Family Medicine
EuGMS Guidance: Management of post-acute COVID-19 patients in geriatric rehabilitation.
21 Nov, 2021 | 23:14h | UTCRelated:
Addressing Post-COVID Symptoms: A Guide for Primary Care Physicians.
Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the ‘long-haulers’.
Systematic Review: Short-term and long-term rates of postacute sequelae of SARS-CoV-2 infection.
WHO Consensus: A clinical case definition of post COVID-19 condition (Long Covid).
Characterizing long COVID: a living systematic review.
Long Covid – The illness narratives.
New guidelines to help doctors manage long COVID patients published.
M-A: More than 50 long-term effects of COVID-19. (several articles on the subject)
Estimation of SARS-CoV-2 infection fatality rate by age and comorbidity status using antibody screening of blood donors during the COVID-19 epidemic in Denmark – “The IFR was low for people younger than 51 years without comorbidity during the two waves (combined IFR = 3.36 per 100,000 infections)”.
21 Nov, 2021 | 23:12h | UTC
Commentary on Twitter
New in JID: A study in Denmark found that the SARS-CoV-2 infection fatality rate was low for people younger than 51 and otherwise healthy, increased with age and comorbidities, and declined from the 1st to the 2nd wave of the pandemic.
📄 https://t.co/lenryomRJ3 #IDSAJournals pic.twitter.com/TT8RefGjHw
— IDSA (@IDSAInfo) November 20, 2021
Consensus Statement: U.S. Multi-Society Task Force on Colorectal Cancer now suggests average-risk CRC screening begins at age 45.
21 Nov, 2021 | 23:01h | UTCRelated:
State of the Art Review: Screening and prevention of colorectal cancer.
USPSTF Statement: Start colorectal cancer screening at 45 years for most patients.
ACG Clinical Guidelines: Start colorectal cancer screening at 45
Overdiagnosis: it’s official – the term is now included in the medical subject headings (MeSH) vocabulary.
21 Nov, 2021 | 22:53h | UTCOverdiagnosis: it’s official – The BMJ
Related:
Overdiagnosis: what it is and what it isn’t – BMJ Evidence Based Medicine
Overdiagnosis across medical disciplines: a scoping review – The BMJ Open
Too much medical care: bad for you, bad for health care systems – STAT News
Screening: How overdiagnosis and other harms can undermine the benefits – Health News Review
Overdiagnosis: causes and consequences in primary health care – Canadian Family Physician
Five warning signs of overdiagnosis – The Conversation
What is overdiagnosed cancer? And why does it matter? – Croakey
Blame rising cancer overdiagnosis on ‘irrational exuberance’ for early detection – STAT
A food allergy epidemic… or just another case of overdiagnosis?
An epidemic of overdiagnosis: Melanoma diagnoses sky rocket
Editorial: COVID-19 vaccines for children – “Although it is true that most children experience asymptomatic or mild disease, some will get quite sick, and a small number will die. It’s why children are vaccinated against influenza, meningitis, chickenpox, and hepatitis”.
19 Nov, 2021 | 10:57h | UTCCOVID-19 vaccines for children – Science
Related: Review: Should children under 12 years of age be vaccinated against COVID-19?
Commentary on Twitter
"Although it is true that most children experience asymptomatic or mild COVID disease, some will get quite sick, and a small number will die.
It’s why children are vaccinated against influenza, meningitis, chickenpox, and hepatitis" @DrPaulOffit et al.https://t.co/mvXHXdiYha
— Madhu Pai, MD, PhD (@paimadhu) November 18, 2021
Global, regional, and national causes of under-5 mortality in 2000–19: an updated systematic analysis with implications for the Sustainable Development Goals.
19 Nov, 2021 | 10:40h | UTC
Commentary on Twitter
Progress is still needed to improve child health and end preventable deaths among children <5 years
New cause-specific estimates of infant mortality for 2000-19 are explored in this Article by Jamie Perin and colleagues @JohnsHopkinsSPH, @LSHTM & @WHO https://t.co/QJEDAd5jYT pic.twitter.com/Wis0v8YSav
— The Lancet Child & Adolescent Health (@LancetChildAdol) November 18, 2021
Pneumonia remains #1 postneonatal killer for children <5. Most deaths occur in children who live in poverty or humanitarian settings, have poor access to quality care, are malnourished & unimmunised. Many health centres don’t have antibiotics or O2. It’s 2021 not the Middle Ages. https://t.co/P7EhDN9KJ2
— Fiona Russell (@Fiona_M_Russell) November 18, 2021
What is the functional/organic distinction actually doing in psychiatry and neurology?
19 Nov, 2021 | 10:29h | UTC
Commentary on Twitter
Beautiful paper puts nails in coffin of outdated/inaccurate distinction "Functional" Vs "Organic".
