Family Medicine
Endocervical sampling in women with suspected cervical neoplasia: a meta-analysis of diagnostic test accuracy studies.
9 Dec, 2022 | 13:12h | UTC
Cohort Study | Comparative safety of antiseizure medication monotherapy in pregnancy for major malformations.
9 Dec, 2022 | 13:10h | UTCComparative safety of antiseizure medication monotherapy for major malformations – Annals of Neurology (link to abstract – $ for full-text)
Related:
Risks of 23 Specific Malformations Associated with Prenatal Exposure to 10 Antiepileptic Drugs
Research: Topiramate Use Early in Pregnancy and the Risk of Oral Clefts
Educational attainment of children born to mothers with epilepsy – Journal of Neurology, Neurosurgery, and Psychiatry (link to abstract – $ for full-text)
Preliminary study suggests that Edoxaban is a safe alternative for preventing thromboembolism in pediatric patients with cardiac disease.
9 Dec, 2022 | 13:07h | UTCEdoxaban for Thromboembolism Prevention in Pediatric Patients With Cardiac Disease – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Guideline | Management of individuals with diabetes at high risk for hypoglycemia.
8 Dec, 2022 | 13:08h | UTC
SR | Efficacy and safety of COVID‐19 vaccines.
8 Dec, 2022 | 13:04h | UTCEfficacy and safety of COVID‐19 vaccines – Cochrane Library
Summary: What are the benefits and risks of vaccines for preventing COVID-19? – Cochrane Library
Commentary: Are COVID-19 vaccines effective and safe? New Cochrane evidence – Evidently Cochrane
Cohort Study | Association of in utero antipsychotic medication exposure with risk of congenital malformations.
8 Dec, 2022 | 13:00h | UTCAssociation of In Utero Antipsychotic Medication Exposure With Risk of Congenital Malformations in Nordic Countries and the US – JAMA Psychiatry (free for a limited period)
Related:
Commentary on Twitter
New findings from a large cohort study including 26,000 antipsychotic-exposed pregnancies from 6 countries suggest that prenatal exposure to individual antipsychotics is generally not associated with an increase in risk of major congenital malformations https://t.co/4cUm8sXgsi
— JAMA Psychiatry (@JAMAPsych) December 7, 2022
Cohort Study | Poor R-wave progression as a predictor of sudden cardiac death in the general population and subjects with CAD.
8 Dec, 2022 | 12:58h | UTCCommentary: Poor R-wave progression is linked to sudden cardiac death: Study – Medical Dialogues
Commentary on Twitter
Poor R-wave progression as a predictor of sudden cardiac death in the general population and subjects with coronary artery disease – OPEN ACCESS! https://t.co/ScaZVvsbCU
— HeartRhythm (@hrs_journal) June 7, 2022
ACC/AHA/HFSA 2022 and ESC 2021 guidelines on heart failure comparison.
8 Dec, 2022 | 12:57h | UTCACC/AHA/HFSA 2022 and ESC 2021 guidelines on heart failure comparison – ESC Heart Failure
Original Guidelines:
#ACC22 – 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.
Podcast | Disease-modifying nutrition.
8 Dec, 2022 | 12:48h | UTC#360 Disease-Modifying Nutrition with Dr. Michelle McMacken – The Curbsiders
RCT | Effect of Vitamin C for pregnant smokers on offspring airway function and wheeze at age 5 years.
8 Dec, 2022 | 12:47h | UTCEffect of Vitamin C Supplementation for Pregnant Smokers on Offspring Airway Function and Wheeze at Age 5 Years: Follow-up of a Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)
News Release: Researchers discover that vitamin C improves health for children of pregnant smokers – Oregon Health & Science University
Commentary on Twitter
This study found that offspring of pregnant smokers who were randomized to Vitamin C supplementation during pregnancy had increase airway function at age 5 years and decreased wheeze. https://t.co/yXSBzJlkIq #Research
— JAMA Pediatrics (@JAMAPediatrics) November 21, 2022
ASCO Guideline | Use of opioids for adults with pain from cancer or cancer treatment.
7 Dec, 2022 | 14:32h | UTC
M-A | Efficacy of dual and triple combination inhaler therapies compared with each other and varying doses of inhaled corticosteroids in asthma.
7 Dec, 2022 | 14:26h | UTC
M-A | Micronutrient supplementation to reduce cardiovascular risk.
7 Dec, 2022 | 14:25h | UTCMicronutrient Supplementation to Reduce Cardiovascular Risk – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries:
Micronutrient Supplementation to Reduce Cardiovascular Risk – American College of Cardiology
Study Identifies Some Supplements That Benefit CV Health – American College of Cardiology
Cohort Study | Adding salt to foods linked to increased risk of cardiovascular disease.
6 Dec, 2022 | 14:04h | UTCAdding Salt to Foods and Risk of Cardiovascular Disease – Journal of the American College of Cardiology (link to abstract – $ for full-text)
News Release: Shaking less salt on your food at the table could reduce heart disease risk – American College of Cardiology
Commentaries:
Adding Salt to Food and Risk of Cardiovascular Disease – American College of Cardiology
Lower Frequency of Adding Salt to Food Linked to Lower CVD Risk – HealthDay
Case Report | Vitamin D intoxication and severe hypercalcemia complicating nutritional supplements misuse.
