Family Medicine
The COVID generation: how is the pandemic affecting kids’ brains?
13 Jan, 2022 | 08:53h | UTCThe COVID generation: how is the pandemic affecting kids’ brains? – Nature
A clinical case definition of post-COVID-19 condition by a Delphi consensus.
13 Jan, 2022 | 08:45h | UTC
Commentary on Twitter
New Review: A clinical case definition of post-#COVID19 condition by a Delphi consensus https://t.co/AoWBgCeMq5 pic.twitter.com/kAW1YY6kgr
— The Lancet Infectious Diseases (@TheLancetInfDis) December 22, 2021
Review: Diagnosis and treatment of sexually transmitted infections.
13 Jan, 2022 | 08:38h | UTCDiagnosis and Treatment of Sexually Transmitted Infections: A Review – JAMA (free for a limited period)
The year in cardiovascular medicine 2021: diabetes and metabolic disorders.
13 Jan, 2022 | 08:33h | UTCThe year in cardiovascular medicine 2021: diabetes and metabolic disorders – European Heart Journal
The year in cardiovascular medicine 2021: dyslipidemia.
13 Jan, 2022 | 08:30h | UTCThe year in cardiovascular medicine 2021: dyslipidemia – European Heart Journal
M-A: Intermittent Fasting and Obesity-Related Health Outcomes.
13 Jan, 2022 | 08:22h | UTC
Cohort Study: In preterm premature rupture of membranes at 24-31 weeks, antibiotic prophylaxis based on third-generation cephalosporin may be associated with improved perinatal outcomes compared to amoxicillin.
13 Jan, 2022 | 08:10h | UTCAntibiotic prophylaxis in preterm premature rupture of membranes at 24-31 weeks’ gestation: perinatal and 2-year outcomes in the EPIPAGE-2 cohort – BJOG (link to abstract – $ for full-text)
International study identifies predictors of severe outcomes in children with COVID-19.
12 Jan, 2022 | 09:05h | UTCNews Release: International study identifies predictors of severe outcomes in children with COVID-19 – University of Calgary
Original Study: Outcomes of SARS-CoV-2–Positive Youths Tested in Emergency Departments: The Global PERN–COVID-19 Study – JAMA Network Open
Statement on potential drug-drug interactions between Ritonavir-boosted Nirmatrelvir (Paxlovid) and concomitant medications; antiarrhythmics, oral anticoagulants, immunosuppressants, anticonvulsants, antineoplastics, and neuropsychiatric drugs are among the drugs of concern.
12 Jan, 2022 | 09:09h | UTCCommentaries:
Pfizer antiviral pills may be risky with other medications – NBC News
See also: What’s New in the Guidelines – NIH COVID-19 Treatment Guidelines
Podcast: Long COVID Pearls.
12 Jan, 2022 | 09:04h | UTC#315 Long COVID with Dr. Monica Verduzco-Gutierrez – The Curbsiders
RCT: Endoscopic sinus surgery with medical therapy vs. medical therapy alone for chronic rhinosinusitis with nasal polyps.
12 Jan, 2022 | 08:51h | UTCEndoscopic sinus surgery with medical therapy versus medical therapy for chronic rhinosinusitis with nasal polyps: a multicentre, randomised, controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary on Twitter
NEW Research—Endoscopic sinus surgery + medical therapy > medical therapy alone in pts w/ chronic rhinosinusitis w/ nasal polyps (although minimal clinically important difference was not met)
From Wytske Fokkens & colleagues https://t.co/VKxCQZ97Am pic.twitter.com/IzXq712lNL
— The Lancet Respiratory Medicine (@LancetRespirMed) January 8, 2022
RCT: Among patients younger than 21 years of age with provoked thromboembolism, anticoagulation for 6 weeks was non-inferior vs. 12 weeks on the risk of recurrence and bleeding events.
12 Jan, 2022 | 08:53h | UTCEffect of Anticoagulant Therapy for 6 Weeks vs 3 Months on Recurrence and Bleeding Events in Patients Younger Than 21 Years of Age With Provoked Venous Thromboembolism: The Kids-DOTT Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Duration of Anticoagulant Treatment for Acute Provoked Venous Thromboembolism in Pediatric Patients – JAMA (free for a limited period)
Cohort Study: Higher consumption of olive oil linked to lower risk of cardiovascular, cancer, and all-cause mortality.
12 Jan, 2022 | 08:41h | UTCConsumption of Olive Oil and Risk of Total and Cause-Specific Mortality Among U.S. Adults – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries:
Higher olive oil intake associated with lower risk of CVD mortality – American College of Cardiology
Consequences of a diagnostic label: A systematic scoping review and thematic framework.
