Evidence-based Medicine

The path forward for ChatGPT in academia – Lumo’s Newsletter

Nonhuman “Authors” and Implications for the Integrity of Scientific Publication and Medical Knowledge – JAMA

Tools such as ChatGPT threaten transparent science; here are our ground rules for their use – Nature

ChatGPT listed as author on research papers: many scientists disapprove – Nature

Methodology and Design of Platform Trials: A meta-epidemiological study – Journal of Clinical Epidemiology

Methodology and Design of Platform Trials | A meta-epidemiological study

31 Mar, 2023 | 13:22h | UTC

Platform Trials — Beware the Noncomparable Control Group – New England Journal of Medicine

Opinion | ChatGPT will change Medicine

30 Mar, 2023 | 14:22h | UTC

Chat GPT will change Medicine – Vinay Prasad’s Observations and Thoughts

ChatGPT vs. NCI: analyzing the quality of cancer information on myths and misconceptions

ChatGPT has many uses. Experts explore what this means for healthcare and medical research – The Conversation

Artificial Intelligence in Medicine & ChatGPT: De-Tether the Physician – Journal of Medical Systems (if the link is paywalled, try this one)

Can artificial intelligence help for scientific writing? – Critical Care

Artificial intelligence in academic writing: a paradigm-shifting technological advance

Performance of ChatGPT on USMLE: potential for AI-assisted medical education using large language models

Perspective | ChatGPT-assisted diagnosis: is the future suddenly here?

Perspective | Generating scholarly content with ChatGPT: ethical challenges for medical publishing

ChatGPT: Will It Transform the World of Health Care? – UCSF Department of Medicine

ChatGPT and the future of medical writing (ChatGPT itself wrote this paper)

The path forward for ChatGPT in academia – Lumo’s Newsletter

Nonhuman “Authors” and Implications for the Integrity of Scientific Publication and Medical Knowledge – JAMA

Tools such as ChatGPT threaten transparent science; here are our ground rules for their use – Nature

ChatGPT listed as author on research papers: many scientists disapprove – Nature

Trends of Randomized Clinical Trials Citing Prior Systematic Reviews, 2007-2021 – JAMA Network Open

Trends of randomized clinical trials citing prior systematic reviews, 2007-2021

27 Mar, 2023 | 12:56h | UTC

Invited Commentary: Should a Systematic Review Be Required in a Clinical Trial Report? Perhaps, But Not Yet – JAMA Network Open

Commentary on Twitter

The percentage of RCTs citing systematic reviews increased from 36% in 2007-8 to 72% since 2020. RCTs with ≥100 participants, nonindustry funders, and authors from high-income countries were more likely to cite systematic reviews. https://t.co/rMN7eEmkqD

— JAMA Network Open (@JAMANetworkOpen) March 23, 2023

Opinion | The rapid growth of mega-journals: threats and opportunities

22 Mar, 2023 | 13:40h | UTC

The Rapid Growth of Mega-Journals: Threats and Opportunities – JAMA (free for a limited period)

Opinion | Irreconcilable differences: the divorce between response rates, progression-free survival, and overall survival

20 Mar, 2023 | 13:45h | UTC

Irreconcilable Differences: The Divorce Between Response Rates, Progression-Free Survival, and Overall Survival – Journal of Clinical Oncology

Methods Primer | Non-linear predictor outcome associations

17 Mar, 2023 | 12:52h | UTC

Non-linear predictor outcome associations – BMJ Medicine

Proposed triggers for retiring a living systematic review

15 Mar, 2023 | 15:02h | UTC

Proposed triggers for retiring a living systematic review – BMJ Evidence-Based Medicine

Video | Tutorial explores ways of analyzing data from RCTs, including intention-to-treat, per-protocol, and as-treated analyses

14 Mar, 2023 | 13:53h | UTC

Good Intentions to Treat – NEJM Evidence

SR | Do treatment effects in randomized trials differ when using active placebo compared to standard placebo?

