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Hematology (all articles)

Management of Inherited Bleeding Disorders in Pregnancy

1 May, 2017 | 16:47h | UTC

Management of Inherited Bleeding Disorders in Pregnancy: Green-top Guideline – Royal College of Obstetricians and Gynaecologists (free)

 


Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage

27 Apr, 2017 | 16:33h | UTC

Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial – The Lancet (free)

Editorial: WOMAN: reducing maternal deaths with tranexamic acid (free)

Commentary: Overlooked Drug Could Save Thousands Of Moms After Childbirth – NPR Goats and Soda (free)

“Tranexamic acid reduced deaths of mothers caused by bleeding after childbirth by 1/3” (RT @LSHTMpress see Tweet)

 


Standardized Criteria for Palliative Care Consultation

24 Apr, 2017 | 15:25h | UTC

Prospective, before-after cohort study: Standardized Criteria for Palliative Care Consultation on a Solid Tumor Oncology Service Reduces Downstream Health Care Use – Journal of Oncology Practice (free)

Editorial: Making the Right Thing Easier to Do: Standardized Integration of Oncology and Palliative Care – Journal of Oncology Practice (free)

Related Guideline: Integration of Palliative Care Into Standard Oncology Care: American Society of Clinical Oncology Clinical Practice Guideline Update (free)

Commentaries on the study: Standardized Palliative Care Consults Cut Cancer Readmissions – Also, less chemotherapy after discharge – MedPage Today (free registration required) AND Standardized Cancer Palliative Care Consults Linked to Stronger Home-Based Support – AJMC (free)

Patients with at least one of the following 4 criteria: 1) advanced solid tumor; 2) prior hospitalization within 30 days; 3) hospitalization > 7 days; or 4) active symptoms – received automatic palliative care consultation. The rates of 30-day readmissions dropped from 35% to 18% and chemotherapy after discharge dropped from 44% to 18%.

 


New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management

18 Apr, 2017 | 14:05h | UTC

New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)

Source: Critical Care Reviews Newsletter

 


European Association of Urology releases its 1st thromboprophylaxis guideline

14 Apr, 2017 | 16:10h | UTC

European Association of Urology releases its 1st thromboprophylaxis guideline (free)

 

Procedure-specific Risks of Thrombosis and Bleeding in Urological Cancer Surgery: Systematic Review and Meta-analysis – European Urology (free)

“Extended thromboprophylaxis is warranted in some procedures (eg, open and robotic cystectomy) but not others (eg, robotic prostatectomy without pelvic lymph node dissection in low-risk patients)

 

Procedure-specific Risks of Thrombosis and Bleeding in Urological Non-cancer Surgery: Systematic Review and Meta-analysis – European Urology (free)

“Extended prophylaxis is warranted for some procedures (eg, kidney transplantation procedures in high-risk patients) but not others (transurethral resection of the prostate and reconstructive female pelvic surgery in low-risk patients)”

 


Emergencies in Hematology and Oncology

11 Apr, 2017 | 15:45h | UTC

Emergencies in Hematology and Oncology – Mayo Clinic Proceedings (free)

Comprehensive review covering the most common oncological emergencies.

 


Cancer patients have 55% greater risk of suicide

6 Apr, 2017 | 15:05h | UTC

Cancer patients have 55% greater risk of suicide, study finds – The Guardian (free) (RT @ghn_news)

 


American College of Radiology (ACR) Appropriateness Criteria Adds Topics

4 Apr, 2017 | 21:19h | UTC

ACR Appropriateness Criteria Adds Topics, Covers More Clinical Variants Than Ever Before (free)

Browse Appropriateness Criteria Topics (free)

Source: Newswise

This comprehensive guide from American College of Radiology (ACR) covers 230 topics with more than 1,100 clinical indications and has just been updated. It is a very useful resource for doctors in all specialties to guide which exam is most appropriate in each clinical situation.

 


Eosinophilia in Primary Care

4 Apr, 2017 | 19:30h | UTC

Eosinophilia – Primary Care: Clinics in Office Practice (free)

 


Anemia and blood transfusion in the critically ill patient with cardiovascular disease

3 Apr, 2017 | 19:14h | UTC

Anemia and blood transfusion in the critically ill patient with cardiovascular disease – Critical Care (free)

 


Non–Vitamin K Antagonist Oral Anticoagulants in Patients With Atrial Fibrillation and Valvular Heart Disease

30 Mar, 2017 | 17:27h | UTC

Non–Vitamin K Antagonist Oral Anticoagulants in Patients With Atrial Fibrillation and Valvular Heart Disease – Journal of the American College of Cardiology (free)

Source: SciCombinator

Except for patients with moderate/severe mitral stenosis or mechanical heart valves, who were excluded in most trials, high-dose NOACs was as effective and safe for patients with valvular heart disease as for patients without valvular disorders.

 


HERDOO2 rule to guide treatment duration for women with unprovoked venous thrombosis

29 Mar, 2017 | 17:07h | UTC

Validating the HERDOO2 rule to guide treatment duration for women with unprovoked venous thrombosis: multinational prospective cohort management study – The BMJ (free)

Source: Richard Lehman’s weekly review

HERDOO2 rule stands for Hyperpigmentation, Edema, or Redness in either leg; D-dimer level ≥250 μg/L; Obesity with body mass index ≥30; or Older age, ≥65 years. The authors concluded that women with a first unprovoked VTE event and none or one of the HERDOO2 criteria have a low risk (3.0% per patient year) of recurrent VTE and can safely discontinue anticoagulants after completing short term treatment.

 


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