#AHA21 – Among patients with intermittent atrial fibrillation, n-of-1 trials with 466 patients found alcohol, but not caffeine, increased the risk of atrial fibrillation events.

Individualized Studies of Triggers of Paroxysmal Atrial Fibrillation: The I-STOP-AFib Randomized Clinical Trial – JAMA Cardiology (free for a limited period)

Commentary: Avoiding AF Triggers Doesn’t Improve Quality of Life: I-STOP-AFib – TCTMD

Commentary on Twitter

Study found randomization to N-of-1 trial #Afib trigger testing fails to improve QOL but reduces number of Afib episodes. Testing alcohol associated with more Afib, but caffeine is not https://t.co/LElYEBUEcs

— JAMA Cardiology (@JAMACardio) November 14, 2021