Confusion causes great harms:
I've seen many 100s patients mislabeled primary psych disorder whose symptoms were really caused by medical illness/med side effect/drugs.Must read: https://t.co/Fl492ADrjE
— Allen Frances (@AllenFrancesMD) November 12, 2021
M-A: Effectiveness of public health measures in reducing the incidence of covid-19, SARS-CoV-2 transmission, and covid-19 mortality.
18 Nov, 2021 | 08:59h | UTC
Commentary on Twitter
Experts call for continued use of personal protective and social measures alongside covid-19 vaccination in @bmj_latest today https://t.co/MOT4O2R6Ui pic.twitter.com/dAxhStSxpJ
— BMJ Group (@bmj_company) November 18, 2021
Review: Should children under 12 years of age be vaccinated against COVID-19?
18 Nov, 2021 | 08:56h | UTCShould children be vaccinated against COVID-19? – Archives of Disease in Childhood
Commentary from the author on Twitter (thread – click for more)
Should #children be vaccinated against #COVID19?
Our review outlines the points to consider in weighing up whether all healthy children under 12y should be vaccinated against COVID-19.https://t.co/JtoOr2TZoq#medpeds #IDTwitter #PaedsID #tweetiatrician #paediatrics
🧵1/n pic.twitter.com/g4UGu3pMsE
— Nigel Curtis (@nigeltwitt) November 6, 2021
Covid: Children in UK told to delay jab for 12 weeks after infection.
18 Nov, 2021 | 08:54h | UTCCovid: Children told to delay jab for 12 weeks after infection – BBC
Original Report: Joint Committee on Vaccination and Immunisation (JCVI) advice on COVID-19 vaccination in people aged 16 to 17 years: 15 November 2021
[Preprint] M-A: Inhaled corticosteroids in COVID-19 outpatients.
18 Nov, 2021 | 08:48h | UTCInhaled Corticosteroids for Outpatients with Covid-19: A Meta-Analysis – medRxiv
Commentary: Favourable meta-analysis of inhaled corticosteroids in COVID-19 outpatients – News Medical
Related:
Position Paper: Recommendations for the use of topical inhalant budesonide in COVID-19.
RCT: Inhaled budesonide shortens recovery time in non-hospitalized patients with COVID-19
Phase 2 RCT: Inhaled budesonide shows promise for the treatment of early COVID-19
Commentary on Twitter
The first meta-analysis of the 4 completed & reported trials of outpatient inhaled corticosteroid #COVID19 treatment
The results support the use of inhaled corticosteroids (ciclesonide or budesonide) for the resolution of symptoms at day 14 of treatmenthttps://t.co/KnBDKhfYmi pic.twitter.com/WSd9htXwe4— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) November 5, 2021
Observational study found monitoring outpatients with Covid-19 using text messages that allowed the report of worsening symptoms was associated with improved outcomes.
17 Nov, 2021 | 08:53h | UTCNews Release: Automated Texting System Saved Lives Weekly During First COVID Surge – Penn Medicine
Commentaries:
Monitoring outpatients by text appeared to reduce mortality from COVID-19 – ACP Internist
Texting saved lives during Covid. What does that mean for health care’s future? – STAT
Commentary from the author on Twitter (thread – click for more)
1/ For the >80,000 people in the U.S who will test positive for #Covid19 today, what can we offer to support access to care but help them safely remain at home?
Our team is excited to finally share important, new findings out today in @AnnalsofIM
👉https://t.co/VOtpucwWGD pic.twitter.com/UbNRP5bnW4— M. Kit Delgado, MD, MS (@kit_delgadoMD) November 16, 2021
The big questions about Covid-19 booster shots – “From the why to the who, we still need a lot of answers about booster shots”.
17 Nov, 2021 | 08:48h | UTCThe big questions about Covid-19 booster shots – Vox
Commentary on Twitter
1/ Thoughtful piece by @voxdotcom's @germanrlopez on COVID vaccine boosters.
In good company with @ashishkjha @DrPaulOffit @MonicaGandhi9 @jenkatesdc.https://t.co/pOwZLkmJHn pic.twitter.com/ZAD7AOj0Vz
— Céline Gounder, MD, ScM, FIDSA 🇺🇦 (@celinegounder) November 12, 2021
AAN Guideline: Dopaminergic Therapy for Motor Symptoms in Early Parkinson Disease.
17 Nov, 2021 | 08:32h | UTCNews Release: AAN Issues Guideline for Treatment of Early Parkinson’s Disease – American Academy of Neurology
Addressing Post-COVID Symptoms: A Guide for Primary Care Physicians.
17 Nov, 2021 | 08:42h | UTCRelated:
Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the ‘long-haulers’.
Systematic Review: Short-term and long-term rates of postacute sequelae of SARS-CoV-2 infection.
WHO Consensus: A clinical case definition of post COVID-19 condition (Long Covid).
Characterizing long COVID: a living systematic review.
Long Covid – The illness narratives.
New guidelines to help doctors manage long COVID patients published.