14 Mar, 2023 | 13:25h | UTC

Impact of active placebo controls on estimated drug effects in randomised trials: a systematic review of trials with both active placebo and standard placebo – Cochrane Library

Summary: Do treatment effects in randomised trials differ when using active placebo compared to standard placebo? – Cochrane Library

Commentary on Twitter

🧵 In our recent #Cochrane Review, we look at the impact of using #ActivePlacebo control versus standard placebo in randomised drug trials. https://t.co/7VwTOSRKxF #Blinding #Unblinding #Placebo #Bias @cochranemthds @AsgerPaludan @ChrisPaWer

1/10

— David Laursen (@LaursenDavid) March 8, 2023

Perspective | How to not be completely wrong about masks

8 Mar, 2023 | 14:25h | UTC

How to not be completely wrong about masks – The Munro Report

Let’s Do the Cochrane Review of Physical Measures to Reduce the Spread of Viruses – Sensible Medicine

Hospital masking should be optional – Sensible Medicine

Face masks to prevent transmission of respiratory infections: Systematic review and meta-analysis of randomized controlled trials on face mask use – PLOS One

RCT | Medical masks vs. N95 respirators for preventing COVID-19 among health care workers.

Science, Competing Values, and Trade-offs in Public Health — The Example of Covid-19 and Masking – New England Journal of Medicine

Commentary on Twitter

Excellent and sensible interpretation of the data, on both ends of the spectrum, and everything in between.

(Will forgive the split infinitive in the title. 😉)

How to not be completely wrong about masks, by @apsmunro https://t.co/85Ot6oUOZF

— Paul Sax (@PaulSaxMD) March 2, 2023

Perspective | Artificial intelligence in medicine & ChatGPT: de-tether the physician

7 Mar, 2023 | 13:10h | UTC

Artificial Intelligence in Medicine & ChatGPT: De-Tether the Physician – Journal of Medical Systems (if the link is paywalled, try this one)

Can artificial intelligence help for scientific writing? – Critical Care

Artificial intelligence in academic writing: a paradigm-shifting technological advance

Performance of ChatGPT on USMLE: potential for AI-assisted medical education using large language models

Perspective | ChatGPT-assisted diagnosis: is the future suddenly here?

Perspective | Generating scholarly content with ChatGPT: ethical challenges for medical publishing

ChatGPT: Will It Transform the World of Health Care? – UCSF Department of Medicine

ChatGPT and the future of medical writing (ChatGPT itself wrote this paper)

The path forward for ChatGPT in academia – Lumo’s Newsletter

Nonhuman “Authors” and Implications for the Integrity of Scientific Publication and Medical Knowledge – JAMA

Tools such as ChatGPT threaten transparent science; here are our ground rules for their use – Nature

ChatGPT listed as author on research papers: many scientists disapprove – Nature

ChatGPT has many uses. Experts explore what this means for healthcare and medical research – The Conversation

ChatGPT has many uses. Experts explore what this means for healthcare and medical research

7 Mar, 2023 | 13:11h | UTC

Can artificial intelligence help for scientific writing? – Critical Care

Artificial intelligence in academic writing: a paradigm-shifting technological advance

Performance of ChatGPT on USMLE: potential for AI-assisted medical education using large language models

Perspective | ChatGPT-assisted diagnosis: is the future suddenly here?

Perspective | Generating scholarly content with ChatGPT: ethical challenges for medical publishing

ChatGPT: Will It Transform the World of Health Care? – UCSF Department of Medicine

ChatGPT and the future of medical writing (ChatGPT itself wrote this paper)

The path forward for ChatGPT in academia – Lumo’s Newsletter

Nonhuman “Authors” and Implications for the Integrity of Scientific Publication and Medical Knowledge – JAMA

Tools such as ChatGPT threaten transparent science; here are our ground rules for their use – Nature

ChatGPT listed as author on research papers: many scientists disapprove – Nature

Registry randomised trials: a methodological perspective – BMJ Open

Registry randomized trials: a methodological perspective

6 Mar, 2023 | 14:00h | UTC

Opinion | There is no such thing as a validated prediction model

1 Mar, 2023 | 13:57h | UTC

There is no such thing as a validated prediction model – BMC Medicine

Is a one-size-fits-all ‘12-month rule’ appropriate when it comes to the last search date in systematic reviews?

1 Mar, 2023 | 13:48h | UTC

Is a one-size-fits-all ‘12-month rule’ appropriate when it comes to the last search date in systematic reviews? – BMJ Evidence-Based Medicine

Commentary on Twitter

Is a one-size-fits-all ‘12-month rule’ appropriate when it comes to the last search date in systematic reviews?

