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Endocrinology (all articles)

Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes

7 Mar, 2019 | 02:37h | UTC

Associations of statin use with glycaemic traits and incident type 2 diabetes – British Journal of Clinical Pharmacology (free PDF)

Commentaries: Statins associated with 38 per cent increased risk of type 2 diabetes – Diabetes.co.uk (free) AND Cholesterol-lowering drugs linked to higher risk for developing type 2 diabetes – News Medical (free)

 

 


Review: Glucose Control in the ICU

6 Mar, 2019 | 01:27h | UTC

Glucose control in the ICU – Current Opinion in Anesthesiology (free)

Source: Critical Care Reviews Newsletter

 


Meta-Analysis: High-intensity Interval Training (HIIT) vs. Moderate-intensity Continuous Training for Weight Loss

4 Mar, 2019 | 00:13h | UTC

Is interval training the magic bullet for fat loss? A systematic review and meta-analysis comparing moderate-intensity continuous training with high-intensity interval training (HIIT) – British Journal of Sports Medicine (link to abstract – $ for full-text)

Commentaries: The Best Type of Exercise to Burn Fat – The New York Times (10 articles per month are free) AND Short bursts of intense exercise ‘better for weight loss’ – BBC (free) AND Short intense exercise regimes may aid weight loss – OnMedica (free)

 

Related Commentary on Twitter

 


Review: Immune Checkpoint Inhibitors-induced Endocrinopathies in Cancer Patients

25 Feb, 2019 | 00:55h | UTC

Spectrum of immune checkpoint inhibitors-induced endocrinopathies in cancer patients: a scoping review of case reports – Clinical Diabetes and Endocrinology (free)

Related Guidelines: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)

 


Study: Diagnostic Performance of Practice Guidelines for Thyroid Nodules

25 Feb, 2019 | 00:40h | UTC

Diagnostic Performance of Practice Guidelines for Thyroid Nodules: Thyroid Nodule Size versus Biopsy Rates – Radiology (free)

Related Guidelines: 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer (free) AND Ultrasonography Diagnosis and Imaging-Based Management of Thyroid Nodules: Revised Korean Society of Thyroid Radiology Consensus Statement and Recommendations (free) AND ACR Thyroid Imaging, Reporting and Data System (TI-RADS): White Paper of the ACR TI-RADS Committee (free)

 


Study: Preventing Misdiagnosis of Diabetes in the Elderly Through Age-dependent HbA1c Reference Intervals

22 Feb, 2019 | 01:36h | UTC

Preventing misdiagnosis of diabetes in the elderly: age-dependent HbA1c reference intervals derived from two population-based study cohorts – BMC Endocrine Disorders (free)

Commentary: Should HbA1c cutoffs for DM diagnosis be higher in older adults? – Univadis (free registration required)

 

Related Commentary on Twitter

 


Subclinical Hypothyroidism: When to Treat

18 Feb, 2019 | 21:49h | UTC

Subclinical hypothyroidism: When to treat – Cleveland Clinic Journal of Medicine (free)

Related: Thyroid Hormone Treatment Does Not Help Adults with Mildly Abnormal Thyroid Tests (link to abstract and commentaries) AND Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism (free study and commentary)

 


Pediatric Obesity Algorithm: A Practical Approach to Obesity Diagnosis and Management

18 Feb, 2019 | 21:44h | UTC

Pediatric Obesity Algorithm: A Practical Approach to Obesity Diagnosis and Management – Frontiers in Pediatrics (free)

 


Diabetes Poland 2019 Guidelines for the Management of Diabetes

12 Feb, 2019 | 15:32h | UTC

2019 Guidelines on the management of diabetic patients. A position of Diabetes Poland – Clinical Diabetology (free PDF)

Related Guidelines: ADA 2019 Standards of Medical Care in Diabetes (free supplement) AND AACE/ACE Comprehensive Type 2 Diabetes Management Algorithm 2019 – Endocrine Practice (Free PDF and Slide Presentations) AND Diabetes Canada 2018 clinical practice guidelines for the prevention and management of diabetes in Canada (free)

 


Review: Identifying and Managing Younger Women at High Risk of Cardiovascular Disease

