Family Medicine | Page 48 of 374 | Links Medicus Content Curation & Alerts in Medicine

Study showing FRAIL scale association with 30-d & 6 mo mortality, postop complications, & delirium.Odds ratios are nice but actual% may be more helpful.If OR is 3 but % complications is 0.5%, it’s not that meaningful.Need both for informed decision-makinghttps://t.co/V5qfEDHslQ

— Steven Cohn, MD (@preopconsult) November 30, 2022

Cohort Study | Tobacco smoking and risks of more than 470 diseases in China.

2 Dec, 2022 | 14:14h | UTC

Tobacco smoking and risks of more than 470 diseases in China: a prospective cohort study – The Lancet Public Health

Commentary: Smoking increases the risks of 56 diseases in Chinese adults – Oxford University

WHO Pocket book of primary health care for children and adolescents.

1 Dec, 2022 | 14:09h | UTC

Pocket book of primary health care for children and adolescents: guidelines for health promotion, disease prevention and management from the newborn period to adolescence (2022) – World Health Organization

Phase 2b RCT | Cannabidiol oil failed to relieve symptoms in advanced cancer.

1 Dec, 2022 | 14:04h | UTC

Phase IIb Randomized, Placebo-Controlled, Dose-Escalating, Double-Blind Study of Cannabidiol Oil for the Relief of Symptoms in Advanced Cancer (MedCan1-CBD) – Journal of Clinical Oncology

Commentary: Cannabis oil failed to improve pain or quality of life in palliative care cancer patients, study shows – The Guardian

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Systematic Review: Cannabis-based products for chronic pain.

Podcast: #338 LIVE! Medical Cannabis: Is it still dope? – The Curbsiders

Medicinal Cannabis for Chronic Pain: The Bermuda Triangle of Low Quality Studies, Countless Meta-analyses and Conflicting Recommendations – European Journal of Pain

RCT: Effect of medical marijuana card ownership on pain, insomnia, and affective disorder symptoms in adults.

Cohort Study: Long-term cannabis use is associated with cognitive deficits and smaller hippocampal volume in midlife.

AHA Scientific Statement | How does cannabis use affect brain health? Caution advised, more research needed.

M-A: Birth outcomes of neonates exposed to marijuana in utero.

Review: Cannabis-based medicines and medical cannabis for chronic neuropathic pain.

Cannabinoid metabolites as inhibitors of major hepatic CYP450 enzymes, with implications for cannabis-drug interactions.

The International Cannabis Toolkit (iCannToolkit): a multidisciplinary expert consensus on minimum standards for measuring cannabis use.

Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.

Guideline: Medical cannabis or cannabinoids for chronic pain.

Cannabis and Cannabinoid Analgesia position statement – “Due to the lack of high-quality clinical evidence, the IASP does not currently endorse general use of cannabis and cannabinoids for pain relief.”

NICE Guideline: Cannabis-Based Medicinal Products

Consensus recommendations for perioperative management of cannabis and cannabinoid-based medicine users

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Short Review: Drug Interactions with Cannabinoids

Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain

Review: Considerations for cannabinoids in perioperative care by anesthesiologists.

Review: Cannabis-based Medicines and the Perioperative Physician

Study: Cannabis Use Disorder May Increase the Risk of Cardiovascular Events in Major Elective Surgeries

Perspective: If You Smoke Pot, Your Anesthesiologist Needs To Know

Perioperative Care of Cannabis Users: A Comprehensive Review of Pharmacological and Anesthetic Considerations

M-A | Efficacy and safety of COVID-19 inactivated vaccine.

1 Dec, 2022 | 14:00h | UTC

Efficacy and safety of COVID-19 inactivated vaccine: A meta-analysis – Frontiers in Medicine

Collection of Cochrane evidence on diagnosing tuberculosis.

1 Dec, 2022 | 13:56h | UTC

Collection of Cochrane evidence on diagnosing tuberculosis – Cochrane Library

2ry analysis of a RCT | Vitamin D supplementation did not influence growth, body composition, and pubertal development in children.

30 Nov, 2022 | 13:49h | UTC

Influence of Vitamin D Supplementation on Growth, Body Composition, and Pubertal Development Among School-aged Children in an Area With a High Prevalence of Vitamin D Deficiency: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)

Commentary: Vitamin D Supplementation Does Not Influence Growth in Children – HealthDay

ACP Guidance | Outpatient treatment of confirmed COVID-19.