Analysis by @gillianstokesm @EPPICentre @KatySutcliffe @UCLSocRes @James_M_Thomas #OpenAccess

Link: https://t.co/aNAdDXgphn pic.twitter.com/f2JZiaVDtz

— BMJ Evidence-Based Medicine (@BMJ_EBM) January 17, 2023

Perspective | The inertia of clinical trials and unethical control arms in oncology

28 Feb, 2023 | 13:51h | UTC

The inertia of clinical trials and unethical control arms – Sensible Medicine

Unique considerations for patient retention in decentralized clinical trials

28 Feb, 2023 | 13:43h | UTC

Unique Considerations for Patient Retention in Decentralized Clinical Trials – The Association of Clinical Research Professionals

Analysis of rates of completion, delays, and participant recruitment in randomized clinical trials in surgery

28 Feb, 2023 | 13:25h | UTC

Analysis of Rates of Completion, Delays, and Participant Recruitment in Randomized Clinical Trials in Surgery – JAMA Network Open

Commentary on Twitter

Fewer than one-in-six surgical RCTs registered on https://t.co/FRe6v3XZPP successfully recruit their target sample size within their planned timeframe. https://t.co/hZLH0LTDpq

— JAMA Network Open (@JAMANetworkOpen) January 17, 2023

Perspective | Beware of overdiagnosis harms from screening, lower diagnostic thresholds, and incidentalomas

27 Feb, 2023 | 13:18h | UTC

Summary: This article discusses the concept of overdiagnosis and its relevance to clinical practice guidelines. Overdiagnosis is the diagnosis of a condition that, if unrecognized, would not result in symptoms or cause a patient harm during their lifetime, such as discovering a low-grade cancer that will never lead to symptoms at the end of life. But, unlike false positives, overdiagnosed individuals truly have the condition; they just don’t benefit from the diagnosis. Overdiagnosis can also result from lowering diagnostic thresholds for diagnosing a disease, which inflates diagnosis rates among patients and leads to recommendations for subsequent interventions without clear benefits. The article highlights the importance of providing accurate information to patients about the possibility and burden of overdiagnosis to inform shared decision-making and minimize the harms of screening interventions.

Article: Beware of overdiagnosis harms from screening, lower diagnostic thresholds, and incidentalomas – Canadian Family Physician

Broadening risk factor or disease definition as a driver for overdiagnosis: A narrative review – Journal of Internal Medicine

Overdiagnosis: it’s official – The BMJ

Overdiagnosis: what it is and what it isn’t – BMJ Evidence Based Medicine

Overdiagnosis across medical disciplines: a scoping review – The BMJ Open

Too much medical care: bad for you, bad for health care systems – STAT News

Overdiagnosis: causes and consequences in primary health care – Canadian Family Physician

Five warning signs of overdiagnosis – The Conversation

What is overdiagnosed cancer? And why does it matter? – Croakey

Blame rising cancer overdiagnosis on ‘irrational exuberance’ for early detection – STAT

Preventing overdiagnosis and the harms of too much sport and exercise medicine – British Journal of Sports Medicine

Study shows that current definitions of chronic kidney disease overestimate the CKD burden in older individuals and results in overdiagnosis.

Opinion | More kids are being diagnosed with ADHD for borderline (yet challenging) behaviors. Our new research shows why that’s a worry

A food allergy epidemic… or just another case of overdiagnosis?

An epidemic of overdiagnosis: Melanoma diagnoses sky rocket

Perspective | Can artificial intelligence help for scientific writing?

27 Feb, 2023 | 13:09h | UTC

Can artificial intelligence help for scientific writing? – Critical Care

Perspective | ChatGPT-assisted diagnosis: is the future suddenly here?

Perspective | Generating scholarly content with ChatGPT: ethical challenges for medical publishing

ChatGPT: Will It Transform the World of Health Care? – UCSF Department of Medicine

ChatGPT and the future of medical writing (ChatGPT itself wrote this paper)

The path forward for ChatGPT in academia – Lumo’s Newsletter

Nonhuman “Authors” and Implications for the Integrity of Scientific Publication and Medical Knowledge – JAMA

Tools such as ChatGPT threaten transparent science; here are our ground rules for their use – Nature

ChatGPT listed as author on research papers: many scientists disapprove – Nature