Global and Humanitarian Medicine | Page 2 of 18 | Links Medicus Content Curation & Alerts in Medicine

Summary: This systematic review analyzed the global burden of diabetes, including trends, projections, and attributions to risk factors. It considered data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), covering 204 countries and territories.

In 2021, an estimated 529 million people worldwide were living with diabetes. Regionally, the highest rates were observed in North Africa, the Middle East, and Oceania. Type 2 diabetes accounted for 96% of diabetes cases and 95.4% of diabetes DALYs (disability-adjusted life-years). More than half of global type 2 diabetes DALYs were attributable to high body mass index (BMI).

Predictions suggest that more than 1.31 billion people will have diabetes by 2050, with high prevalence rates in North Africa, the Middle East, and Latin America. The study notes the ongoing challenge of preventing and controlling type 2 diabetes, largely driven by increasing obesity. An understanding of disparities in risk profiles and disease burdens can inform strategies to control diabetes risk factors.

Article: Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021 – The Lancet

Editorial: Diabetes: a defining disease of the 21st century – The Lancet

News Release: Global diabetes cases to soar from 529 million to 1.3 billion by 2050 – Institute for Health Metrics and Evaluation

Commentary on Twitter (thread – click for more)

Today: More than 529 million people across the globe have diabetes

In the next 30 years: 1.3 billion people are projected to have diabetes
https://t.co/gh2O0K7RY0

— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) June 22, 2023

WHO outlines 40 research priorities on antimicrobial resistance

26 Jun, 2023 | 00:50h | UTC

News release: WHO outlines 40 research priorities on antimicrobial resistance – World Health Organization

Report: Global research agenda for antimicrobial resistance in human health – World Health Organization

Commentary on Twitter

🔥WHO published its 1st global research agenda for the world’s scientists to address the most urgent human health priorities to combat antimicrobial resistance
It outlines 40 research topics on drug-resistant bacteria,fungi& Mycobacterium TB
H/t @paimadhu https://t.co/AOVObnJK5Q pic.twitter.com/owZJwMIDXK

— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) June 22, 2023

WHO Report | Water, sanitation, hygiene, waste and electricity services in health care facilities

23 Jun, 2023 | 13:41h | UTC

Water, sanitation, hygiene, waste and electricity services in health care facilities: progress on the fundamentals – World Health Organization

News Release: Frontline health facilities faltering without water, sanitation, hygiene and electricity – WHO, UNICEF new report – World Health Organization

Commentary on Twitter (thread – click for more)

Better access to water, sanitation, hygiene & waste services in health facilities improve quality care and help prevent millions of deaths annually.

New WHO & @UNICEF Global Progress Report 2023 outlines how:
➡️ https://t.co/moyBs6yibC pic.twitter.com/Rv0P8DjzjA

— World Health Organization (WHO) (@WHO) June 13, 2023

Report | Global, regional, and national prevalence and mortality burden of sickle cell disease, 2000–2021

23 Jun, 2023 | 13:40h | UTC

Global, regional, and national prevalence and mortality burden of sickle cell disease, 2000–2021: a systematic analysis from the Global Burden of Disease Study 2021 – The Lancet Haematology

News Release: Sickle cell disease is 11 times more deadly than previously recorded – Institute for Health Metrics and Evaluation

Commentary on Twitter (thread – click for more)

Ahead of #WorldSickleCellDay #WSCD23 we are publishing the first detailed global estimates on the burden of #sicklecell disease

Read it #openaccess https://t.co/pVlWZ6s1G4

The authors show that mortality linked to #sicklecell disease is higher than previously described🧵 pic.twitter.com/WplWr0gXqJ

— The Lancet Haematology (@TheLancetHaem) June 16, 2023

Global Analysis | Disease burden linked to unsafe domestic water, sanitation, and hygiene

16 Jun, 2023 | 13:52h | UTC

Burden of disease attributable to unsafe drinking water, sanitation, and hygiene in domestic settings: a global analysis for selected adverse health outcomes – The Lancet

Opinion | Threats by artificial intelligence to human health and human existence

14 Jun, 2023 | 14:47h | UTC

Threats by artificial intelligence to human health and human existence – BMJ Global Health

News Release: Doctors and public health experts join calls for halt to AI R&D until it’s regulated – BMJ Newsroom

Review | Wastewater monitoring can anchor global disease surveillance systems

13 Jun, 2023 | 14:07h | UTC

Wastewater monitoring can anchor global disease surveillance systems – The Lancet Global Health

Wastewater network infrastructure in public health: Applications and learnings from the COVID-19 pandemic – PLOS Global Public Health

Opinion: Wastewater analysis can be a powerful public health tool—if it’s done sensibly.

CDC unveils its latest weapon in Covid-19 detection: wastewater.

CDC Report: Using Wastewater Surveillance Data to Support the COVID-19 Response — United States, 2020–2021.

Rapid, large-scale wastewater surveillance and automated reporting system enabled early detection of nearly 85% of COVID-19 cases on a University campus.