30 Nov, 2022 | 13:54h | UTC

Outpatient Treatment of Confirmed COVID-19: Living, Rapid Practice Points From the American College of Physicians (Version 1) – Annals of Internal Medicine

Editorial: Ongoing Need for Clinical Trials and Contemporary End Points for Outpatient COVID-19 – Annals of Internal Medicine

Commentary: New ACP living practice points, mortality data on COVID-19 – ACP Internist

Cohort Study | Acute and postacute sequelae associated with SARS-CoV-2 reinfection.

30 Nov, 2022 | 13:42h | UTC

Acute and postacute sequelae associated with SARS-CoV-2 reinfection – Nature Medicine

News Release: Repeat COVID-19 infections increase risk of organ failure, death – Washington University School of Medicine

Commentary: SARS-CoV-2 Reinfection Ups Risks for Death, Hospitalization – HealthDay

German guideline on diverticular disease/diverticulitis.

30 Nov, 2022 | 13:41h | UTC

German guideline diverticular disease/diverticulitis: Part I: Methods, pathogenesis, epidemiology, clinical characteristics (definitions), natural course, diagnosis and classification – UEG Journal

Editorial: New German guidelines for the management of diverticulitis – UEG Journal

Systematic Review: Antibiotics for uncomplicated diverticulitis.

Efficacy and Safety of Non-Antibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-Label, Non-Inferiority Trial – Annals of Surgery (link to abstract – $ for full-text)

The WSES/SICG/ACOI/SICUT/AcEMC/SIFIPAC guidelines for diagnosis and treatment of acute left colonic diverticulitis in the elderly – World Journal of Emergency Surgery

Diagnosis and Management of Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians – Annals of Internal Medicine

Colonoscopy for Diagnostic Evaluation and Interventions to Prevent Recurrence After Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians – Annals of Internal Medicine

Changing Paradigms in the Management of Acute Uncomplicated Diverticulitis – Scandinavian Journal of Surgery

Elective surgical management of diverticulitis – Current Problems in Surgery

Management of Colonic Diverticulitis – Agency for Healthcare Research and Quality

2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting – World Journal of Emergency Surgery

The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Treatment of Left-Sided Colonic Diverticulitis – Diseases of the Colon & Rectum

WHO renames “monkeypox” as “mpox” to help destigmatize the disease.

29 Nov, 2022 | 14:27h | UTC

WHO recommends new name for monkeypox disease – World Health Organization

Commentaries:

WHO to phase out the name ‘monkeypox’ for ‘mpox’ – STAT

WHO renames monkeypox as mpox, citing racist stigma – NPR

The Future of Monkeypox – The Atlantic

Monkeypox given new name by global health experts – BBC

Monkeypox to be renamed mpox to avoid stigma, says WHO – The Guardian

Commentary on Twitter (thread – click for more)

Following consultations, WHO will begin using a new term for “#monkeypox” disease: '#mpox'.
Both names will be used simultaneously for one year while 'monkeypox' is phased out https://t.co/VT9DAdYrGY pic.twitter.com/Ae6zgkefPI

— World Health Organization (WHO) (@WHO) November 28, 2022

M-A | Thiazide diuretics and fracture risk.

29 Nov, 2022 | 14:23h | UTC

Thiazide Diuretics and Fracture Risk: A Systematic Review and Meta-Analysis of Randomized Clinical Trials – JBMR Plus

Podcast | Back pain update.

29 Nov, 2022 | 14:07h | UTC

#368 Back Pain Update with
Dr. Austin Baraki – The Curbsiders

Review | Infectious complications of abortion.

29 Nov, 2022 | 13:56h | UTC

Infectious Complications of Abortion – Open Forum Infectious Diseases

2023 GOLD Report | Global strategy for prevention, diagnosis and management of COPD.

27 Nov, 2022 | 22:32h | UTC

2023 GOLD REPORT: global strategy for prevention, diagnosis and management of COPD: 2023 Report – Global Initiative for Chronic Obstructive Lung Disease

Seminar | Monkeypox.

27 Nov, 2022 | 22:29h | UTC

Monkeypox – The Lancet

Commentaries:

Study shows there is substantial monkeypox transmission before symptoms appear.

Global monkeypox case hospitalisation rates: A rapid systematic review and meta-analysis – eClinicalMedicine

Human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks: a global case series – The Lancet

Monkeypox — A Sobering Sentinel for Pandemic Preparedness and Sexual Health System Capacity – New England Journal of Medicine

CDC study shows healthcare workers have a low risk of infection after exposure to patients with monkeypox.