12 Feb, 2019 | 00:21h | UTC

Identifying and managing younger women at high risk of cardiovascular disease – Canadian Medical Association Journal (free for 7 days)

Related Reviews: Knowledge, Attitudes, and Beliefs Regarding Cardiovascular Disease in Women: The Women’s Heart Alliance – Journal of the American College of Cardiology (free)

Related guidelines: Preventing and Experiencing Ischemic Heart Disease as a Woman: State of the Science: A Scientific Statement From the American Heart Association (free) AND Acute Myocardial Infarction in Women: A Scientific Statement From the American Heart Association (free) AND AHA/ACOG: Reduction of Cardiovascular Disease in Women Through Collaboration with Obstetricians and Gynecologists (free)

 


Study: Only a Minority of Adults and Youth with T1D Achieve ADA goals for HbA1c

11 Feb, 2019 | 21:03h | UTC

State of Type 1 Diabetes Management and Outcomes from the T1D Exchange in 2016–2018 – Diabetes Technology and Therapeutics (free)

Commentary: Minority of patients with type 1 diabetes achieve ADA goals for glycemic control, study finds – ACP Diabetes (free)

 


Randomized Trial: Intense IV Blood Sugar Control Doesn’t Improve Stroke Outcomes

11 Feb, 2019 | 00:15h | UTC

Intense IV blood sugar control doesn’t improve stroke outcomes – American Stroke Association Late Breaking News Brief, Abstract (free)

Commentaries: NIH study provides answer to long-held debate on blood sugar control after stroke – National Institute of Health (free) AND Stroke: Intensive Blood Sugar Control Did Not Improve Outcomes – MedicalResearch.com (free) AND Live from the ISC: Standard treatment of hyperglycaemia in acute ischaemic stroke outperforms an intensive approach – NeuroNews (free)

Related Cochrane Review: Insulin for glycaemic control in acute ischaemic stroke (free) AND Summary: Controlling high blood sugar levels with insulin in people who have had an acute ischaemic stroke (free)

“Intensive glucose control (80–130mg/dL) does not improve 90-day functional outcome and increases the risk of severe hypoglycaemia.” (from NeuroNews)

 


Systematic Review Supports Lengthening of the Screening Interval of Patients with Type 2 Diabetes Without Retinopathy at Last Screening Session

10 Feb, 2019 | 23:58h | UTC

Incidence of sight‐threatening diabetic retinopathy in people with Type 2 diabetes mellitus and numbers needed to screen: a systematic review – Diabetic Medicine (free PDF)

Commentary: How often should patients with T2D be screened for retinopathy? – Univadis (free registration required)

Related: Evidence‐based Guidelines for Screening of Diabetic Retinopathy (free)

“This review supports lengthening of the screening interval of patients with Type 2 diabetes without retinopathy at last screening session”

 


Cohort Study: Effect of Gastric Bypass Surgery on Diabetes Remission and Complications

10 Feb, 2019 | 15:44h | UTC

Effect of Roux-en-Y gastric bypass surgery on diabetes remission and complications in individuals with type 2 diabetes: a Danish population-based matched cohort study – Diabetologia (free for a limited period)

Commentary: Gastric Bypass Surgery Linked to Diabetes Remission – MedicalResearch.com (free)

 


Study: Association of Thyrotropin Suppression with Survival Outcomes in Patients With Intermediate- and High-Risk Differentiated Thyroid Cancer

10 Feb, 2019 | 13:59h | UTC

Association of Thyrotropin Suppression With Survival Outcomes in Patients With Intermediate- and High-Risk Differentiated Thyroid Cancer – JAMA Network Open (free)

Commentary: Study Evaluates Thyroid Hormone Suppression For High Risk Thyroid Cancer – MedicalResearch.com (free)

“This study provides the justification for a randomized trial.”