[Preprint] Wastewater genomic testing can effectively track COVID-19 variants of concern.

Human Waste Could Be The Next Big Weapon in Controlling COVID-19 – TIME

Next steps for wastewater testing to help end this pandemic — and prevent the next one – STAT

Sewage sleuths helped an Arizona town beat back Covid-19. For wastewater epidemiology, that’s just the start – STAT

The myriad ways sewage surveillance is helping fight COVID around the world – Nature

Testing sewage can give school districts, campuses and businesses a heads-up on the spread of COVID-19 – The Conversation

It’s time to begin a national wastewater testing program for Covid-19 – STAT

Coronavirus: Testing sewage an ‘easy win’ – BBC

Development of wastewater pooled surveillance of SARS-CoV-2 from congregate living settings – high sensitivity, but unable to distinguish new infectious cases from persistent convalescent shedding.

AHA Scientific Statement | Contaminant metals as cardiovascular risk factors

13 Jun, 2023 | 14:04h | UTC

Contaminant metals as cardiovascular risk factors: a scientific statement from the American Heart Association – Journal of the American Heart Association

News Release: Chronic exposure to lead, cadmium and arsenic increases risk of cardiovascular disease – American Heart Association

Top Things to Know: Contaminant Metals as CV Risk Factors – American Heart Association

Commentary: Toxic Metals: The Poisons that are “Killing Us Softly” – American Heart Association

Commentary on Twitter

⚠️ Chronic exposure to lead, cadmium & arsenic ⬆️ risk of CVD

Monitoring exposure in 💨, 💧& 🌱is important for reducing inequity in CVD risk, according to a new AHA scientific statement published in @JAHA_AHA

✍️ @GLamasMD @anavasac https://t.co/v5TOvvettD pic.twitter.com/36iCmfDmDP

— AHA Science (@AHAScience) June 12, 2023

M-A | Kangaroo mother care reduces mortality in preterm and low birth weight infants

13 Jun, 2023 | 13:41h | UTC

Kangaroo mother care for preterm or low birth weight infants: a systematic review and meta-analysis – BMJ Global Health

News Release: Effects of KMC in preterm and low birth weight infants – BMJ / News Medical

Immediate “Kangaroo Mother Care” and Survival of Infants with Low Birth Weight – New England Journal of Medicine

Effect of community-initiated kangaroo mother care on survival of infants with low birthweight: a randomised controlled trial – The Lancet

Effect of Community-Initiated Kangaroo Mother Care on Postpartum Depressive Symptoms and Stress Among Mothers of Low-Birth-Weight Infants: A Randomized Clinical Trial – JAMA Network Open

Kangaroo mother care to reduce morbidity and mortality in low birthweight infants – Cochrane Library

Preterm care during the COVID-19 pandemic: A comparative risk analysis of neonatal deaths averted by kangaroo mother care versus mortality due to SARS-CoV-2 infection – EclinicalMedicine

Review | Drivers of inappropriate antibiotic use in low- and middle-income countries

12 Jun, 2023 | 13:35h | UTC

Drivers of inappropriate antibiotic use in low- and middle-income countries – JAC-Antimicrobial Resistance

Review | Integrating eye care in low-income and middle-income settings

6 Jun, 2023 | 14:21h | UTC

Integrating eye care in low-income and middle-income settings: a scoping review – BMJ Open

M-A | Significant non-alcoholic fatty liver disease prevalence in South Asia, many non-obese affected

6 Jun, 2023 | 14:00h | UTC

Prevalence and associated factors for non-alcoholic fatty liver disease among adults in the South Asian Region: a meta-analysis – The Lancet Regional Health – Southeast Asia

Global burden, risk factors analysis, and prediction study of ischemic stroke, 1990–2030

5 Jun, 2023 | 13:53h | UTC

Global Burden, Risk Factors Analysis, and Prediction Study of Ischemic Stroke, 1990–2030 – Neurology

News Release: Worldwide Stroke Deaths Expected to Increase to Nearly 5 Million by 2030 – American Academy of Neurology

Commentary on Twitter

Published online: Global Burden, Risk Factors Analysis, and Prediction Study of Ischemic #Stroke, 1990–2030 https://t.co/nIH5mBQDtE #NeuroTwitter pic.twitter.com/WUfFQM5t7Z

— Neurology Journal (@GreenJournal) May 23, 2023

Global, regional, and national burden of low back pain, 1990–2020, its attributable risk factors, and projections to 2050

2 Jun, 2023 | 12:34h | UTC

Global, regional, and national burden of low back pain, 1990–2020, its attributable risk factors, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021 – The Lancet Rheumatology

Editorial: The global epidemic of low back pain – The Lancet Rheumatology

News Releases:

New study shows low back pain is the leading cause of disability around the world – Institute for Health Metrics and Evaluation

In 2050, over 800 million people globally estimated to be living with back pain – The University of Sidney

