Hematology (all articles)
Review: Diagnosis and classification of hematologic malignancies on the basis of genetics
7 Oct, 2017 | 21:52h | UTCDiagnosis and classification of hematologic malignancies on the basis of genetics – Blood (free)
Research: Efficiency and safety of varying the frequency of whole blood donation
3 Oct, 2017 | 21:57h | UTCCommentaries: The price of blood is measured in iron – The Lancet (free) AND Increasing frequency of blood donation has no major side effects – ScienceDaily (free)
Research: D-dimer to guide the intensity of anticoagulation after mechanical heart valve replacement
1 Oct, 2017 | 16:24h | UTCD-dimer to guide the intensity of anticoagulation in Chinese patients after mechanical heart valve replacement: a randomized controlled trial – Journal of Thrombosis and Haemostasis (link to abstract – $ for full-text)
Source: ACP Journal Wise ($)
Research: Prevalence of Anemia 10 Years After Roux-en-Y Gastric Bypass
1 Oct, 2017 | 16:18h | UTCPrevalence of Anemia 10 Years After Roux-en-Y Gastric Bypass in a Single Veterans Affairs Medical Center – JAMA Surgery (link to abstract – $ for full-text)
Commentary: Long-Term Follow-up after Weight-Loss Surgery Finds High Rate of Anemia – The JAMA Network (free)
Research: Association of Guideline-Adherent Antibiotic Treatment With Readmission of Children With Acute Chest Syndrome
1 Oct, 2017 | 14:53h | UTCAssociation of Guideline-Adherent Antibiotic Treatment With Readmission of Children With Sickle Cell Disease Hospitalized With Acute Chest Syndrome – JAMA Pediatrics (link to abstract – $ for full-text)
Commentaries: Acute Chest Syndrome in Pediatric Sickle-cell Disease: Antibiotic Guidelines Matter – Medscape (free registration required) AND Antibiotic Rx adherence varies widely in sickle cell care – MedicalXpress (free)
Related guideline: Guideline on the management of acute chest syndrome in sickle cell disease – British Journal of Haematology (free)
Randomized Trial: Age of Red Cells for Transfusion and Outcomes in Critically Ill Adults
30 Sep, 2017 | 13:37h | UTC#LIVES2017 – Age of Red Cells for Transfusion and Outcomes in Critically Ill Adults – New England Journal of Medicine (free)
Commentaries: Red blood cells for transfusion like a good red: A little older, a little better – Monash University, via ScienceDaily (free) AND Is Older Blood OK to Use in a Transfusion? – WebMD (free)
Review: Acute and chronic hepatobiliary manifestations of sickle cell disease
30 Sep, 2017 | 13:13h | UTC
Guideline: Acute Lymphoblastic Leukemia
27 Sep, 2017 | 14:22h | UTCNCCN Guidelines Insights: Acute Lymphoblastic Leukemia, Version 1.2017 (free)
Randomized Controled Trial: Genotype-Guided Warfarin Dosing on Clinical Events and Anticoagulation Control
27 Sep, 2017 | 14:02h | UTCEffect of Genotype-Guided Warfarin Dosing on Clinical Events and Anticoagulation Control Among Patients Undergoing Hip or Knee Arthroplasty: The GIFT Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Genotyping Reduces Adverse Events with Warfarin – Cardiobrief (free) AND Genotype-Guided Warfarin Dosing Reduces Adverse Events After Hip, Knee Arthroplasty – Physician’s First Watch (free)
Review: Sickle Cell Disease
24 Sep, 2017 | 00:15h | UTCSickle Cell Disease – Gene Reviews (free)
Review: Evaluation of bleeding in patients receiving direct oral anticoagulants
20 Sep, 2017 | 21:11h | UTC
Review: Multiple Myeloma Emergencies
20 Sep, 2017 | 21:06h | UTCMultiple Myeloma Emergencies – emDocs (free)
Systematic Review: Optimisation of chemotherapy and radiotherapy for Hodgkin lymphoma patients
20 Sep, 2017 | 20:37h | UTCOriginal article: Optimisation of chemotherapy and radiotherapy for untreated Hodgkin lymphoma patients with respect to second malignant neoplasms, overall and progression-free survival: individual participant data analysis – Cochrane Library (link to abstract – $ for full-text)
Study: Blood Management Program Reduces Unnecessary Transfusions and Costs
18 Sep, 2017 | 14:54h | UTCImplementing a Health System–wide Patient Blood Management Program with a Clinical Community Approach – Anesthesiology (link to abstract – $ for full-text)
Commentary: Johns Hopkins Health System Reduces Unnecessary Transfusions With New Blood Management Program (free)
