Mass in Adults
12 Sep, 2017 | 21:09h | UTCSee also: Executive Summary (free) AND News Release (free)
Commentaries: Neck Mass in Adults: Guideline for Evaluation Provides Framework for Timely Diagnosis – NewsWise (free) AND Guidelines Issued on Evaluating Neck Masses – Physician’s First Watch (free)
Guideline: Iodine-based contrast media, multiple myeloma and monoclonal gammopathies
12 Sep, 2017 | 20:45h | UTC
Review: Multiple Myeloma Emergencies
9 Sep, 2017 | 22:43h | UTCMultiple Myeloma Emergencies – emDocs (free)
Meta-analysis: FDG PET/CT in Patients with Suspected Paraneoplastic Syndrome
9 Sep, 2017 | 14:34h | UTCCommentary: FDG PET/CT Helps Identify Malignancy Source in Paraneoplastic Syndrome – Medscape (free registration required)
Review: Anticoagulation Bridge Therapy in Patients with Atrial Fibrillation
7 Sep, 2017 | 22:03h | UTCSource: Hospital Medicine Virtual Journal Club (free)
Guideline: Diagnosis and empirical treatment of fever of unknown origin (FUO) in adult neutropenic patients
6 Sep, 2017 | 18:36h | UTCRelated Guidelines: Management of febrile neutropaenia: ESMO Clinical Practice Guidelines (free) AND Guideline for the Management of Fever and Neutropenia in Children With Cancer and Hematopoietic Stem-Cell Transplantation Recipients: 2017 Update (free)
Study: Effect of Palliative Care on Aggressiveness of End-of-Life Care Among Patients With Advanced Cancer
4 Sep, 2017 | 15:45h | UTCEffect of Palliative Care on Aggressiveness of End-of-Life Care Among Patients With Advanced Cancer – Journal of Oncology Practice (link to abstract – $ for full-text)
Commentaries: Palliative Care May Substantially Decrease Health-Care Utilization in Patients With Advanced Cancer – ASCO Post (free) AND End-of-Life Palliative Care Lowered Utilization for Patients With Cancer – AJMC (free) AND Palliative Care Cut Healthcare Use in Advanced Cancer – MedPage Today (free registration required)
Related guideline: Integration of Palliative Care Into Standard Oncology Care: American Society of Clinical Oncology Clinical Practice Guideline Update (free)
Study: Intra-articular versus Intravenous Application of Tranexamic Acid in Total Knee Arthroplasty
4 Sep, 2017 | 13:48h | UTCIntra-articular Application is More Effective Than Intravenous Application of Tranexamic Acid in Total Knee Arthroplasty: A Prospective Randomized Controlled Trial – Journal of Arthroplasty (link to abstract – $ for full-text)
Source: EvidenceAlerts
Guideline: Indication and Timing of Hematopoietic Cell Transplantation in Mature T-Cell and NK/T-Cell Lymphomas
4 Sep, 2017 | 13:57h | UTCClinical Practice Recommendations on Indication and Timing of Hematopoietic Cell Transplantation in Mature T-Cell and NK/T-Cell Lymphomas: an International Collaborative Effort on Behalf of the Guidelines Committee of the American Society for Blood and Marrow Transplantation (link to abstract – $ for full-text)
Commentary and Summary: Guideline on HCT for Certain Lymphoma Types – Hematology News (free registration required)
FDA approval brings first gene therapy to the United States
3 Sep, 2017 | 21:19h | UTCFDA News Release: FDA approval brings first gene therapy to the United States (free)
Commentaries: A $475,000 cancer drug: Wall Street sees ‘bargain’; patients see ‘completely broken’ system – HealthNewsReview (free) FDA Approves First CAR-T Cell Therapy for Pediatric Acute Lymphoblastic Leukemia – National Institutes of Health (free) AND FDA Approves First Gene-Altering Leukemia Treatment, Costing $475.000 – New York Times (10 articles per month are free) AND The FDA Approves a Landmark Cancer Drug – The Atlantic (free)
“…is a cancer therapy that represents several things at once: a game-changing way to treat cancer through genetic engineering, a novel paradigm for the biotech business, and the latest turn in the debate over just how astronomically expensive a life-saving therapy can be”. (from The Atlantic)
Review: New-onset acute thrombocytopenia in hospitalized patients
1 Sep, 2017 | 20:40h | UTCSource: Critical Care Reviews Newsletter
Guidelines for the management of acute joint bleeds and chronic synovitis in haemophilia
30 Aug, 2017 | 18:10h | UTCSource: Medscape New Guidelines and Recommendations (free registration required)
Systematic Review: Deferasirox for managing iron overload in people with thalassaemia
29 Aug, 2017 | 14:56h | UTCDeferasirox for managing iron overload in people with thalassaemia – Cochrane Library (free)
Full review: Deferasirox for managing iron overload in people with thalassaemia – Cochrane Library (link to abstract – $ for full-text)
Iron chelation with oral Deferasirox (instead of injected deferoxamine) may offer an important treatment option for people with thalassaemia and secondary iron overload.
Review: Light-chain cardiac amyloidosis
26 Aug, 2017 | 16:08h | UTCLight-chain cardiac amyloidosis: strategies to promote early diagnosis and cardiac response – Heart (free)
Review: Advances in the treatment of relapsed/refractory chronic lymphocytic leukemia
26 Aug, 2017 | 15:36h | UTCAdvances in the treatment of relapsed/refractory chronic lymphocytic leukemia – Annals of Hematology (free)
Review: Oral health of adult patients undergoing hematopoietic cell transplantation
26 Aug, 2017 | 15:35h | UTC
Systematic Review and Meta-analysis: Screening for Occult Cancer in Patients With Unprovoked Venous Thromboembolism
24 Aug, 2017 | 20:41h | UTCScreening for Occult Cancer in Patients With Unprovoked Venous Thromboembolism: A Systematic Review and Meta-analysis of Individual Patient Data – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Outcomes of limited cancer screening after unprovoked VTE similar to extensive screening – ACP Hospitalist (free) AND Cancer Screening Not Recommended in Patients With VTEs – Medscape (free registration required) AND Extensive cancer screening may not improve outcomes for patients with unprovoked venous thromboembolism – 2 Minute Medicine (free) AND Screening for Occult Cancer in Patients With Unprovoked Venous Thromboembolism – ASCO Post (free)
Guideline: Newly diagnosed and relapsed mantle cell lymphoma
22 Aug, 2017 | 19:16h | UTC