M-A: More than 50 long-term effects of COVID-19. (several articles on the subject)
Individual participant data meta-analysis of major randomized trials showed that treatment of hypertension with ACEIs or ARBs reduced the risk of new-onset type 2 diabetes compared to other drugs.
17 Nov, 2021 | 08:29h | UTCCommentaries:
Blood pressure drugs could prevent type 2 diabetes, study finds – The Guardian
Position Statement: Preoperative Care for Cataract Surgery – “In spite of evidence debunking the utility of testing before cataract surgery, studies suggest that medical testing and the use of medical consultations before cataract surgery continue to increase”.
17 Nov, 2021 | 08:33h | UTC
Commentary on Twitter
Nicely written position paper on preop care for cataract surgery. Addresses the most frequent questions (although actual study data is limited). Basically no tests, continue meds, and proceed in most cases unless recent MI,PCI,VTE,CVA,DKA, or HTN urgency. https://t.co/PLHm1LjhZg
— Steven Cohn, MD (@preopconsult) November 16, 2021
Randomized, crossover clinical trial: In patients with heart failure with preserved ejection fraction and chronotropic incompetence, betablocker withdrawal improved maximal functional capacity.
17 Nov, 2021 | 08:27h | UTCCommentary: Peak VO2 Improved After Beta-Blocker Withdrawal in Some HFpEF Patients: Beta-blockers may not benefit HFpEF patients with chronotropic incompetence – MedPage Today (free registration required)
Long-term follow up of randomized trials found that children who were given nutrient or supplement enriched formula milk as babies didn’t have higher academic performances as adolescents.
17 Nov, 2021 | 08:14h | UTCNews release: Study finds no benefit of enriched formula milks on later academic performance – British Medical Journal
Editorial: Enriched formula milks and academic performance in later childhood – The BMJ
Commentary on Twitter
https://twitter.com/bmj_company/status/1458691047933026307
Real-world ethics in palliative care: A systematic review of the ethical challenges reported by specialist palliative care practitioners in their clinical practice.
17 Nov, 2021 | 08:18h | UTC
Commentary on Twitter
The range of ethical challenges faced by specialist palliative care practitioners exceeds the breadth of those detailed in palliative care textbooks and ethics resources. #hpm #hapc https://t.co/pvwkYrJmIo pic.twitter.com/qb5803oQg1
— Palliative Medicine (@PalliativeMedJ) March 3, 2021
Drug-induced orthostatic hypotension: A systematic review and meta-analysis of randomized controlled trials.
17 Nov, 2021 | 08:12h | UTC
Pfizer’s pill is the latest COVID treatment to show promise. Here are some more.
16 Nov, 2021 | 08:41h | UTCPfizer’s pill is the latest COVID treatment to show promise. Here are some more – The Conversation
Related:
The U.K. approves Merck’s COVID-19 antiviral pill, calling it a world first.
Merck to allow other nations to produce new COVID-19 antiviral.
Video: Merck’s Covid pill could transform treatment. Here’s how it works.
How antiviral pill Molnupiravir shot ahead in the COVID drug hunt.
What we know — and don’t know — about Merck’s new Covid-19 pill.
Merck’s Covid-19 pill is great news but may not be a game-changer.
Video | A Pill For COVID? A Doctor Explains Molnupiravir.
Merck v Pfizer: here’s how the two new COVID antiviral drugs work and will be used.
16 Nov, 2021 | 08:39h | UTCRelated:
The U.K. approves Merck’s COVID-19 antiviral pill, calling it a world first.
Merck to allow other nations to produce new COVID-19 antiviral.
Video: Merck’s Covid pill could transform treatment. Here’s how it works.
How antiviral pill Molnupiravir shot ahead in the COVID drug hunt.
What we know — and don’t know — about Merck’s new Covid-19 pill.
Merck’s Covid-19 pill is great news but may not be a game-changer.
Video | A Pill For COVID? A Doctor Explains Molnupiravir.
#AHA21 – [News release – not published yet] RCT: Long-term, low-dose aspirin did not affect risk of dementia in adults with type 2 diabetes.
16 Nov, 2021 | 08:30h | UTCOriginal Study: Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes
#AHA21 – Among patients with intermittent atrial fibrillation, n-of-1 trials with 466 patients found alcohol, but not caffeine, increased the risk of atrial fibrillation events.
16 Nov, 2021 | 08:29h | UTCIndividualized Studies of Triggers of Paroxysmal Atrial Fibrillation: The I-STOP-AFib Randomized Clinical Trial – JAMA Cardiology (free for a limited period)
Commentary: Avoiding AF Triggers Doesn’t Improve Quality of Life: I-STOP-AFib – TCTMD
Commentary on Twitter
Study found randomization to N-of-1 trial #Afib trigger testing fails to improve QOL but reduces number of Afib episodes. Testing alcohol associated with more Afib, but caffeine is not https://t.co/LElYEBUEcs
— JAMA Cardiology (@JAMACardio) November 14, 2021