Related: High value quality improvement – High Value Practice Academic Alliance (free)
Review: Poems Syndrome
18 Sep, 2017 | 13:49h | UTCPoems Syndrome: an Update – Mediterranean Journal of Hematology and Infectious Diseases (free)
Guideline: Evaluation of the Neck Mass in Adults
12 Sep, 2017 | 21:09h | UTCSee also: Executive Summary (free) AND News Release (free)
Commentaries: Neck Mass in Adults: Guideline for Evaluation Provides Framework for Timely Diagnosis – NewsWise (free) AND Guidelines Issued on Evaluating Neck Masses – Physician’s First Watch (free)
Guideline: Iodine-based contrast media, multiple myeloma and monoclonal gammopathies
12 Sep, 2017 | 20:45h | UTC
Review: Multiple Myeloma Emergencies
9 Sep, 2017 | 22:43h | UTCMultiple Myeloma Emergencies – emDocs (free)
Meta-analysis: FDG PET/CT in Patients with Suspected Paraneoplastic Syndrome
9 Sep, 2017 | 14:34h | UTCCommentary: FDG PET/CT Helps Identify Malignancy Source in Paraneoplastic Syndrome – Medscape (free registration required)
Review: Anticoagulation Bridge Therapy in Patients with Atrial Fibrillation
7 Sep, 2017 | 22:03h | UTCSource: Hospital Medicine Virtual Journal Club (free)
Guideline: Diagnosis and empirical treatment of fever of unknown origin (FUO) in adult neutropenic patients
6 Sep, 2017 | 18:36h | UTCRelated Guidelines: Management of febrile neutropaenia: ESMO Clinical Practice Guidelines (free) AND Guideline for the Management of Fever and Neutropenia in Children With Cancer and Hematopoietic Stem-Cell Transplantation Recipients: 2017 Update (free)
Study: Effect of Palliative Care on Aggressiveness of End-of-Life Care Among Patients With Advanced Cancer
4 Sep, 2017 | 15:45h | UTCEffect of Palliative Care on Aggressiveness of End-of-Life Care Among Patients With Advanced Cancer – Journal of Oncology Practice (link to abstract – $ for full-text)
Commentaries: Palliative Care May Substantially Decrease Health-Care Utilization in Patients With Advanced Cancer – ASCO Post (free) AND End-of-Life Palliative Care Lowered Utilization for Patients With Cancer – AJMC (free) AND Palliative Care Cut Healthcare Use in Advanced Cancer – MedPage Today (free registration required)
Related guideline: Integration of Palliative Care Into Standard Oncology Care: American Society of Clinical Oncology Clinical Practice Guideline Update (free)
Study: Intra-articular versus Intravenous Application of Tranexamic Acid in Total Knee Arthroplasty
4 Sep, 2017 | 13:48h | UTCIntra-articular Application is More Effective Than Intravenous Application of Tranexamic Acid in Total Knee Arthroplasty: A Prospective Randomized Controlled Trial – Journal of Arthroplasty (link to abstract – $ for full-text)
Source: EvidenceAlerts
Guideline: Indication and Timing of Hematopoietic Cell Transplantation in Mature T-Cell and NK/T-Cell Lymphomas
4 Sep, 2017 | 13:57h | UTCClinical Practice Recommendations on Indication and Timing of Hematopoietic Cell Transplantation in Mature T-Cell and NK/T-Cell Lymphomas: an International Collaborative Effort on Behalf of the Guidelines Committee of the American Society for Blood and Marrow Transplantation (link to abstract – $ for full-text)
Commentary and Summary: Guideline on HCT for Certain Lymphoma Types – Hematology News (free registration required)
FDA approval brings first gene therapy to the United States
3 Sep, 2017 | 21:19h | UTCFDA News Release: FDA approval brings first gene therapy to the United States (free)
Commentaries: A $475,000 cancer drug: Wall Street sees ‘bargain’; patients see ‘completely broken’ system – HealthNewsReview (free) FDA Approves First CAR-T Cell Therapy for Pediatric Acute Lymphoblastic Leukemia – National Institutes of Health (free) AND FDA Approves First Gene-Altering Leukemia Treatment, Costing $475.000 – New York Times (10 articles per month are free) AND The FDA Approves a Landmark Cancer Drug – The Atlantic (free)
“…is a cancer therapy that represents several things at once: a game-changing way to treat cancer through genetic engineering, a novel paradigm for the biotech business, and the latest turn in the debate over just how astronomically expensive a life-saving therapy can be”. (from The Atlantic)