Randomized Trial: Alirocumab for Secondary Prevention of Cardiovascular Disease

10 Feb, 2019 | 13:57h | UTC

Alirocumab Reduces Total Nonfatal Cardiovascular and Fatal Events: The ODYSSEY OUTCOMES Trial – Journal of the American College of Cardiology (free)

Commentary: Alirocumab reduces risk of initial and repeat CV events after ACS – Cardiovascular Business (free)

Original Research: Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome (link to abstract and commentaries)

 


JAMA Clinical Guidelines Synopsis: Management of Blood Cholesterol

4 Feb, 2019 | 23:53h | UTC

Guideline Synopsis: Management of Blood Cholesterol – JAMA (free)

Editorial: A New Personalized, Patient-Centric, and Cost-Conscious Guideline for Contemporary Cholesterol Management (free)

Original Guideline: New AHA/ACC Guideline on the Management of Blood Cholesterol (free guideline and resources)

 


“Lorcaserin in Obesity: Minimal Benefits and Ill-Defined Harms”

4 Feb, 2019 | 22:16h | UTC

EBM Verdict: Lorcaserin in obesity: minimal benefits and ill-defined harms – BMJ Evidence Based Medicine (free)

 


Worldwide Dyslipidemia Guidelines

4 Feb, 2019 | 22:32h | UTC

Worldwide Dyslipidemia Guidelines – Current Cardiovascular Risk Reports (free)

Related: JAMA Clinical Guidelines Synopsis: Management of Blood Cholesterol (free guideline and synopsis)

 


Cholesterol-Lowering Agents: PCSK9 Inhibitors Today and Tomorrow

4 Feb, 2019 | 22:19h | UTC

Cholesterol-Lowering Agents: PCSK9 Inhibitors Today and Tomorrow – Circulation Research (free for a limited period)

 


Meta-Analysis: Efficacy and Safety of Statin Therapy in Older People

3 Feb, 2019 | 15:43h | UTC

Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials – The Lancet (free)

Commentaries: Never too old for statin treatment? – The Lancet (free) AND Efficacy and safety of statin therapy in older people – expert comment – London School of Hygiene & Tropical Medicine (free) AND Expert reaction to meta-analysis looking at statins and cardiovascular events in all ages – Science Media Centre (free) AND Statin therapy reduces cardiovascular disease risk in older people – University of Oxford (free) AND Statins Lower Risk for CV Events in Elders, But Benefits for Primary Prevention Still in Question – NEJM Journal Watch (free)

“However, when stratified by history of vascular disease, a significant benefit among those aged 71 and older was limited to those with prior vascular disease.” (from NEJM Journal Watch)

 


AACE/ACE Comprehensive Type 2 Diabetes Management Algorithm 2019

1 Feb, 2019 | 02:50h | UTC

AACE/ACE Comprehensive Type 2 Diabetes Management Algorithm 2019 – Endocrine Practice (Free PDF and Slide Presentations)

Related Guidelines: ADA 2019 Standards of Medical Care in Diabetes (free supplement) AND Diabetes Canada 2018 clinical practice guidelines for the prevention and management of diabetes in Canada (free)

 


Study: Patients with Type 2 Diabetes Safely Switched from Analog to Less Costly Human Insulin

30 Jan, 2019 | 01:13h | UTC

Implementation of a Health Plan Program for Switching From Analogue to Human Insulin and Glycemic Control Among Medicare Beneficiaries With Type 2 Diabetes – JAMA (link to abstract – $ for full-text)

Commentary: Medicare Patients with Type 2 Diabetes Safely Switched From Analog to Human Insulin, JAMA Study Finds – AJMC (free)

Related: Meta-Analysis: Comparative Benefits and Harms of Basal Insulin Analogues for Type 2 Diabetes (link to abstract and commentaries) AND Retrospective Observational Study: Basal Insulin Analogs vs NPH Insulin for Type 2 Diabetes (link to abstract and commentaries)

“Patients with type 2 diabetes (T2D) enrolled in a CareMore Health Medicare Part D plan switched from analog to human insulin without significant loss of glycemic control while saving millions for themselves and for the health plan.: (from AJMC)

 


Consensus Statement: Targeted Treatment of Primary Aldosteronism

29 Jan, 2019 | 22:01h | UTC

Targeted treatment of primary aldosteronism – The consensus of Taiwan Society of Aldosteronism – Journal of the Formosan Medical Association (free)

 


European Practical and Patient-Centred Guidelines for Adult Obesity Management in Primary Care

29 Jan, 2019 | 00:07h | UTC

European Practical and Patient-Centred Guidelines for Adult Obesity Management in Primary Care – Obesity Facts (free)

 


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