Endocrinology (all articles)
Overt and Subclinical Hypothyroidism in the Elderly: When to Treat?
12 Apr, 2019 | 01:26h | UTCOvert and Subclinical Hypothyroidism in the Elderly: When to Treat? – Frontiers in Endocrinology (free)
Related: Hypothyroidism in the Elderly: Who Should Be Treated and How? (free) AND Meta-Analysis: Treating Subclinical Hypothyroidism is Not Associated with Quality of Life and Thyroid-Related Symptoms (free) AND Review: Pitfalls on the Replacement Therapy for Hypothyroidism (free) AND Subclinical Hypothyroidism: When to Treat (free) AND Randomized Trial: Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism (free study and commentary)
Cohort Study: 5α-reductase Inhibitors Linked to Increased Risk of Type 2 Diabetes
11 Apr, 2019 | 00:34h | UTCCommentary: Reducing the risk of type 2 diabetes in men with benign prostatic hyperplasia—old steroids, new tricks – The BMJ Opinion (free)
JAMA Guideline Synopsis: 2018 AHA/ACC Guideline on the Management of Blood Cholesterol: Primary Prevention
11 Apr, 2019 | 00:33h | UTCGuideline Synopsis: 2018 American Heart Association / American College of Cardiology Multisociety Guideline on the Management of Blood Cholesterol: Primary Prevention – JAMA Cardiology (free for a limited period)
Four Cases of Cholesterol Management Informed by the 2018 AHA/ACC Guideline on the Management of Blood Cholesterol
11 Apr, 2019 | 00:31h | UTCFour Cases of Cholesterol Management Informed by the 2018 American Heart Association / American College of Cardiology Multisociety Guideline on the Management of Blood Cholesterol – JAMA Cardiology (free for a limited period)
Case Report: Use of Vitamin D Drops Leading to Kidney Failure in a 54-year-old Man
9 Apr, 2019 | 02:07h | UTC“Vitamin D toxicity is rare, but clinicians must be aware of the risks of vitamin D use to limit complications related to hypercalcemia”.
Guideline: Surgical Therapy of Adrenal Tumors
4 Apr, 2019 | 22:46h | UTC
Randomized Trial: Insulin Pump vs. Multiple Daily Injection for Type 1 Diabetes
4 Apr, 2019 | 22:25h | UTCCommentaries: What is the most effective way to deliver subcutaneous insulin—pumps or injections? – The BMJ Opinion (free) AND Randomized trial questions superiority of insulin pumps over injections in children – MedWire News (free)
Related: Insulin pumps not much better than multiple injections for intensive control of type 1 diabetes (free study and commentary)
Randomized Trial: Automated Insulin Dosing Guidance to Optimize Insulin Management in Type 2 Diabetes
4 Apr, 2019 | 22:12h | UTCAutomated insulin dosing guidance to optimise insulin management in patients with type 2 diabetes: a multicentre, randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Promoting Better Glucose Management for Type 2 Diabetes – NEJM Journal Watch (free for a limited period) AND Automated insulin system improves glycemic control – MedicalXpress (free)
Executive Summary of the DAROC Clinical Practice Guidelines for Diabetes Care
4 Apr, 2019 | 12:37h | UTCRelated Guidelines: ADA 2019 Standards of Medical Care in Diabetes (free supplement) AND AACE/ACE Comprehensive Type 2 Diabetes Management Algorithm 2019 – Endocrine Practice (Free PDF and Slide Presentations) AND Diabetes Canada 2018 clinical practice guidelines for the prevention and management of diabetes in Canada (free) AND 2019 Guidelines on the management of diabetic patients. A position of Diabetes Poland – Clinical Diabetology (free PDF) AND Treatment of Diabetes in Older Adults: An Endocrine Society* Clinical Practice Guideline – The Journal of Clinical Endocrinology & Metabolism(free PDF)
Randomized Trial: Metformin to Treat Pregnant Women with Polycystic Ovary Syndrome
4 Apr, 2019 | 22:11h | UTCUse of metformin to treat pregnant women with polycystic ovary syndrome (PregMet2): a randomised, double-blind, placebo-controlled trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentary: Well-known drug has less risk for preterm delivery in PCOS – Norwegian University of Science and Technology (free)
Study: Long-term Effects of Metformin on Diabetes Prevention
4 Apr, 2019 | 01:41h | UTCLong-term Effects of Metformin on Diabetes Prevention: Identification of Subgroups That Benefited Most in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study – Diabetes Care (free for a limited period)
Commentaries: Safe and Cheap Metformin Prevents Type 2 Diabetes Over 15 Years – Medscape (free registration required) AND Long-term metformin offsets diabetes in patients with higher glucose/HbA1c, history of gestational diabetes – MDedge (free)
Italian Consensus for the Classification and Reporting of Thyroid Cytology: The Risk of Malignancy Between Indeterminate Lesions at Low or High Risk
30 Mar, 2019 | 17:55h | UTC
Review: Management of hypothalamic disease in patients with craniopharyngioma