Commentary on Twitter

NEW—GBD 2021 data published in @TheLancetRheum finds low back pain is the leading cause of disability globally. #LowBackPain affects 619 million individuals (1 out of every 13 people). More women across all age groups suffered from low back pain than men.https://t.co/A2RoU9hn9p pic.twitter.com/vhXwcVh1e7

— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) May 22, 2023

WHO Report | Global progress in tackling maternal and newborn deaths stalls since 2015

25 May, 2023 | 11:36h | UTC

News Release: Global progress in tackling maternal and newborn deaths stalls since 2015: UN – World Health Organization

Report: Improving maternal and newborn health and survival and reducing stillbirth – Progress report 2023 – World Health Organization

WHO Report | World health statistics 2023

23 May, 2023 | 13:16h | UTC

World health statistics 2023: monitoring health for the SDGs, sustainable development goals – World Health Organization

News Release: Urgent action needed to tackle stalled progress on health-related Sustainable Development Goals – World Health Organization

Commentary on Twitter (thread – click for more)

📌World Health Statistics 2023 report is out.
It is WHO’s ‘annual check-up on the state of the world’s health’.
⏩New figures on the impact of the #COVID19 pandemic
⏩Latest statistics on progress towards health-related Sustainable Development Goals.
🔗https://t.co/ESpUv3mEh4 pic.twitter.com/i0zrsy0IdH

— World Health Organization (WHO) (@WHO) May 19, 2023

WHO Report | 152 million babies born preterm in the last decade

23 May, 2023 | 13:15h | UTC

News Release: 152 million babies born preterm in the last decade – World Health Organization

Report: Born too soon: decade of action on preterm birth – World Health Organization

The Lancet Series | Small vulnerable newborns

23 May, 2023 | 13:13h | UTC

News Release: An estimated 1 million stillbirths and newborn baby deaths could be prevented each year with low-cost solutions – Lancet

Homepage: Small vulnerable newborns – The Lancet (free registration required for all articles)

Small vulnerable newborns—big potential for impact

Small babies, big risks: global estimates of prevalence and mortality for vulnerable newborns to accelerate change and improve counting

Biological and pathological mechanisms leading to the birth of a small vulnerable newborn

Evidence-based antenatal interventions to reduce the incidence of small vulnerable newborns and their associated poor outcomes

The ethical, economic, and developmental imperative to prevent small vulnerable newborns and stillbirths: essential actions to improve the country and global response

Global variations in heart failure etiology, management, and outcomes

22 May, 2023 | 13:50h | UTC

Global Variations in Heart Failure Etiology, Management, and Outcomes – JAMA (free for a limited period)

Author Interview: Global Trends in Heart Failure Etiology, Management, and Outcomes

News Release: Heart failure deadly and under-treated in most countries, says a study in 40 countries – McMaster University

Commentary on Twitter

Study of patients with heart failure (HF) from 40 different countries and from 4 different economic levels demonstrated differences in HF etiologies, management, and outcomes. https://t.co/uYH9jI8Q5Z

— JAMA (@JAMA_current) May 16, 2023

Cluster RCT | Early detection and treatment bundle reduces postpartum hemorrhage complications

16 May, 2023 | 15:02h | UTC

Summary: An international, cluster-randomized trial assessed the effectiveness of a multicomponent clinical intervention for postpartum hemorrhage in patients having vaginal delivery. The study involved 80 secondary-level hospitals across Kenya, Nigeria, South Africa, and Tanzania, with 210,132 patients. The intervention group utilized a calibrated blood-collection drape for early detection of postpartum hemorrhage and a first-response treatment bundle, while the control group received usual care.

The primary outcome measured was a composite of severe postpartum hemorrhage (blood loss ≥1000 ml), laparotomy for bleeding, or maternal death from bleeding. The results showed a significant reduction in primary-outcome events in the intervention group (1.6%) compared to the usual-care group (4.3%) with a risk ratio of 0.40 (95% CI, 0.32 to 0.50; P<0.001). Postpartum hemorrhage detection rates were 93.1% and 51.1% in the intervention and usual-care groups, respectively, and treatment bundle adherence was 91.2% and 19.4%, respectively.

These findings demonstrate that early detection of postpartum hemorrhage and the use of a bundled treatment approach can significantly reduce the risk of severe postpartum hemorrhage, laparotomy for bleeding, or death from bleeding among patients having vaginal delivery. The results have important implications for improving clinical practice and reducing postpartum hemorrhage complications globally.

Article: Randomized Trial of Early Detection and Treatment of Postpartum Hemorrhage – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Lifesaving solution dramatically reduces severe bleeding after childbirth – World Health Organization

Commentary on Twitter

In a large, cluster-randomized trial involving patients with PPH after vaginal delivery, a multicomponent intervention lowered the risk of severe PPH, laparotomy for bleeding, or maternal death from bleeding. Full results of the E-MOTIVE trial: https://t.co/NjcE4Q1rxM #IMNHC2023

— NEJM (@NEJM) May 9, 2023

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