Family Medicine
Brain fog can persist for months after COVID diagnosis.
28 Oct, 2021 | 10:13h | UTCAssessment of Cognitive Function in Patients After COVID-19 Infection – JAMA Network Open
Commentaries:
Brain fog can persist 8 months after COVID diagnosis – CIDRAP
What COVID vaccines for young kids could mean for the pandemic.
28 Oct, 2021 | 10:15h | UTCWhat COVID vaccines for young kids could mean for the pandemic – Nature
Related: FDA advisory panel recommends Pfizer Covid-19 vaccine be authorized for children ages 5 to 11.
Retrospective cohort study: corticosteroid treatment linked to lower odds of surgical drainage among pediatric patients with retropharyngeal and parapharyngeal abscesses.
28 Oct, 2021 | 09:52h | UTC
RCT: Extended follow-up of local steroid injection for carpal tunnel syndrome.
28 Oct, 2021 | 09:46h | UTC
Commentary on Twitter
In carpal tunnel syndrome, this randomized trial of local steroid vs placebo injection shows similar symptom severity score improvement but a significant small reduction in rate of and longer time to surgery after steroid. @IsamAtroshi @jonasranstam https://t.co/s5LibRnFaV
— JAMA Network Open (@JAMANetworkOpen) October 22, 2021
Review: Genome sequencing as a diagnostic test.
28 Oct, 2021 | 09:42h | UTCGenome sequencing as a diagnostic test – Canadian Medical Association Journal
Breakthrough infections occur in those with lower antibody levels.
27 Oct, 2021 | 01:45h | UTCOriginal study: Covid-19 Breakthrough Infections in Vaccinated Health Care Workers – New England Journal of Medicine
Mix-and-match COVID vaccines ace the effectiveness test – “No need for brand loyalty”.
27 Oct, 2021 | 01:42h | UTCMix-and-match COVID vaccines ace the effectiveness test – Nature
Related:
Should You Mix and Match Your Booster Shot?
A primer on what we know about mixing and matching Covid vaccines.
Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination.
RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.
Heterologous AstraZeneca/Pfizer vaccination seems to be associated with increased effectiveness against Covid-19 compared to homologous Pfizer/Pfizer vaccination.
27 Oct, 2021 | 01:44h | UTCImmunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination – Nature
Related:
Should You Mix and Match Your Booster Shot?
A primer on what we know about mixing and matching Covid vaccines.
Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination.
RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.
Commentary on Twitter
A dose of the AstraZeneca COVID-19 vaccine followed by a dose of the Pfizer/BioNTech vaccine confers better protection against SARS-CoV-2 infection than two doses of the Pfizer vaccine, according to a study in healthcare workers published in @Nature. https://t.co/6hIVkiOLQ1 pic.twitter.com/AmsyVUMpoj
— Nature Portfolio (@NaturePortfolio) October 26, 2021
UEG Consensus on Functional Dyspepsia.
27 Oct, 2021 | 01:32h | UTC
Anticoagulants and diabetes agents are among the most frequent causes of emergency department visits attributed to medication harms.
27 Oct, 2021 | 01:15h | UTCUS Emergency Department Visits Attributed to Medication Harms, 2017-2019 – JAMA (link to abstract – $ for full-text)
Commentaries:
Number of emergency room visits for medication harms increases with age – MedicalResearch.com
Blood thinners, diabetes meds among top causes of drug-related ER visits – UPI
Systematic Review: Antibiotics for the treatment of COVID‐19 – “We are certain that risk of death in hospitalized COVID‐19 patients is not reduced by treatment with azithromycin after 28 days”.
26 Oct, 2021 | 02:07h | UTCAntibiotics for the treatment of COVID‐19 – Cochrane Library
Commentary on Twitter
JUST PUBLISHED – Are #antibiotics an effective treatment for #COVID19 & do they cause unwanted effects? https://t.co/EVHduxmtdD New Cochrane Review looked at evidence from 11 studies: ❌ antibiotic azithromycin is not an effective treatment, 🤔not enough research on other types.
— The Cochrane Library (@CochraneLibrary) October 22, 2021
Podcast: Atopic Dermatitis Pearls.
27 Oct, 2021 | 01:01h | UTCAtopic Dermatitis Pearls – The Cribsiders
[Press release – not published yet] Moderna says its COVID vaccine produced a strong antibody response for kids 6 to 11.
26 Oct, 2021 | 02:06h | UTCPress release: Moderna Announces Positive Top Line Data from Phase 2/3 Study of COVID-19 Vaccine in Children 6 to 11 Years of Age
Commentary: Moderna says new data supports its COVID vaccine for kids 6 to 11 – NPR
Infection with Covid-19 carries a much higher risk of developing neurological complications than Covid-19 vaccines.
26 Oct, 2021 | 02:04h | UTCOriginal Study: Neurological complications after first dose of COVID-19 vaccines and SARS-CoV-2 infection – Nature Medicine
Commentaries:
Covid: Vaccine study links virus to rare neurological illness – BBC
Commentary on Twitter
A study in @NatureMedicine finds there is an increased risk of neurological complications in those who received COVID-19 vaccines, but the risk of these complications is greater following a positive SARS-CoV-2 test. https://t.co/WKnFa9InbL pic.twitter.com/xir6U3JhL8
— Nature Portfolio (@NaturePortfolio) October 25, 2021
What It Means To Be Fully Vaccinated.
26 Oct, 2021 | 01:57h | UTCWhat It Means To Be Fully Vaccinated – Think Global Health
Adult-Onset Type 1 Diabetes: Current Understanding and Challenges.