6 Dec, 2022 | 13:56h | UTCCommentaries:
Vitamin D supplement ‘overdosing’ is possible and harmful, warn doctors – Medical Dialogues
How an increasingly popular supplement landed a man in the hospital – CNN
You Can Take Too Much Vitamin D — One Man Found Out the Hard Way – HealthDay
Monkeypox in pregnancy: virology, clinical presentation, and obstetric management.
6 Dec, 2022 | 13:58h | UTCRelated:
WHO renames “monkeypox” as “mpox” to help destigmatize the disease.
Study shows there is substantial monkeypox transmission before symptoms appear.
Monkeypox – New England Journal of Medicine
Monkeypox: disease epidemiology, host immunity and clinical interventions.
Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health
CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.
Update on the Monkeypox Outbreak – JAMA
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
Podcast | Parkinson’s Disease for primary care.
6 Dec, 2022 | 13:43h | UTC#370 Parkinson’s Disease for Primary Care with Dr. Albert Hung – The Curbsiders
New WHO report showcases strategies to keep children safe online.
5 Dec, 2022 | 00:24h | UTCNews Release: New report showcases strategies to keep children safe online – World Health Organization
Report: What works to prevent violence against children online? – World Health Organization
Commentary on Twitter (thread – click for more)
🆕 report by WHO on what works to prevent online violence against children, addressing the growing worldwide concern of keeping children safe online
📌 https://t.co/pDL1l2TKkT pic.twitter.com/uPCJoiIblK
— World Health Organization (WHO) (@WHO) December 2, 2022
Choosing Wisely | Five things physicians and patients should question in the practice of pediatric emergency medicine.
5 Dec, 2022 | 00:22h | UTCSee complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Guideline Summary | Evaluation and management of gastroesophageal reflux disease.
5 Dec, 2022 | 00:18h | UTCOriginal Guideline: ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease – American Journal of Gastroenterology
Related Guidelines:
ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease.
SAGES guidelines for the surgical treatment of gastroesophageal reflux.
Guideline on Screening for Esophageal Adenocarcinoma in Patients with Chronic GERD
NICE Guideline: Gastro-esophageal Reflux Disease and Dyspepsia in Adults
NICE Guideline: Gastroesophageal Reflux Disease in Children and Young People
Cohort Study | Viral shedding 1 year following first-episode genital HSV-1 infection.
5 Dec, 2022 | 00:14h | UTCViral Shedding 1 Year Following First-Episode Genital HSV-1 Infection – JAMA (free for a limited period)
Editorial: Shedding Patterns of Genital Herpes Simplex Virus Infections – JAMA (free for a limited period)
News Release: Viral shedding ebbs over time with HSV-1 genital infections – University of Washington School of Medicine
Commentary: Viral Shedding Common After First-Episode Genital HSV-1 Infection – HealthDay
Commentary on Twitter
In this study, genital herpes simplex virus type 1 (HSV-1) shedding was frequent after first-episode genital HSV-1 and declined rapidly during the first year of infection. https://t.co/CsVr1tNfNQ
— JAMA (@JAMA_current) October 26, 2022
M-A | Treatment of depression after acute coronary syndrome.
5 Dec, 2022 | 00:03h | UTC
Consensus Recommendations | Antiretroviral drugs for treatment and prevention of HIV infection in adults.
2 Dec, 2022 | 14:45h | UTCAntiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults2022 Recommendations of the International Antiviral Society–USA Panel – JAMA (free for a limited period)
Invited Commentary: Ending the HIV Epidemic: We Have the Tools, Do We Have the Will? – JAMA (free for a limited period)
Author Interview: Advances in Treatment and Prevention of HIV – JAMA
RCT | Lecanemab slows cognitive decline in early Alzheimer’s disease but raises safety concerns.
2 Dec, 2022 | 14:40h | UTCLecanemab in Early Alzheimer’s Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries:
Heralded Alzheimer’s drug works — but safety concerns loom – Nature
Lecanemab and Alzheimer’s: More Data – Science
Alzheimer’s Drug is Hailed Amid Safety Concerns – Health Policy Watch
Related: Second death linked to potential antibody treatment for Alzheimer’s disease – Science
Commentary on Twitter
In a phase 3 trial, participants with early Alzheimer’s disease who received the monoclonal antibody lecanemab had less decline on measures of cognitive function at 18 months than those who received placebo. https://t.co/NjEloWVk1V pic.twitter.com/n33yjV9117
— NEJM (@NEJM) November 30, 2022
Cohort Study | Buprenorphine may be a safer option than Methadone for opioid use disorder in pregnancy.
2 Dec, 2022 | 14:42h | UTCBuprenorphine versus Methadone for Opioid Use Disorder in Pregnancy – New England Journal of Medicine (link to abstract – $ for full-text)