Monkeypox – New England Journal of Medicine

Diagnosis and Management of Monkeypox: A Review for the Emergency Clinician – Annals of Emergency Medicine

Monkeypox: disease epidemiology, host immunity and clinical interventions.

Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health

Cohort Study | Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain.

CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.

Update on the Monkeypox Outbreak – JAMA

Antivirals with Activity Against Monkeypox: A Clinically Oriented Review – Clinical Infectious Diseases

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases

Commentary on Twitter

Seminar: Monkeypox

In light of the 2022 global outbreak, @oriolmitja and colleagues provide an overview of epidemiology, clinical presentation, treatment, prevention, and more.

📌 https://t.co/gB0fcokA8D pic.twitter.com/Db3ZsU4ykt

— The Lancet (@TheLancet) November 22, 2022

SR | E-cigarettes are more effective than traditional nicotine-replacement methods in helping people quit smoking.

27 Nov, 2022 | 22:26h | UTC

Electronic cigarettes for smoking cessation – Cochrane Library

News Release: E-cigarettes are more effective than nicotine-replacement therapy in helping smokers quit – University of Oxford

Commentaries:

Latest Cochrane Review finds high certainty evidence that nicotine e-cigarettes are more effective than traditional nicotine-replacement therapy (NRT) in helping people quit smoking – Cochrane Library

Expert reaction to Cochrane review on electronic cigarettes for smoking cessation – Science Media Centre

Commentary on Twitter

Published today! Updated w/ 17 new studies @CochraneLibrary living review of #ecig to #QuitSMOKING. Now high certainty evidence nicotine #vapes help more people to quit at 6 mths+ than NRT. @CRUK_Policy funded https://t.co/68FBih1nVg pic.twitter.com/euKXCxLJLk

— CochraneTAG (@CochraneTAG) November 17, 2022

Improving antimicrobial stewardship with penicillin allergy testing: a review of current practices and unmet needs.

27 Nov, 2022 | 22:25h | UTC

Improving antimicrobial stewardship with penicillin allergy testing: a review of current practices and unmet needs – JAC-Antimicrobial Resistance

Management of Patients with Suspected or Confirmed Antibiotic Allergy. Executive Summary of Guidance from the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Society of Allergy and Clinical Immunology (SEAIC), the Spanish Society of Hospital Pharmacy (SEFH) and the Spanish Society of Intensive Medicine and Coronary Care Units (SEMICYUC) – Journal of Investigational Allergology and Clinical Immunology (PDF)

The prevalence of penicillin allergy labeling ranged from 0.9% to 10.2% across practices in a large pediatric cohort, raising questions regarding the validity of those labels and the unnecessary use of second-line antibiotics that may follow.

M-A: Most patients with allergy to Penicillin can be given Cefazolin

Systematic review: Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge

Penicillin allergy labels increase second-line broad-spectrum antibiotic prescribing for pediatric respiratory tract infections

Podcast: A Clinical Pharmacologist’s Perspective on Penicillin Allergy

Study: Development and Validation of a Penicillin Allergy Clinical Decision Rule

Management of a surgical patient with a label of penicillin allergy: narrative review and consensus recommendations – British Journal of Anaesthesia

NICE: Double Check Patients with ‘Penicillin Allergy’ to Avoid Increased MRSA Risk

Cohort Study: Risk of Meticillin Resistant Staphylococcus Aureus and Clostridium Difficile in Patients with a Documented Penicillin Allergy

Consensus Paper | General approaches to medical management of menstrual suppression.

27 Nov, 2022 | 22:21h | UTC

General Approaches to Medical Management of Menstrual Suppression: ACOG Clinical Consensus No. 3 – Obstetrics & Gynecology

M-A | Effectiveness of home-based exercise delivered by digital health in older adults.

27 Nov, 2022 | 22:20h | UTC

Effectiveness of home-based exercise delivered by digital health in older adults: a systematic review and meta-analysis – Age and Ageing

Commentary on Twitter

Effectiveness of home-based exercise delivered by digital health in older adults: a systematic review and meta-analysis

👀👀👇👇https://t.co/OYXM6tzNGr pic.twitter.com/VNnURqQQHz

— Physio Meets Science (@PhysioMeScience) November 16, 2022