26 Oct, 2021 | 01:47h | UTCAdult-Onset Type 1 Diabetes: Current Understanding and Challenges – Diabetes Care
Related:
ADA Consensus Report: The Management of Type 1 Diabetes in Adults.
Guideline: ADA 2021 Standards of Medical Care in Diabetes
Association of a sweetened beverage tax with reduction in soda consumption in high school students.
26 Oct, 2021 | 01:30h | UTCAssociation of a Sweetened Beverage Tax With Soda Consumption in High School Students – JAMA Pediatrics (free for a limited period)
Related:
UK National Food Strategy: Tax sugar and salt and prescribe veg, report says.
Perspective – Sugar-sweetened beverage taxes: Lessons to date and the future of taxation
Cohort Study: Association Between Tax on Sugar Sweetened Beverages and Soft Drink Consumption
Meta-Analysis: Impact of Sugar‐sweetened Beverage Taxes on Purchases and Dietary Intake
Study: Snack Tax May be More Effective than a Sugary Drink Tax to Tackle Obesity
Sugar Tax: Why Health Experts Want it But Politicians and Industry are Resisting
The Effect of Food Price Changes on Consumer Purchases: A Randomized Experiment
Taxes on Sugar-Sweetened Beverages Associated with Reduced Consumption
Soda Tax Linked to a 50 Percent Reduction in Sugary Drink Consumption
Fiscal policies for diet and the prevention of noncommunicable diseases – World Health Organization
The Lancet taskforce on NCDs and economics
To improve global health, tax the things that are killing us – Financial Times
Reducing cardiovascular disease burden through targeted dietary policies
Fiscal policies for the prevention of diseases
Commentary on Twitter
Sweetened beverage consumption is higher among adolescents and young adults than any other age group. A new study at #jamapediatrics reports that sweetened beverage taxes are associated with reduced soda consumption in this group. https://t.co/UJdxpY7gl2 pic.twitter.com/aEdcUccLYW
— JAMA Pediatrics (@JAMAPediatrics) October 23, 2021
RCT: The association of Varenicline and Nicotine patch was not better than Varenicline alone to increase smoking abstinence; there was also no difference between 24-week vs. 12-week treatment courses in abstinence rates.
24 Oct, 2021 | 23:45h | UTCEffects of Combined Varenicline With Nicotine Patch and of Extended Treatment Duration on Smoking Cessation: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Is There a Role for Combined Use of Varenicline and Nicotine Patch or Extended Treatment Duration to Enhance Smoking Cessation? – JAMA (free for a limited period)
Commentary: Varenicline Combo, Extension No Better for Quitting Smoking – HealthDay
Commentary on Twitter
Study findings do not support the use of combined varenicline plus nicotine patch therapy (vs varenicline monotherapy) or of extended treatment duration (24 vs 12 weeks) for smoking cessation https://t.co/XcQMQZgQb9
— JAMA (@JAMA_current) October 19, 2021
Perspective | The flawed science of antibody testing for SARS-CoV-2 immunity.
22 Oct, 2021 | 10:30h | UTCThe Flawed Science of Antibody Testing for SARS-CoV-2 Immunity – JAMA
[Press release – not published yet] A phase 3 trial with more than 10,000 participants showed a booster dose of the Pfizer/BioNTech vaccine had an efficacy of 95.6% against disease; there were 5 cases in the booster group and 109 cases in the non-boosted group, not classified according to severity.
22 Oct, 2021 | 10:34h | UTC
Commentaries on Twitter
This will presumably mean everyone gets boosters early next year. That’s great, because they do work. Except it’s likely to be boosters for rich countries at the expense of primary vaccination for poorer countries. You won’t stop the pandemic when half the world is unvaccinated https://t.co/F31DMSI2zf
— Niall Conroy (@NICU_doc_salone) October 21, 2021
The 1st randomized trial of a booster (3rd) shot in 10,000 people, placebo-controlled, shows 95.6% efficacy, with 5 cases (Pfizer vaccine) vs 109 in placebo group, Delta variant, broad benefit across age groups https://t.co/TQpF35d8Jk pic.twitter.com/3RkqvXNfsU
— Eric Topol (@EricTopol) October 21, 2021
Cluster RCT: Increasing the dietary sources of calcium and protein (by providing additional milk, yogurt, and cheese) reduced hip fractures and falls in older adults in residential care.
22 Oct, 2021 | 10:21h | UTCNews release: Increasing dairy intake reduces falls and fractures among older care home residents – British Medical Journal
Commentary on Twitter
Increasing intake of foods rich in calcium and protein such as milk, yoghurt, and cheese, reduces falls and fractures in older adults living in residential care, finds a randomised controlled trial published @bmj_latest today https://t.co/QzozG4Odjb
— BMJ Group (@bmj_company) October 21, 2021
M-A: Risk factors for poor prognosis in children and adolescents with COVID-19.
22 Oct, 2021 | 10:24h | UTC
RCT: Mirtazapine not better than placebo for the treatment of agitation in people with dementia and was possibly associated with increased mortality (7 vs.1 deaths, difference not statistically significant; p=0·065).
22 Oct, 2021 | 10:19h | UTCCommentary: Common antidepressant should no longer be used to treat people with dementia – University of Exeter
Radiotherapy: Clinical pearls for primary care.
22 Oct, 2021 | 10:12h | UTCRadiotherapy: Clinical pearls for primary care – Canadian Family Physician
Podcast: Managing Pediatric Hypertension in Your Primary Care Clinic.
22 Oct, 2021 | 10:10h | UTC#36: Off the Cuff – Managing Pediatric Hypertension in Your Primary Care Clinic – The Cribsiders