12 Jan, 2022 | 08:37h | UTC
AHA Scientific Statement: Comprehensive management of cardiovascular risk factors for adults with Type 2 Diabetes.
11 Jan, 2022 | 02:40h | UTC
Medical Decisions: Some are Easy and Some Not So Much.
11 Jan, 2022 | 02:31h | UTCMedical Decisions: Some are Easy and Some Not So Much – Stop and Think blog, by John Mandrola
Commentary on Twitter
Preventive therapy reduces the probability of a negative outcome. There are 2 big snags with preventive therapy:
1. All medical interventions come with the potential for harm.
2. Preventive therapies have modest effect sizes.
great read by @drjohnm https://t.co/Hk8VPnUv3m— Tjasa Zajc (@zajctjasa) January 9, 2022
Systematic Review: The effectiveness and safety of treatments for recurrent vulvovaginal candidiasis.
11 Jan, 2022 | 02:24h | UTCTreatment for recurrent vulvovaginal candidiasis (thrush) – Cochrane Library
The ‘Ten Commandments’ of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure.
11 Jan, 2022 | 02:20h | UTCRelated:
NICE Guideline | Acute heart failure: diagnosis and management.
The ‘ten commandments’ for the 2021 ESC Guidelines on CVD prevention.
M-A: Fecal immunochemical test to triage patients with possible colorectal cancer symptoms.
11 Jan, 2022 | 02:18h | UTC
Commentary on Twitter
?#CuttingEdgeBlog Plain English summary?
"Worried about symptoms of bowel cancer? A simple stool test may help."@ian_bissett @SawKS88 @ChenLiu_NZ @williamxu_98 @chrisvarghese98
Blog?: https://t.co/Pb7zfsfWT3
Based on the paper ?: https://t.co/20proTApNd pic.twitter.com/IAUsHIqUrn
— BJS (@BJSurgery) January 10, 2022
Cohort Study: Ciprofloxacin exposure during pregnancy was not associated with miscarriage or major malformations in a nationwide study from Denmark.
11 Jan, 2022 | 02:08h | UTCCiprofloxacin exposure and adverse pregnancy outcomes: a Danish nationwide cohort study – BJOG (link to abstract – $ for full-text)
Cohort study: Among health care workers previously vaccinated with 2 doses of the Pfizer-BioNTech vaccine, receiving a third dose was associated with reduced risk of SARS-CoV-2 infection.
11 Jan, 2022 | 01:35h | UTCEditorial: Booster Vaccination to Reduce SARS-CoV-2 Transmission and Infection – JAMA
Review: Rapid diagnostic testing for SARS-CoV-2.
11 Jan, 2022 | 01:34h | UTCRapid Diagnostic Testing for SARS-CoV-2 – New England Journal of Medicine
M-A: Fatigue and cognitive impairment in Post-COVID-19 Syndrome.
11 Jan, 2022 | 01:28h | UTC
CDC Report: COVID-19 vaccine safety in children aged 5–11 Years.
9 Jan, 2022 | 01:09h | UTCCommentary: COVID-19 vaccine appears safe in children aged 5–11 Years – News Medical
Commentary on Twitter
Early vaccine safety data for children ages 5–11 years old found that reactions such as fatigue and headaches were commonly reported following Pfizer-BioNTech #COVID19 vaccine. Everyone ages 5 years & older should get vaccinated as soon as possible. https://t.co/D66QgLRWni pic.twitter.com/8I48L5GmcG
— MMWR (@CDCMMWR) December 30, 2021
New CDC Guidance shortens isolation and quarantine period for Covid-19; patients that tested positive should isolate for 5 days and, if asymptomatic after this period, can leave isolation if they can continue to mask for 5 days to minimize the risk of infecting others.
9 Jan, 2022 | 01:13h | UTCSee also: Quarantine and Isolation – Centers for Disease Control and Prevention
Commentaries:
Facing criticism, CDC updates Covid-19 isolation recommendations with guidance on testing – CNN
CDC posts rationale for shorter isolation, quarantine – Associated Press
Covid-19: CDC shortens isolation period as US cases hit record high – The BMJ
Shortened CDC COVID isolation guide draws sharply mixed reviews – CIDRAP
New CDC isolation guidelines raise concerns among health experts – NPR
CDC Reduces Recommended Isolation Time for People With COVID-19 – HealthDay
COVID isolation and quarantine period for general population shortened by CDC – News Medical
CDC shortens recommended Covid-19 isolation and quarantine time – CNN
CDC cuts the recommended isolation and quarantine periods for coronavirus infections – NPR
US officials recommend shorter COVID isolation, quarantine – Associated Press
See new recommendations from other countries:
Covid: Self-isolation cut from 10 days to seven with negative tests – BBC