30 Mar, 2019 | 17:31h | UTCManagement of hypothalamic disease in patients with craniopharyngioma – Clinical Endocrinology (free)
Meta-Analysis: Lipid-lowering Agents in Older Individuals
27 Mar, 2019 | 05:52h | UTC
Guideline: Pharmacological Management of Osteoporosis in Postmenopausal Women
26 Mar, 2019 | 01:59h | UTCNews Release: Many postmenopausal women do not receive treatment for osteoporosis (free)
Commentary: Managing Osteoporosis in Postmenopausal Women: An Endocrine Society Guideline – Endocrinology Advisor (free)
See also: Point of Care Algorithm (free)
Thyrotoxicosis: Diagnosis and Management
26 Mar, 2019 | 01:43h | UTCThyrotoxicosis: Diagnosis and Management – Mayo Clinic Proceedings (free)
Related: Thyroid Storm: A Japanese Perspective (free study and commentary)
Treatment of Diabetes in Older Adults: An Endocrine Society Clinical Practice Guideline
25 Mar, 2019 | 00:52h | UTCNews Release: Treating diabetes in older adults requires simpler medication regimens, looser glycemic targets – The Endocrine Society (free)
Consensus Statement: Ethanol Ablation of the Thyroid Nodules
24 Mar, 2019 | 20:42h | UTC
Obesity Treatment, Beyond the Guidelines: Practical Suggestions for Clinical Practice
22 Mar, 2019 | 07:09h | UTCObesity Treatment, Beyond the Guidelines: Practical Suggestions for Clinical Practice – JAMA (free for a limited period)
Related: European Practical and Patient-Centred Guidelines for Adult Obesity Management in Primary Care – Obesity Facts (free)
Cohort Study: Long-Term Consumption of Sugar-Sweetened and Artificially Sweetened Beverages and Risk of Mortality
21 Mar, 2019 | 06:30h | UTCCommentaries: ‘Just one sugary drink a day’ linked to health problems – NHS Choices (free) AND Sugary drinks linked to higher risk of premature death, especially for women, study says – CNN (free) AND Sugary drinks could raise risk of early deaths finds study – News Medical (free)
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease
17 Mar, 2019 | 21:48h | UTCPresented at the American College of Cardiology (ACC) 2019 Scientific Session.
Guideline Hub: Primary Prevention of Cardiovascular Disease (free resources)
Executive Summary: 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease (free PDF)
Guidelines Made Simple: A Selection of Tables and Figures (free PDF)
Summary with Key Points to Remember: 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease – American College of Cardiology (free)
Cohort Study: Associations of Dietary Cholesterol or Egg Consumption with Incident Cardiovascular Disease and Mortality
17 Mar, 2019 | 18:50h | UTCAssociations of Dietary Cholesterol or Egg Consumption With Incident Cardiovascular Disease and Mortality – JAMA (free for a limited period)
Commentaries: Are Eggs Good Or Bad? How You Should Interpret This Latest Study – Forbes (free) AND Are eggs good or bad for you? New research rekindles the debate – STAT (free) AND Eggs are bad – then good – then bad again? What gives? – Diet Doctor (free)
Related Commentary on Twitter
Disagrees with several notable papers:
In NHS & HPFS, eggs not assoc w MI or stroke. https://t.co/F1OcIr0GjZ
In China Kadoorie study, eggs assoc w LOWER risk of CVD.https://t.co/MX6NTPfdhJ
Meta analysis: eggs assoc w LOWER stroke, no assoc w MI.https://t.co/UOFLKBw8dv https://t.co/oX6I6uvXaa
— Andrew Mente, PhD (@andrewmente) March 15, 2019
Review: Perioperative Management of the Diabetic Patient Referred to Cardiac Surgery
17 Mar, 2019 | 18:16h | UTC
Evidence Evolving on Aspirin as Prevention
13 Mar, 2019 | 06:04h | UTCEvidence evolving on aspirin as prevention – ACP Internist (free)
Related: Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease (link to abstract and commentaries) AND Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes (link to abstract and commentaries) AND Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly (link to abstract and commentaries) AND Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events (link to abstract and commentaries)
“In patients who have not had a prior cardiovascular event, aspirin’s protective effects are modest and may not necessarily outweigh its potential downsides (namely, risk of bleeding and hemorrhagic stroke).”
Randomized Trial: Thyroidectomy vs. Medical Management for Euthyroid Patients with Hashimoto Disease and Persisting Symptoms
12 Mar, 2019 | 17:28h | UTCThyroidectomy Versus Medical Management for Euthyroid Patients With Hashimoto Disease and Persisting Symptoms: A Randomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Thyroidectomy Seems to Improve Quality of Life in Hashimoto Disease – NEJM Journal Watch (free) AND Thyroidectomy more effective than medication for Hashimoto disease with persisting symptoms – 2 Minute Medicine (free)
“Results are applicable only to a subgroup of patients with Hashimoto disease, and follow-up was limited to 18 months.”